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21. Depression | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/depression?page=1

22. Depression | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/depression?page=2

23. Traumatic Brain Injury and Depression (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury_executive.pdf
    April 01, 2011 - Traumatic Brain Injury and Depression Introduction We do not know the extent to which depression contributes … Importance of Depression Depression is defined by criteria that likely circumscribe a heterogeneous … The second study128 investigated the effect of citalopram on depressive symptoms after TBI, using an … Risk factors for depressive symptoms after mild-to-moderate traumatic brain injury. … Attention and depressive symptoms in chronic phase after traumatic brain injury.

24. Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
    July 01, 2014 - or depressive symptoms (gaps in the evidence). … Maternal Benefits Comparative evidence on depressive symptom response, anxiety, functional capacity, … symptoms Insufficient; no conclusions drawn SSRIs: fluoxetine No treatment Depressive symptoms Insufficient … therapy Depressive symptoms. … Cross-cultural and social diversity of prevalence of postpartum depression and depressive symptoms.

25. Diagnostic Accuracy of Screening and Treatment of Post–Acute Coronary Syndrome Depression: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/acs-depression/research-review-final
    November 14, 2017 - Available depression-screening tools may miss 3 percent of people with depression, but less than 50 percent … of those who screen positive have clinically confirmed depression.  … depressive symptoms using a validated depression scale and who are within 3 months of an ACS event. … Among several depression screening tools, the BDI is the most studied. … who screen positive actually have clinically confirmed depression.

26. Non-Pharmacologic Interventions for Treatment-resistant Depression in Adults — Research Protocol Document | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/treatment-resistant-depression/research-protocol
    December 09, 2009 - The FDA approved VNS and rTMS for use in depression in 2005 and 2008, respectively. … (e.g., cognitive therapy [CBT or IPT]) differ in efficacy or effectiveness in treating acute phase depressive … symptoms (e.g., response and remission), whether as a single treatment or part of a combination treatment … treatments compare with pharmacological treatments in efficacy or effectiveness in treating acute phase depressive … symptoms after two or more failed adequate trials?

27. Outcome Measure Harmonization and Data Infrastructure for Patient-Centered Outcomes Research in Depression | Effective Health Care Program
    effectivehealthcare.ahrq.gov/products/pcor-depression
    March 30, 2021 - Outcome Measure Harmonization and Data Infrastructure for Patient-Centered Outcomes Research in Depression

28. Standardized Library of Depression Outcome Measures | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/library-depression
    May 12, 2020 - Standardized Library of Depression Outcome Measures Timeline February 12, 2019 Topic … Initiated May 12, 2020 White Paper Standardized Library of Depression

29. Depression-Pregnancy-Postpartum Research (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research.pdf

30. Treatment of Depression in Children and Adolescents: A Systematic Review - Evidence Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_0.pdf
    April 01, 2020 - TAU/UC 12-16 weeks Depressive symptoms, clinician- reported Mean difference (CDRS): 7.11; … wait-list 8 weeks Depressive symptoms, clinician report Mean difference (CDRS-R), -13.99; 95% … CBT also resulted in greater improvements in depressive symptoms among those with comorbid ADHD. … placebo 12 weeks       Depressive symptoms, clinician report Mean difference (CDRS-R): 7.98; … placebo 12 weeks       Depressive symptoms, clinician report Mean difference (CDRS-R): 7.98;

31. Treatment of Depression in Children and Adolescents: A Systematic Review - Evidence Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/Evidence%20Summary_0_0.pdf
    April 01, 2020 - TAU/UC 12-16 weeks Depressive symptoms, clinician- reported Mean difference (CDRS): 7.11; … wait-list 8 weeks Depressive symptoms, clinician report Mean difference (CDRS-R), -13.99; 95% … CBT also resulted in greater improvements in depressive symptoms among those with comorbid ADHD. … placebo 12 weeks       Depressive symptoms, clinician report Mean difference (CDRS-R): 7.98; … placebo 12 weeks       Depressive symptoms, clinician report Mean difference (CDRS-R): 7.98;

32. Executive Summary_Comparative Effectiveness Review No. 271: Nonpharmacologic Treatments for Maternal Mental Health Conditions (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-271-mental-health-pregnant-executive-summary.pdf
    July 01, 2024 - rates of remission for depressive symptoms (low SoE). … SoE) and anxiety symptoms (low SoE), and may increase remission rates for depressive symptoms (low … o Behavioral activation may be more effective than TAU to reduce depressive symptoms (low SoE). … o Exercise interventions are probably more effective than TAU to reduce depressive symptoms (moderate … the Edinburgh Postnatal Depression Scale (EPDS).

