-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_executive.pdf
April 01, 2013 - size, prospective cohort studies with a sample size
of at least 500, and case-control studies with … a sample size
of at least 500. … 77a
# of records excluded:
2,521
# of full-text articles excluded, with reasons:
380
Wrong study design … For KQs 1 through 5, we included RCTs with no sample
size limit; we did not allow for inclusion of observational … size of
500 or greater.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/incident-user-design_research.pdf
May 01, 2012 - design. … We also reviewed methods papers on the incident user design. … Issues That Motivate the Incident User Design
Investigators struggle to design non-randomized studies … The Incident User Design Complements Propensity
Score Analyses
The incident user design results in … incident user design results from the other design and analysis options
that it allows, which may improve
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_executive.pdf
July 01, 2012 - Study design
2. PCMH components
3. Settings (e.g., practice size, geographic location)
4. … Study design KQ 1, KQ 4: Patient or cluster RCT, nonrandomized
clustered controlled trial, controlled … & Magnitude of
Effecta,b,c]
Number
of Studies
(Subjects)
SOE Domain–
Risk of Bias:
Study Design … & Magnitude of
Effecta,b,c]
Number
of Studies
(Subjects)
SOE Domain–
Risk of Bias:
Study Design … Building the Evidence
Base for the Medical Home: What Sample and Sample Size
Do Studies Need?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_disposition-comments.pdf
September 28, 2015 - Peer Reviewer 1 Methods It is not clear whether the mean differences were
weighted by sample size and … If not, then small and large studies
Studies were weighted by sample size and variance. … Peer Reviewer 4 Results Table 10, I would suggest to adding the sample size in
each node. … We have added the sample sizes. … Some nodes had very
few studies, small sample sizes, and/or wide
credibility intervals, thus we did
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-interventions-maltreatment-child_executive.pdf
April 01, 2013 - was
largely attributable to most bodies of evidence consisting
of only one trial, many with small sample … sizes. … Sample sizes are commonly
very small. … Statistical Considerations: Even with concerns about
limited sample sizes and attrition, few studies … sizes and extensive heterogeneity of design, definitions,
and outcomes, among other considerations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_executive.pdf
April 01, 2012 - Inadequate sample size was a factor in many studies. … Adequate sample
size was an issue in these studies. … Sample sizes in future research studies should be
sufficient to establish important margins of difference … Extant studies
are limited in type of agents utilized, sample sizes, and
population characteristics … A second study, a pilot with small
sample size evaluating dose escalation, showed no effect.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-protocol-amendment.pdf
January 22, 2024 - In terms of study design, we expect to include a variety of non-randomized study
designs because very … We will not restrict by sample size or study
quality. … Key
Questions
No sample size
restriction
For Key Question 1 for
EMS populations, we will
After … No sample size restriction
will apply to studies of
911 populations. … Because KQ 1 is
largely about
epidemiology
(incidence,
prevalence, and
severity), a sample
size
-
effectivehealthcare.ahrq.gov/sites/default/files/masks-surveillance-2-appendix-table-a-2.xlsx
March 01, 2020 - Masks in the Community
Virus Strain Author Publication Year Title Date Retrieved Source Link/URL Study Design … Study Dates Geographic Setting Setting Inclusion Criteria Sample Size Age (mean, years) Female (%) Definition
-
effectivehealthcare.ahrq.gov/sites/default/files/Masks-appendix-table-b-2-surveillance-report.xlsx
March 01, 2020 - Masks in the Community
Virus Strain Author Publication Year Title Date Retrieved Source Link/URL Study Design … Study Dates Geographic Setting Setting Inclusion Criteria Sample Size Age (mean, years) Female (%) Definition
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment-future_research.pdf
September 01, 2012 - Studies with larger sample sizes, including multicenter trials;
3. … Additionally, it was noted that all study designs should account for the need for
larger sample sizes … However, such trials would need large sample sizes in order to
account for presumably small-to-modest … Studies with larger sample sizes, including multicenter trials;
3. … Additionally, it was noted that all study designs should account for the need for
larger sample sizes
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
March 01, 2018 - Comparison of the sample size, primary outcome, and withdrawals due to adverse
events reported in the … Data extraction elements
Trial design Design (parallel or crossover)
Number of groups
Trial start … Two reviewers compared the planned sample size, the primary outcome, and the analysis
plan specified … • Comparison of prespecified statistical plan
• Sample sizes, total. … Sample
Size
Followup
Published
literature only
Karmakar, 201435 Not found NA NA NA 28 6 weeks
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/single-group-studies_white-paper.pdf
January 01, 2013 - authors planned to
use single group studies, selection criteria for single group studies (minimum sample … size,
followup duration, or ―other‖), whether the results of different single group studies were … However, this interpretation is limited by the small sample size.
