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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
    October 18, 2010 - support status, working status), singleton vs. multiple gestations, gestational age at preterm labor, definition … control for important confounders5 x Criteria for assessment of neonatal or maternal harms: definitionDefinition of Terms Not applicable VII.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment_research-protocol.pdf
    September 13, 2012 - We will use the standard definition of a chronic venous leg ulcer, which is the presence of an active … Definition of Terms FDA = U.S. … We will use the standard definition of chronic venous leg ulcer: o Presence of an active ulcer for
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer-update_disposition.pdf
    December 09, 2014 - We are not aware of a consensus definition of “conventional” RT so will avoid mention. … sense, the problem arises when generalizing study findings to other populations. 2. - p.14, L.7: Definition … of SBRT: “…generally compromise…by definition…” this statement is self- contradictory 1. … The line “Regimens generally comprise a total dose by definition in five or fewer fractions” does … An interested reader would be better off with the average Wikipedia definition of the same terms.
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
    September 01, 2014 - Two issues related to the definition of diagnostic test categories merit additional description. … This operational definition was adopted by several of the primary studies we reviewed and the original … To assess the impact of this operational definition on our findings we performed a sensitivity analysis
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_disposition-comments.pdf
    December 14, 2015 - Disposition of Comments for CER 157 Appendicitis Comparative Effectiveness Review Disposition of Comments Report Research Review Title: Diagnosis of Right Lower Quadrant Pain and Suspected Acute Appendicitis Draft review available for public comment from November 4, 2014 to December 2, 2014. Re…
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-agitation-aggression_research-protocol.pdf
    November 13, 2014 - Confusion in the definition of agitation and aggression extends to the instruments used to evaluate … For behavioral health trials, the presence of treatment fidelity, that is, treatment definition and … Definition of Terms Not applicable. VII.
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-disposition.pdf
    June 22, 2017 - Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update” because: (1) the definition … Jiranek, MD, FACS) General Comments The systematic review’s definition of “sufficient” evidence … This systematic review has endorsed industry’s intentional exclusion of aspirin by their “a priori” definition … it is unclear from the methodology how an adverse bleeding event was identified and, in fact, the definition … for example, for total VTE (page 18, lines 53-54), the event rate could be 1.1 – 43.8% -- different definition
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
    November 02, 2018 - Definition of Terms AAFP American Academy of Family Physicians Aß beta amyloid ACP American College … composite outcome of SAEs We changed the wording to help the reader know this was a very specific definition … (1253) 1 X-1 Appendix 4 Risk of Bias Assessment Decision Aid Selection Bias DEFINITION … High Overall Attrition >30% High Unknown Overall Attrition High 5 X-5 Performance Bias DEFINITION … Detection Bias DEFINITION Systematic differences in outcomes assessment among groups being compared
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/vte-prophyalaxis_research-protocol.pdf
    March 01, 2011 - taking anticoagulants or as VTE prophylaxis in patients without an increased bleeding risk. 4 DefinitionDefinition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical … Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical … Definition of Terms DVT = deep vein thrombosis, LMWH = low-molecular-weight heparin PE = pulmonary
  10. S66 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s66.pdf
    October 01, 2007 - studies of NSAIDs use applied similar 90 days periods to define drug discontinuation,30 no standard definition … Patients could contribute more than 1 episode of use of the same regimen, as long as they met our definition … the study period 2,915,378 TennCare enrollees were potentially eligible and 26,837 (0.9%) met our definition … Toward a definition and method of assessment of treatment failure and treatment effectiveness: the case
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
    October 01, 2010 - However, RR is not a reversible measure in terms that if the definition of an outcome event and nonevent … Therefore, while the definition of the outcome event needs to be consistent among the included studies … when using any measure, the investigators should be particularly attentive to the definition of an … factors: (1) factors that apply equally to all patients in a study, e.g., study design, quality and definition
  12. effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
    October 01, 2010 - However, RR is not a reversible measure in terms that if the definition of an outcome event and nonevent … Therefore, while the definition of the outcome event needs to be consistent among the included studies … when using any measure, the investigators should be particularly attentive to the definition of an … factors: (1) factors that apply equally to all patients in a study, e.g., study design, quality and definition
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
    October 14, 2011 - followup  Measurements: equal, reliable, and valid (includes masking of outcome assessment)  Clear definition … following criteria for nonrandomized comparative intervention studies13,17:  Were the sample definition … Strength of evidence grades and definitions20 Grade Definition High High confidence that evidence … Definition of Terms Area under the curve (AUC) — area under the receiver operating characteristic
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/advanced-care-decision-aids_disposition-comments.pdf
    July 29, 2014 - We chose to use a common, broad definition and kept the discussion of ACP itself brief to support the
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation-future_research.pdf
    January 01, 2013 - By definition, multidisciplinary rehabilitation programs involve several provider types; therefore a … By definition, multidisciplinary rehabilitation programs involve several provider types; therefore, … Reporting guidance in published comparativeness studies with particular attention to intervention definition … Treatment definition in complex rehabilitation interventions.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_disposition-comments.pdf
    January 07, 2016 - This is a very broad definition obviously and assumes that whoever was conducting the study(-ies) is … The definition of CIN (0.5 mg/dL or 25% change) is historical and although should be used for this review … It may be worth mentioning this context when the definition of "CIN" is described. … questionable, driven in large part by the nature of the clinical trials and issues related to the definition
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-196-disposition-comments-immunotherapy-asthma.pdf
    March 23, 2018 - Peer Reviewer #2 Introduction On page 12 line 10---Perhaps further definition/elaboration on … We added the definition of hypersensitivity Peer Reviewer #1 Results The … paragraph; "Recent alterations in grading of systemic versus local reactions, with a more liberal definition … We added the definition of the WAO grading of systemic reactions to the Methods section.
  18. S89 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
    October 01, 2007 - - atively clear criteria for diagnosis, whereas “dizziness” is a symptom with only a vague clinical definition
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
    February 01, 2012 - The stakeholders stated that there is a need for a new definition of the OSA syndrome that identifies … It should be noted that the definitive definition of OSA will remain unclear because whether the functional … Thus, the definition of the OSA syndrome requires information beyond the currently used measurements … A better definition of OSA syndrome will more specifically target therapy at those who are at risk and … It should be noted that the definitive definition of OSA will remain unclear because whether the functional
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_disposition-comments.pdf
    July 26, 2012 - was directed at patients who had excess urine Ca as a stone risk, even if not formally meeting the definition … Although the issue is complicated, for future carefully designed trials, we tend to favor a strict definition

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