-
effectivehealthcare.ahrq.gov/sites/default/files/tympanostomy-tubes-disposition.pdf
May 05, 2017 - Also, I thought
the target population and
audience were explicitly
defined. … In this case "late" has been
specifically defined as 12-24 months an has been
retained in preference … Peer
Reviewer #1
Methods P 47
Line 30: How was
sufficiently similar defined? … How is premature defined? … We have further noted that definitions are often
different, poorly defined.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-disposition.pdf
May 05, 2017 - Also, I thought
the target population and
audience were explicitly
defined. … In this case "late" has been
specifically defined as 12-24 months an has been
retained in preference … Peer
Reviewer #1
Methods P 47
Line 30: How was
sufficiently similar defined? … How is premature defined? … We have further noted that definitions are often
different, poorly defined.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/disparities-quality-improvement_research-protocol.pdf
February 23, 2012 - differences in
health care needs or preferences of the patient, but to other factors.1 Such disparities,
defined … These populations will be defined by race/ethnicity, socioeconomic status, insurance
status, sex, sexual … vaccination
End-stage renal disease
Studies must include: (a) members of a target population as defined … by positive health outcomes for individuals and populations.14
Improvement of quality: Broadly defined … disparities: Differences in health outcomes and their determinants between
segments of the population, as defined
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
December 15, 2010 - Briefly, five general comments were as follows: 1) The review scope should be defined to the most
common … taking at least one specific cardiovascular drug or one specific
class of cardiovascular drugs as defined … of a meal or diet
We will include studies only where the supplement(s) of interest is clearly defined … For major review outcomes (defined below in Grading the Evidence), we will rate the overall risk of … bias as low, moderate, or high as defined in Section VI.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-204-obesity-disposition-comments.pdf
December 01, 2017 - Thank you for your comment—the report
title is pre-defined by AHRQ and NIH. … I do not recall that the
authors explicitly defined the target population or audience. … There continues to be debate about
the definition of a natural experiment so we
broadly defined it. … We clarified that we defined macronutrients
according to this reference: Dietary
Reference Intakes … Outcomes are defined clearly.
Thank you.
Reviewer #7: Methods This is a very large literature.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
February 01, 2008 - Treatment failure
at 5 years of followup, defined as acid phosphatase
elevation on two consecutive followup … There was a trend
toward more radiation proctitis, defined as
persistent bleeding, with 125I. … Urinary
dysfunction, defined as no control or frequent leaking
of urine, occurred in 14 percent of men … (AE defined as the
first occurrence of an event and higher incidences of hot flashes.)
11
Table … Conventional-dose Medium 2 trials: Trial 1, Trial 2 (low-risk subgroup only, defined as T1/2,
(70 Gy
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_clinician.pdf
February 01, 2016 - Tolerance, as defined by either of the following:
a. … The
severity of the AUD is defined as follows: mild = the presence of two
to three symptoms; moderate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
April 01, 2010 - global assessment, and
joint imaging.24 However, published studies have interpreted improvement and defined … treatment
success inconsistently.18,19,25,26 Instead of measuring consistently defined clinical outcomes … o Chronic OA is defined as meeting diagnostic criteria and having symptoms of OA for
>2 months.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/childhood-cancer-disposition-comments.pdf
February 16, 2022 - Under “Purpose and Scope,” we
defined the degrees and specialties
included in our review.
