-
effectivehealthcare.ahrq.gov/sites/default/files/back.pdf
January 01, 2011 - patients and
families wrestling with complex medical
decisions, finding a way to
approach
death … www.effectivehealthcare.ahrq.gov/index.cfm) �
o Therapy to prepare for death
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_surveillance.pdf
August 01, 2012 - Hyperglycemia and death in cystic fibrosis-
related diabetes. … (adjusted HR
4.05, 1.15, 14.28,
p=0.03) or 3-year
risk of death
(unadj. … Death was
associated with
body mass index
<19 (adjusted
HR1.52, 95% CI
1.10, 2.10,
p=0.011); use … Participation in
registry
Retrospective cohort
study
Risk factors
associated with death
in CF … Most
common cause of
death was CNS
tumor (recurrence
or new onset). 11%
of deaths were
judged
-
effectivehealthcare.ahrq.gov/sites/default/files/jensen_eccs2012.pdf
January 01, 2012 - to manage patient communication
Slide 9: Future Research Questions
and Courses
of Action
• Death
-
effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-apf2_0.xlsx
January 01, 2018 - NR NR NR NR NR NR NR NR
Clegg, 2006 Good OA (knee) NSAID Celecoxib 200 mg/d 24 Short 7 318 NR NR CV death … NR NR NR NR NR NR NR NR NR NR
Clegg, 2006 Good OA (knee) Placebo Placebo 24 Short 11 313 NR NR CV death … NR NR NR NR NR NR
Silverstein, 2000 Good Mixed Diclofenac 150 mg/d 26 Intermediate NR NR NR NR CV death … NR NR NR NR NR NR
Silverstein, 2000 Good Mixed Ibuprofen 2400 mg/d 26 Intermediate NR NR NR NR CV death … NR NR NR
Nissen, 2016 Fair Mixed Celecoxib 200 to 400 mg/d (mean 209 mg/d) 80 Long NR NR NR NR CV death
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
February 01, 2013 - There were no incidences of in-hospital
complications of coronary artery bypass grafting (CABG)
or death … The FFR group also displayed a significant decrease in
the composite outcome of death and MI at both … For the composite
outcome of MACE (defined as death, MI, and target lesion
revascularization) in this … which
coronary lesions require intervention would confer a
lower risk of the combined endpoint of death … The 1-year composite outcome of death, MI, and ischemia-driven
target vessel revascularization was not
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
May 01, 2012 - Antipsychotic Use and Risk of Sudden Cardiac Death by Cardiovascular
Risk Score .................. … Antipsychotics and the risk of sudden
cardiac death. Arch Gen Psychiatry
2001;58:1161-67.
24. … Antipsychotic use and risk of sudden cardiac death by cardiovascular risk score
Cardiovascular Disease … Antipsychotics
and the risk of sudden cardiac death. … Cyclic antidepressants and the
risk of sudden cardiac death.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/lysosomal-storage-diseases-therapies_research-protocol.pdf
November 15, 2012 - Life expectancy is <
10 years, with cause of death most commonly due
to obstructive airway disease, … Life expectancy ranges from 10-20
yrs, with cause of death usually due to heart
disease, from valvular … Life expectancy is 40 - 50 yrs, with cause of death
usually due to a decline in kidney function or to … Life expectancy is <1 yr, with cause of death usually
from cardiorespiratory failure or respiratory … Life expectancy is
variable, depending on severity and rate of disease
progression, with cause of death
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
June 01, 2012 - In Revascularization + medical therapy versus medical therapy, the HR for death was
0.90 with 95% CI … The HR for overall death was 0.99 with 95% CI= 0.30, 3.24
b. … The HR for Primary end point or death was 0.81 with 95% CI= 0.42, 1.56
8 1 Signal
3. … medical therapy
Death:
HR= 0.90; 95% CI= 0.69, 1.18; p =
0.46
1 Signal
Medical vs. … In other words the reduction in the risk of death has
moved from 30% to 10%.
