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61. Recommendation: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication
    August 23, 2022 - CVD is the leading cause of mortality in the US, accounting for more than 1 in 4 deaths. … In 2019, there were an estimated 558,000 deaths caused by coronary heart disease and 109,000 deaths caused … to CVD in the US. 2 , 3 In 2019, an estimated 558,000 deaths were caused by coronary heart disease … and 109,000 deaths were caused by ischemic stroke. … Deaths: leading causes for 2017. Natl Vital Stat Rep . 2019;68(6):1-77. 2.

62. Archived: Evidence Summary: Aspirin Use to Prevent Cancer: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cancer/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
    April 11, 2016 - cause of death. 2 In 2016, there will be an estimated 1,685,210 new cancer cases and 595,690 cancer deaths … among 103,787 participants, showed that cancer deaths were similar among participants assigned to aspirin … k = 3; n = 12,659 ‡ ; 1634 cancer deaths, CRC deaths not reported k = 6; n = 19,824; 54 CRC … deaths k = 34 § ; n = 69,224; 1226 cancer deaths k = 6; n = 35,535; 1632 incident cancer cases … k = 4; n = 14,033; 391 incident CRC cases, 240 CRC deaths k = 2; n = 7588; 216 incident CRC

63. Draft Recommendation: Cervical Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/cervical-cancer-screening-adults-adolescents
    December 10, 2024 - In 2024, there will be an estimated 13,820 new cases of cervical cancer and 4,360 deaths. 2 The mortality … hysterectomy rates: White women had a hysterectomy-corrected cervical cancer mortality rate of 4.7 deaths … per 100,000 persons whereas Black women had a mortality rate of 10.1 deaths per 100,000 persons, resulting … . 4-6 Native American/Alaska Native women also have higher rates of cervical cancer mortality (3.0 deaths … have a significantly higher incidence rate of cervical cancer and slightly higher mortality rate (2.5 deaths

64. Procedure Manual Appendix VIII. Standardization of Outcome Tables | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-appendix-viii-standardization-outcome-tables
    July 01, 2017 - Outcome measures (harms and benefits): Deaths (where relevant).

65. Recommendation: Bladder Cancer in Adults: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/bladder-cancer-in-adults-screening
    August 15, 2011 - It is the seventh-leading cause of solid cancer-related deaths. … In comparison, in 2009 there were an estimated 219,440 new cases of lung cancer and 159,390 deaths, 146,970 … new cases of colorectal cancer and 49,920 deaths, 192,280 new cases of prostate cancer and 27,360 deaths … , and 11,270 new cases of cervical cancer and 4070 deaths 1 .

66. Final Recommendation Statement: Cervical Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/cervical-cancer-screening
    August 21, 2018 - Importance The number of deaths … widespread cervical cancer screening and continue to decline, from 2.8 per 100,000 women in 2000 to 2.3 deaths … The overall mortality rate from cervical cancer among African American women is 10.1 deaths per 100,000 … 10-12 American Indian/Alaska Native women also have higher rates of cervical cancer mortality (3.2 deaths … from 8.34 to 0.76 deaths per 1000 women a Primary hrHPV testing Every 5 y 4 RCTs of hrHPV

67. Screening for Colorectal Cancer: U.S. Preventive Services Task Force Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/6hyj7-3s6Qxs-brqhxPVxD
    June 06, 2017 - of persons who are screened because that will have the largest effect on reducing colorectal cancer deaths … ations for eachmethod.Figure 3 presents theestimatednumberof life-years gained, colorectal cancer deaths … Direct Visualization Tests Several RCTs have shown that flexible sigmoidoscopy alone reduces deaths … averted per 1000 individuals screened which include the SimulationModel Model Estimates, CRC Deaths … years (incidence rate ratio, 0.73 [95% CI, 0.66-0.82]), or about 9 to 14 fewer colorectal cancer deaths

68. Archived: Latent Tuberculosis Infection: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/latent-tuberculosis-infection-screening-september-2016
    September 06, 2016 - The trial reported fewer deaths attributable to tuberculosis among participants receiving treatment with … isoniazid (0 vs 3 deaths in the placebo group; RR, 0.14 [95% CI, 0.01 to 2.78]), although this difference … The other 2 treatment trials compared either rifampin with isoniazid and found zero deaths in either … than with placebo, although this finding was not statistically significant (0.14 vs 0 deaths per 1000 … , 1.72 to 6.28]). 2  None of these trials, which were more recent than the IUAT trial, reported any deaths

69. Screening for Oral Cancer: A Brief Evidence Update (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/bNvmg937mA6ks3n448uEUD
    November 01, 2004 - Forty-seven cancers (7 resultant deaths) were diagnosed in the intervention group and 16 cancers (9 resultant … deaths) were diagnosed in the control group.

70. Archived: Brief Evidence Update: Oral Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-update-2004/oral-cancer-screening-2004
    February 04, 2004 - Forty-seven cancers (7 resultant deaths) were diagnosed in the intervention group and 16 cancers (9 resultant … deaths) were diagnosed in the control group.

