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effectivehealthcare.ahrq.gov/sites/default/files/pdf/harmonization-depression-draft-report.pdf
March 15, 2021 - 15-19)
- Severe depression (20+)
Yes 1 Yes 3
Duration of
symptoms
Duration of depressive symptoms … PsychPRO:
Difficulty
Level
Worsening in
depressive
symptoms –
recurrence at 6
months
Whether … Clinical
Response
Improvement in
Depressive
Symptoms—
Response
Patients aged 18 or older with … Clinical
Response
Improvement in
Depressive
Symptoms—
Remission
Patients aged 18 or older with … xx (xx.x%)
xx (xx.x%)
Improvement in depressive symptoms --
response at 6 months
Yes
No
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effectivehealthcare.ahrq.gov/products/depression-postpartum-screening/research-protocol
March 09, 2012 - The impact of depression in postpartum women is at least as great as that for depression in other populations … Women with current depression or a history of major depression warrant particularly close monitoring … Depression Scale (Zung SDS)
Hamilton Rating Scale for Depression (HRSD)
Postpartum Depression Predictors … Maternal depressive symptoms at 2 to 4 months post partum and early parenting practices. … Obstetric, somatic, and demographic risk factors for postpartum depressive symptoms.
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effectivehealthcare.ahrq.gov/products/depression-brain-injury/research-protocol
December 09, 2009 - Outcomes
Depressive symptom status
Harms
Need for additional treatment
Change in quality of … life
Activities of daily living
Recurrence of depression
Timing
Depression must occur after … #2
mental disease/ or mood disorder/ or depression/ or major depression/ or suicidal ideation/ or … Depression and anxiety following traumatic brain injury. … Head injury in early adulthood and the lifetime risk of depression.
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effectivehealthcare.ahrq.gov/products/depression-brain-injury/research
April 13, 2011 - Protocol Apr. 13, 2011 Systematic Review Sep. 2, 2016 Surveillance Report Traumatic Brain Injury and Depression … Results
The prevalence of depression after traumatic brain injury (TBI) was approximately 30 percent … appropriately identify individuals with depression after a TBI. … No evidence is available to guide treatment choices for depression after head injury. … Overall the evidence is low to guide screening and care for depression after TBI.
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effectivehealthcare.ahrq.gov/products/depression-brain-injury
December 09, 2009 - Traumatic Brain Injury and Depression
Timeline
January 01, 2005
Topic Initiated … December 09, 2009
Research Protocol
Archived
Traumatic Brain Injury and Depression … April 13, 2011
Systematic Review
Archived
Traumatic Brain Injury and Depression
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effectivehealthcare.ahrq.gov/products/treatment-resistant-depression/research
September 23, 2011 - Comments Report May. 3, 2016 Surveillance Report Nonpharmacologic Interventions for Treatment-Resistant Depression … effectiveness of four nonpharmacologic treatments as therapies for patients with treatment-resistant depression
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effectivehealthcare.ahrq.gov/products/depression-pregnancy-postpartum/research
July 08, 2014 - 8, 2014 Systematic Review Nov. 3, 2014 Disposition of Comments Report Antidepressant Treatment of Depression … Review methods
We included studies comparing pharmacological treatments for depression during or after … For postpartum women with depression, evidence was insufficient to evaluate the full range of benefits … These are major limitations, as depression is known to be associated with serious adverse outcomes. … Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period.
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effectivehealthcare.ahrq.gov/products/mental-health-pregnancy/research
April 15, 2021 - Brexanolone probably improves depressive symptoms; it may increase the risk of sedation or somnolence … Sertraline may improve response, remission, and depression and anxiety symptoms. … depressive symptoms at 30 days (least square mean difference in the Hamilton Rating Scale for Depression … interval [CI], 0.95 to 5.24; N=36), remission (calculated RR, 2.51; 95% CI, 0.94 to 6.70; N=36), and depressive … symptoms (p-values ranging from 0.01 to 0.05) when compared with placebo.
