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effectivehealthcare.ahrq.gov/sites/default/files/module_i1.ppt
May 29, 2025 - groups with distinct cultures and perspectives on research and knowledge, with neither group fully understanding … of the evidence about the benefits and risks of alternative courses of action” (Guyatt, 2002).
… with accurate, independent, scientifically rigorous information for comparing the effectiveness and safety … Increased application of evidence
Lower reading level of research reports
Increased relevancy of research … Increased application of evidence
Lower reading level of research reports
Increased relevancy of research
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
July 13, 2011 - The mechanism of action of most of these agents is poorly understood. … KQ4a: For adults with a depressive syndrome, do second-generation antidepressants
differ in safety, … b: Are there any differences in safety, adverse events, or adherence between
immediate release and … symptoms (anxiety, insomnia, melancholia, pain, psychomotor changes, and
somatization), KQ4 focuses on safety … of the final draft of the report.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-centered-medical-home_research-protocol.pdf
February 23, 2012 - of improving patient experiences,
outcomes, safety, and system efficiency.10-12 It is based on 40 years … PCMH
interventions hold promise as a pathway to improved primary health care quality, safety,
efficiency … communication; and a
systems-based approach to quality and safety.11
Multiple organizations have … A systems-based approach to quality, safety, and delivery of evidence-based care. … quality and/or safety data.
6.
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effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1412.pdf
December 01, 2014 - However, researchers now know that other factors including genetics, metabolism,
behavior, environment, culture … However, experts generally indicated a need for more
trials to determine the safety and efficacy of … term
safety and efficacy of the device in the treatment of obesity has not been established.”13 … safety concerns. … A prospective,
randomized multicenter study to evaluate the
safety and efficacy of the ReShape Duo
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
October 29, 2012 - Safety surveillance alerts: None
Conclusion: 5/11 conclusions are possibly out of date
17 … detail and included patient
history, physical and pelvic
examination, urine culture, and other
instrumental … the
literature about the efficacy and safety of
botulinum toxin in the management of
OAB.522
Continence … Efficacy
and
safety
of
low
doses
of
onabotulinumtoxinA
for
the
treatment … detail and included patient history, physical
and pelvic examination, urine culture, and other instrumental
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
December 01, 2011 - Studies must have used toxigenic culture, cell
cytotoxicity assay, or combinations of tests as the
reference … strategies with the belief that these will
improve institutional practices and health care quality
and … difficile
tcdB, and a glutamate dehydrogenase detection assay to
cytotoxin testing and cytotoxigenic culture … Comparison of real-time PCR for detection of the tcdC
gene with four toxin immunoassays and culture in … immune whey and metronidazole for recurrent
Clostridium difficile-associated diarrhoea: efficacy and
safety
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effectivehealthcare.ahrq.gov/sites/default/files/pregnancy_hi_impact.pdf
January 01, 2012 - be developed for different
cultures and literacy levels. … milk from a
source other than her own, only milk from a source that has been screened to ensure the safety … Overall, experts agreed that while more safety and efficacy studies must be performed to determine … Overall, experts opined further studies need to be conducted
to properly evaluate the efficacy and safety … Food and Drug Administration
Center for Food Safety and Applied Nutrition;
2010 Dec 6. 6 p.
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effectivehealthcare.ahrq.gov/sites/default/files/crosscutting_hi_impact.pdf
January 01, 2012 - to
improve safety, outcomes, and quality of care for elderly patients in the ED. … the program include: (1) to build a sustainable safety net system
that links ED patients who lack … culture of ED use, the potential inconvenience of having to keep
appointments and visit the clinic … improve patient safety by providing a more
senior-friendly environment, assessment of needs, and education … First, “a large culture change is anticipated,” in that “patients over 65
would be assessed in a different
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-end-of-life-indicators-symposium_research.pdf
April 01, 2010 - patients, and policymakers seeking unbiased information
about the outcomes, clinical effectiveness, safety … ,
values and beliefs, meaning, purpose, hope, and closure; refining and focusing this definition
would … Evaluating claims-based indicators of the
intensity of end-of-life cancer care. … A systematic review of measures of end-of-
life care and its outcomes. … Improving patient safety by
implementing a standardized and consistent
approach to hand-off communication
-
effectivehealthcare.ahrq.gov/sites/default/files/15_crosscutting_potential_high_impact_2012-12-11.pdf
January 01, 2012 - the senior population to improve safety, outcomes, and quality of care for elderly
patients in the … Patients in Emergency
Departments to Community Care
Emergency departments (EDs) are often used as a safety … the program include: (1) to build a sustainable safety
net system that links patients visiting the … culture of ED use, the potential inconvenience of long wait times,
and transportation issues. … Including safety-net providers in integrated
delivery systems: issues and options for
policymakers
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1512.pdf
December 01, 2015 - However, researchers now know that other factors including genetics, metabolism,
behavior, environment, culture … term safety and efficacy of the device in the
treatment of obesity has not been established.”23 A … Perioperative safety in the longitudinal
assessment of bariatric surgery. … Safety of antiobesity drugs. Ther Adv Drug Saf.