71. Screening for Depression and Suicide Risk in Adults: US Preventive Services Task Force Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/bF_Y9vcT3eNPdHjTxPZsUZ
    April 17, 2023 - [2019 data]).12 From 2001 to 2017, there was a 31% in- crease in suicide deaths.13 Over the last decade … numbered 45 855, which was 3% less than in 2019 (47 511 deaths).15,16 However, rates did not de- cline … among Black and Hispanic/Latino persons.17 Rates of suicide attempts and deaths vary by sex, age, and … Studies reported few health outcome events (suicide deaths), making determination of benefits uncertain … Important risk factors for suicide deaths include previ- ous suicide attempts (strongest predictor of

72. JAMA JATS (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/Nvjr8BPsZhy4XGc7-rGjAH
    June 18, 2018 - Services Task Force Recommendation Statement US Preventive Services Task Force IMPORTANCE The number of deaths … substantially since the implementation of widespread cervical cancer screening and has declined from 2.8 to 2.3 deaths … The overall mortality rate from cervical cancer among African American women is 10.1 deaths per 100 000 … from 8.34 to 0.76 deaths per 1000 womena Primary hrHPV testing Every 5 y 4 RCTs of hrHPV testing vs … from 8.34 to 0.30 deaths per 1000 womena Abbreviations: CIN, cervical intraepithelial neoplasia; HPV

73. Archived: Tobacco Use Prevention: Counseling, 1996 | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/tobacco-use-prevention-counseling-1996
    January 01, 1996 - First, tobacco is one of the most potent of human carcinogens, causing an estimated 148,000 deaths among … artery, cerebrovascular, and peripheral vascular disease. 2 , 3 It is responsible for about 100,000 deaths … from coronary heart disease and 23,000 deaths due to cerebrovascular disease each year. 1 Third, smoking … is an important risk factor for respiratory illnesses, causing 85,000 deaths per year from pulmonary … Smoking during pregnancy causes about 5-6% of perinatal deaths, 17-26% of low-birth-weight births, and

74. Archived: Evidence Summary: Harms of Screening for Breast Cancer: Breast Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-harms-of-screening-for-breast-cancer/breast-cancer-screening-january-2016
    January 11, 2016 - Models estimated 2 to 11 screening-related deaths from radiation-induced cancer per 100,000 women using … cancer cases and deaths in 100,000 women: Annual 40-49 y: 59 cases; 7.6 deaths Annual 50-59 … y: 27 cases; 3.1 deaths Biennial 50-59 y: 14 cases; 1.6 deaths Annual 40-59 y: 85 cases; 11 … deaths Annual 40-49 y, biennial to 59 y: 73 cases; 9 deaths Annual 40-55 y, biennial to 74 … y: 86 cases; 11 deaths LAR = lifetime attributable risk.

75. Archived: Abdominal Aortic Aneurysm: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/abdominal-aortic-aneurysm-screening-2014
    June 23, 2014 - at the same diameter (hazard ratio [HR], 3.76 [95% CI, 2.58 to 5.47]). 14 However, AAA-associated deaths … Almost all deaths from ruptured AAA occur after age 65 years, and most deaths in women occur after age … More than two-thirds of deaths from AAA occur in women age 80 years or older, as the Chichester trial … group (17 vs. 6 deaths); however, 43% of the fatal ruptures were from AAAs measuring larger than 5.5 … Mortality related to AAAs accounted for approximately 7% of all deaths recorded. 1 , 2 In addition

76. Behavioral Counseling Interventions: An Evidence-based Approach - Table 1 | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/behavioral-counseling-interventions-an-evidence-based-approach---table-1
    November 01, 2013 -     Females     Males 72 74 50 50 Alcohol-related auto deaths

77. Screening for Latent Tuberculosis Infection in Adults: U.S. Preventive Services Task Force Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/Wx_w92ukxeDvNShoRQXbhP
    September 06, 2016 - 9.6 million persons were estimated to have con- tracted tuberculosis, and an estimated 1.5 million deaths … The trial reported fewer deaths attributable to tuberculosis among participants receiving treat- ment … The other 2 treatment trials compared either rifampin with isoniazid and found zero deaths in either … than with placebo, although this finding was not sta- tistically significant (0.14 vs 0 deaths per 1000 … 95% CI, 1.72-6.28]).2 None of these trials, which were more recent than the IUAT trial, reported any deaths

78. Archived: Breast Cancer: Medications for Risk Reduction | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction-2002
    July 08, 2002 - Although the USPSTF concluded that early detection of breast cancer through mammography has reduced deaths … Another approach to reducing breast cancer deaths is chemoprevention for primary prevention of cancer … No deaths attributed to endometrial cancer occurred in the trial. 7 Raloxifene has not been associated … hormonal, cytotoxic, or immune therapy. 133 randomised trials involving 31,000 recurrences and 24,000 deaths

79. Recommendation: Cervical Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/cervical-cancer-screening
    August 21, 2018 - The overall mortality rate from cervical cancer among African American women is 10.1 deaths per 100,000 … 10-12 American Indian/Alaska Native women also have higher rates of cervical cancer mortality (3.2 deaths … from 8.34 to 0.76 deaths per 1000 women a Primary hrHPV testing Every 5 y 4 RCTs of hrHPV … from 8.34 to 0.29 deaths per 1000 women a Cotesting Every 5 y 4 RCTs of cotesting vs cytology … from 8.34 to 0.30 deaths per 1000 women a a Outcomes calculated from models of cohorts of women

80. Final Recommendation Statement: Breast Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/breast-cancer-screening
    April 30, 2024 - screening has a more favorable balance of benefits to harms (eg, life-years gained or breast cancer deaths … biennial screening starting at age 40 years until 74 years would lead to 1.3 additional breast cancer deaths … Thus, biennial screening starting at age 40 years would result in 1.8 additional breast cancer deaths … averted (median, 9.2 deaths averted for screening from ages 50 to 74 vs 10.7 deaths averted, across … 4 models) per 1000 women screened for Black women ( Table 2 ; note that the 1.8 deaths averted is the