-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/thromboembolism-update_research-protocol.pdf
February 17, 2016 - Treatment adherence/compliance
Interventions
• Pharmacologic VTE prophylaxis agents within the defined … vitamin K antagonists KQ 1, 4 (in combination), 5, 6
• Mechanical VTE prophylaxis devices within the defined … leading to readmission
§ Surgical site / joint bleeding
§ Bleeding leading to infection
§ As defined … Symptomatic
o Proximal
§ Treatment adherence
Adverse events
§ Major bleeding
o As defined
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-tests-proposals_research.pdf
January 01, 2009 - controlled clinical studies intended to provide a reasonable
assurance of safety and effectiveness in defined … sufficient in providing evidence of improvement or equivalence in patient outcomes if
there is a well-defined … there is not always a reference standard available, nor is it clear how the target
condition should be defined … subset of those tested, so sample size
requirements can be substantial.45 Trials of testing need a well-defined
-
effectivehealthcare.ahrq.gov/sites/default/files/whitepaper3-lijmer02262010-2.pdf
January 01, 2009 - controlled clinical studies intended to provide a reasonable
assurance of safety and effectiveness in defined … sufficient in providing evidence of improvement or equivalence in patient outcomes if
there is a well-defined … there is not always a reference standard available, nor is it clear how the target
condition should be defined … subset of those tested, so sample size
requirements can be substantial.45 Trials of testing need a well-defined
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-d.xlsx
January 01, 2023 - introduce some bias for outcome assessment
ITACA-S OS Low Low Low Low Low Low open label, but had pre-defined … concerns regarding blinding
ITACA-S Grade 3 to 5 AEs Low Low Low Low Low Low open label, but had pre-defined
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_disposition-comments.pdf
January 15, 2016 - TEP reviewer #5 General The target population is explicitly defined. … define an underlying latent
response distribution (like typically seen in a probit model),
with πjk defined … We also provide the probability of each treatment
being the best, where "best" is defined as having … We have defined this--"long" is in relation to a shorter pulse duration in the
comparison group. … reviewer #4 Results Figure 5, as implied in the discussion above, it is not clear
how clearance was defined
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-topic-refinement.pdf
November 01, 2022 - Where needed,
we used the following definitions for real-world data and real-world evidence as
defined … In the protocol, the
sponsors/investigators describe
plans for analyzing demographic
subpopulations, defined … studies may meet this
requirement only if the disease
or condition being studied is
life threatening as defined … studies may meet
this requirement only if the disease
or condition being studied is life
threatening as defined … In the protocol, the sponsors/investigators describe plans for analyzing
demographic subpopulations, defined
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
September 19, 2014 - Introduction
Background
Chronic pain, often defined as pain lasting
longer than 3 months or past the … We selected studies of adults (age >18 years) with chronic
pain (defined as pain lasting >3 months) … We defined long-term opioid therapy as use
of opioids on most days for >3 months; this threshold
was … instruments based on whether it evaluated
a consecutive or random sample of patients meeting pre-
defined … We were also unable to determine how
benefits and harms vary in subgroups, such as those
defined by
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-surveillance_research-protocol.pdf
May 19, 2011 - A well-defined clinical benefit of immediate therapy with curative intent has not been
demonstrated … geographical access
Question 2
How are active surveillance and other observational strategies defined
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause-protocol-130612.pdf
June 12, 2013 - Background and Objectives for the Systematic Review
Menopause is defined as the permanent cessation … the period from the last menses to death as postmenopause;1-3 the first 5 postmenopausal years
are defined … Question 4
Does effectiveness and adverse effects vary among subgroups of patients defined by … Data will be abstracted into tables created in DistillerSR, with elements defined by an
accompanying … follow-up in each arm
• Measurements equal, reliable, and valid
