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  1. effectivehealthcare.ahrq.gov/sites/default/files/study-objectives-and-questions-chapter-1.pptx
    January 01, 2013 - willing to accept a priori Describe the meaningful magnitude of change in the outcomes of interest as defined … to accept a priori; and describe the meaningful magnitude of change in the outcomes of interest as defined … Stakeholders are defined as individuals or organizations that use scientific evidence for decisionmaking … accept a priori; and for describing the meaningful magnitude of change in the outcomes of interest as defined … accept a priori; and for describing the meaningful magnitude of change in the outcomes of interest as defined
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
    May 14, 2010 - Osteoporosis is defined as a T-score of -2.5 or less. … Low bone mass or density is defined as a T-score between -2.5 and - 1. … Osteoporosis is defined as a T-score of -2.5 or less. … Osteopenia is defined as a T-score between -2.5 and -1. … is defined as treatment discontinuation without medical recommendation (Gass 2006).
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_disposition-comments.pdf
    July 26, 2012 - One defined it as >763 mg/day, two defined it as >600 mg/day, one defined it as >3.5 mmol/day, and … two defined it as >800 mg/day in men or >750 mg/day in women. … Of these, 2 defined it as <320 mg/day, 1 defined it as <273 mg/day, and 1 defined it as <3.4 mmol/day … The target population and audience are clearly defined. … The target population and audience are clearly defined.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pain-chronic_research-protocol.pdf
    July 28, 2010 - prevalence of chronic pain varies, depending on how the survey questions are asked and how chronic pain is defined … Researchers have estimated that from 10 to 20 percent of adults report having chronic pain when defined … is more appropriate than the biomedical model for disease states for which the cause is not clearly defined … The variation across studies in how MPP is defined has contributed to confusion in this area of research … The current evidence of the technology: In studies examining the effectiveness of MPPs (defined as
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_clinician.pdf
    August 01, 2016 - It has been traditionally defined, in the absence of an alternative etiology, as an increase in serum … Low-dose NAC was defined as 1200 mg/day or less. �� Statins plus NAC plus IV saline (or bicarbonate) … b Clinically important effect was defined by a risk ratio less than 0.75 or greater than 1.25. … b Clinically important effect was defined by a risk ratio less than 0.75 or greater than 1.25. ⬇ =
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_policymaker.pdf
    August 01, 2016 - A preventable readmission is defined as one occurring within 30 days of discharge and is clinically … The rate of preventable readmissions may be reduced by transitional care interventions, which are defined … evidence regarding the efficacy, comparative effectiveness, and harms of transitional care interventions (defined
  7. effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-2.xlsx
    January 01, 2017 - 0.67% (1/150) RR 0.34 (95% CI 0.01 to 8.17) *For the inpatient group. the duration of hospital stay was defined … CD not for fetal distress: 13.27% (54/407) vs. 11.35% (47/414) RR 1.17 (95% CI 0.81 to 1.69) -Study-defined … CD not for fetal distress: 14.42% (31/215) vs. 15.24% (32/210) RR 0.95 (95% CI 0.60 to 1.49) -Study-defined … : 0% (0/177) vs. 0% (0/96) RR 0.54 (95% CI 0.01 to 27.25) Nonreassuring intrapartum FHR trace (not defined … : 35.00% (14/40) vs. 30.56% (11/36) RR 1.15 (95% CI 0.60 to 2.19) CD due to: -Failed induction (not defined
  8. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/accountable-care-registries-guide-3rd-ed-addendum-white-paper-2018-5.pdf
    January 01, 2018 - A patient registry is defined as “…an organized system that uses observational study methods to collect … A cohort can also be defined by procedures, including orthopedic procedures for risk-based commercial … High utilizer cohorts may be defined as a subset within these larger cohorts, such as patients with … The data required to generate these risk estimates is highly dependent on how risk is defined. … Risk can be defined initially by using historical data from the defined patient population and categorizing
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-end-of-life-quality-meaures_research.pdf
    April 01, 2010 - Cancer type was defined by SEER histology codes. … For the prospective cohort, these were defined as the first surgeon, primary care physician, medical … For the retrospective cohort, these were defined as the last physician seen before death. … We defined surgeons as those with one of the following primary or secondary specialties: colon and … Reference period: Prospective: Not defined for this cohort.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_research-protocol.pdf
    October 01, 2013 - Background and Objectives for the Systematic Review Contrast induced nephropathy (CIN) is defined as … medium administration.1 However, sometimes CIN progresses to acute kidney injury (AKI), which can be defined … 1c.33, 34 We will consider including them in the review as long as they meet the inclusion criteria defined … ● High or moderate risk patients (as defined by clinical or demographic risk factors such as age … Definition of Terms All terms have been defined in the text of this protocol. VII.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_disposition-comments.pdf
    July 17, 2013 - The target population is also well-defined. … How the groups were defined? … Audience is well defined. I feel the key questions are clearly defined and appropriate. … SMD seemed to be arbitrarily defined. … No, this outcome was defined a priori.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonopioid-pharm-chronic-pain-protocol.pdf
    February 01, 2019 - Background and Objectives for the Systematic Review Understanding Chronic Pain Chronic pain is typically defined … Chronic headache is defined as 15 or more days each month for at least 12 weeks or history of headache … A small/slight effect was defined for pain as a mean between-group difference following treatment of … A moderate effect was defined for pain as a mean difference of 10 to 20 points on a 0 to 100-point VAS … Large/substantial effects were defined as greater than moderate (>20 points).
