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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-protocol.pdf
    April 17, 2024 - Definitions of effect sizes Effect size Definition Small effect MD 0.5 to 1.0 points on a 0 to 10-
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
    January 01, 2016 - intervention shows reduction in inappropriate or increase in appropriate prescribing based on minimal definitions … Those that did used inconsistent definitions and methods.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_disposition-comments.pdf
    August 12, 2016 - The definitions of the outcome measures could be improved. … The second paragraph of the RCT section of the MACE results describes study’s definitions. … We have expanded some definitions of outcomes that do not have a specific definition. … Most importantly, we have the range of definitions of major adverse cardiovascular events used by
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/allergy-seasonal_research-protocol.pdf
    March 08, 2012 - Definitions of symptom severity will be adapted from the Allergic Rhinitis in Asthma (ARIA) guidelines … The GRADE definitions are as follows: • High: high confidence that the evidence reflects the true … Definition of Terms Symptom severity ARIA guidelines provide the following definitions:6 • Mild
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/breastfeeding_research-protocol.pdf
    January 01, 2020 - Similar to the 2007 review, we will accept all definitions of “exclusive breastfeeding” as provided … qualify our conclusions (and perform subgroups analyses if feasible) with respect to those specific definitionsDefinitions of the Grades of Overall Strength of Evidence Grade Definition High We are very confident
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-273-anal-cancer-executive-summary.pdf
    August 01, 2024 - RCTs were limited by inconsistency in outcome definitions and measurement between trials, inadequately
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-disease-testing_research-protocol.pdf
    January 15, 2015 - The definitions of risk categories are based on those described in the ACCF/AHA 2012 Guideline.8 In … The review will attempt to stratify studies based on these characteristics if definitions are not provided … methodological or other characteristics (e.g., quality factors, diagnostic thresholds or criteria, outcome definitions … Comparative definitions for moderate-severe ischemia in stress nuclear, echocardiography, and magnetic
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/women-hiv_disposition-comments.pdf
    November 21, 2016 - example they note that menopausal women are included in several publications, but not whether valid definitions
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
    June 01, 2013 - 1 Comparative Effectiveness Review Number 112 Local Nonsurgical Therapies for Stage I and Symptomatic Obstructive Non–Small-Cell Lung Cancer Executive Summary Background Non–small-cell lung cancer (NSCLC) refers to any type of epithelial lung cancer other than small-cell lung cancer.1 The disease arises f…
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening-2010_research-protocol.pdf
    January 01, 2010 - Source: www.effectivehealthcare.ahrq.gov Published Online: October 24, 2011 Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of Screening for Methicillin-Resistant Staphylococcus aureus (MRSA) Amendment Date(s) if applicable: October 24, 2011 (Amendme…
  11. effectivehealthcare.ahrq.gov/sites/default/files/assessing-quality.ppt
    January 01, 2010 - Assessing the Quality of Individual Studies Assessing the Quality of Individual Studies Agency for Healthcare Research and Quality (AHRQ) Training Modules for Methods Guide on Effectiveness and Comparative Effectiveness Reviews Assessing the Quality of Individual Studies Systematic Review Process Overview * …
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-gain-prevention_disposition-comments.pdf
    March 25, 2013 - Response Peer Reviewer 1 Methods It would be helpful to know how the authors arrived at their definitions … Peer Reviewer 5 Methods Search strategies: Logical and clear Thanks Peer Reviewer 5 Methods Definitions … We defined clinically meaningful thresholds which could be considered definitions of comparative effectiveness
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_executive.pdf
    April 01, 2012 - These definitions reflect the consensus definitions developed by the International Urogynecological … While definitions of continence are similar, the definitions most commonly applied to improvement in … Based on women’s definitions of clinical success, we focused on clinical outcomes, including continence … The synthesis of evidence was hampered by differences in definitions of improvement in UI, quality … of benefits and harms with different treatments were possible only for studies that used similar definitions
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias-individual-studies_methods.pdf
    March 01, 2012 - assessment of risk of bias that justify research-specific risk-of- bias standards and operational definitions … x x Were cases and controls selected appropriately (e.g., appropriate diagnostic criteria or definitions … reporting harms, by study design Study design Quality considerations RCTs On study conduct: • Are definitions … Quality criterion 4: Adverse events prespecified and defined 1: study reports explicit definitions … Were the harms PREDEFINED using standardized or precise definitions? 2.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/suda-final-protocol.pdf
    October 02, 2018 - that address population characteristics; descriptions of the interventions and comparators; outcome definitions … Sensitivity analyses will examine robustness of results to alternative prior distributions; attribute definitions
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_protocol-140716.pdf
    April 03, 2014 - consequences.2 In the literature, the term insomnia can describe a symptom and/or a disorder and definitions … PICOTS Population(s) Adults, age 18 and above, with insomnia disorder (i.e. insomnia definitions
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/insomnia_research-protocol.pdf
    April 03, 2014 - consequences.2 In the literature, the term insomnia can describe a symptom and/or a disorder and definitions … PICOTS Population(s) Adults, age 18 and above, with insomnia disorder (i.e. insomnia definitions that
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_research-protocol.pdf
    June 11, 2014 - commonly defined as blood loss exceeding 500 mL following vaginal birth and 1000 mL following cesarean.1 Definitions … Public comments to the key questions emphasized the lack of universally accepted definitions for PPH … Postpartum hemorrhage--update on problems of definitions and diagnosis.
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-radiation_technical-brief.pdf
    November 01, 2009 - ...................................................................................5 Terminology, Definitions … Terminology, Definitions, and Conventions (Charged) Particle Beam Radiotherapy This includes external … However, the definitions of local control were heterogeneous within and across cancer types. … typically do not use a concurrent control, focus on heterogeneous populations, and employ different definitions
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-evidence-summary_0.pdf
    October 01, 2019 - There have been various definitions of what constitutes an ECOPD. … used outcomes as described in the original studies, which might have resulted in heterogeneity of definitions

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