-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis_research-protocol.pdf
June 06, 2011 - systemic fibrosis, anaphylaxis,
and arrhythmias—and how these events vary by demographic factors
Sample … size
We will not exclude articles based on sample size during the full-text screening but
may revisit … We will design the data abstraction forms for this project to collect the data required
to evaluate … Study design will
be considered when grading quality. … Therefore, study
questions, design, and/or methodological approaches do not necessarily represent the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_executive.pdf
January 01, 2016 - The evidence was limited by low sample size, lack of
comparisons of the same modalities, and variations … Due to low sample size and limitations in
reporting, pain and scarring were found to have insufficient … For Nd:YAG and
carbon dioxide lasers, all studies were severely limited
by sample size, and strength … Due to low sample size and limitations in reporting, pain
and scarring were found to have insufficient … sizes.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
August 01, 2012 - Followup times varied from 3 months to
13 years, with sample sizes of 40 to 399 patients. … /
spectrum bias as well as (in one study) small sample
size. … without
adjustments for potential confounders and as C in the other
five studies because of their small sample … sizes, limited
information about study design, and/or potential selection
bias. … Studies should have an
a priori calculation of the sample size needed to determine
the desired precision
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - Moreover, because of their generally
smaller sample size and shorter duration than NRSIs, RCTs more … Given the relatively
small sample sizes and short duration of most RCTs, they are frequently underpowered … Studies that are conducted using big data
offer the obvious advantage of very large sample sizes (often … Because of large sample sizes, high precision of treatment effect sizes is often attained,
which may … Moreover, because of their generally large
sample sizes, effect size estimates from individual NRSIs
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - Moreover, because of their generally
smaller sample size and shorter duration than NRSIs, RCTs more … Given the relatively
small sample sizes and short duration of most RCTs, they are frequently underpowered … Studies that are conducted using big data
offer the obvious advantage of very large sample sizes (often … Because of large sample sizes, high precision of treatment effect sizes is often attained,
which may … Moreover, because of their generally large
sample sizes, effect size estimates from individual NRSIs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
March 01, 2016 - bleeding symptoms.17 Furthermore, as the
literature evolves, including larger studies of stronger design … We may include in the analysis high of risk of bias studies that have a
large sample size or that evaluate … Many fibroid studies have small sample sizes, which limit the ability of a study to
overcome differences … will use established concepts of the quantity of evidence (e.g., numbers of
studies, aggregate ending-sample … sizes), the quality of evidence (from the quality ratings
on individual articles), and the coherence
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_disposition-comments.pdf
October 23, 2012 - Sometimes an adequate sample size is difficult to achieve
because an outcome under study (such as aggressive … Sample size is of course also limited by attrition
due to death/decline in this population. … Cost is also a big
issue/barrier to obtaining sufficient sample sizes, especially for
non-pharmacological … of the interventions/exposures of interest, more studies
need to be conducted with larger sample sizes … Sample size and
design remain important considerations in terms of validity,
but we agree that the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pain-chronic_research-protocol.pdf
July 28, 2010 - What was the study design?
