-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/tinnitus_research-protocol.pdf
February 22, 2012 - study characteristics
(i.e., population characteristics, treatment interventions, study outcomes, sample … sizes, settings, funding
sources, and comparator treatments [type, duration, and provider]), methodological … diagnostic accuracy outcomes, and the
effect size for treatment monitoring; this domain is related to study sample … size)
5. … ☐ ☐ ☐
Was the sample size justified?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
April 20, 2015 - For all articles, reviewers will extract information on general study characteristics (e.g., study
design … protection against
bias (i.e., good internal validity), assessed
through main elements:
• Study design … • Variability in study results is explained by
differences in study design, patient population
or … study will
get listed in the appendix with the
following data:
Author, publication year
Study design … Therefore study questions, design, and methodological approaches do not
necessarily represent the views
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-treatment_executive.pdf
May 01, 2011 - Major elements abstracted included study
location; study design; recruitment setting and approach; … small number of trials, most of which were at
moderate risk of bias due to factors such as small
sample … sizes, high or differential attrition, and lack
of appropriate blinding … included in the
review, and the only minor flaws were retention of less
than 90 percent and small sample … size.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_surveillance.pdf
January 01, 2013 - The sample sizes of the
included studies ranged from 63 to 92
glaucoma participants and 41 to 95
healthy … The range of sample size was 25
to 174 glaucomatous eyes and 15 to
164 healthy eyes. … (not clear this study
applies to
screening)
Study
Region
Study Design
Populations (n … The sample sizes of
the included studies ranged from 63 to 92
glaucoma participants and 41 to 95 healthy … The range of sample size was 25 to 174
glaucomatous eyes and 15 to 164 healthy eyes.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disparities-quality-improvement_disposition-comments.pdf
August 27, 2012 - You
might even consider a new heading for Sample Size. … We have inserted a level two heading for
“Sample Size”. … I
think the footnote belongs in the text along with the
description of sample size – it makes little … We have
deleted the table footnote and added a
section for “Sample Size”. … As noted by
the authors, this was an estimate for minimum required
sample size.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments-rapid-review.pdf
March 01, 2024 - Appendix C, the
evidence and risk of bias table, displays details such as design, intervention, comparator … non-serious adverse
events, effectiveness outcomes
Timing No restriction Not applicable
Study Design … -3
The following data were abstracted:
• Study identifier (author) and publication year
• Study design … EHC011
March 2024
C-2
Author, Year
Related Studies
Trial ID
Location
Setting
Study Design … EHC011
March 2024
C-3
Author, Year
Related Studies
Trial ID
Location
Setting
Study Design
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-195-disposition-comments-uterine-fibroids.pdf
December 14, 2017 - No definite conclusions due to insufficient data, sample size
or number of studies.
2. … specify
that for questions of effectiveness (KQ 1-2) there was restriction
to RCTs, but different design … TEP Reviewer#4 Discussion/
Conclusion
But to determine appropriate sample sizes we need to know
what … Are the sample sizes significant? … size.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-treatment_research-protocol.pdf
November 08, 2011 - Sample size restrictions will not be set a priori, and case series may be
used; however, case studies … They will have a serious or “fatal” flaw in design, analysis, or reporting;
large amounts of missing … The results of these studies will be at least as likely to reflect flaws
in the study design as the … or imprecise)
We will also estimate publication bias by examining whether studies with smaller sample … sizes
tended to have positive or negative assessments of pressure ulcer treatment.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_disposition-comments.pdf
June 28, 2013 - Other sample
sizes are included in the study characteristics tables
provided in Appendix F. … sizes of each study
We have added in columns of the sample sizes for
all the tables as requested. … We have
therefore left off the sample size in the forest plots
but have instead included the number … Other
sample sizes are included in the study
characteristics tables provided in Appendix F. … Other
sample sizes are included in the study
characteristics tables provided in Appendix F.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
June 01, 2012 - inclusion and exclusion criteria
Study Characteristic Inclusion Criteria Exclusion Criteria
Study design … Second, the sample size and low representation
of women in most of the comparator studies may affect … Studies of sufficient sample size and representation
of women. … size calculation for the numbers needed per group. … size is required to have adequate statistical power
for subgroup analyses.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/binge-eating_executive.pdf
December 01, 2015 - : 304
Wrong sample size: 32
Not an intervention or comparison or interest: 7
Wrong timing: 19
Wrong … Sizes) Outcome and Results
Strength
of Evidence
Topiramate vs. … Other issues in the
overall evidence base included small sample sizes (and
thus lack of power for determining … Investigators should increase
the sample sizes on which they base conclusions about
treatment effectiveness … An additive design. Behav Ther. 1994;25(2):225-38.
