-
effectivehealthcare.ahrq.gov/products/dietary-supplements/research-protocol
December 21, 2010 - Outcomes
KQ 1
Clinical outcomes:
Mortality
All-cause mortality
Vascular death
Specific vascular … death (e.g., fatal MI, fatal stroke)
Ischemic Heart Disease (Coronary Artery Disease)
All myocardial … coronary syndrome
Coronary artery disease composite outcomes (combination)
Arrhythmias
Sudden death … Methods Guide35 (for definitions, please see Section VI):
KQ 1: Mortality (all-cause and vascular death
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_executive.pdf
April 01, 2013 - stressor may include having
direct personal experience of an event
that involves actual or threatened death … or serious injury or other threat to one’s
physical integrity; witnessing an event
that involves death … or a threat to
the physical integrity of another person;
or learning about unexpected or violent
death … , serious harm, or threat of death or
injury experienced by a family member
or other close associate
-
effectivehealthcare.ahrq.gov/products/atrial-fibrillation/research-protocol
January 27, 2012 - Not only is the risk of death in patients with AF twice that of patients without AF, but AF can result … The primary end point was a composite of death from cardiovascular causes, hospitalization for heart … Follow-Up Investigation of Rhythm Management (AFFIRM) trial—showed a trend toward a higher risk of death … rate control as an initial strategy with adequate anticoagulation therapy might be enough to prevent death
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
December 15, 2010 - www.effectivehealthcare.ahrq.gov
Published Online: April 28, 2011
Page 11 of 26
o All-cause mortality
o Vascular death … o Specific vascular death (e.g., fatal MI, fatal stroke)
• Ischemic Heart Disease (Coronary Artery … syndrome
o Coronary artery disease composite outcomes (combination)
• Arrhythmias
o Sudden death … Methods Guide35 (for
definitions, please see Section VI):
KQ 1: Mortality (all-cause and vascular death
-
effectivehealthcare.ahrq.gov/sites/default/files/clinical-pathway-methods-report-appendix-k.pdf
February 01, 2018 - complicated by toxic megacolon, admission to intensive care for
severe sepsis, requirement for surgery, or death … toxin effects and shock, resulting in need for intensive care unit (ICU)
admission, colectomy, or death … difficile infection can lead to pseudomembranous colitis, sepsis, toxic
megacolon, colonic rupture, and death … The risk of death increases in patients
with multiple comorbidities.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-update_research-protocol.pdf
August 18, 2016 - disturbance,
gastrointestinal symptoms, elevated blood pressure, increased heart rate, risk of sudden cardiac … death, cardiac arrhythmias, conduction abnormalities, tics or other movement disorders, behavior
changes … death, cardiac arrhythmias,
conduction abnormalities, tics or other movement disorders, behavior changes … death
• Cardiac arrhythmias
• Conduction abnormalities
• Tics or other movement disorders
• Behavior … death
o Cardiac arrhythmias
o Conduction abnormalities
o Tics or other movement disorders
o Behavior
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/respectful-maternity-care-protocol.pdf
September 16, 2022 - Background
Despite sizeable resources invested in US maternity care, severe maternal morbidity
and death … successfully reach populations facing barriers and could
address the diversity of contributors to maternal death
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
May 01, 2013 - capacity and quality of life
as well as an increased risk for myocardial
infarction (MaI), stroke, and death … adverse cardiovascular events (e.g., all-
cause mortality, myocardial infarction, stroke,
cardiovascular death … cardiovascular events (e.g., all-cause mortality,
myocardial infarction, stroke, cardiovascular
death … including cardiovascular
events (e.g., all-cause mortality, myocardial
infarction, stroke, cardiovascular death … outcomes were considered: cardiovascular events, (e.g.,
all-cause mortality, MI, stroke, cardiovascular death
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes.pdf
April 01, 2005 - • Cardiovascular related
death was the most
frequent reported cause
• 5 -year
mortality
ranged … events 13% and
strokes 13% over 3-54
months (1 study)
• CVD stop point
(including
hypertension, death … 9%, strokes
4%, and MI 4% over
3-54 months (1 study)
• CVD stop point
(including hypertension,
death … Percent
stenosis and baseline
kidney function were f
predictors of death (or
dialysis) in separate … Other
variables related to
cardiovascular disease
were also found to
predict death. 1 study
found
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
October 10, 2019 - of brain metastases may have
substantial prognostic implications by causing neurologic symptoms or death … necrosis, fatigue, seizures, vomiting
(KQ 1-3)
(KQ 4)
Final Health Outcomes
Survival
Death … However, if not specified, we will apply the FDA definition of serious adverse events
(death, life-threating … Overall survival (time to death, hazard ratio)
2.
-
effectivehealthcare.ahrq.gov/products/autism-update/consumer
September 23, 2014 - care of a doctor, these products can cause serious harm, including dehydration, kidney failure, and death
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_consumer.pdf
January 01, 2017 - ��Taking more colchicine than prescribed can
lead to overdose and death.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-update_consumer.pdf
September 01, 2014 - care of a doctor, these products can cause
serious harm, including dehydration, kidney failure, and death
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_consumer.pdf
September 01, 2016 - hopeless, helpless, worthless, or guilty
�Avoid being with people
�Have thoughts about your own death
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_clinician.pdf
August 01, 2016 - CIN (e.g., hypersensitivity reactions,
need for renal replacement therapy, cardiovascular events, death
-
effectivehealthcare.ahrq.gov/products/vitamin-d-calcium/research-protocol
June 10, 2013 - events or symptoms
Cerebrovascular events
Peripheral vascular events or symptoms
Cardiovascular death … ischemic attacks]; peripheral vascular events or symptoms [diagnosis; claudication]); cardiovascular death
-
effectivehealthcare.ahrq.gov/products/opioid-use-disorder/research-protocol
February 29, 2016 - Overdose Death Rates. … February 2015; https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates .
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-use-disorder_research-protocol.pdf
February 24, 2016 - Overdose Death Rates. … February 2015; http://www.drugabuse.gov/related-topics/trends-
statistics/overdose-death-rates.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-205-predictors-trauma-care-disposition-comments.pdf
April 01, 2018 - Including demonstrating that
SBP<110 are associated with increased incidence of death, and sub
populations … Hypotension (SBP<90) will be more
sensitive for the composite outcomes like RC (includes death,
operative
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
June 01, 2013 - Obstructive
Pulmonary Disease Exacerbations
Key Facts: COPD is the third most common cause of death … Exacerbations
Unmet need: Chronic obstructive pulmonary disease (COPD) is the third most common cause
of death … Unmet need and health outcomes: No cure exists for COPD, the third leading cause of death
and a significant