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effectivehealthcare-admin.ahrq.gov/products/methods-guidance-harms/methods
May 01, 2020 - most useful for evaluating serious harms that are more reliably reported and recorded (for example, death … 100,000 patients would have been needed in the COBALT or GUSTOIII trials to rule out an excess relative death … A systematic review of the risks of stroke and death due to endarterectomy for symptomatic carotid stenosis … Serious adverse event
Any adverse event with serious medical consequences, including death, hospital … For example, a rash could be "severe" but not "serious" (i.e., not resulting in death, hospital admission
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
September 01, 2012 - ultimate goal in preventing
preterm birth is to eliminate the risks of
neonatal complications and death … In these
same trials, the risk of neonatal death was 4.0 percent
among women in the placebo group and
-
effectivehealthcare-admin.ahrq.gov/products/safety-vaccines/protocol
January 01, 2021 - event will be graded for severity on a five-point scale, with grade 1 being mild and grade 5 being death … adults): Acute disseminated encephalomyelitis, anaphylaxis or systemic allergic reaction, angioedema, death … seizures, stroke, transverse myelitis, diabetes
Key outcomes for KQ 3 (pregnant women): Birth defects, death … Fetal death and preterm birth associated with maternal influenza vaccination: systematic review. … Influenza vaccination during pregnancy: a systematic review of fetal death, spontaneous abortion, and
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effectivehealthcare-admin.ahrq.gov/products/mental-health-pregnant/protocol
October 01, 2023 - symptoms or condition a Parent-infant bonding a , b Suicide a ,b Suicidal thoughts a Attempted suicide a Death … Fetal/neonatal/pediatric clinical outcomes Live birth Infant feeding success Infant growth Pediatric death … Modifiers Pregnancy status (pregnant, postpartum after live birth, postpartum after fetal loss or infant death … various nonpharmacological interventions Relative impact on suicidal thoughts, attempted suicide, or death
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
January 30, 2020 - event will be graded for severity on a five-point scale, with grade 1
being mild and grade 5 being death … adults): Acute disseminated encephalomyelitis,
anaphylaxis or systemic allergic reaction, angioedema, death … seizures, stroke, transverse myelitis, diabetes
• Key outcomes for KQ 3 (pregnant women): Birth defects, death … Fetal death and preterm birth associated with
maternal influenza vaccination: systematic review. … Influenza vaccination during pregnancy: a
systematic review of fetal death, spontaneous abortion, and
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/vaccines-safety-protocol-130325.pdf
September 18, 2012 - other parental concerns about childhood vaccines
include links to multiple sclerosis, sudden infant death … self-care ADL
Grade 4: Life-threatening consequences; urgent intervention indicated
Grade 5: Death … 25, 2013
Adverse event Vaccine type
Constipation Below severity threshold
Crohn’s disease MMR
Death
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effectivehealthcare-admin.ahrq.gov/products/nephropathy-contrast-induced/research
January 01, 2020 - One study comparing different LOCMs investigated the outcomes of death and adverse events, and found
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effectivehealthcare-admin.ahrq.gov/products/autism-update/clinician
December 01, 2019 - medical supervision, these products can cause serious harm, including dehydration, kidney failure, and death
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effectivehealthcare-admin.ahrq.gov/products/high-cholestorol-medicines-update/research-protocol
December 01, 2019 - Rosuvastatin
Simvastatin
Outcomes
Clinical outcomes:
All-cause mortality and vascular death … the study investigator
SAEs as defined by the study investigator (e.g., an event that results in death … Outcomes
Clinical outcomes
All-cause mortality
Vascular death
Fatal MI, nonfatal MI, any … independently grade the strength of evidence on key outcomes—including, all-cause mortality, vascular death
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - In addition, the death rate from
cardiovascular disease in adults with type
2 diabetes is two to four
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_appendixes.pdf
January 01, 2006 - from
AMI, or sudden
death from
coronary heart
disease (CHD)
(Adjusted RR;
95% CI)
Graham 2005 … in phone
interview and 23%
reported using cc aspirin
Acute MI
requiring
admission or
sudden cardiac … death
Appendix F. … (C)
Death OR
recurrent HF
(Primary
outcome)
Appendix F. … CV death rate was 0.2% for both rofecoxib and
naproxen.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
April 20, 2015 - 40% of all kidney cancers.[6, 7]
Interestingly, despite this increase in early-stage cancers, the death … management or medications only
§ Major: requiring intervention, resulting in permanent disability or death … management
or medications only
o Major: requiring intervention,
resulting in permanent disability
or death
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/s66.pdf
October 01, 2007 - the date when the
selection criteria were met to the end of the study (December
31, 2004), date of death … An episode of use ended
on the date of death, loss of enrollment, diagnosis of serious
illness, stopping … 2007 Adherence to and Persistence on DMARDs
© 2007 Lippincott Williams & Wilkins S75
and sudden cardiac … death in patients treated with cyclo-oxygenase 2
selective and non-selective non-steroidal anti-inflammatory … Oral erythromycin use and the
risk of sudden cardiac death. N Engl J Med. 2004;351:1089–1096.
36.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
January 01, 2012 - insufficient
• BB significantly reduced risk of all-cause mortality, CHF hospitalizations, and
CHF death
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/home-based-care_research-protocol.pdf
November 19, 2014 - to provide care for
an indefinite period; until admission
to an institution, change in status,
or death … period until admission to an
institution, change in status that makes HBPC no longer appropriate, or
death … Patient and Caregiver Experience
• Quality of life
o Time patient remains in home and/or location of death … /death at home if
that is patient preference
o Patient and caregiver burden and/or anxiety
• Patient
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effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1406.pdf
February 01, 2015 - researchers hypothesize that neurofibrillary tangles adversely affect
neuron function and lead to cell death … Additional research implicates inflammation as a potential
trigger of progressive neuron death that … Recent data from the National Center for Health Statistics places
AD as the sixth-leading cause of death
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cerebral-palsy-feeding_disposition-comments.pdf
March 20, 2013 - Page 3, line 16-17: Indeed, chronic pulmonary disease
related to aspiration is the leading cause of death … Page 1 line 46-7: please change “suffer with” to are
affected by”
Page 3 line 17: leading cause of death … We have made these suggested edits and added
references for statements about cause of death.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diabetes-drugs-utilization_research.pdf
March 01, 2011 - Effect of rosiglitazone on the risk of myocardial infarction
and death from cardiovascular causes. … Risk of acute myo-
cardial infarction, stroke, heart failure, and death in elderly Medicare patients
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/what-is-the-comparative-effectiveness-of-conventional-ct-mdct-including-virtual-ct-bronchoscopy-petpet-ct-and-mri-for-the-diagnosis-or-pretreatment-staging-of-small-cell-and-non-small-cell-lung-cancer
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effectivehealthcare-admin.ahrq.gov/products/nv-hap/protocol
November 01, 2024 - incidences monthly. 12 In addition, NV-HAP is one of the outcomes included in the quality measure, Death … Centers for Medicare & Medicaid Services Measures Inventory Tool: Death Rate among Surgical Inpatients