-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bladder-cancer-non-muscle-invasive_research-protocol.pdf
July 21, 2014 - ,
year, setting, country, sample size, eligibility criteria, population and clinical
characteristics … They will have a serious or “fatal” flaw
or flaws in design, analysis, or reporting; large amounts of … The results of
these studies will be at least as likely to reflect flaws in the study design as the … populations (e.g., demographic characteristics; stage of
disease; performance status); interventions; the sample … size of the studies; and
settings (e.g., patients in developing countries) in which the studies are
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-pain-opioid-treatment_research-protocol.pdf
December 19, 2013 - , year, setting, country, sample
size, eligibility criteria, population and clinical characteristics … They will have a serious or “fatal” flaw
in design, analysis, or reporting; large amounts of missing … severity of pain,
underlying pain condition, presence of medical and psychiatric co-
morbidities); the sample … size of the studies; and clinical settings (e.g., primary
care, specialty setting) and countries (e.g … Therefore study questions, design and/or methodological
approaches do not necessarily represent the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/appendicitis_research-protocol.pdf
December 09, 2013 - because our preliminary searches indicate that non–English-
language studies are few and have small sample … sizes; as such, they are unlikely to affect
our conclusions. … of diagnostic tests
and will include elements that address population characteristics, sample size, … study
design, descriptions of the index and reference standard tests of interest, analytic details, … Studies of different designs will be graded within the context of their
study design.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ear-infection_executive.pdf
May 01, 2013 - We examined several design, placement, and material
features of TTs. … Sizes) Outcome and Results
Strength
of Evidence
Oral steroids +
antibiotics vs. … Sizes) Outcome and Results
Strength
of Evidence
TT vs. … Strength of evidence for subgroups
Intervention and
Comparator
Number of Studies
(Sample Sizes) Outcome … size
needed to find an effect (the RCTs of Williamson et al.,
the MRC, and Paradise et al. being notable
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-research-report-pilot-promote-entry-data-srdr_0.pdf
October 01, 2019 - Screenshot of the MS Excel File Template for Importing Data Into the SRDR
Design Tab
Appendix C. … We restricted the sample size to nine respondents. … Limitation to Survey
The small sample size (nine respondents) is an important limitation to the findings … Screenshot of the MS Excel File Template
for Importing Data Into the SRDR Design Tab
C-1
Appendix … Screenshot of the MS Excel File Template for Importing Data Into the SRDR Design Tab
Appendix C.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_disposition-comments.pdf
April 03, 2013 - Authors tended to overstate positive effects while omitting adequate
examination of study design and … Studies with too small a sample size often
have other more covert problems as well. … Anonymous
Public
Reviewer #2
Results 64: Table 20 states the Hien et al. 2004 is "unclear" as to sample … sizes per arm; those
sample sizes are in fact stated in the Hien article (pg. 1428)—n=41 SS, n=34 RP … It
does not meet eligibility
criteria, based on study
design.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - For quantitative analyses, we
included all eligible studies without sample size
limitations. … concluded that we could not
conduct any quantitative analyses, then we included
studies only if they had sample … sizes of 40 or larger. … We
included observational studies that had large sample
sizes (1,000 patients or more), lasted at least … Results are limited by study
design; differences in outcomes are of unknown clinical significance.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_executive.pdf
May 01, 2010 - The single randomized, controlled
trial had too small of a sample size and too short of a
followup to
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
March 01, 2015 - could discern that the articles did not meet one or more
of the inclusion criteria relating to study design … data were abstracted:
• Trial characteristics: Author, year, country, number of
trial sites, trial design … effects of nonhormone
therapies contained the following information: condition,
treatment, study design
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveill-report-1.xlsx
September 30, 2015 - Randomized controlled trials
Author, Year Study Design
Duration Setting
Country Eligibility Criteria … C: aOR 0.28 (95% CI 0.13 to 0.62)
Note: ADL and IADL not calculated due to small sample size
Patients
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/smoking-pregnancy-infants_research-protocol.pdf
March 11, 2013 - The team
established this minimum sample size to balance the need for smaller studies of
