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101. Management of Insomnia Disorder in Adults: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/insomnia_clinician.pdf
     August 01, 2017 - or suicidal thoughts in people with primary depression �� Severe anaphylactic or anaphylactoid reactions … �� Possible profound sedation, respiratory depression, coma, and death with concomitant opioid use … � Sleep paralysis, hypnagogic or hypnopompic hallucinations, cataplexy-like symptoms �� Worsening depression … or suicidal thoughts �� Possible respiratory depression in people with severe lung disease or sleep … or suicidal thoughts �� Possible respiratory depression in people with severe lung disease or sleep

102. Disposition of Comments for CER 208 Treatment for Bipolar Disorder in Adults A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-adults-disposition-comments.pdf
     August 07, 2018 - First-generation antipsychotics (and possibly risperidone) can increase the risk of depression. … Response of depression to electroconvulsive therapy: A meta-analysis of clinical predictors. … We have moved the study to the depression chapter. … Efficacy of tranylcypromine in bipolar depression: A systematic review. … Who will benefit from antidepressants in the acute treatment of bipolar depression?

103. Mental Health and Occupational Stress in the Emergency Medical Service and 911 Workforce: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-protocol-amendment.pdf
     January 22, 2024 - EMS clinicians have been shown to be at high risk for anxiety, depression, posttraumatic stress disorder … 2018 systematic review documented the following prevalence among first responders: anxiety (15%), depression … KQ1= What are the incidence, prevalence, and severity of mental health issues (depression, anxiety, PTSD … Frontline Healthcare Workers' Burnout, Anxiety, and Depression? Int J Environ Res Public Health. … depression[tiab] OR depressed[tiab] OR depression[mh] 556,916 14.

104. Dementia-Nursing-Home-Characteristics Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_executive.pdf
     October 01, 2012 - • Health outcomes for informal caregivers of people with dementia, such as depressive symptoms; sleep … In a second study, a lighting intervention produced better depressive symptoms outcomes for women … Low Depressive symptoms Depressive symptoms were better for women but worse for men after a bright morning … Low Structures of Care Morning bright light vs. all-day light/control Depression/depressive symptoms … • Continue studying outcomes of depressive symptoms, hospitalization, and quality of life, but also

105. Topic 0548 Comparative Effectiveness of Treatments for MDD NSD FINAL SJ (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0647-13114.pdf
     June 21, 2013 - Outcome(s): Improvement in symptoms of depression; reduced suicide risk; improved social and occupational

106. Evidence Report No. 222, Data Linkage Strategies To Advance Youth Suicide Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/suicide-prevention_research.pdf
     October 01, 2016 - Linear mixed effects regression model Curry, 201146 Family income, depressive symptoms, cognitive … distortions Family income, depressive symptoms, and cognitive distortions all moderated the acute … Depressive symptoms and clinical status during the Treatment of Adolescent Suicide Attempters (TASA … Depressive symptoms and clinical status during the Treatment of Adolescent Suicide Attempters (TASA) … Juvenile justice girls' depressive symptoms and suicidal ideation 9 years after Multidimensional Treatment

107. Cer-250-Cannabis-Table-E5-2022-Update 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-table-e5-2022-update_0.xlsx
     January 01, 2022 - C Hospital Anxiety and Depression Scale total score (mean [SD], scale unclear, at 6 months): 10.4 (6.4 … C Individual SF-36 domains; Individual depression and anxiety domains for HADS; BPI Pain Severity; EQ … B Beck Depression Inventory (mean [SD], 0 to 63 scale) 7.22 (9.4) vs. 12.00 (16.27), mean difference … B Depression (DASS-D; NRS21) mean relative change (improvement) rates at week 24 70.5% vs. 51.5%, p<0.001 … , Anxiety, Stress, Scale; HADS = hospital anxiety and depression scale; HIV = human immunodeficiency

108. Observed Association Between Antidepressant Use and Pneumonia Risk Was Confounded by Comorbidity Measures (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-seniors-pneumonia_research.pdf
     May 01, 2008 - as in the ninety-day period preceding a hospitalization for depression [7], leading to the hypothesis … in that it identified diagnoses occurring disproportionately after vs. before hospitalizations for depression … , and for complications of depression treatment. … Because of the large number of cases of hospitalization for depression, and the narrow CIs for this … ‡ Adjusted for age, sex, calendar year, number of non-depression GP visits in the prior six months,

109. Topic 0562 Treatments for Biploar Disorder NSD FINAL SJ (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0663-131114.pdf
     April 10, 2013 - somatic treatments (e.g., electroconvulsive therapy) in specific types of bipolar episodes (e.g., mania, depression … )  Bipolar disorder is characterized by recurrent episodes of mania and depression, which generally

110. App-F1-Surv-Report-2-Nonopioid-Pharmacol-Chronic-Pain (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
     May 29, 2025 - Depression outcomes for neuropathic pain Author, Year Quality Pain Population Drug Class 1 Drug Class … Measure Name Measure Scale Assessment Time (Wk) Time Category Grp 1 Baseline N Grp 1 Baseline Mean Depression … Score Lower Limit Grp1 Change Score Upper Limit Grp2 Followup N3 Grp2 Mean Change From Baseline on Depression … Limit Grp1 Followup N4 Grp2 Followup N5 Between-Group Mean Change Type Between-Group Mean Change on Depression … Depression outcomes for fibromyalgia Author, Year Quality Pain Population Drug Class 1 Drug Class 2

