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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_disposition-comments.pdf
November 27, 2012 - will successfully eradicate
virus and reduce their risk for later complications of liver disease or death … However, conducting a study that follows
patients from screening to illness and death is not feasible … In 2008 chronic liver
disease was the 12th leading cause of death in the United States
(www.cdc.gov … We have a very short window period to address this
epidemic before the death rate triples and we have … point in that diagnostic liver biopsies are invasive and associated with
serious harms and rarely death
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/long-term-care-adults-future_research.pdf
July 01, 2013 - anxiety), quality of life, social function, satisfaction, outcomes related to family caregivers,
death … , place of death, use of acute care services (e.g., hospitals, emergency departments), and
harms such … Need to deal with attrition, particularly attrition due to death. … o Modeling death as worst functional case or using two-stage models. … How should attrition be dealt with, particularly attrition due to death?
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effectivehealthcare-admin.ahrq.gov/products/risk-cardiovascular-disease/protocol
December 01, 2023 - in mortality rates in the last few decades, 1-3 cardiovascular disease remains the leading cause of death … The Leading Causes of Death in the US for 2020.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/long-term-care-adults_executive.pdf
November 01, 2012 - anxiety), quality
of life, social function, satisfaction, outcomes related to
family caregivers, death … , place of death, use of acute care
services (e.g., hospitals, emergency departments), and
harms (e.g … attitudes
Attrition bias • Attrition bias was often ignored • Methods to deal with attrition, especially death … :
– Use death as worst functional case
– Use two-stage models
Dealing with change in care
setting
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
September 30, 2015 - Retrospective cohort study
Oregon Medicaid beneficiaries' claims databased, linked PDMP database, and death … to index date (with ≥1 within 90 days prior to index date); <2 NRS pain scores in followup period; death
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
November 01, 2008 - most useful for evaluating serious harms that are more reliably reported and recorded (for
example, death … patients would have been needed in the COBALT or GUSTOIII trials to rule out an excess
relative death … A
systematic review of the risks of stroke and
death due to endarterectomy for
symptomatic carotid … Serious adverse event Any adverse event with serious medical consequences, including death, hospital … For example, a rash could be “severe” but not “serious” (i.e., not resulting in
death, hospital admission
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
November 01, 2008 - most useful for evaluating serious harms that are more reliably reported and recorded (for
example, death … patients would have been needed in the COBALT or GUSTOIII trials to rule out an excess
relative death … A
systematic review of the risks of stroke and
death due to endarterectomy for
symptomatic carotid … Serious adverse event Any adverse event with serious medical consequences, including death, hospital … For example, a rash could be “severe” but not “serious” (i.e., not resulting in
death, hospital admission
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rfviia.pptx
May 01, 2010 - pageaction=displayproduct&productID=450
Direct outcomes:
Clinical endpoints: death, functional status … measure but are not always closely connected to patient status)—to direct clinical endpoints such as death … Usual Care
Trauma is the leading cause of death in young men between the ages of 15 and 40. … Hemorrhage is the leading cause of early death (within 24–48 hours) in trauma and second only to traumatic … Transfusions result in pulmonary morbidity and death after a moderate degree of injury.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/rfviia.pptx
May 01, 2010 - pageaction=displayproduct&productID=450
Direct outcomes:
Clinical endpoints: death, functional status … measure but are not always closely connected to patient status)—to direct clinical endpoints such as death … Usual Care
Trauma is the leading cause of death in young men between the ages of 15 and 40. … Hemorrhage is the leading cause of early death (within 24–48 hours) in trauma and second only to traumatic … Transfusions result in pulmonary morbidity and death after a moderate degree of injury.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-research-executive-summ.pdf
March 01, 2025 - gastrointestinal; SBP = systolic blood pressure; SOE = strength of evidence;
SUID = sudden unexpected infant death
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effectivehealthcare-admin.ahrq.gov/products/retention-strategies-opioid-use-disorder/rapid-research
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
April 01, 2013 - right ventricular pressure overload,
dysfunction, and ultimately right heart
failure and premature death … echocardiography or biomarkers to assess the severity
of PAH, to predict events such as lung transplantation
or death … Twenty-three studies evaluated hazard
ratios (HR) for death, two studies evaluated HR for a
composite … outcome of death or lung transplant, and one
study evaluated HR for lung transplant alone.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_2012-12-10.pdf
January 01, 2012 - National Center for
Health Statistics, in the United States in 2005, AD was the seventh-leading cause of death … overall
and the fifth-leading cause of death in people 65 years of age and older. … Neurofibrillary tangles may cause cell dysfunction and
eventually cell death. … Other researchers point to inflammation as a possible cause of the progressive
cell death seen in the
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/dementia-nursing-home-characteristics_research-protocol.pdf
November 03, 2011 - caregivers, health systems, and society.
1
In 2006, Alzheimer’s disease was the
seventh-leading cause of death … It was the fifth-
leading cause of death for Americans ages 65 years or older.
1
Almost 11 million … high levels of stress,
exhaustion, anxiety, and depression and are at a higher risk for illness and death … residential LTC setting until the
end of a study, the time of permanent transfer to another setting, or death … long-term
care setting until the end of a study,
the time of permanent transfer to
another setting, or death
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
October 01, 2012 - Accomplish trial.23
They were followed for 3
years and found doubling
in serum creatinine,
ESRD or death … total
protein to predict patient
outcomes and found no
significant difference
between the two for
death … goals
1414 Subset of black patients in
ACCOMPLISH trial
Doubling in serum
creatinine, ESR or death … 3 years Doubling in serum creatinine, ESRD or death
was not different between Black and non-
Black … HRs were similar for total protein-
creatinine ratio and albumin-creatinine ratio
for all outcomes: death
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effectivehealthcare-admin.ahrq.gov/sites/default/files/reporting.ppt
September 01, 2009 - We only included trials if they reported death and number of days hospitalized or the number of days … combined randomized and nonrandomized groups when reporting outcomes, or if there were no outcome data on death
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
February 15, 2017 - Background and Objectives for the Systematic Review
Heart disease is the leading cause of death worldwide … .1 In the United States, where it is
the leading cause of death for both men and women, heart disease … Patients with depression post-MI have significantly increased risk of death.15
Despite the high prevalence … Black box warning for increased risk of death in elderly patients with dementia-related
psychosis.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
June 07, 2013 - OCs, by shifting the
incidence to younger ages, results in overall
decreased risk of in-hospital death … (3) If the cause of death is the same as the incidence
being studied (i.e., evaluating ovarian cancer … incidence and the cause of death is ovarian cancer-
related), then there should not be any bias. … If the
cause of death is different, then the bias would
depend on an unknown correlation.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/renal-update_executive.pdf
August 01, 2016 - with
better improvement in these outcomes, and worse kidney
function was associated with increased death … histories of cardiovascular disease were at increased
risk of adverse clinical outcomes, including death … edema, but not rapid kidney function decline or refractory
hypertension, was associated with increased death … with worse kidney function or with proteinuria
were at significantly increased risk of RRT but not death … medications and clinical outcomes, both of which found
a strong association between statin use and reduced
death
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_executive.pdf
January 01, 2011 - patient in the
TSAT group) due to bacterial pneumonia (at week 4 in the CHr group), sudden
death