25. Ricca V, Mannucci E, Mezzani B, et al.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/research-protocol-osteoporosis_2.pdf
October 05, 2018 - PICOTS (Populations, Interventions, Comparators, Outcomes, Timing, Settings/Study Design)
KQ Population … Intervention Comparator Health
Outcomes &
Harms
Timing Setting Study Design
KQ 1:
Long-term … Study Design • All key questions: RCTs, CCTs
• For assessment of harms (KQ 3, 4, 7 & 8):
• Also … o Rare harms (i.e., AFF, ONJ, Afib): Sample size must be >100 and may include case-control, retrospective … o Nonrare harms: Sample size must be >1000 and limited to prospective cohort studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
September 01, 2014 - Furthermore, for Key Question 2 we included any primary
research articles, regardless of design, that … We determined risk of bias (low, medium, or high) on the
basis of the study design and the methodological … compared to studies using surgical pathology results
for all patients) and studies with a prospective design … (as
compared to studies with a retrospective design). … MRI-guided biopsies were
evaluated in only six studies with small sample sizes,
leading to substantial
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-executive-summary.pdf
October 01, 2022 - inclusion criteria, and we entered all critical
information into evidence tables, including study design … , country, funding source, study
duration, sample size, eligibility criteria, population characteristics
-
effectivehealthcare.ahrq.gov/sites/default/files/transcript_deliberativemethodswebinar.pdf
April 19, 2012 - There is no one size or
one shape fits all design. … I think, ideally, key design decisions should really be
informed, as we’ve heard already, by the goals … And in
these cases one might want to consider a design that has a
longer timeframe. … So a few more points, just on these three design features. … If
you think about the fact that all of that careful design
work, facilitation, et cetera, leads
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - The purpose of this paper is to review the types of missing data in patient registries, discuss
design … However, limiting the registry enrollment to only those newly diagnosed patients would
reduce the sample … size significantly, and, in the case of a rare disease, likely render the registry
infeasible. … throughout the planning and design phases
of the registry’s lifecycle. … Strategies for dealing with missing data in
clinical trials: from design to analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/measuring-blood-pressure_research-protocol.pdf
April 11, 2011 - No minimum sample size.
KQ 2
Population: same as for KQ 1. … Study Design: same as for KQ 1.
KQ 3 Population: same as for KQ 1. … Study Design: same as for KQ 1.
KQ 4
Population: same as for KQ 1. … Study Design: same as for KQ 1.
KQ 5
Population: same as for KQ 1. … Studies of different study designs will be graded within
the context of their study design.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ocr-protocol-final_1.pdf
December 18, 2019 - , year, setting, country, sample size, eligibility criteria, population and
clinical characteristics … They will have a serious or “fatal” flaw in design, analysis, or reporting;
large amounts of missing … The results of these studies will be least as likely to reflect flaws in
the study design as the true … This may be based on sufficiency of sample size and number of events,
and if these are adequate, the … , year, setting, country, sample size, eligibility criteria, population and clinical characteristics,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_disposition-comments.pdf
August 23, 2012 - In addition to total sample size, it would be helpful
to add the number of patients with the diagnosis … improved
clinical practice with the incorporation of sFLC analysis, it will
be nearly impossible to design … assay is increasingly incorporated into clinical practice,
but we believe that it would be possible to design … inconclusive the conclusions cannot be use to inform policy
and/or practice decisions but can guide the design … I think,
however, there are a few flaws in the study design and
results, and therefore the conclusions
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
October 29, 2012 - The
sample size of the studies ranged from 45 15 to 2739 7. … Or 2) a trial not published in the above top 5 journals but have a sample size of at least triple the … /127 (13) vs. 40/120 (33); p=
52
Author year
Study name
(if applicable)
Study
design … 55
Author year
Study name
(if applicable)
Study
design
Subjects
Treatment groups … Control
59
Author year
Study name
(if applicable)
Study
design
Subjects