111. Menopause Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
     March 01, 2015 - • Psychological symptoms: Depressive symptoms, anxiety, and mood disturbances may occur. … Depressive symptoms can range from a depressed mood to clinical depression. … symptoms, anxiety, or global psychological well-being. … An increased risk for depressive symptoms during the menopausal transition in the absence of prior depressive … (-0.50 to -0.12) High Global 14 Estrogen vs. placebo -0.26 (-0.40 to -0.13) High Depressive symptoms

112. Cannabis-App-F5-Table-Surveillance-Report-2 0 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f5-table-surveillance-report-2_0_0.xlsx
     May 29, 2025 - Variables Accounted for in Analyses Pain Outcomes Functional Outcomes Quality of Life Outcomes Anxiety and Depression … C Hospital Anxiety and Depression Scale total score (mean [SD], scale unclear, at 6 months): 10.4 (6.4 … (16/55) 6 months: 33% (16/49) vs. 39% (20/52) vs. 33% (18/55) Individual SF-36 domains; Individual depression … B Beck Depression Inventory (mean [SD], 0 to 63 scale) 7.22 (9.4) vs. 12.00 (16.27), mean difference … BPI = brief pain inventory; CBD = cannabidiol; CI = confidence interval; HADS = hospital anxiety and depression

113. Appendix-E-Table-E5 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix-E-Table-E5_0.xlsx
     May 29, 2025 - Variables Accounted for in Analyses Pain Outcomes Functional Outcomes Quality of Life Outcomes Anxiety and Depression … C Hospital Anxiety and Depression Scale total score (mean [SD], scale unclear, at 6 months): 10.4 (6.4 … (16/55) 6 months: 33% (16/49) vs. 39% (20/52) vs. 33% (18/55) Individual SF-36 domains; Individual depression … B Beck Depression Inventory (mean [SD], 0 to 63 scale) 7.22 (9.4) vs. 12.00 (16.27), mean difference … BPI = brief pain inventory; CBD = cannabidiol; CI = confidence interval; HADS = hospital anxiety and depression

114. Evidence Summary CER 208 Treatment For Bipolar Disorder In Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-evidence-summary.pdf
     August 01, 2018 - Recurrent episodes of mania and depression can cause serious impairments in functioning, such as erratic … • Depression treatment: Evidence was insufficient for drug treatments for depressive episodes in adults … Some drugs aim to reduce symptoms associated with acute manic or mixed mania/depression episodes, some … The publications comprised 67 unique drug studies for acute mania, seven drug studies for depression … All depression treatment studies included adults with BD-II, while two also included BD-I.

115. App-D-Surv-Report-1-Noninvasive-Nonpharma 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-1-noninvasive-nonpharma_0.xlsx
     January 01, 2021 - moderate to severe symptoms): HAD Depression: % n with score >10 % HAD Anxiety: % n with score >10 … Hospital Anxiety and Depression Scal (HADS) total score ranges from 0 to 42. … . 7.2 (5.9) vs. 7.3 (5.7) Patient Health Questionnaire 8 (PHQ-8) (range 0-24, higher=more frequent depressive … symptoms; MCID=3 points) Generalized Anxiety Disorder 7-item Scale (GAD-7) (range 0-21, higher=more … Inventory (BDI) (range 0-63, higher=worse depression) 3 months A vs.

116. App-D-Surv-Report-2-Noninvasive-Nonpharma (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-2-noninvasive-nonpharma.xlsx
     January 01, 2021 - moderate to severe symptoms): HAD Depression: % n with score >10 % HAD Anxiety: % n with score >10 … Hospital Anxiety and Depression Scal (HADS) total score ranges from 0 to 42. … . 7.2 (5.9) vs. 7.3 (5.7) Patient Health Questionnaire 8 (PHQ-8) (range 0-24, higher=more frequent depressive … symptoms; MCID=3 points) Generalized Anxiety Disorder 7-item Scale (GAD-7) (range 0-21, higher=more … Inventory (BDI) (range 0-63, higher=worse depression) 3 months A vs.

117. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0645-151012.pdf
     August 05, 2015 - interventions with youth that have comorbidities including attention deficit hyperactivity disorder (ADHD), depression … Subgroups of interest include youth with comorbidities (e.g., ADHD, depression, somatic medical conditions … the comparative effectiveness of interventions with youth who have comorbidities, including ADHD, depression

118. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/analytic-frameworks.ppt
     December 09, 2009 - Systematic review protocol: traumatic brain injury and depression. … Available at: https://effectivehealthcare.ahrq.gov/products/depression-brain-injury/research-protocol … Systematic review protocol: traumatic brain injury and depression. … Available at: https://effectivehealthcare.ahrq.gov/products/depression-brain-injury/research-protocol … Systematic review protocol: traumatic brain injury and depression.

119. Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacological Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-236-maternal-fetal-child-outcomes-disposition-comments.pdf
     April 15, 2021 - The text now says “In addition to the negative effects on women’s health and well-being, depressive … symptoms are associated with adverse parenting practices such as reduced use of safety (such as always … Depression in Children and SSRIs. … time of onset, whereas the studies seem to have examined the effect of sertraline on response to depressive … symptoms in patients with different times of depression onset post- partum.

120. AHRQ's Evidence-based Practice Center Division Annual Report 2019: Solving the Puzzle for Evidence-Based Decision Making (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2019.pdf
     January 01, 2019 - Improve the Health of Older Adults: A Rapid Review Adverse Effects of Pharmacologic Treatments of Major Depression … effectivehealthcare.ahrq.gov/products/social-isolation/rapid-product https://effectivehealthcare.ahrq.gov/products/depression-harms … Tonsillectomy for Obstructive Sleep-Disordered Breathing or Recurrent Throat Infection in Children (2017) Depression … from the AAFP (AAFP) Diagnostic Accuracy of Screening and Treatment of Post– Acute Coronary Syndrome Depression