-
effectivehealthcare.ahrq.gov/sites/default/files/ahrq_community_forum_webinar_sadwin.pdf
January 01, 2011 - AHA Branded Light Template
Partnering with Patients to
Disseminate Research Products
Lawrence Sadwin
October, 13 2011
Partnering with Patients to
Disseminate Research Products
• Relationships with patient and
consumer organizations create
channels for disseminating results
• Establishing trust…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_executive.pdf
September 01, 2011 - :
Key Question 1: improve neonatal health outcomes,
including bronchopulmonary dysplasia, neonatal
death … , death within initial hospitalization, significant
intraventricular hemorrhage (grade III/IV),
necrotizing … , death within initial hospitalization, and maternal
withdrawal due to adverse effects (Withdrawal-AE … the strength of evidence
favoring the SQ terbutaline pump compared with oral
tocolytics for neonatal death … Infant mortality statistics
from the 2006 period linked birth/infant death data set.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
February 01, 2008 - treatment is to target
the men most likely to need intervention in
order to prevent prostate cancer death … Six months
of combination therapy reduced clinical failure,
biochemical failure, or death from any cause … • Death within 30 days of RP is approximately 0.5% in Medicare
recipients age 65 and over. … High • Higher Gleason histologic scores are associated with greater
risk of prostate-cancer-related death … PSA level Medium • The risk of prostate cancer death and disease progression or
recurrence is associated
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/angina-heart-attack-treatments_research-protocol.pdf
December 11, 2012 - patients with UA/NSTEMI involve the elimination of
ischemia and the prevention of adverse events (death … For the majority of patients who
are at higher risk of recurrent ischemia, MI, or death, an early invasive … or MI.8-11 For the minority of patients at low or
intermediate risk of recurrent ischemia, MI, or death … All-cause death
10
2. Cardiovascular disease-related death
3. Nonfatal MI
4. … o Cardiovascular-related death
o Nonfatal myocardial infarction
o Revascularization
o Stroke
o
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-196-evidence-summary-immunotherapy-asthma.pdf
March 01, 2018 - There was insufficient evidence to draw conclusions
regarding the effect of SCIT on anaphylaxis or death … • Serious adverse events such as anaphylaxis and
death were not reported in the included studies in … non-RCT20
1 case series21
1 case report22
N=792
55 cases
Likely
(Likelihood
of causality)
Death … case
reports41-43
2 Certain
1 Likely
(Likelihood of
causality)
Unable to draw
conclusions
Death … low, 1
medium,
1 high)
Consistent Direct Precise Undetected SLIT does not
increase the risk
of death
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-evidence-summary.pdf
June 01, 2021 - of brain metastases may have substantial prognostic
implications by causing neurologic symptoms or death
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ischemic-stroke-treatment_research-protocol.pdf
February 19, 2010 - Technical Brief
Definition and Prevalence of Ischemic Stroke
Stroke is the third leading cause of death … , 43.6 deaths occurred due to stroke per 100,000 people in
the Unites States, averaging out to one death … that at-risk patients view the consequences of
experiencing an ischemic stroke as being worse than death … downstream brain region.13 If blood flow is not restored to the affected area, ischemia and
eventual cell death … Compressed Mortality File: Underlying Cause of Death, 1979-2005.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
November 01, 2013 - The other mortality outcomes (i.e.,
cardiac and sudden cardiac death) demonstrated less
convincing … Sudden cardiac death had increasing HRs across the
quintiles of NT-proBNP and an adjusted HR = 1.9 ( … Multimarker
strategy for the prediction of 31 days cardiac death in patients
with acutely decompensated … Use of multiple
biomarkers to improve the prediction of death from
cardiovascular causes. … N-terminal pro-
B-type natriuretic peptide is associated with sudden cardiac
death risk: the Cardiovascular
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0136_07-21-2009.pdf
January 01, 2009 - including sexual function), and
patient satisfaction; for surgical procedures, risk of complication and death
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_overview.pdf
June 24, 2014 - respect to the rate of the composite primary
end point or any of its individual components, including death
-
effectivehealthcare.ahrq.gov/sites/default/files/web-based_willis_respondent.pdf
January 01, 2009 - • Death
panel
versus
informed
decision-‐making
o No
one
wants
to
die
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-2.pdf
February 01, 2018 - in
meta-analyses
- More likely to be consistent
even with differing baseline
risks
- Values of “death … rather than an assessment of
appropriateness
- Preferred if switching from event and non-
event (e.g. death … being reciprocal for events and non-
events.
► Thus, if switching from event and non-event (e.g., from death