4 Peer … The target population
and audience are explicitly defined and the key questions are
appropriate and … Thus, this
report contributes a re-
conceptualization based on the
4 dimensions we identified and defined … Although I do not see
“mid-range theory” defined. Methods seems appropriate
and transparent. … The target population is clearly defined.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-outcome-measure-harmonization-depression.pdf
November 01, 2020 - an initial Patient Health Questionnaire (PHQ-9)* score > 9 who demonstrates
a response to treatment defined … diagnosis of major depression or dysthymia and
an initial PHQ-9* score > 9 who demonstrates remission defined … a diagnosis of major depression or dysthymia and
an initial PHQ-9* > 9 who demonstrates remission (defined … of at least 2 months’ duration and subsequently experiences a recurrence
of a depressive episode, defined … as a 50 percent increase in PHQ-9 score
or defined as a PHQ-9 score > 9 OR hospitalization for depression
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
March 29, 2023 - Background and Objectives for the Systematic Review
Chronic pain, defined as pain lasting longer than … A small/slight effect is
defined for pain as a mean between-group difference following treatment of … A moderate effect is defined for pain as a mean difference of 10 to 20
points on a 0- to 100-point VAS … Large/substantial
effects are defined as greater than moderate. … , 2023
Table 1:
Population
Excluded subacute pain Added subacute
pain
Subacute pain, often
defined
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_1-user-guide-to-ocer_130129.pdf
August 13, 2012 - While stakeholders
may be defined in multiple ways, for the purposes
of this User’s Guide, a broad … Hence, stakeholders are defined as individuals
or organizations that use scientific evidence for
decisionmaking … to accept a priori. o
Describe the meaningful magnitude of change in
the outcomes of interest as defined
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/public-reporting-cost-measures_disposition-comments.pdf
March 05, 2015 - This isn’t defined until page 15 – too late. … We have defined
in the background section
63. … Reviewer #6 Background I think the scope of the review, as it is defined (on page 5, line 14 and elsewhere
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management_research-protocol.pdf
January 01, 2014 - VHA, the Indian Health Service, non–U.S. single-payer system)
● Comparators
o Usual care, as defined … Drug therapy problems that resolved as defined by primary studies but typically
includes the following … delivery of MTM
services occurs almost exclusively in the
inpatient setting
Interventions • As defined … One-time corrective interventions related
to medication management
Control
interventions
As defined … in the PICOTS criteria
Outcomes As defined in the PICOTS criteria • Studies that do not include
-
effectivehealthcare.ahrq.gov/sites/default/files/methodsguidenorris_060420101.pdf
June 01, 2010 - Observational studies of interventions are defined herein as those where the investigators
did not assign … Systematic reviewers should look carefully for how investigators defined new users. … Selective outcome reporting is defined as the selection of a subset of the original
variables recorded … research than registries in which enrollment has been defined by disease onset
because disease-based … In the CER work plan or protocol,
8
reviewers start with a clearly defined review question with
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
June 01, 2010 - Observational studies of interventions are defined herein as those where the investigators
did not assign … Systematic reviewers should look carefully for how investigators defined new users. … Selective outcome reporting is defined as the selection of a subset of the original
variables recorded … research than registries in which enrollment has been defined by disease onset
because disease-based … In the CER work plan or protocol,
8
reviewers start with a clearly defined review question with
-
effectivehealthcare.ahrq.gov/sites/default/files/ebc-challenge-1stplace-qrmedica.pdf
January 01, 2013 - Recurrent Otitis Media (ROM) is defined as three or
more episode in six months, or four or more
episodes … Otitis Media with Effusion (OME) is defined as fluid
in the middle ear without signs of symptoms of
acute
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_research-protocol.pdf
March 13, 2012 - GEP tests use
defined protocols to evaluate the specimens to be analyzed: preparing the RNA samples, … for the
outcomes of cancer recurrence or death)
For this report, data for clinical validity is defined … Clinical validity is also defined as the relationship (e.g., sensitivity,
specificity, accuracy, etc … Clinical utility is defined as the balance of benefits and harms when GEP
testing is used to impact … and Simon,13 a GEP is a biomarker in which the expression levels of multiple genes are
combined in a defined
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
January 01, 2010 - Effectiveness Reviews
Comparative Effectiveness Reviews
A 2007 Congressional Budget Office report defined … Heterogeneity across the defined PICOTS may result in inconsistency in both the effect size and the direction … fact that identification of gaps is an iterative process in which criteria for the study design are defined … commonly used to screen OSs for inclusion in CERs:
Minimum duration of followup
Minimum sample size
Defined … These criteria may include minimum duration of followup, minimum sample size, a defined threshold for
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-seniors-death_research.pdf
August 01, 2007 - APM initiators were defined as having used no
APM in the year prior to the index use. … independent predictors of death and were related to APM use in earlier research, including
arrhythmias defined … and other cardiac arrhythmia diagnoses plus
use of a Group I-IV antiarrhythmia medication, diabetes defined … heart failure (CHF), acute myocardial infarction (MI) other
evidence of ischemic heart disease (angina defined … Adjusted models were run
separately in strata defined by dementia and nursing home status.