• Interventions comparable and clearly defined
-
effectivehealthcare.ahrq.gov/sites/default/files/technical-brief-34-health-worker-certification-summary.pdf
March 01, 2020 - American
Public Health Association
Community Health Worker
Section, a community health
worker is defined
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/recombinant-factor-viia_clinician.pdf
October 01, 2010 - rFVIIa in Premier database, 2000-2008*
* The unit of analysis was any hospital “case” of rFVIIa use—defined
-
effectivehealthcare.ahrq.gov/sites/default/files/communicating_risk_international_king.ppt
January 01, 2005 - inclusion:
Describes an information tool for use by consumers/patients
Addresses treatment of a defined
-
effectivehealthcare.ahrq.gov/sites/default/files/ijzerman_ahrq-webinar-mcda.pdf
January 01, 2011 - We have defined 3 criteria (Ci) and 3 levels (Li)
Cooking style Italian, Greek or Thai
Travel
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-antenatal-care.pdf
April 01, 2021 - visit, or instead of a “routine visit”)
Comparators Standard or routine antenatal care program
(as defined … Also consider service
provider)
Standard or routine antenatal care program
(as defined by the study … Furthermore, the various uses of telehealth
in antenatal care could be defined in a systematic review
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability.ppt
January 01, 2009 - Applicability is defined as the extent to which the results observed in published studies are likely … Defining Applicability
Defining Applicability
Applicability is defined as the extent to which the … improper definitions for outcomes, composite endpoints Outcomes (benefits and harms) and how they were defined … For outcomes, the researcher needs to evaluate the outcomes and how they were defined.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
April 20, 2015 - small but significant risk of
bleeding and tumor seeding – limiting its widespread use and a well-defined … Patients with surgical
chronic kidney disease (defined as chronic kidney disease as a result of surgical … strategies differ according to a patient’s demographic or clinical characteristics, or disease
severity defined … Risk of bias judgment
Bias in
measurement
of
interventions
3.1 Is intervention status well defined … Definition of Terms
Local recurrence - Local recurrence is defined as any persistent or recurrent
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/congestive-heart-failure-medicines_research.pdf
March 01, 2010 - ): Within African-American, Hispanic, or White racial/ethnic groups; and
• H0(3): Within subgroups defined … Statistical Analysis
We compared baseline characteristics across subgroups defined by H-ISDN exposure … No mortality hazard ratios were significantly <1.0 in the 15 subgroups defined by
racial/ethnic status
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
November 01, 2012 - Although we
abstracted data for severe fibrosis (defined as biopsy
showing METAVIR F3-F4, Ishak 4-6 … , or equivalent), we
summarized results for fibrosis (defined as biopsy
showing METAVIR F2-F4, Ishak … 3-6, or equivalent)
and cirrhosis (defined as biopsy showing METAVIR
F4, Ishak 5-6, or equivalent … Diagnostic accuracy: Platelet counts
vs. liver biopsy
Low For fibrosis (defined as METAVIR F2-F4, Ishak … For
cirrhosis (defined as METAVIR F4, Ishak 5-6, or equivalent), the
AUROC was 0.89 (range 0.64 to
-
effectivehealthcare.ahrq.gov/sites/default/files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
May 01, 2012 - EPC Investigator Other
Experts
Conclusion from SCEPC
Treatment failure at 5 years of
follow-up, defined … addition of neoadjuvant
hormonal therapy to RP did not
improve survival or cancer
recurrence rates, defined … There was a trend
toward more radiation proctitis,
defined aspersistent bleeding,
with 125I. … Treatment failure at 5 years of follow-up,
defined as acid phosphatase elevation on
two consecutive … There was a
trend
toward more radiation proctitis, defined as
persistent bleeding, with 125I.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
May 01, 2012 - EPC Investigator Other
Experts
Conclusion from SCEPC
Treatment failure at 5 years of
follow-up, defined … addition of neoadjuvant
hormonal therapy to RP did not
improve survival or cancer
recurrence rates, defined … There was a trend
toward more radiation proctitis,
defined aspersistent bleeding,
with 125I. … Treatment failure at 5 years of follow-up,
defined as acid phosphatase elevation on
two consecutive … There was a
trend
toward more radiation proctitis, defined as
persistent bleeding, with 125I.