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1421. Arthritis and Nontraumatic Joint Disease (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/arthritis_hi_impact.pdf
      January 01, 2014 - Arthritis and Nontraumatic Joint Disease AHRQ Healthcare Horizon Scanning System – Potential High Impact Interventions Report Priority Area 01: Arthritis and Nontraumatic Joint Disease Potential High Impact Interventions Prepared for: Agency for Healthcare Research and Quality U.S. Department of Heal…

1422. Appendix C: Fiber Intake and Laxation in People With Normal Bowel Function Report (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/fiber-intake-prepub-final-research-appendix-c.xlsx
      January 01, 2024 - Appendix C: Fiber Intake and Laxation in People With Normal Bowel Function Report Design Details Author, Year, PMID, Country, Registry Number Study design Study Years Funding Conflict of interest (COI) Setting Inclusion criteria Exclusion criteria Durationofintervention Washout period N Outcome measurements/time p…

1423. Fiber-Intake-Final-Appendix-C (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/fiber-intake-final-appendix-c.xlsx
      January 01, 2024 - C-1 Design Details Table C-1. Design details Author, Year, PMID, Country, Registry Number Study Design Study Years Funding Conflict of Interest (COI) Setting Inclusion Criteria Exclusion Criteria Duration of Intervention Washout Period N Outcome Measurements/Time Period Outcome Measurement Timing Alexander (1) 20…

1424. Wheeled Mobility (Wheelchair) Service Delivery (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-service_technical-brief.pdf
      January 01, 2012 - Wheeled Mobility (Wheelchair) Service Delivery Wheeled Mobility (Wheelchair) Service Delivery Technical Brief Number 9 Technical Brief Number 9 Wheeled Mobility (Wheelchair) Service Delivery Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services…

1425. Disposition of Comments for CER 157 Appendicitis (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_disposition-comments.pdf
      December 14, 2015 - Disposition of Comments for CER 157 Appendicitis Comparative Effectiveness Review Disposition of Comments Report Research Review Title: Diagnosis of Right Lower Quadrant Pain and Suspected Acute Appendicitis Draft review available for public comment from November 4, 2014 to December 2, 2014. Re…

1426. Dementia-Agitation-Aggression Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-agitation-aggression_research-protocol.pdf
      November 13, 2014 - Confusion in the definition of agitation and aggression extends to the instruments used to evaluate … For behavioral health trials, the presence of treatment fidelity, that is, treatment definition and … Definition of Terms Not applicable. VII.

1427. Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-disposition.pdf
      June 22, 2017 - Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update” because: (1) the definition … Jiranek, MD, FACS) General Comments The systematic review’s definition of “sufficient” evidence … This systematic review has endorsed industry’s intentional exclusion of aspirin by their “a priori” definition … it is unclear from the methodology how an adverse bleeding event was identified and, in fact, the definition … for example, for total VTE (page 18, lines 53-54), the event rate could be 1.1 – 43.8% -- different definition

1428. Diagnosis and Treatment of Clinical Alzheimer's-type Dementia (CATD) (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
      November 02, 2018 - Definition of Terms AAFP American Academy of Family Physicians Aß beta amyloid ACP American College … composite outcome of SAEs We changed the wording to help the reader know this was a very specific definition … (1253) 1 X-1 Appendix 4 Risk of Bias Assessment Decision Aid Selection Bias DEFINITION … High Overall Attrition >30% High Unknown Overall Attrition High 5 X-5 Performance Bias DEFINITION … Detection Bias DEFINITION Systematic differences in outcomes assessment among groups being compared

1429. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/vte-prophyalaxis_research-protocol.pdf
      March 01, 2011 - taking anticoagulants or as VTE prophylaxis in patients without an increased bleeding risk. 4 Definition … Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical … Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical … Definition of Terms DVT = deep vein thrombosis, LMWH = low-molecular-weight heparin PE = pulmonary

