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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer18-heart-disease-ace-inhibitor-arb-executive.pdf
October 01, 2009 - Layout 1
Background
Nearly 2,400 Americans die of
cardiovascular disease each day, an average
of one death … cardiovascular disease has accounted
for more deaths than any other single cause
or group of causes of death … Low • ARB therapy (telmisartan) may not reduce the composite
efficacy endpoint of cardiovascular death … Low • ARB therapy (telmisartan) impacts the composite efficacy
endpoint of cardiovascular death, nonfatal … ACE inhibitor therapy (perindopril, ramipril) reduces
composite efficacy endpoints (cardiovascular death
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes-2007.pdf
January 01, 2007 - or kidney function worsening (by GFR, SCr, or dialysis), or atherosclerotic cardiovascular event, or death … aneurysm
1%
Access site
occlusion 0.3%
Severe access
site bleeding 2%
30 d mortality 0.6%
Death … from tubular necrosis
and multiorgan failure 0.7%
Death from GI hemorrhage
after stent implant while … after lower limb
cholesterol
embolization 1%
Death after thrombosis
of aortofemoral
prosthetic … Brachial artery occlusion
1%
Subacute stent
thrombosis after 3 d 1%
Groin hematoma 5% Ischemic cardiac
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-264-maternal-morbidity-mortality-executive-summary.pdf
December 01, 2023 - geographically, reported:
o Income inequality was associated with a 14 percent increase in excess risk
of death … care than any other country, the United States
has seen maternal deaths rise since 2000, and risk of death … for pregnant women, income inequality
was associated with a 14 percent increase in excess risk of death … Psychosocial
risk factors as contributors to pregnancy-
associated death in Virginia, 1999-2001.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_appendixes.pdf
January 01, 2009 - Glucose tolerance and insulin
secretion, morbidity, and death in patients with cystic fibrosis. … Until death
or Dec 1984
Student’s t test
or Chi-square
test and Cox
proportional
hazards model … Until death
or transplant
by Dec 31,
1990
Cox proportional
hazards model
FEV1 at
baseline … Risk of death in
cystic fibrosis patients with severely
compromised lung function. … Risk factors for death of patients with cystic
fibrosis awaiting lung transplantation.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/suicide-prevention_research.pdf
October 01, 2016 - and 20-24 age groups have increased since 2007.1 In 2014, suicide was the second leading
cause of death … data dictionaries limits our ability to say which databases are useful,
only the National Violent Death … x
6 Death records 3 Y/N/? x
6 Healthcare provider records (e.g., EHRs) 3 Y/N/? … , Near Death and Stillbirth Commission
(CDNDSC) Delaware Child Death Review
Delaware Health and Social … with Dignity Act Database
Oregon Health Authority Oregon Death Data
Oregon Health Authority - Public
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-foot-ulcer-amputation-incidence_research.pdf
January 01, 2011 - Many re-
searchers have reported an increased in-
cidence of death among LEA patients. … examines
microvascular and macrovascular compli-
cations associated with diabetes, as well as
the death … The rate of death among dia-
betic Medicare FFS beneficiaries with an
incident diabetic foot ulcer ( … For this purpose,
beneficiaries were considered alive up
to and including the month of their
death … Beneficiary death dates were obtained
from the EDB.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
October 18, 2010 - within initial hospitalization, neonatal death)
• Secondary outcomes
Gestational age at delivery, … within initial hospitalization and neonatal death, for the following subgroups:
a. women <28 +0 weeks … within initial
hospitalization
• Neonatal death
Maternal Side Effects
• Pulmonary edema … within initial hospitalization
• Neonatal death
Outcomes –
other health
• Gestational age … and/or death within initial hospitalization; and,
maternal withdrawal due to adverse effects (WDAE)
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/mmm-draft-protocol-amendment.pdf
February 02, 2022 - long-term health problem resulting from
pregnancy and childbirth,1 and maternal mortality refers to the death … care than any other country,
the United States has seen maternal deaths rise since 2000, and risk of death … Additionally, the rates of
incarceration, illness, and death are greater among BIPOC than white mothers … Outcomes Postpartum health status outcome such
as pregnancy-related or pregnancy-
associated death, … Maternal
morbidity and risk of death at delivery hospitalization.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment_research-protocol.pdf
September 29, 2011 - Objectives for the Systematic Review
Overview
Cardiovascular disease remains the leading cause of death … cardiovascular disease each year, exceeding the number of
deaths in men and the next seven causes of death … This translates into
approximately one death every minute.
