-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-quality-indicator-framework_research.pdf
April 01, 2010 - The defined population includes
seriously or terminally ill cancer patients, who are unlikely to recover … initiatives such as the
National Consensus Project (NCP)7 and NQF Palliative Care Framework8 have defined … All the indicators approved
by the NQF defined the denominator retrospectively from the time of death … Reliability depends on various factors,
including objectively defined concepts, precise specifications … Although the framework is defined as end-of-life, end-of-life
issues may be relevant from the time of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
April 01, 2007 - Registries are classified according to how the
populations are defined. … Disease or condition registries are
defined by patients having the same diagnosis, such
as cystic fibrosis … Requirements for quality assurance should be
defined during the registry’s inception and creation. … • Operational definitions of outcomes are clearly defined. … • The plan for generating and/or reviewing publications and presentations is defined.
-
effectivehealthcare.ahrq.gov/sites/default/files/fecal-incontinence_disposition-comments.pdf
March 21, 2016 - TEP 5
General
comments
The target population and audience are explicitly defined. … The other subgroups are not well defined, “mixed,”
“structural,” and “GI.” … Authors defined
etiologies differently. … While this may be relevant, these two terms are not
previously defined. … Each author
defined their own “standard care”.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sodium-potassium_research-protocol.pdf
April 18, 2017 - Among subpopulations defined by hypertension, diabetes, and obesity health
status.
2. … Among subpopulations defined by hypertension, diabetes, and obesity health
status.
3. … Among subpopulations defined by hypertension, diabetes, obesity and renal
health status. … Among subpopulations defined by hypertension, diabetes, and obesity health
status.
7. … Among subpopulations defined by hypertension, diabetes, and obesity health
status.
III.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
September 20, 2017 - Background and Objectives for the Systematic Review
Nature and Burden of Chronic Pain
Chronic pain, defined … osteoarthritis
o Key Question 4: Fibromyalgia
o Key Question 5: Primary chronic tension headache (defined … A small/slight effect was defined for pain as a mean between-group difference following treatment of … A moderate effect was defined for pain as a mean difference of 10 to 20 points on a 0- to 100-point … Large/substantial effects were defined as greater than moderate.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-draft-report-app-f.xlsx
August 18, 2025 - Were outcomes pre-specified and defined, and ascertained using accurate methods? … Were outcomes pre-specified and defined, and ascertained using accurate methods?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-269-respectful-maternity-care-summary.pdf
January 01, 2024 - Informants, and a Technical Expert Panel, investigators developed
pre-established eligibility criteria defined … There was no data on harms of RMC, but
frameworks identified in the literature clearly defined related … many literature review and synthesis
topics, the concept of respectful maternity care is still being defined
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-comments_0.pdf
October 11, 2019 - How was
serious adverse event defined?
We used number of events as listed in the methods. … Clinical failure was defined in the methods of the full
report. … The
term “early” is not defined – what does “during AECOPD”
mean. … The term “early” is not defined – what does “during
AECOPD” mean. … Outcomes are defined.
