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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-selection-harms-systematic-reviews.pdf
February 01, 2018 - harms
• Interpret composite endpoints by assessing the
individual harms that constitute them
• Record definitions … EPC reviews should also record the definitions used for composite harms, which often vary across studies
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_disposition-comments.pdf
January 01, 2011 - ferritin and TSAT concentrations across included studies, it
appears that studies used different definitions … heterogeneity
across studies exists regarding high degree of
heterogeneity across studies in the definitions
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effectivehealthcare.ahrq.gov/sites/default/files/assessing-the-risk-of-bias_draft-report.pdf
June 02, 2011 - systematic
misclassification of the exposure or intervention,
covariates, or outcomes because of variable definitions … templates for assessment of risk of bias that justify research-specific quality
standards and operational definitions … reporting harms, by study design
Study Design Quality Considerations
RCTs On study conduct:
Are definitions … Quality criterion 4: Adverse
events pre-specified and
defined
1: study reports explicit definitions … Were the harms PREDEFINED using standardized or precise definitions?
2.
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effectivehealthcare.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_june_2012.pdf
January 01, 2012 - Consistent with the definitions of health care interventions provided
by the Institute of Medicine
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth-disposition-121205.pdf
September 07, 2012 - Definitions and diagnostic criteria
are appropriate, complete and reflect the probable consensus of … All other maternal, fetal, or neonatal
outcomes were reported by fewer studies or
had incompatible definitions … The lack of
precision noted here relates to the varying
definitions of these rare events and their … researchers
will read this report carefully and avoid the problems cited in
excluded research and adopt the definitions … of the Science, under Methodological Priorities
the authors list, “Clear specifying of operational definitions
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/registry-of-patient-registries-development_research_0.pdf
February 01, 2012 - redundancy, and improve transparency; (2) to
encourage and facilitate the use of common data elements and definitions … redundancy, and improve transparency); (2) to
encourage and facilitate the use of common data elements and definitions … Registry owners may have proprietary claims on data elements,
definitions, and data that may significantly … To encourage and facilitate the use of common data elements and definitions in similar
conditions (to … complete for 95% of the data)
Form in which the data are collected (e.g., raw data)
Use of explicit definitions
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-rehospitalization_research.pdf
November 01, 2007 - Comparative Effectiveness of β-Adrenergic Antagonists on the Risk of Rehospitalization in Adults with Heart Failure
The DEcIDE (Developing Evidence to Inform Decisions about Effectiveness) network is part of
AHRQ’s Effective Health Care program. It is a collaborative network of research centers that
suppor…
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effectivehealthcare.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_2012-12-10.pdf
January 01, 2012 - Consistent with the definitions of health care interventions provided
by the Institute of Medicine
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-liver-metastases-therapies_research-protocol.pdf
September 27, 2012 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov
Published Online: September 27, 2012
Evidence-based Practice Center Systematic Review Protocol
Project Title: Local Therapies for Unresectable Colorectal Cancer Metastases to the Liver:
A Comparative Effect…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests_appendixes.pdf
May 23, 2005 - Effectiveness of Noninvasive Diagnostic Tests for Breast Abnormalities Appendices
Appendix A. Literature Search Strategies
Literature Search Strategies
Electronic Database Searches
The following databases have been searched for relevant information:
ClinicalTrials.gov (through April 2005)
Cochrane Data…