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  1. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label_executive.pdf
    January 01, 2007 - Layout 1 Background Aripiprazole, olanzapine, quetiapine, risperidone, and ziprasidone are atypical antipsychotics approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia and bipolar disorder. These drugs have been studied for off-label use in the following conditions: dementia and seve…
  2. effectivehealthcare.ahrq.gov/sites/default/files/reporting.ppt
    September 01, 2009 - There were no deaths reported in the three respiratory syncytial virus/severe bronchiolitis trials; thus … than PSA [prostate-specific antigen] testing and treated with radical prostatectomy experienced fewer deaths … from prostate cancer, marginally fewer deaths from any cause, and fewer distant metastases.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_disposition-comments.pdf
    August 12, 2016 - Omega-3 Fatty Acids and Cardiovascular Disease: An Updated Systematic Review Source: https://www.effectivehealthcare.ahrq.gov/search-for-guides-reviews-and-reports/ ?pageaction=displayproduct&productid=2261 Published Online: August 12, 2016 Evidence Report/Technology Assessment Disposition of Comments Report Re…
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_disposition-comments.pdf
    November 27, 2012 - with a 0.5% perioperative mortality (the largest series of patients with HCV infection found no deaths … “HCV infection… associated with an estimated 12,000 deaths each year in the United States.” … The largest study of HCV patients showed no deaths. … Mortality is 12,000 deaths per year. … in 2010 could reduce the risk of cirrhosis, liver decompensation, liver cancer, and liver related deaths
  5. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
    July 01, 2011 - perioperative death in about 1.5% in Surgery vs. control two studies of UPPP—though most studies reported no deaths
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
    August 05, 2010 - In the United States, there are an estimated 16,500 annual deaths due to NSAID-induced gastrointestinal
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/vaccine-safety_research-protocol.pdf
    September 18, 2012 - there were nearly 12,000 new cases of cervical cancer reported, with 4,000 cervical cancer-related deaths
  8. effectivehealthcare.ahrq.gov/sites/default/files/cer-221-copd-comments.pdf
    October 11, 2019 - CER 221 Disposition of Comments: Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD Comparative Effectiveness Review Disposition of Comments Report Research Review Title: Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD: A Sy…
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-comments_0.pdf
    October 11, 2019 - CER 221 Disposition of Comments: Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD Comparative Effectiveness Review Disposition of Comments Report Research Review Title: Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD: A Systematic Rev…
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_executive.pdf
    April 01, 2013 - 1 Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment: Comparative Effectiveness Update Executive Summary Background Anemia, a deficiency in the concentration of hemoglobin-containing red blood cells, is prevalent among cancer patients, depending on the type of malignancy and t…
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
    April 01, 2013 - placebo SOE = Insufficient (6 studies, 838 patients) Inconclusive benefit (few studies, few deaths … placebo SOE = Insufficient (4 studies, 1,011 patients) Inconclusive benefit (few studies, few deaths … monotherapy SOE = Insufficient (3 studies, 566 patients) Inconclusive benefit (few studies, few deaths … Few deaths were observed in these limited-duration studies, leading to wide confidence intervals and
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
    January 01, 2023 - Recent trends in cardiovascular disease deaths: a state specific perspective.
  13. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
    March 01, 2011 - new studies were generally of short duration (less than 1 year) and had few long-term events (such as deaths … We recommend that studies consistently report the number of deaths in each study arm, even if there were … Low Many RCTs were of short duration (less than 1 year) and had few deaths, limiting the precision of
  14. effectivehealthcare.ahrq.gov/products/outcomes-nutrition/protocol
    December 01, 2020 - Current Page Topic Timeline Nov. 30, 2020 Topic Initiated Dec. 1, 2020 Research Protocol Maternal and Childhood Outcomes Associated With the Special Supplemental Nutrition Program for Women, Infants and Children (WIC) Research Protocol December 1, 2020 Download Main Document PDF 484.1 KB This protoc…
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
    February 15, 2017 - is the leading cause of death for both men and women, heart disease accounts for more than 600,000 deaths … annually, or 23.5% of deaths from all causes.2 Over 25 million adults in the United States are currently … Deaths: Leading Causes for 2013. NVSR Volume 65, Number 2. 95 pp. (PHS) 2016-1250.
  16. effectivehealthcare.ahrq.gov/sites/default/files/ch_10-user-guide-to-ocer_130129.pdf
    January 01, 2011 - 135 Abstract This chapter provides a high-level overview of statistical analysis considerations for observational comparative effectiveness research (CER). Descriptive and univariate analyses can be used to assess imbalances between treatment groups and to identify covariates associated with exposure and/or the stu…
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief2-opioid-withdrawal.pdf
    April 01, 2021 - pain intensity in some patients, it is also associated with adverse effects, morbidity, and overdose deaths … Associations between stopping prescriptions for opioids, length of opioid treatment, and overdose or suicide deaths … coping with an opioid and substance use disorders crisis that involves shifting “waves” of overdose deaths
  18. Schwitzer_ECCS2012 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/schwitzer_eccs2012.pdf
    July 23, 2012 - Mount Sinai School of Medicine in [New York], said he thinks the new guidelines could cause unnecessary deaths
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
    April 20, 2015 - known that kidney cancer affects approximately 65,000 new patients each year with more than 13,000 deaths … most lethal, with approximately 35% of patients dying within 5 years of diagnosis.[8] However, the deaths … Given the increased incidence in early, low-stage tumors without improvement in cancer-related deaths
  20. effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
    October 30, 2012 - 71 Abstract This chapter provides an overview of considerations for the development of outcome measures for observational comparative effectiveness research (CER) studies, describes implications of the proposed outcomes for study design, and enumerates issues of bias that may arise in incorporating the ascertainme…

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