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121. BLUEPRINT FOR A FUTURE DISTRIBUTED RESEARCH NETWORK (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-blueprint_research.pdf
     June 01, 2010 - proof-of-principle implementation of a network prototype demonstrating some of the design features described … rationale, goals, potential uses, and challenges associated with a distributed research network have been described … Key Features of the Network The key features of the network are described below. … Query Distribution A “pull” mechanism (also described as publish-and-subscribe or polling) in which … Summary/Conclusions The blueprint described above presents a systematic approach to building the infrastructure

122. Rapid Evidence Product_Assisted Home Dialysis in the United States: New Interest in an Old Idea (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/home-dialysis-ESKD-rapid-research.pdf
     April 01, 2025 - They described different levels of assistance, with some patients requiring minimal help and others … Additionally, an older Canadian study described their experience with a respite care program for home … As described above, the Satellite Healthcare pilot assisted PD program focused on temporary assistance … Canada In the multicenter study in British Columbia described above, the investigators compared outcomes … Patients were allowed 2 weeks/year of relief dialysis. 3 months training (not described) Respite

123. Disposition of Comments for Screening of Methicillin-Resistant Staphylococcus Aureus (MRSA) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_disposition-comments.pdf
     January 01, 2010 - The definitions and ratings criteria are very well described. … How is this question different from what was described for Questions 3a/b/c? … are described as “SS ↓”? … We have reviewed these guidelines to ensure they have been described accurately. … These have been described in the preceding comments.

124. Disposition of Comments_Systematic Review: Mental Health and Occupational Stress in the Emergency Medical Services and 911 Workforce (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-disposition-comments.pdf
     February 28, 2025 - In addition, mental health-related issues are described for EMS clinicians but again, not similarly … described for telecommunicators. … not deterred from future research on EMS workers. 22 Peer Reviewer #3 Methods Based on the methods described … The limitations are clearly described.

125. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
     September 25, 2013 - The mechanisms underlying the use of phenotypic tests for platelet reactivity are described in detail … However, the study results have not been published and were not included in the analysis described in … We recognize that a cutoff date for including studies in the analysis described in the draft report … As described above, there are significant fundamental differences between the test methods evaluated … Both of these points are described in more detail above.

126. DEcIDE 34 - Developing a Registry of Patient Registries: Options for the Agency for Healthcare Research and Quality (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/registry-of-patient-registries-development_research_0.pdf
     February 01, 2012 - , and only 7,000 are described as prospective observational studies. … As described further below, these actions have successfully led to large increases in the listing of … Clinicaltrials.gov provides an excellent model for the study-listing component described in Table 1. … As described earlier, there would be incremental gain in each additional function supported by such … These requirements are described in detail in Table 1.

127. Disposition of Comments for CER 196 The Role of Immunotherapy in the Treatment of Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-196-disposition-comments-immunotherapy-asthma.pdf
     March 23, 2018 - The PICOTS framework and the attribution of specific measures to each area are well described. … The statistical methods are well described and appropriate. … The characteristics of the studies are clearly described. The tables contain good detail. … Limitations are appropriately described, as is the Future Research section. … Characteristics of the studies are clearly described in the text and table 2.

128. Slide 1
     effectivehealthcare.ahrq.gov/sites/default/files/sensitivity-analysis-chapter-11.pptx
     January 01, 2013 - software-based Statistical software-based approaches can be helpful where the association is not well described … The presentation proposed and described planned sensitivity analyses, described important subpopulations … in which measures of effect will be assessed for homogeneity, described modeling assumptions and how

129. Disposition of Comments Report for The Patient-Centered Medical Home (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_disposition-comments.pdf
     July 03, 2012 - Key questions are well-defined and described. Thank you for the comment. … Peer Reviewer 3 Results Overall, the level of detail is appropriate, studies are clearly described, … Study characteristics are clearly described. … SOE was defined as described in the Methods (see Strength of Body of Evidence). … Instead, studies focus on the process of care, as described by the reviewer.

