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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0024_06-09-2008.pdf
    January 01, 2008 - patients with schizophrenia, related psychoses (including first episode), bipolar mania or bipolar depression
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/bimp-protocol.pdf
    September 27, 2022 - benefits and harms of non-headache focused behavioral interventions (e.g., CBT for insomnia, CBT for depression … symptoms (e.g., PHQ4, PHQ 9, CDI, PROMIS Pediatric-Depression, HADS) Other: • Most bothersome symptoms … Additional outcomes: • Anxiety (e.g., GAD-7, PROMIS Pediatric - Anxiety) • Depression (e.g., PHQ … 4, PHQ 9, CDI, PROMIS Pediatric-Depression) • Sleep outcomes (sleep onset latency, wake after sleep … Form, FIS = Fatigue Impact Scale, GAD-7 = General Anxiety Disorder-7, HADS = Hospital Anxiety and Depression
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
    May 29, 2025 - central, due to MS) THC/CBD spray 14 Short 14 167 2 167 34 167 167 13 167 167 16 167 167 12 167 167 Depression … Good NPC (central, due to MS) Placebo 14 Short 9 172 1 172 7 172 172 7 172 172 3 172 172 10 172 172 Depression
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement-may-2025.pdf
    January 01, 2025 - psychological functioning after receiving an intervention targeting suicidal behaviors and thoughts (e.g., depression … Remission and recovery in the Treatment for Adolescents with Depression Study (TADS): acute and long-term … Escitalopram in the treatment of adolescent depression: a randomized placebo-controlled multisite trial … Effectiveness of a quality improvement intervention for adolescent depression in primary care clinics
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-repository-expanded-protocol.pdf
    October 24, 2019 - placebo • Outcomes: o Overall PTSD outcome, PTSD Diagnostic Change o Other outcomes – Anxiety, anger, depression … with health and functional outcomes including PTSD symptoms and diagnosis, substance use, anxiety, depression … Final health outcomes • Overall PTSD assessment • PTSD diagnostic change • Anger • Anxiety • Depression … Census categories) m. % Treatment-naïve n. % with depression o. % with substance use disorder p. … Between-group effect sizes for all reported depression outcomes m.
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-executive-summary.pdf
    December 01, 2022 - may provide benefits for inpatient care, for neonates in rural hospitals, outpatient management of depression … with diabetes:  Some improvement in medication adherence and treatment response for patients with depression … o For patients with depression:  Higher utilization of telehealth and corresponding costs for outpatient … consultations for depression are associated with increased access and cost-effectiveness analyses
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
    November 02, 2018 - and quality of life vary as a function of patient characteristics (i.e., age, sex, race/ethnicity, depression … For all key questions, we will examine age, sex, race/ethnicity, depression, and pretreatment cognitive … Added depression as possible effect modifier. … Depression may be important in interpreting results of treatment and diagnostic studies. … , anxiety, QOL, injury Caregiver harms for BPSD drug treatments changed to depression, QOL, global
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-draft-protocol.pdf
    March 14, 2024 - psychological functioning after receiving an intervention targeting suicidal behaviors and thoughts (e.g., depression … Remission and recovery in the Treatment for Adolescents with Depression Study (TADS): acute and long-term … Escitalopram in the treatment of adolescent depression: a randomized placebo-controlled multisite trial … Effectiveness of a quality improvement intervention for adolescent depression in primary care clinics
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_disposition-comments.pdf
    January 26, 2015 - The use of depression and anxiety as the primary variables in the categorization of mental health should … Depression and anxiety were separately reported in several studies (Appendix Tables E4-E7 of the report … On the other hand, there are modifiable variables that can subgroup patients, such as depression and … We edited the statement in the Discussion to, For depression,…. … Efficacy and Safety of Pregabalin in Patients with Fibromyalgia and Co-Morbid Depression Receiving
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
    August 01, 2012 - (HAM–D), Montgomery-Asberg Depression Rating Scale (MADRS), and Young Mania Rating Scale (YMRS). … Mood (depression) Haloperidol vs. aripiprazole Low No significant difference in MADRS (2 RCTs). … ; KQ = Key Question; MADRS = Montgomery-Asberg Depression Rating Scale; PANSS = Positive and Negative … included in this report) with FGAs for overall efficacy (total symptom scores); positive, negative, and depressivesymptoms; relapse; quality of life; EPS; weight gain; and sedation.