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
    December 01, 2017 - Compared with standard care, the evidence from two RCTs suggests that BT improved asthma control (defined … by the ACQ change from baseline to 12 months), health care utilization (defined by rescue medication … the intention-to-treat analysis in a single RCT suggests that BT had no effect on asthma control (defined
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_disposition-comments.pdf
    June 12, 2013 - Also, the term radical RT views and this page on the line 53 this should be defined. … We defined the term “BT” as brachytherapy in the sentence on line 33, ES-3. … Strategies are logical and well defined. 3. … Also, the term radical RT views and this page on the line 53 this should be defined. … We defined the acronym “BT” as brachytherapy in that section.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-treatment-ssri_research-protocol.pdf
    June 15, 2010 - 50 percent decrease in symptom severity from baseline is sufficient.4 Remission from depression is defined … TF is not consistently defined within the literature, but is generally understood to reflect patients … Treatment resistance is variably defined but usually refers to patients who have failed at least http … The treatment options following a failed response include the eight options (defined as interventions … A study with high risk of bias will be defined as fulfilling fewer than six criteria and not having
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
    March 19, 2018 - The term “intermittent” and “controller therapy” are defined within the glossary of the report. … We collected data from the included studies as it was defined. … TEP reviewer #3 I am glad you discussed the strength of evidence categories and how they were defined … It may be more specific to state that the intermittent dosing is defined as a change in dosing with … The only outcome in which study 48 contributed was a study defined exacerbation as fall in PEF to
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-information-exchange_research-protocol.pdf
    April 20, 2015 - receive care, increased attention has been paid to health information exchange (HIE), which has been defined … The Office of the National Coordinator for Health IT (ONC) has defined three key forms of HIE.11 • … If insufficient evidence is found of this type, we will explore observational study evidence (defined … For harms, in addition to RCTs, observational studies (defined as cohort studies comparing at least … High quality reviews will be defined as those assessed as being at low risk of bias, according to the
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer_research-protocol.pdf
    July 24, 2013 - The population of high-risk patients is defined, as per the AASLD clinical guidelines, as composed … , and patients with stage 4 primary biliary cirrhosis.6 Other definitions of high-risk patients as defined … as measured with scales such as the Short-Form Health Survey (SF- 36) or EuroQol 5D (EQ-5™) or as defined … The population of high risk patients is defined, as per the American Association for the Study of Liver … Other definitions of high risk patients as defined by the primary studies will be accepted.
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
    December 11, 2018 - and Objectives for the Systematic Review Nature and Burden of Chronic Pain Chronic pain, often defined … Population(s): Adults (including pregnant or breastfeeding women) with the following chronic pain (defined … A small/slight effect was defined for pain as a mean between-group difference following treatment of … A moderate effect was defined for pain as a mean difference of 10 to 20 points on a 0- to 100-point … Large/substantial effects were defined as greater than moderate.
  20. OUTLINE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-end-of-life-measures-framework_research.pdf
    April 01, 2010 - The defined population includes seriously or terminally ill cancer patients, who are unlikely to recover … initiatives such as the National Consensus Project (NCP)7 and NQF Palliative Care Framework8 have defined … All the indicators approved by the NQF defined the denominator retrospectively from the time of death … Reliability depends on various factors, including objectively defined concepts, precise specifications … Although the framework is defined as end-of-life, end-of-life issues may be relevant from the time of

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