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www.uspreventiveservicestaskforce.org/uspstf/document/how-did-the-uspstf-arrive-at-this-recommendation-/prostate-cancer-screening-2012
May 11, 2012 - The number of prostate cancer deaths in recent years has declined. Why is this? … The main goal of a cancer screening test is to reduce the number of deaths from the disease. … The Task Force found that the reduction in prostate cancer deaths from PSA screening is at most very … The number of prostate cancer deaths in recent years has declined. Why is this? … prostate cancer is such a slow-growing disease, large clinical trials have shown us that any reduction in deaths
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/LNtA2SDWjpsDwjXvsH4F5m
April 17, 2023 - in the US
during 2014 to 2017.5 Most deaths attributed to hypertensive disor-
ders of pregnancy (65% … vs 12.7 maternal deaths per 100 000
live births in 2007 to 2016, respectively), with hypertensive dis … -
orders of pregnancy accounting for 12.8% of pregnancy-related
deaths.14 Native American/Alaska Native … Pregnancy-related deaths: data from
14 US Maternal Mortality Review Committees,
2008-2017. … Racial/ethnic disparities in pregnancy-related
deaths—United States, 2007-2016.
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www.uspreventiveservicestaskforce.org/uspstf/document/modeling-report-radiation-induced-breast-cancer-and-breast-c/breast-cancer-screening-january-2016
April 20, 2015 - commissioned a decision analysis to estimate the number of radiation-induced breast cancer cases and deaths
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/TAgAUJ5QoaRfV3M8fApBoN
June 03, 2019 - in-
cluded in
analysis
(follow-
up vs.
evalua-
tion
method)
Breast cancer
deaths diag-
nosed within … Method for
verifying
breast
cancer
deaths
Blinded review
of the death
certificate
and medical
records … ; un-
clear how
deaths were
selected for
review
Blinded review of all deaths of
women known to have … Even in the best
screening settings, most deaths from breast cancer are not
currently prevented. … We considered
blinded review of deaths a requirement for a quality rating
of fair or better.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/HZGtYqL_8u57Gkc6YFctmT
August 21, 2018 - Lifetime number of tests, colposcopies, disease detection,
false-positive results, cancer cases and deaths … cancer screening strategies
were estimated to result in substantial reductions in cancer cases and deaths … For example, cervical cancer deaths associated with the guidelines-based strategies
ranged from 0.30 … to 0.76 deaths per 1000 women, whereas new strategies involving
primary hrHPV testing or cotesting were … associated with fewer cervical cancer deaths,
ranging from 0.23 to 0.29 deaths per 1000 women.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/prostate-cancer-screening-2012
May 15, 2012 - Seventy percent of deaths due to prostate cancer occur after age 75 years. 1
Detection
Contemporary … The European trial found a reduction in prostate cancer deaths of approximately 1 death per 1000 men … Even in the "core" age group of 55 to 69 years in the ERSPC trial, only 462 of 17,256 deaths were due … After 15 years of follow-up, the prostate cancer mortality rate was 18 deaths per 1000 person-years. … For men with well-differentiated prostate cancer, it was 6 deaths per 1000 person-years; far more of
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer-screening-2002
September 03, 2002 - In the Swedish Two-County Trial and the Gothenburg and Stockholm trials, review of deaths was unblinded … Even in the best screening settings, most deaths from breast cancer are not currently prevented. … The relatively low numbers of events means that misclassification or biased exclusion of a few deaths … We considered blinded review of deaths a requirement for a quality rating of fair or better. … ; unclear how deaths were selected for review
Blinded review of all deaths of women known to have
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/lung-cancer-screening
March 09, 2021 - Screening does not prevent most lung cancer deaths; thus, smoking cessation remains essential. … associated with lung cancer mortality reduced by 13.0% vs 9.8%, with avoiding 503 vs 381 lung cancer deaths … models to determine eligibility for lung cancer screening could be associated with reduced lung cancer deaths … prediction models shifted screening to persons of older age and increased the number of lung cancer deaths … in a defined population of high-risk persons can prevent a substantial number of lung cancer–related deaths
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/WN7F3WW6RQFDkHay87a3Dx
November 18, 2020 - in a defined population of
high-risk persons can prevent a substantial number of lung
cancer–related deaths … Screening does not prevent most lung cancer deaths; thus,
smoking cessation remains essential. … this level of mortality benefit and also maxi-
mize, or come close to maximizing, both lung cancer deaths … prediction
models shifted screening to persons of older age and increased
the number of lung cancer deaths … to 90 years, or 1 death caused for every 13.0 vs 18.5 lung cancer
deaths avoided by screening.14
When
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/n6eeEADXc8hR25c3XkgezA
