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1. #05 DEPRESSION (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1406.pdf
   June 01, 2014 - symptoms compared with patients receiving traditional in- person therapy sessions. … symptoms and suicidal ideations within 40 minutes compared with placebo. … symptoms were randomly assigned to complete SPARX or standard in-person behavioral therapy. … Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on … Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT- resistant major

2. #05 DEPRESSION (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1412.pdf
   December 01, 2014 - symptoms compared with symptoms of patients receiving traditional in-person therapy sessions. … symptoms and suicidal ideations within 40 minutes compared with placebo. … , potentially restoring normal emotional processing and easing depressive symptoms.69 Clinical data … Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on … Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT- resistant major

3. #05 DEPRESSION (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1506.pdf
   June 01, 2015 - For many patients, single ketamine doses often reduce depressive symptoms within 2 hours, with improvements … symptoms within a few hours or days, exponentially faster than many approved antidepressants.12,13 … symptoms and suicidal ideation within 40 minutes compared with placebo. … Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on … Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT-resistant major

4. #05 DEPRESSION (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1306.pdf
   October 01, 2014 - believe that dysfunction in glutamate neurotransmission may play a major role in the etiology of depressive … symptoms in both bipolar disorder and MDD, although its exact mechanism of action is still unknown … symptoms improved both significantly and rapidly and that these effects lasted from 3 days to several … Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on … Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT- resistant major

5. #05 DEPRESSION (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_2012-12-10.pdf
   January 01, 2012 - believe that dysfunction in glutamate neurotransmission may play a major role in the etiology of depressive … symptoms in both bipolar disorder and MDD, although its exact mechanism of action is still unknown … symptoms improved both significantly and rapidly and that these effects lasted from 3 days to several … Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on … Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT- resistant major

6. #05 DEPRESSION (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_june_2012.pdf
   January 01, 2012 - believe that dysfunction in glutamate neurotransmission may play a major role in the etiology of depressive … symptoms in both bipolar disorder and MDD, although its exact mechanism of action is still unknown … symptoms improved both significantly and rapidly, and that these effects lasted from three days to … Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on … Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT- resistant major

7. #05 DEPRESSION (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1512.pdf
   December 01, 2015 - and the severity of certain depressive symptoms. … antidepressant, partly due to a hypothesized link between dysfunctional glutamate neurotransmission and depressive … symptoms observed in BPD and MDD.4 Preclinical studies indicate that ketamine’s antidepressant properties … Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT-resistant major … depression.

8. #05 DEPRESSION (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1312.pdf
   October 01, 2014 - Researchers believe that dysfunctional glutamate neurotransmission may play a major role in causing depressive … symptoms in both BPD and MDD, although its exact mechanism of action is still unknown.59,61 Studies … symptoms improved both significantly and rapidly and that these effects lasted from 3 days to several … Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on … Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT- resistant major

9. #05 DEPRESSION (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/depression_hi_impact.pdf
   October 01, 2014 - believe that dysfunction in glutamate neurotransmission could play a major role in the etiology of depressive … symptoms, although its exact mechanism of action is still unknown. 24 Research suggests that N-methyl-D-aspartate … , investigators concluded, “Within 40 minutes, depressive symptoms significantly improved in subjects … Deep brain stimulation for treatment-resistant depression. … depression.

10. Traumatic Brain Injury and Depression (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury-surveillance-160902.pdf
    January 30, 2014 - " Depression"Scale"scores"(HADS)"(treatment"M=10.63"[2.67]h"waitlist"M=9.56"[3.09])"suggest" that"participants"experienced"mildKtoKmoderate"depressive"symptoms … $symptoms$(CES"D$M=16$[mild$ depression]S$n=67)$found$a$significant$ reduction$in$depressive$symptoms … $and$anxiety$and$reducing$depressive$symptoms. … $symptoms$ (CES"D$M=16$[mild$ depression]S$n=67)$found$a$ significant$reduction$in$ depressive$symptoms … $Brain$morphometry$changes$and$ depressive$symptoms$after$traumatic$brain$injury.$Psychiatry!