We thank the reviewer for the comments.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-appendix-c.xlsx
May 29, 2025 - Were Outcomes Prespecified and Defined, and Ascertained Using Accurate Methods?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-protocol-amendment.pdf
November 28, 2023 - daily intake
of indispensable AAs
● No comparator
Outcomes KQ1 Total protein requirement* as
defined … living for
older adults (65 years and
older)
Outcomes KQ2 Indispensable AA requirement*
as defined … as the lowest daily intake value for a nutrient that will meet the
need as defined by a specified indicator … for infants,
children,
adolescents (0-18
Inclusion criteria:
Total protein
requirement* as
defined … PICOTS)
Outcomes KQ2
Inclusion Criteria
Inclusion criteria:
Indispensable AA
requirement* as
defined
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatigue-sleepiness-protocol.pdf
July 01, 2023 - Clinicians are defined as any person providing healthcare to patients
(e.g., physician, nurse, physician … We will search for recent high quality systematic reviews defined using the criteria for
“Good” described … analysis systems
• Pharmacological agents (e.g., caffeine,
melatonin, sleep medications)
Comparator Defined … No defined historical or
contemporaneous cohort
comparison group
Outcome Patient outcomes:
• Mortality … We will search for recent high quality systematic reviews defined using the criteria for “Good” described
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-disposition-comments.pdf
November 22, 2024 - “inconclusive”, is not defined in the methods section of the report and
is inconsistent with the “implications … wording be made to match the methods where
precision is either “precise” or “imprecise” and imprecise defined
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2011_research.pdf
January 01, 2011 - We defined internal validity as the extent to which the
results of a study are correct for the subjects … and the associations detected are truly caused by
exposure.5 We defined biases the checklists should … Good credibility was defined
with a total score of 13 or more. … Justify acceptable response rate:______ and rate that can be defined as a major flaw of the
study___ … Justify acceptable response rate:______ and rate that can be defined as a major flaw of the
study__
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/incident-user-design_research.pdf
May 01, 2012 - reuptake inhibitors (SSRIs), they found that the one year rate was
slightly higher in incident users defined … antidepressant medication (6.03
per 1,000 person years; 95% CI, 5.54 to 6.55) than in incident users defined … Number 32
5
effectiveness in second-line therapy.25 For second-line therapy, the cohort would be defined … For example, should the date of incident use be
defined in relation to the medical procedure or the … (2) Evaluate first-line, second-line, and third-line therapy defined as incident users and
compare
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
September 21, 2012 - The individual
treatment effect can be defined as the contrast:
θ
i
= g(E[Y
i
(1)]) – g(E[Y
i … (i.e. correlated with
explanatory variables) so that u
subgroup1
(average
θ
i
for a subgroup defined … by level 1 of an
explanatory variable) ≠ u
subgroup2
(average u
i
for
a subgroup defined by level … 4 Creating such
a narrowly defined subgroup (the individual
patient) leads to an extremely challenging … Reporting of results from descriptive analysis of
subgroups defined by priority populations using an
-
effectivehealthcare.ahrq.gov/sites/default/files/estimation-and-reporting_chapter-3.pptx
January 01, 2013 - of Treatment Effect
Heterogeneity of Treatment Effect
Heterogeneity of treatment effect (HTE) is defined … Subgroup variables must be true covariates, that is, variables that are defined before an individual … conducting observational comparative effectiveness research and clearly state if and how subgroups will be defined … Using an informative forest plot to report results from descriptive analysis of subgroups defined by … limited effectiveness data will be included in the study and evaluated as subgroups
Subgroups should be defined
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia_executive.pdf
May 01, 2006 - Anemia severity is defined by hemoglobin
(Hb) concentration. … Mild anemia is defined as Hb from
10 g/dL to the lower limit of normal
ranges, while moderate anemia … Patients are usually transfused if Hb
falls to or below 8 g/dL, defined as severe
anemia. … Epo: 7% (0-30%) Darb: 5%
across studies) Epo: 7% (3%-11%) Control: 4% (0-23%) Control: 3%
1 Trials defined
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-appendix-e.xlsx
July 15, 2025 - Yes/No/Unclear Outcomes pre-specified and defined?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_clinician.pdf
October 01, 2015 - evidence regarding the efficacy, comparative
effectiveness, and harms of transitional care interventions (defined … A preventable readmission is
defined as one related to the previous admission if there
was a reasonable … interventions are
more or less efficacious in reducing readmissions or
mortality based on patient subgroups defined
-
effectivehealthcare.ahrq.gov/sites/default/files/protocol-social-isolation.pdf
January 01, 2013 - with poor psychological and physical outcomes, as well as
increased mortality.1,2 Social isolation is defined … as the lack of meaningful and sustained
connection to other people, while loneliness is defined as