2013;4(4):171-81. … Safety and
tolerability of liraglutide 3.0mg following 56
weeks of randomised treatment in overweight
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/ems-911-workforce-topic-development-brief.pdf
February 01, 2022 - (EMS) workforce, Public Safety Telecommunicators (911 call takers and
dispatchers), are likely subjected … which individuals “perpetrate,
fail to prevent or witness events that contradict deeply held moral beliefs … Highway Traffic
Safety Administration (NHTSA) to inform their decision about whether to commission … Coping among public safety personnel: A
systematic review and meta–analysis. … Reducing the impacts of exposure to
potentially traumatic events on the mental
health of public safety
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
June 01, 2014 - However, researchers now know that other factors including genetics,
metabolism, behavior, environment, culture … However, experts generally indicated a need for more
trials to determine the safety and efficacy of … term safety and efficacy of the device in the treatment of obesity has
not been established.”10 … Some experts
expressed concern about the long-term safety of this intervention, citing the history … Use:
The safety and efficacy of co-administration of BELVIQ with
other products intended for weight
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1306.pdf
July 01, 2013 - However, researchers now know that other factors including genetics,
metabolism, behavior, environment, culture … safety evaluation. … term
safety and efficacy of the device in the treatment of obesity has not been established.”34 … Two experts with
health systems and administration backgrounds highlighted the belief that ReShape … :
The safety and efficacy of co-administration of
BELVIQ with other products intended for weight
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
December 01, 2013 - However, researchers now know that other factors including genetics,
metabolism, behavior, environment, culture … term
safety and efficacy of the device in the treatment of obesity has not been established.”10 … safety and efficacy concerns. … Two experts with
health systems and administration backgrounds highlighted the belief that ReShape … :
The safety and efficacy of co-administration of
BELVIQ with other products intended for weight
-
effectivehealthcare.ahrq.gov/sites/default/files/15_crosscutting_potential_high_impact_june_2012.pdf
January 01, 2012 - the senior population to improve safety, outcomes, and quality of care for elderly
patients in the … Departments to Community Care
Emergency departments (EDs) are often used as a safety net for patients … the program include: (1) to build a sustainable safety
net system that links patients visiting the … culture of ED use, the potential inconvenience of long wait times,
and transportation issues. … senior-specific care is “common sense” and is likely to “have
a big health impact by improving patient safety
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-evidence-summary.pdf
August 01, 2018 - Efficacy and safety of
olanzapine in the treatment of Japanese patients with bipolar
I disorder in … A randomized, double-
blind, placebo-controlled efficacy and safety study of quetiapine
or lithium as … A comparison of the
efficacy, safety, and tolerability of divalproex sodium and
olanzapine in the treatment … Evaluation of the efficacy
and safety of paliperidone extended-release in the treatment of
acute mania … Efficacy and safety of long-term
fluoxetine versus lithium monotherapy of bipolar II disorder:
a randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
February 01, 2018 - However, they also expressed the belief that data and analyses regarding such harms could
generally … The
quality of safety reporting in trials is still
suboptimal: survey of major general medical
journals … Cardiovascular safety of non-steroidal anti-
inflammatory drugs: network meta-analysis. … http://www.fda.gov/Safety/MedWatch/HowToReport/ucm053087.htm
http://www.fda.gov/Safety/MedWatch/HowToReport … • Focus on two or three of the most important safety outcomes.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
January 01, 2023 - The Effect of Dietary Digestible Carbohydrate Intake on Risk of Cardiovascular Disease
Evidence-based … Assessment of the Risk of Bias of Individual Studies
We will evaluate the risk of bias of the included … the studies (i.e., risk of bias), precision (based on the size of the body of
evidence, number of events … Food Safety Authority of Ireland. … Assessment of the Risk of Bias of Individual Studies
E. Data Synthesis
F.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/labor-nitrous-oxide_executive.pdf
August 01, 2012 - one of fair quality,32
and seven of poor quality.16-17, 20-21, 24, 27, 30 Measures
of satisfaction … Effect of Nitrous Oxide on the Route of Birth
Six studies compared the route of birth in women who … The strength of evidence for the effect
of nitrous oxide on route of birth was insufficient. … Safety and risks of nitrous oxide labor analgesia: A
review. … Safety and analgesic efficacy assessed by a double-blind,
placebo-controlled study.