130. Methods-Guidance-Reporting-Bias Methods (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
     November 01, 2013 - As a third example, given the fact that only 60 percent of randomized controlled trials (RCTs) described … Background Definitions and History The Institute of Medicine has recently described reporting bias … For abstracts that were clearly described, primary endpoints were identical in 90 percent of cases; … Alternatively, EPCs could also construct a matrix as described by Kirkham et al.23 and illustrated by … Reporting the Search Strategy and Results General Guidelines As described more fully in the chapter

131. Disposition of Comments_Comparative Effectiveness Review No. 274: Diagnosis and Treatment of Tethered Spinal Cord (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-274-tethered-spinal-cord-disposition-comments.pdf
     October 25, 2024 - There are still limited studies on the subgroups of tethered cord patients that a reviewer described … We checked and we could not find this text Public Reviewer 1 Methods The methods are clearly described

132. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-postpartum-screening_research-protocol.pdf
     May 01, 2013 - instruments, health-related quality of life, and health-system resource utilization (measured as described … Data necessary for assessing quality and applicability, as described in the Methods Guides, will also … The strength of evidence will be assessed by using the approach described in the Methods Guides.30,31,38 … Assessing Applicability We will assess applicability across our KQs using the method described in … The strength of evidence will be assessed by using the approach described in the Methods Guides.30,31,38

133. Medical-Evidence-Communication Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-evidence-communication_research-protocol.pdf
     July 31, 2012 - nurses, midlevel providers, and/or pharmacists Interventions Specific clinical interventions are described … Comparators Alternate presentations of the specified interventions Outcomes Specific outcomes are described … As described above, evidence dissemination has several broad goals. … The steps that we will take to accomplish the literature review are described below. … review each full-text article for inclusion or exclusion on the basis of the eligibility criteria described

134. Comparative Effectiveness Review Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/bundled-payments-quality-effects_disposition-comments.pdf
     August 24, 2012 - should note in the Executive Summary, that many of the interventions themselves are incompletely described … added the following sentence to the abstract: “The interventions studied were often incompletely described … But these programs are not described. … The effect described sounds like regression to the mean rather than an intervention effect. … Items described above: Items 1 through 3 above suggest obvious additional areas of research.

135. Disposition of Comments for Technical Brief 28 MAT Models (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-use-disorder_disposition-comments.pdf
     December 06, 2016 - The need to evaluate prescribing of buprenorphine by non- physician providers is described as a future … Pharmacy-based models are described in the New and Innovative Strategies section and research in this … In addition, as described in the Brief, pharmacists are partnering with physicians to provide MAT.9 … Misstated information-it turns out that the Hub and Spoke model does NOT function as described. … The mortality associated with opioid use disorder is described earlier in this section.

136. The Refinement of Topics for Systematic Reviews: Lessons and Recommendations From the Effective Health Care Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-refinement_methods.pdf
     January 01, 2013 - Our work group followed previously described basic principles for developing methods guidance in the … EPC program.9 As a first step, work group members each described their own EPC’s approach to topic … The AHRQ Project Officer then described successful and unsuccessful procedures used by other EPCs not … described public accountability as an ethical requirement for topic identification and selection in … These changes have been incorporated into an updated document (Appendix A) and are described in the

137. Psychosocial and Pharmacologic Interventions for Disruptive Behavior in Children and Adolescents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-protocol.pdf
     January 31, 2023 - Criteria for Inclusion/Exclusion of Studies in the Review: We will use the inclusion/exclusion criteria described … Effectiveness Reviews.18 Studies will be rated as being “low,” “moderate,” or “high” risk of bias as described … initially assessed by one researcher for each clinical outcome (see PICOTS) by using the approach described … The strength of the evidence may be downgraded based on the limitations described above. … existence of plausible unmeasured confounders), if there are no downgrades on the primary domains, as described

138. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tethered-spinal-cord-protocol.pdf
     July 19, 2023 - On the other hand, spinal column shortening to decrease spinal cord tension has been described and utilized … Discussions with the TEP also informed pre-planned subgroup analyses described in the data synthesis … Following the described input, the final key questions are as follows: Key Question 1: What is the … Data necessary for assessing quality and applicability as described in the EPC Methods Guide will also … The strength of the evidence may be downgraded based on the limitations described above.

139. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-health-children_research-protocol.pdf
     December 11, 2015 - , skills building); and (4) strategies that use a multipronged approach with any of the previously described … The appropriateness of those studies will be determined using the methods described above. … As described above, all results will be tracked in an EndNote database. … For systematic reviews, we will use the five-step process described in the AHRQ Methods Guide37 to assess … This information will contextualize the published data and inform additional analysis described

140. Disposition of Comments for Use of Natriuretic Peptide Measurement in the Management of Heart Failure (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
     November 20, 2013 - The Methods are well described in the text of the report. … Corrected in report Rev 3 results Page 249 – several of the studies are described as a RCTs. … We used the definition of HF as described by each author for his/her study. … The clinical context has been described as recommended in current clinical practice guidelines. … The algorithms for use of NP in practice are described in both the Canadian and European guideline.