1,2
Coronary artery disease (CAD), which … The first is to prevent MI and death
and thereby increase the quantity of life. … of PCI to optimal medical therapy reduced the
prevalence of angina but not the long-term rates of death
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
September 01, 2009 - and risks
of these two options in terms of clinical events (e.g.,
myocardial infarction, stroke, or death … Evidence Synthesis
Primary outcomes were all-cause mortality and vascular
death. … on harms and clinical outcomes,
other than the primary outcomes of all-cause mortality
and vascular death … three trials, one of which was a large trial
lasting 5 years of 18,645 Asians.
4
5
Vascular death … Treatments aimed at modifying lipids might be
expected to lower the rates of death due to vascular
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_surveillance.pdf
January 30, 2013 - Key Question 1: improve neonatal health outcomes, including bronchopulmonary dysplasia,
neonatal death … , death within initial hospitalization, significant intraventricular hemorrhage (grade
III/IV), necrotizing … Key Question 1: improve neonatal health outcomes, including bronchopulmonary dysplasia, neonatal death … strength of evidence
favoring the SQ terbutaline pump
compared with oral tocolytics for
neonatal death … In other words the reduction in the risk of death has
moved from 30% to 10%.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_surveillance.pdf
January 30, 2013 - Key Question 1: improve neonatal health outcomes, including bronchopulmonary dysplasia,
neonatal death … , death within initial hospitalization, significant intraventricular hemorrhage (grade
III/IV), necrotizing … Key Question 1: improve neonatal health outcomes, including bronchopulmonary dysplasia, neonatal death … strength of evidence
favoring the SQ terbutaline pump
compared with oral tocolytics for
neonatal death … In other words the reduction in the risk of death has
moved from 30% to 10%.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-253-maternal-child-outcomes-wic-executive-summary.pdf
April 01, 2022 - SOE: Low), no difference in smoking during or after
pregnancy (SOE: Low), no difference in perinatal death … delivery, weight status, healthcare utilization,
health behaviors), neonatal birth outcomes (fetal death … risk of infant low birth weight (2 studies)
May be associated (Low SOE)
• No difference in perinatal death
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-outcome-measure-harmonization-depression.pdf
November 01, 2020 - Lastly, the death from suicide measure was updated to include additional International
Classification … Death may not be recorded in the
EHR, and, even when the date of death is recorded, information on the … cause of death may not be
readily available. … In addition, in cases of suicide, a different cause of death may be listed because
of the perceived … While death from suicide is important to measure, it is equally
important to ensure that all necessary
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-lumbar-spondylolisthesis.pdf
March 01, 2021 - Where this is not possible (e.g., cause of death), the logic requires an asserted
relationship. … Spondylolisthesis
Outcome Measures
OMF
CATEGORY
OUTCOME
MEASURE DEFINITION
Survival All-cause death … at 30 days All-cause death within 30 days of treatment. … Collect cause of death when possible.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-lumbar-spondylolisthesis.pdf
March 01, 2021 - Where this is not possible (e.g., cause of death), the logic requires an asserted
relationship. … Spondylolisthesis
Outcome Measures
OMF
CATEGORY
OUTCOME
MEASURE DEFINITION
Survival All-cause death … at 30 days All-cause death within 30 days of treatment. … Collect cause of death when possible.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth-disposition-121205.pdf
September 07, 2012 - the Combs paper and the
general need for larger datasets to assess
harms such as IUFD and neonatal death … In this study,
the intrauterine fetal death rate was only
reported in combination with the miscarriage … The safety signal
uncovered by the FDA was an excess of fetal death in patients
exposed to 17P. … We do not
provide a meta-analysis for fetal death but do
consider the precision across studies. … ,
birth weight, fetal neonatal death, etc.
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
September 21, 2012 - deviation of the
outcome in each trial arm; when the outcome
is the occurrence of an event (e.g., death … Example study size table for an RCT comparing the risk of death for
two alternative therapies*
Scenario … Risk of death associated with use of conventional
versus atypical antipsychotic drugs among elderly … Risk of
death in elderly users of conventional vs. atypical
antipsychotic medications.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/diagnostic-error-executive-summary.pdf
August 01, 2023 - incorrect diagnosis, 1 in 50 suffering an adverse event, and 1 in 350
suffering permanent disability or death … 95% CI 1.0 to 3.6), serious misdiagnosis-related harms (i.e., permanent, high-severity
disability or death … For each misdiagnosis-related death, it is estimated that there are
roughly 0.41 (PR 0.27 to 0.60) ED
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_surveillance.pdf
May 01, 2013 - Rates of death and myocardial
infarction were not statistically different
between groups. … disease were randomized to
CABG or PCI with drug-eluting
stents
1900 The composite outcome of death … randomized
to CABG or PCI, initially bare
metal stents but later drug-eluting
stents
510 The rate of death … artery disease
were randomized to CABG or PCI
with drug-eluting stents
600 The composite rate of death … artery disease
were randomized to CABG or PCI
with drug eluting stents
201 The combined rate of death