specialized … populations (e.g., studies in specific ethnic groups) with the need for studies
with sample sizes large … size, study type, intervention(s) and comparator(s),
population characteristics, baseline data, and … sizes), the quality of evidence (from the quality ratings on
individual articles), and the coherence … Not a study design of interest
43. Rosewich M, Adler S, Zielen S.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-195-uterine-fibroids-final.pdf
December 01, 2017 - published as candidate covariates
and we stratify by prospective versus retrospective study
3
design … size,
but strength of evidence is low because of short followup
and poor quality of overall study design … the range of the point estimates that others have
produced.10,24,25 Our analysis includes a larger sample … size,
more prospective studies, and more recently published
data. … Future Research
Key components of study design, analysis, and reporting
remain the leading weaknesses
-
effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_disposition-comments.pdf
February 29, 2016 - TEP
Reviewer #6
Lines 44-49 on page 15 are not clearly
written
We revised the description of
sample … sizes to be clearer: “The
sample size was 456 in one trial
and ranged from 40 to 70 in the
others … almost all trials used an un-blinded
design and trials frequently had
high attrition. … almost all trials used an un-blinded
design and trials frequently had
high attrition. … The
large sample sizes of these trials also
inform the applicability of this review's
conclusions
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-prevention-covid-healthcare-community-amended-protocol.pdf
July 02, 2020 - Data extracted will include author,
year, country, study design, study dates, sample size, intervention
-
effectivehealthcare.ahrq.gov/sites/default/files/worker-health_executive.pdf
April 01, 2016 - Several studies had small sample sizes
and thus lacked power for determining intended
effects. … limitations that included differences between
intervention and comparison groups at baseline, small
sample … sizes and power, high overall or differential
attrition, and choices of statistical analyses (e.g., … randomization and allocation
concealment, differences in intervention and control
groups at baseline, small sample … sizes (and thus lack
of power for determining intended effects), lack of
clarity in defining intervention
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-the-risk-of-bias_draft-report.pdf
June 02, 2011 - o Assess risk of bias based on study design and conduct rather than reporting. … The impact of random error on
the precision of estimates can be reduced by increasing sample size. … inclusion of random error in this definition of quality, quality assessment tools have included
sample … size evaluation as an explicit component in the past. … Quaisi-experimentation: design and analysis issues for field settings.
-
effectivehealthcare.ahrq.gov/sites/default/files/adhd_executive.pdf
October 01, 2011 - Study authors were contacted via email for missing
outcome or design data. … From a design hierarchy
perspective, comparative group designs provide
stronger evidence for efficacy … of evidence (SOE):
• Study limitations (predominantly riskofbias
criteria)
• Type of study design … XR.63,65 Concerns
about exacerbation of tics with stimulants appear to be
unfounded, although the sample … size remains small and
may result in type II error.58,62 Use of psychostimulants
slows the rate of
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
December 11, 2018 - , year,
setting, country, sample size, eligibility criteria, attrition, population and clinical
characteristics … The results of these studies
are at least as likely to reflect flaws in the study design as the true … quality, heterogeneity across studies with regard to
patient population, intervention and outcomes, and sample … size will be considered
as will statistical tests for heterogeneity. … When quantitative
synthesis is not possible, sample size and assessment of variance within
individual
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
September 01, 2011 - Therefore, trials require
large sample sizes with long followup periods. … reporting of serious adverse events; a
predominance of case reports and uncontrolled series;
small sample … sizes in most series and RCTs; a limited
number of studies for many individual DMARDs; and
frequent
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/skin-cancer_research-protocol.pdf
August 10, 2016 - The basic elements and design of the extraction form will be the similar to those
used for other AHRQ … exposures, and comparators analyzed; outcome definitions; effect
modifiers; enrolled and analyzed sample … sizes; study design features; funding source;
results; and risk of bias questions. … These included descriptions of the study design,
sample size, interventions, followup duration, outcomes … Therefore
study questions, design, and methodological approaches do not necessarily represent the
views