2. What was the sample size?
3. … What are specific needs to make research in this area effective (e.g., design, definition of pain
program … We will include studies of any sample size, any design (RCT, controlled clinical trial,
uncontrolled … General study factors (design, sample size, country, funding source)
Information related to Question … General Study Factors
Study
Design (RCT, CCT,
Uncontrolled
Observational,
Case Report/Case
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-2-risk-of-reinfection-from-SARSCoV2_0.pdf
December 31, 2022 - sizes for
the available studies were not large. … ~85%), but this value should be interpreted in the context of high precision resulting
from large sample … sizes and low overall counts of reinfection. … sizes or a case-control design would be needed to determine whether vaccination augments protection … sizes and violations of distributional assumptions,
and also has less variance than many alternative
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/cervical-degenerative-protocol.pdf
January 12, 2022 - of spinal cord disease);5,14,24-28 (7) high rate of
industry sponsorship,12 which could influence design … ,
setting, country, funding, sample size, eligibility criteria, attrition, population and clinical … This may be based on sample size sufficiency and number of
events. … When quantitative synthesis is not possible, sample size
and assessment of variance within individual … Therefore,
study questions, design, and methodological approaches do not necessarily represent the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - ASD (ES, Key points) (for individual
SGAs): “smaller sample sizes
contributing to the SOE for each … TEP 7 Methods [page 68]: Authors mention precision evaluated "on
the basis of sample size and, if size … Given the typical small sample sizes within
studies, imbalance between groups is likely to occur. … We
divided the sample size in the control arm by 2
to account for the lower precision from this
approach … We
realized that 2 of the analyses did not split the
sample size for one control group and we re-did
-
effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - ASD (ES, Key points) (for individual
SGAs): “smaller sample sizes
contributing to the SOE for each … TEP 7 Methods [page 68]: Authors mention precision evaluated "on
the basis of sample size and, if size … Given the typical small sample sizes within
studies, imbalance between groups is likely to occur. … We
divided the sample size in the control arm by 2
to account for the lower precision from this
approach … We
realized that 2 of the analyses did not split the
sample size for one control group and we re-did
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-natriuretic-peptide_research-protocol.pdf
December 20, 2011 - and sample size. … sizes, settings, funding sources, comparator treatments (type,
dose, duration, and provider), methodological … accuracy outcomes, and the effect size for treatment monitoring; this
domain is related to study sample … size)
5) Other key domains (publication bias, dose-response association, existence
of plausible … Quality Assessment Form: Cross-Sectional Design and Before-After Design
Study Population
Yes/No
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-executive-summary.pdf
December 01, 2022 - Studies: Effectiveness and implementation studies
frequently employed less rigorous designs, had small sample … sizes, and often did
not minimize bias through design or analyses. … implementation across study sites
• The most frequently identified weakness after overall study design … is small sample
sizes that result in lack of power to detect differencesStudies are also hampered by … included studies of provider-to-provider telehealth for rural patients and what improvements in study design
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-risk-bias.ppt
June 01, 2012 - error
Adequacy of reporting
Aspects of data analysis
Applicability
Specifying ethics approval
Detailing sample … size estimates
No consensus has yet been achieved on the optimal criteria for quality assessment in … adequacy of reporting, aspects of data analysis, applicability, specifying ethics approval, and detailing sample … size estimates. … (Yes/No/Unclear)
Was a case-control design avoided?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-risk-bias.ppt
June 01, 2012 - error
Adequacy of reporting
Aspects of data analysis
Applicability
Specifying ethics approval
Detailing sample … size estimates
No consensus has yet been achieved on the optimal criteria for quality assessment in … adequacy of reporting, aspects of data analysis, applicability, specifying ethics approval, and detailing sample … size estimates. … (Yes/No/Unclear)
Was a case-control design avoided?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-apps-a-e-surveillance-report-2-final_0_0.pdf
March 01, 2022 - size (imprecision). … size (imprecision). … sizes or numbers of studies; (2) narrowness of
enrolled populations (see Tables 6 and 7); (3) lack … , year, setting, country, sample size, eligibility criteria,
population and clinical characteristics … Publication bias (small sample size bias) is
assessed using funnel plots when there are eight or more
-
effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_executive.pdf
February 01, 2016 - evidence included
2 prospective studies and 18 retrospective observational
studies that ranged in sample … size from 84 to 1,726 patients. … dNonrandomized studies must have a minimum sample size of 500 participants.
Table A. … continued)
PICOTS Diagnostic (KQs 1, 2a, and 2b) Management (KQs 3a and 3b)
Type of study Any study design … addressed KQ
3 is listed in the appendix with the following data:
• Author, publication year
• Study design
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-use-disorder_research-protocol.pdf
February 24, 2016 - Study design/size
iv. Comparator used in comparative studies
v. … reviewing the literature, such as outcomes to be prioritized,
meaningful length of followup, study design … pregnant women, maternal and fetal
health outcomes
--
Timing Any --
Study Design … ; OUD = opioid use disorder; PICOTS = population, intervention, comparator,
outcome, timing, study design …
Inclusion/exclusion criteria
Sample size at recruitment and followup rates
Population
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
June 01, 2012 - The sample size of the randomized trials ranged from 82 11
to 806 7. … The sample size of the observational studies ranged from 40 13 to 149 5 participants. … The findings from an RCT with smaller sample size (n=82) favored the revascularization
group:
Medical … [sample size =55]
The survival curves were nearly
identical for the two groups over 42
months. … Or 2) a trial not published in the above top 5 journals but have a sample size of at least triple the