Recommendations
BACKGROUND
Summary
Mammography is an important tool in reducing the number of deaths … between the ages of 40 to 49 years may reduce the risk of
dying of breast cancer, but the number of deaths
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/-68R8Lt-5VbRhGFuyKpdUR
Recommendations
BACKGROUND
Summary
Mammography is an important tool in reducing the number of deaths … between the ages of 40 to 49 years may reduce the risk of
dying of breast cancer, but the number of deaths
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www.uspreventiveservicestaskforce.org/uspstf/document/final-modeling-study/aspirin-to-prevent-cardiovascular-disease-preventive-medication
April 26, 2022 - 23 The model includes a CRC module capable of assessing primary prevention of either CRC cases or deaths … MI, combined nonfatal CVD events (nonfatal congestive heart failure, ischemic stroke, and MI), CVD deaths … (excluding those due to intracranial hemorrhage), CRC incidence, CRC deaths, and harms related to fatal … However, the model did account for CVD deaths that were indirectly prevented or delayed because of the … GI bleeds
GI bleed deaths
ICH
ICH deaths
Net QALYs
Net life-years
Net events prevented
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-screening-for-breast-cancer/breast-cancer-screening-january-2016
January 11, 2016 - per 10,000 women over 10 years); 0.86 for those aged 50 to 59 years (CI, 0.68 to 0.97) (7 trials; 8 deaths … The long case accrual method counts all breast cancer cases contributing to breast cancer deaths. … The short case accrual method includes only deaths that occur among cases of breast cancer diagnosed … The number of deaths reduced (i.e., prevented) was 2.9 (CI, –0.6 to 8.9) for women aged 39 to 49 years … The long case accrual method counts all breast cancer cases contributing to breast cancer deaths.
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www.uspreventiveservicestaskforce.org/uspstf/update-on-methods-insufficient-evidence---table-3
February 01, 2009 - cancers and 52,000 cases of melanoma are diagnosed each year in the United States. 23
About 11,000 deaths
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/2Wc3FRHpVDPX2jT_WzjEXX
July 31, 2020 - modeling on how
estimated life-years gained, colorectal cancer cases averted, and colorectal cancer deaths … at age 45 years may moderately increase life-
years gained and decrease colorectal cancer cases and deaths … per 100 000 American Indian/
Alaska Native adults, 13.6 deaths per 100 000 non-Hispanic White
adults … modeling on how estimated life-years
gained, colorectal cancer cases averted, and colorectal cancer deaths … at
age 45 y
Screening modality
and frequency
Stool tests
Benefit: Estimated No. of CRC deaths averted
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening-june-2016
June 15, 2016 - of persons who are screened because that will have the largest effect on reducing colorectal cancer deaths … shown that screening with the guaiac-based fecal occult blood test (gFOBT) reduces colorectal cancer deaths … Direct Visualization Tests
Several RCTs have shown that flexible sigmoidoscopy alone reduces deaths … also consistently estimate that combined testing yields more life-years gained and colorectal cancer deaths … The figure depicts the estimated number of life-years gained, colorectal cancer deaths averted, lifetime
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www.uspreventiveservicestaskforce.org/uspstf/update-on-methods-insufficient-evidence---table-5
February 01, 2009 - About 160,000 deaths per year are attributable to lung cancer.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Fbj5RkuC7VEsKFULEsfwUg
January 01, 2016 - Screening for Breast Cancer
Screening for Breast Cancer
The goal of screening is to reduce cancer deaths … • Mammograms also reduce breast cancer deaths in women ages 40 to 49 years. … it is not clear whether
this technology will result in improved health, quality of life, or fewer deaths … The Task Force found that regular screening every 2 years reduces breast
cancer deaths for women ages
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/vCzPVrVJfgFWfpWRdEHMKQ
July 01, 2012 - Seventy percent of deaths due to
prostate cancer occur after age 75 years (1). … The European trial found a reduction in
prostate cancer deaths of approximately 1 death per 1000
men … Even in the
“core” age group of 55 to 69 years in the ERSPC trial, only
462 of 17 256 deaths were due … Perioperative
deaths or cardiovascular events occur in approximately
0.5% or 0.6% to 3% of patients, … After 15
years of follow-up, the prostate cancer mortality rate was
18 deaths per 1000 person-years.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening
May 18, 2021 - patients to administer. 9 , 10 However, randomized trials demonstrate direct evidence of decreased deaths … at age 45 years may moderately increase life-years gained and decrease colorectal cancer cases and deaths … 100,000 Asian/Pacific Islander adults. 22 Colorectal cancer death rates in 2014 to 2018 were 18.0 deaths … per 100,000 Black adults, 15.1 deaths per 100,000 American Indian/Alaska Native adults, 13.6 deaths … per 100,000 non-Hispanic White adults, 10.9 deaths per 100,000 Hispanic/Latino adults, and 9.4 deaths