33. Depression in Children: Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/childhood-depression/protocol
    August 24, 2018 - in depressive symptoms, remission (typically defined as a continuous measure of depression decreasing … For example, better information on PDD treatment might help clinicians resolve depressive symptoms in … symptoms, suicidality, mortality, and functional impairment). … All other comparators Outcomes **** Benefits: Remission Response Relapse Depressive … symptoms Suicidality Mortality Functional impairment Harms: Any AEs of intervention

34. Adverse Effects of First-line Pharmacologic Treatments of Major Depression in Older Adults | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/depression-harms/research-protocol
    February 07, 2018 - Background and Objectives for the Systematic Review Depression is a common psychiatric disease in older … Approximately 15–20 percent of adults older than age 65 in the United States have experienced depression … While the effectiveness of interventions for treatment of depression in the elderly has been previously … improvement on either the HAM-D or MADRS scales Remission: commonly defined as absence or near absence of depressive … symptoms, or a HAM-D score of <8.

35. Harms of First-Line Depression Treatment in Older Adults | Effective Health Care Program
    effectivehealthcare.ahrq.gov/products/depression-harms
    February 07, 2018 - Harms of First-Line Depression Treatment in Older Adults Timeline July 20, 2017 Topic … Research Protocol Adverse Effects of First-line Pharmacologic Treatments of Major Depression … Systematic Review Adverse Effects of Pharmacological Treatments of Major Depression

36. Identification and Treatment of Post-Acute Coronary Syndrome (ACS) Depression: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/acs-depression
    August 31, 2016 - Identification and Treatment of Post-Acute Coronary Syndrome (ACS) Depression: A Systematic Review … Research Protocol Identification and Treatment of Post-Acute Coronary Syndrome (ACS) Depression … Review Diagnostic Accuracy of Screening and Treatment of Post–Acute Coronary Syndrome Depression

37. Identification and Treatment of Post-Acute Coronary Syndrome (ACS) Depression: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/acs-depression/research-protocol
    August 31, 2016 - general population with depression to commonly used, efficacious treatments for depression. … outcomes Response or remission of depressive symptoms using validated continuous or categorical measures … outcomes Response or remission of depressive symptoms using validated continuous or categorical measures … For depressive symptoms and QOL, it is likely that studies will use different instruments to measure … or had clinically important depressive symptoms using a validated depression scale, and are within 3

38. Research White Paper: Standardized Library of Depression Outcome Measures (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/standardized-library-depression-white-paper.pdf
    May 01, 2020 - Of note, several outcome measures focus on change over time, such as improvement in depressive symptoms … Clinical Response Improvement in Depressive Symptoms – Remission Patient age 18 or older with a … A-2 OMF CATEGORY OUTCOME MEASURE DEFINITION Clinical Response Improvement in Depressive Symptoms … A-3 OMF CATEGORY OUTCOME MEASURE DEFINITION Clinical Response Worsening in Depressive Symptoms – … Patient Reported Depression-specific Quality of Life Depression-specific quality of life should be measured

39. Research White Paper: Standardized Library of Depression Outcome Measures (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/standardized-library-depression-white-paper.pdf
    May 01, 2020 - Of note, several outcome measures focus on change over time, such as improvement in depressive symptoms … Clinical Response Improvement in Depressive Symptoms – Remission Patient age 18 or older with a … A-2 OMF CATEGORY OUTCOME MEASURE DEFINITION Clinical Response Improvement in Depressive Symptoms … A-3 OMF CATEGORY OUTCOME MEASURE DEFINITION Clinical Response Worsening in Depressive Symptoms – … Patient Reported Depression-specific Quality of Life Depression-specific quality of life should be measured

40. Disposition of Comments for Diagnostic Accuracy of Screening and Treatment of Post-Acute Coronary Syndrome Depression (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-200-comments-post-acs.pdf
    November 14, 2017 - Some published studies used elevated depressive symptoms rather than depression diagnosis as eligibility … We agree that subthreshold depressive symptoms can be important. … who had clinically important depressive symptoms using a validated depression scale. … Peer Reviewer #2 Results The description of the efficacy of depression treatments on depressive symptoms … symptoms in first week after ACS versus targeting patients with persistently elevated depressive symptoms