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effectivehealthcare.ahrq.gov/products/treatment-resistant-depression
December 09, 2009 - Nonpharmacologic Interventions for Treatment-Resistant Depression in Adults
Timeline … Research Protocol
Archived
Non-Pharmacologic Interventions for Treatment-resistant Depression … Systematic Review
Archived
Nonpharmacologic Interventions for Treatment-Resistant Depression
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effectivehealthcare.ahrq.gov/products/depression-knowledge-gaps
January 01, 2005 - Addressing Knowledge Gaps in the Treatment of Depression
Timeline
January 01, 2005 … January 01, 2005
Research Report
Addressing Knowledge Gaps in the Treatment of Depression
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effectivehealthcare.ahrq.gov/products/antidepressants-update/research-protocol
July 13, 2011 - symptoms? … to one agent in the past, is that agent better than current pharmacologic alternatives at treating depressive … symptoms? … absence of depressive symptoms for an additional 4 to 9 months, such that the patient’s episode can … Relapse: return of depressive symptoms during the acute or continuation phases, it is considered part
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effectivehealthcare.ahrq.gov/products/childhood-depression
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effectivehealthcare.ahrq.gov/sites/default/files/nt_docs/1002-nonpharmacologic-treatment-topic-brief.pdf
August 01, 2022 - Vital Signs: Postpartum Depressive Symptoms and Provider
Discussions About Perinatal Depression - United … Digitalized Cognitive Behavioral
Interventions for Depressive Symptoms During Pregnancy: Systematic … Mhealth mindfulness intervention for women with
moderate-to-moderately-severe antenatal depressive symptoms … Group-based multicomponent
treatment to reduce depressive symptoms in women with co-morbid psychiatric … Internet-based behavioural activation to improve
depressive symptoms and prevent child abuse in postnatal
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effectivehealthcare.ahrq.gov/products/library-depression/white-paper
May 12, 2020 - Standardized Library of Depression Outcome Measures
White Paper May 12, 2020 Download Main Document … This document describes the technical approach used to prepare the Standardized Library of Depression … For reference, the narrative definitions for the minimum set of outcome measures produced by the Depression … Harmonized outcome measures for use in depression patient registries and clinical practice . … Standardized Library of Depression Outcome Measures. Research White Paper.
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effectivehealthcare.ahrq.gov/products/depression-pregnancy-postpartum/
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effectivehealthcare.ahrq.gov/products/depression-treatment-ssri/
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effectivehealthcare.ahrq.gov/products/depression-postpartum-screening/
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-childhood-protocol.pdf
August 06, 2018 - in
depressive symptoms, remission (typically defined as a continuous measure of depression
decreasing … symptoms in these young patients, reduce their risk of developing other mood
disorders, strengthen … symptoms
• Suicidality
• Mortality
• Functional impairment
(KQs 1a, 2a, 3a, 4a, 5a)
(KQs 1a, 2a, 3a … symptoms, suicidality, mortality, and functional
impairment). … symptoms
Suicidality
Mortality
Functional impairment
Harms:
Any AEs of intervention (e.g., death
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0367_11-08-2010.pdf
January 01, 2010 - Outcome(s): Effectiveness of screening approaches, safety and efficacy of treatment,
improvements in depressive … symptoms, parenting skills, and quality of life
Key Questions
from Nominator:
1. … )
Postpartum depression affects many women the first year after birth. … In addition to the adverse effects
of depression on mothers and their quality of life, postpartum depression … review will be broadened to screening and treatment of
perinatal depression.
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effectivehealthcare.ahrq.gov/products/depression-treatment-ssri/research-protocol
June 15, 2010 - Persons with post-partum depression, bipolar depression, depressive psychosis, dysphoria, mourning syndrome … , postoperative depression, premenstrual dysphoric disorder, pseudodementia, puerperal depression, seasonal … , bipolar depression, depressive psychosis, dysphoria, mourning syndrome, postoperative depression, premenstrual … Augmentation strategies for treatment-resistant depression: a literature review. … Treatment resistant depression: methodological overview and operational criteria.