11. depression-pregnancy-postpartum-protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
    March 29, 2013 - Refinements of note include: • Population: We clarified that the scope includes treatment of subthreshold depressive … symptoms and added treatment during the time of conception. … • Subthreshold depressive symptoms which have become the subject of clinical attention. … Speed and duration of response/remission o Relapse o Recurrence o Change in core depressive symptoms … Prevalence of mood symptoms and depressions during pregnancy: implications for clinical practice and

12. Treatment of Depression in Children and Adolescents | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/childhood-depression/research
    April 10, 2020 - Cognitive behavioral therapy (CBT), fluoxetine, escitalopram, and combined fluoxetine plus CBT may reduce depressive … symptoms in the short term; clinical significance is unclear. … cognitive behavioral therapy (CBT), fluoxetine, escitalopram, and combined fluoxetine and CBT may improve depressive … symptoms (1 randomized controlled trial [RCT] each, n ranges from 212 to 311); whether the magnitude … Treatment of Depression in Children and Adolescents: A Systematic Review.

13. Depression | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/depression/

14. Efficacy and Safety of Screening for Postpartum Depression | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/depression-postpartum-screening/research
    April 09, 2013 - Review Feb. 1, 2017 Disposition of Comments Report Efficacy and Safety of Screening for Postpartum Depression … Scale, 4 on the Postpartum Depression Screening Scale, 4 on different versions of the Beck Depression … Fifteen studies analyzed the association between risk factors and postpartum depression. … on five studies, there was low to moderate strength of evidence that screening resulted in decreased depressive … symptoms and improved mental health; in four of these studies, improvement in depressive symptoms was

15. Depression-Treatment-Ssri Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_executive.pdf
    April 01, 2012 - symptoms (a score within the normal range of the symptom scale). … symptoms are risk factors for relapse and negative predictors of long-term outcome.22 Clinicians are … Depression and diabetes: Impact of depressive symptoms on adherence, function, and costs. … Relationship between changes in depressive symptoms and unhealthy lifestyles in late middle aged and … Depressive Symptoms and clinical status during the treatment of adolescent suicide attempters (TASA

16. Depression-Postpartum-Screening Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_executive.pdf
    May 01, 2013 - However, the prevalence of depressive symptoms not meeting diagnostic criteria for depression may be … symptoms. … symptoms 5 (8,071) Medium Consistent Direct Imprecise Low to moderate SOE for reduced number of … symptoms with screening, there are limited data on other maternal or infant health outcomes. … symptoms are substantially improved when screening, diagnosis, and treatment are provided by the same

17. Depression Treatment | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/depression-treatment
    April 10, 2020 - Treatment of Depression in Children and Adolescents Systematic Review April 10, 2020 … Adverse Effects of Pharmacological Treatments of Major Depression in Older Adults Systematic … March 28, 2019 Adverse Effects of First-line Pharmacologic Treatments of Major Depression

18. Postpartum Depression | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/postpartum-depression/

19. Treatment Resistant Depression Surveillance FINAL (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_surveillance.pdf
    April 01, 2016 - symptoms after two or more failed adequate trials? … symptoms after two or more failed adequate trials? … symptoms. … symptoms after two or more failed adequate trials? … symptoms after two or more failed adequate trials?

20. Treatment of Depression During Pregnancy and the Postpartum Period | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/depression-pregnancy-postpartum/research-protocol
    March 29, 2013 - Refinements of note include: Population: We clarified that the scope includes treatment of subthreshold depressive … symptoms and added treatment during the time of conception. … Subthreshold depressive symptoms which have become the subject of clinical attention. … duration of response/remission Relapse Recurrence Change in core depressive symptoms Anxiety … Prevalence of mood symptoms and depressions during pregnancy: implications for clinical practice and