F
Figure 2. … in the randomized two arm trial
designs (though the two arm studies required a 2–4 fold increased sample … size).
24
A third
simulation study compared optimal single group and randomized phase 2 designs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
September 02, 2011 - publication, study location
(e.g., country, city, state) and time period, population description, sample … size, and study type
(e.g., randomized controlled trial, prospective observational study, etc.). … use
established concepts of the quantity of evidence (e.g., numbers of studies, aggregate ending-
sample … sizes), the quality of evidence (from the quality ratings on individual articles), and the
coherence … Therefore study questions, design and/or methodological
approaches do not necessarily represent the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bundled-payments-quality-effects_research-protocol.pdf
June 23, 2011 - Subsets of the bundled payment systems in KQ 1, characterized
by the following key design features: … The impact of these design features are addressed by KQ 2. … represent most or all of the
reviewed studies), still other additional elements will be considered:
o Sample … size. … Therefore study questions, design and/or methodological approaches do not
necessarily represent the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
June 24, 2022 - size
NESTcc Protocol The protocol describes the study registration process
NESTcc Protocol The protocol … CMS Design_precision Larger sample sizes in studies to demonstrate both statistically significant as … definine patients characteristics and inclusion and exclusion criteria
CMS Design_precision Larger sample … sizes in studies to demonstrate both statistically significant as well as clinically significant outcomes … size
NESTcc Protocol The protocol describes the study registration process
NESTcc Protocol The protocol
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/obesity-child_executive.pdf
March 31, 2010 - We did not exclude studies based on study
sample size (Table A). … One
reason for the nonsignificant effect on weight outcomes
might have been that the sample sizes were … There are many differences across studies in term
of settings, design, sample size and characteristics … However, due to the limited sample size, we
could not conduct further stratifications to explore the … Studies With High Statistical Power
We need more studies with large sample sizes and
adequate length
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-protocol.pdf
July 10, 2018 - • Study Design—randomized controlled trials (RCTs) published from January 1, 1980
through present … Randomized controlled trials Studies that do not have a randomized controlled
trial design. … , year, setting, country, sample
size, eligibility criteria, study characteristics, population characteristics … Study design*
j. Number of enrolled participants
k. Diagnostic instrument(s)
l. … Randomized controlled trials
Study Design
Non-English language articles
English language articles
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-protocol.pdf
July 10, 2018 - • Study Design—randomized controlled trials (RCTs) published from January 1, 1980
through present … Randomized controlled trials Studies that do not have a randomized controlled
trial design. … , year, setting, country, sample
size, eligibility criteria, study characteristics, population characteristics … Study design*
j. Number of enrolled participants
k. Diagnostic instrument(s)
l. … Randomized controlled trials
Study Design
Non-English language articles
English language articles
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_clinician.pdf
May 01, 2016 - biopsies were
deemed to have moderate to high risk of bias because of
characteristics related to their design
-
effectivehealthcare.ahrq.gov/sites/default/files/outcome-definition-and-measurement-chapter-6.pptx
January 01, 2013 - frequency and length of followup assessments to be included in the study after initial treatment, and the sample … size, which is influenced by the expected frequency of the outcome in addition to the magnitude of relative … The study power for a given sample size may be increased when such composite measures are used as compared … Study Design and Analysis (1 of 2)
Study Design and Analysis (1 of 2)
Avoidance of Bias in Study … Study Design and Analysis (2 of 2)
Study Design and Analysis (2 of 2)
Study Period and Length of