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Total Results: 222 records

Showing results for "culture of safety".

121. DEcIDE 33: Summary Variables in Observational Resesarch: Propensity Scores and Disease Risk Scores (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
     May 01, 2012 - Different countries or different regions within countries may have local cultures and customs as to … A common question in pharmacoepidemiologic studies of drug safety is whether the risk conferred by a … Pharmacoepidemiology and Drug Safety 2008;17:546-555. … The comparative safety of rosuvastatin: a retrospective matched cohort study in over 48,000 initiators … Pharmacoepidemiol Drug Safety 2005;14(7):465-76.

122. Horizon-Scan Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-protocol.pdf
     December 01, 2011 - Potential Patient and Clinical Staff Safety Issues 17. … Patient Safety Issues (if applicable) 15. Required Resources 16. … Safety data that could change perspectives c. … Has a patient safety alert been issued that could signal a safety/efficacy change in perspectives? … [mh] 6 Organizational AND (“case studies” OR culture) 7 Combine sets #5 OR #6 8 New therapies

123. Weight-Loss-Surgery Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_executive.pdf
     June 01, 2013 - , or safety/adverse events; (2) nonsurgical studies with less than 1 year followup; (3) nonsurgical … Thus, we have almost no data on long-term efficacy and safety. … Diet, behavior, and culture in many of these locations may differ dramatically from that in the United … These additions did not change our conclusions regarding the effectiveness and safety bariatric surgery … Safety and efficacy of Roux-en-Y gastric bypass to treat type 2 diabetes mellitus in non-severely

124. #05 DEPRESSION (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - Results and Discussion of Comments Seven experts, with clinical, research, patient safety, and health … However, lack of safety and efficacy data from recent clinical trials led other experts to predict that … the brain, indicating a potential neurological biomarker of patient response.71,75 Safety information … Zealand, because the software will be sold in other countries whose adolescents may have different cultural … backgrounds and needs.

125. 08 Functional Limitations Potential High Impact 2012-12-10 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/08_functional_limitations_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - Overall, this device’s perceived complex nature, the existence of alternatives, and limited safety … of dimethyl fumarate because of the efficacy and safety profile reported in patients with RRMS. … Overall, this device’s perceived complex nature, the existence of comparators, and limited safety and … Neuroprotective effects of dimethyl fumarate and monomethyl fumarate on primary cultures of human … Neuroprotective effects of BG-12 and other fumarates on primary cultures of neurons and astrocytes

126. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_disposition-comments.pdf
     May 27, 2010 - Comments Report Research Review Title: Comparative Effectiveness and Safety of Radiotherapy Treatments … Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer. … The field frequently relies upon institutional observational series to assess efficacy and safety of … All of these phase II multi-institutional trials have confirmed the feasibility and safety of IMRT across … Comments Report Research Review Title: Comparative Effectiveness and Safety of Radiotherapy Treatments

127. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/12_pregnancy_potential_high_impact_2012-12-11.pdf
     January 01, 2012 - No statement in this report should be construed as an official position of AHRQ or of the U.S. … the case of new applications of already-diffused technologies. … milk from a source other than her own, only milk from a source that has been screened to ensure its safety … Overall, experts agreed that although more safety and efficacy studies must be performed to determine … Food and Drug Administration Center for Food Safety and Applied Nutrition; 2010 Dec 6. 6 p.

128. Disposition of Comments Report for The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
     September 29, 2014 - It provides an update on previous systematic reviews on the efficacy and safety of long-term opioids … their safety and efficacy. … and safety. … But, promoting a culture of fear of opioids could result in much more suffering. … their safety and efficacy.

129. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - No statement in this report should be construed as an official position of AHRQ or of the U.S. … the case of new applications of already-diffused technologies. … potential on the basis of experts’ comments and their assessment of potential impact. … Despite the safety and efficacy of emergency contraception (EC), its use remains low. … Despite its safety and efficacy, EC use remains low.4 Barriers to use include lack of knowledge or

130. AHRQ Evidence-based Practice Center Program Research Gaps Summary: Primary Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
     March 01, 2022 - /products/safety-vaccines/research Purpose The scope of this systematic review of the evidence was … to assess the safety of vaccines in the immunization schedule recommended for children and adolescents … Key Messages • Since the prior 2014 AHRQ report on vaccine safety, we found no new evidence of increased … an opioid safety initiative, provision of patient information and pain management training for clinicians … • Trials that evaluate the long-term efficacy and safety using various doses of antipsychotics and

131. Case Study Comparing Bayesian and Frequentist Approaches for Multiple Treatment Comparisons (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research.pdf
     March 01, 2013 - this drug’s safety. … and safety. … Clinical efficacy and safety of tolterodine in the treatment of overactive bladder: a pooled analysis … Sponsorship hepatic function or renal impairment); subjects with hematuria, or a positive urine culture … Clinical efficacy and safety of tolterodine in the treatment of overactive bladder: a pooled analysis

132. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_executive.pdf
     April 01, 2011 - to require a larger sample size to accrue adequate data on safety and tolerability as well as efficacy … Brief report: application of the TEACCH program on Chinese pre-school children with autism—does culture … Acute and long- term safety and tolerability of risperidone in children with autism. … Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: part A—medical … Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: part B—behavioral

133. #05 DEPRESSION (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - But one expert with a research 5 background, citing ketamine’s safety risk and lack of long-term … In contrast, scopolamine’s known safety profile and possible oral and patch delivery options, bolstered … additional efficacy data, particularly to confirm SPARX’s efficacy for non–New Zealanders, whose culture … A double-blind study to assess the efficacy and safety of intranasal esketamine for the rapid reduction … A study to evaluate the safety and efficacy of intranasal esketamine in treatment-resistant depression

134. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-psoriatric_research-protocol.pdf
     December 06, 2010 - More importantly, it is unclear how the effectiveness and safety of different types of combination therapy … of patients based on stage of disease, history of prior therapy, demographics, concomitant therapies … or sparse data, high probability of publication bias, and magnitude of the effect. … Summary of Protocol Amendments In the event of protocol amendments, the date of each amendment will … of the final draft of the report.

135. Assessing the Risk of Bias of Individual Studies in Systematic Reviews of Health Care Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias-individual-studies_methods.pdf
     March 01, 2012 - beliefs, desire for academic recognition, and so on.30 Third, the multiple pathways by which sponsorship … Empirical evidence across diverse medical fields indicates that reporting of safety information—including … Improving safety reporting from randomised trials. Drug Saf 2002;25(2):77-84. … Completeness of safety reporting in randomized trials: an evaluation of 7 medical areas. … XI Cochrane Colloquium: Evidence, Health Care and Culture; 2003 Oct 26-31; Barcelona, Spain. 19.

136. Disposition of Comments CER 185 Tympanostomy Tubes in Children With Otitis Media (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-disposition.pdf
     May 05, 2017 - two Phase 3 studies1,2,3 are relevant to KQ3 as they contained a TT treatment arm and measured safety … For brevity and ease of comparison, we have presented our assessments of Strength of Evidence this … surveillance of otopathogens in future TT trials, I don’t think that bacterial cultures are helpful … ’t agree with the authors that bacterial cultures will substantially benefit outcome assessment in … We agree that the benefit of culture is unclear.

137. Disposition of Comments CER 185 Tympanostomy Tubes in Children With Otitis Media (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/tympanostomy-tubes-disposition.pdf
     May 05, 2017 - two Phase 3 studies1,2,3 are relevant to KQ3 as they contained a TT treatment arm and measured safety … For brevity and ease of comparison, we have presented our assessments of Strength of Evidence this … surveillance of otopathogens in future TT trials, I don’t think that bacterial cultures are helpful … ’t agree with the authors that bacterial cultures will substantially benefit outcome assessment in … We agree that the benefit of culture is unclear.

138. Disposition of Comments for CER 161 Major Depressive Disorder (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder-disposition-160504.pdf
     December 08, 2015 - , particularly if done in cultures or countries in which significant differences might be expected … illness that may make acupuncture more aligned with belief systems in China vs. in the US. … Cultural belief systems can also influence reporting of psychiatric symptoms, insight into having a … here given the implications for patient safety. … the patient sample, or the location/ culture and setting in which the study was done.

139. Research Protocol: Care Interventions for PeopleWith Dementia (PWD) and Their Caregivers (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pwd-care-interventions-protocol.pdf
     February 22, 2019 - estimated 17 billion hours of care at an economic value of $232.1 billion, and about two-thirds of … inclusion Safety/perceived safety Utilization of healthcare service outcomes: Admission to nursing … Community level outcomes (informal caregivers): Engagement in community activities, Perceived inclusion Safety … /perceived safety Turnover and retention (formal caregivers) Utilization of healthcare service (e.g … primary caregiver 21 • Cognitive reframing (changing caregivers’ maladaptive behaviors or beliefs

140. Executive Summary_Systematic Review: Association of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, and Body Composition (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-executive-summary.pdf
     March 01, 2025 - level of 300 grams of carbohydrates per day. … ; RR = relative risk; SOE = strength of evidence Systematic Review of the Effect of Dietary Digestible … Evaluation of the shapes of these associations demonstrates certain ranges of carbohydrate intake that … Food Safety Authority of Ireland. … Review of the Effect of Dietary Digestible Carbohydrate Intake on Risk of Type 2 Diabetes, Growth, Size