1430. S66 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/s66.pdf
      October 01, 2007 - studies of NSAIDs use applied similar 90 days periods to define drug discontinuation,30 no standard definition … Patients could contribute more than 1 episode of use of the same regimen, as long as they met our definition … the study period 2,915,378 TennCare enrollees were potentially eligible and 26,837 (0.9%) met our definition … Toward a definition and method of assessment of treatment failure and treatment effectiveness: the case

1431. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
      October 01, 2010 - However, RR is not a reversible measure in terms that if the definition of an outcome event and nonevent … Therefore, while the definition of the outcome event needs to be consistent among the included studies … when using any measure, the investigators should be particularly attentive to the definition of an … factors: (1) factors that apply equally to all patients in a study, e.g., study design, quality and definition

1432. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
      October 01, 2010 - However, RR is not a reversible measure in terms that if the definition of an outcome event and nonevent … Therefore, while the definition of the outcome event needs to be consistent among the included studies … when using any measure, the investigators should be particularly attentive to the definition of an … factors: (1) factors that apply equally to all patients in a study, e.g., study design, quality and definition

1433. Prostate-Cancer-Test Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
      October 14, 2011 - followup  Measurements: equal, reliable, and valid (includes masking of outcome assessment)  Clear definition … following criteria for nonrandomized comparative intervention studies13,17:  Were the sample definition … Strength of evidence grades and definitions20 Grade Definition High High confidence that evidence … Definition of Terms Area under the curve (AUC) — area under the receiver operating characteristic

1434. Technical Brief 16 Disposition of Comments Report (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/advanced-care-decision-aids_disposition-comments.pdf
      July 29, 2014 - We chose to use a common, broad definition and kept the discussion of ACP itself brief to support the

1435. Multidisciplinary Rehabilitation Programs for Moderate to Severe Traumatic Brain Injury in Adults: Future Research Needs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation-future_research.pdf
      January 01, 2013 - By definition, multidisciplinary rehabilitation programs involve several provider types; therefore a … By definition, multidisciplinary rehabilitation programs involve several provider types; therefore, … Reporting guidance in published comparativeness studies with particular attention to intervention definition … Treatment definition in complex rehabilitation interventions.

1436. Disposition of Comments for CERs 155 156 Contast-Induced Nephropathy (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_disposition-comments.pdf
      January 07, 2016 - This is a very broad definition obviously and assumes that whoever was conducting the study(-ies) is … The definition of CIN (0.5 mg/dL or 25% change) is historical and although should be used for this review … It may be worth mentioning this context when the definition of "CIN" is described. … questionable, driven in large part by the nature of the clinical trials and issues related to the definition

1437. Disposition of Comments for CER 196 The Role of Immunotherapy in the Treatment of Asthma (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-196-disposition-comments-immunotherapy-asthma.pdf
      March 23, 2018 - Peer Reviewer #2 Introduction On page 12 line 10---Perhaps further definition/elaboration on … We added the definition of hypersensitivity Peer Reviewer #1 Results The … paragraph; "Recent alterations in grading of systemic versus local reactions, with a more liberal definition … We added the definition of the WAO grading of systemic reactions to the Methods section.

1438. S89 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
      October 01, 2007 - - atively clear criteria for diagnosis, whereas “dizziness” is a symptom with only a vague clinical definition

1439. Future Research Needs for Diagnosis of Obstructive Sleep Apnea (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
      February 01, 2012 - The stakeholders stated that there is a need for a new definition of the OSA syndrome that identifies … It should be noted that the definitive definition of OSA will remain unclear because whether the functional … Thus, the definition of the OSA syndrome requires information beyond the currently used measurements … A better definition of OSA syndrome will more specifically target therapy at those who are at risk and … It should be noted that the definitive definition of OSA will remain unclear because whether the functional

1440. Disposition of Comments Report for Recurrent Nephrolithiasis in Adults (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_disposition-comments.pdf
      July 26, 2012 - was directed at patients who had excess urine Ca as a stone risk, even if not formally meeting the definition … Although the issue is complicated, for future carefully designed trials, we tend to favor a strict definition