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
    February 01, 2012 - However, SGAs did not differ from placebo for depression symptoms in this group (low SOE). … • PDDs: ADHD, anxiety disorders • ADHD and DBDs: Substance abuse, depression, anxiety disorders … abuse • Anorexia nervosa/bulimia nervosa/eating disorder NOS: Depression • Tourette syndrome: ADHD … Outcomes include aggression, depression, social/occupational functioning, health related quality of … antipsychotics is low or insufficient for other clinically meaningful outcomes such as: aggression, depressions
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0365_10-28-2010.pdf
    January 01, 2010 - index.cfm/join-the-email-list1/ Topic Number: 0307 Document Completion Date: 02-25-11 2 (depressivesymptoms, anxiety symptoms, suicidal ideation/plans/attempts, substance use); remission (no longer
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_consumer.pdf
    May 01, 2016 - obesity � Digestive problems � Headaches � Joint pain � Muscle pain � Stress � Trouble sleeping � Depression … Yes Have fewer symptoms of depression? … Second-generation antidepressants �� These medicines were made to treat depression, but they are also
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pwd-care-interventions-protocol.pdf
    February 22, 2019 - Expenditures/financial burden (informal caregivers) Health-related outcomes: Psychological health (e.g., depression … patient or informant Alexopoulos et al. 1988 Patient Health Questionnaire (PHQ-9) Depression patient … Spitzer et al., 1999 Geriatric Depression Scale (GDS) 30-item Depression patient Yesavage et al. 1983 … Geriatric Depression Scale (GDS) 15-item Depression patient Montgomery Asberg Depression Rating Scale … (MADRS) Depression Montgomery & Asberg, 1979 Hamilton Depression Rating Scale (HDRS) Depression
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-3.xlsx
    September 30, 2015 - B Mean age: 53.9 vs. 50.7 Female sex: 80% vs. 53.3% White race: 33.3% vs. 86.6% Depression: 40% vs. 66.6% … with emotional problems): adjusted odds ratio 0.69, p=0.16 (treatment x time, adjusted for race and depression … , p<0.001 Mental health crises: 3117/22097 vs. 8258/152194; aIRR 2.28, 95% CI 1.96 to 2.65, p<0.001 Depression … heart disease, congestive heart failure, acute ischemic stroke, and intracranial hemorrhage), major depression … , health insurance and prescription drug coverage), geographic region, need factors (comorbidities, depression
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-youth-disposition-comments.pdf
    April 10, 2025 - This section reports the current treatment guidelines and that they are based on depression trials … One could argue there are other risk factors like depression. … , “We did not include studies on comorbid conditions such as depression in which suicide might co … Given the robust effect for depression, it is an important area of future research. … Influence of aerobic exercise on depression in young people: a meta- analysis.
  17. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/ems-911-workforce-topic-development-brief.pdf
    February 01, 2022 - or behavioral health issues, including post-traumatic stress disorder (PTSD) (11%), anxiety (15%), depression … Incidence, prevalence, and severity of mental health issues (depression, anxiety, PTSD, suicidality … A prospective study of predictors of depression symptoms in police. … An assessment of depression, anxiety, and stress among nationally certified EMS professionals. … ) OR AB (Depression) OR (mh depression) 18 TI (Anxiety) OR AB (Anxiety) OR ((mh ^anxiety) OR (mh catastrophization
  18. effectivehealthcare.ahrq.gov/products/antidepressants-2007/research
  19. effectivehealthcare.ahrq.gov/sites/default/files/09_infectiousdisease_potential_high_impact_june_2012.pdf
    January 01, 2012 - Overall High Impact Potential: Collaborative care model for HIV and depression .......... 8 Figure … (without HIV comorbid), depression and diabetes, and depression and cancer. … HIV translating initiatives for depression into effective solutions (HI-TIDES). … Effectiveness of collaborative care for depression in human immunodeficiency virus clinics. … Depression and HIV [NIH publication no. 02- 5005].
  20. effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
    January 01, 2018 - The effects for depression symptoms or global impressions of improvement are not known. … They may make little or no difference in depression symptoms. … Compared with placebo, SGAs likely reduce manic symptoms and probably decrease slightly depression … Quetiapine probably reduces manic symptoms, likely makes little or no difference for depression symptoms … The effect on depressive symptoms may be small and possibly nonsignificant for schizophrenia and bipolar

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