-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/colorectal-cancer-screening_research-protocol.pdf
May 18, 2011 - Outcomes KQ 1: Final Health Outcomes
1) CRC-specific or all-cause mortality
2) CRC incidence … FIT = fecal immunohistochemical
testing; FOBT = fecal occult-blood testing; PICOTS = population, intervention … with CRC. … Persons at high risk for CRC
include persons with a strong family history of CRC including syndrome … reviewers to determine if an article may
meet the inclusion criteria for study design, population, and intervention
-
effectivehealthcare-admin.ahrq.gov/products/colorectal-cancer-screening/research-protocol
December 01, 2019 - enema; FIT = fecal immunohistochemical testing; FOBT = fecal occult-blood testing; PICOTS = population, intervention … Outcomes
KQ 1: Final Health Outcomes
CRC-specific or all-cause mortality
CRC incidence … with CRC. … Outcomes
KQ 1: CRC incidence (or advanced neoplasia incidence if CRC incidence is not reported), … reviewers to determine if an article may meet the inclusion criteria for study design, population, and intervention
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/disparities-quality-improvement_executive.pdf
August 01, 2012 - CRC = colorectal cancer; QI = quality improvement; RCT = randomized controlled trial. … • No disparity in CRC screening rate was observed at baseline.
• The intervention was associated with … increases in CRC screening
in both groups, with neither group having a greater effect of the
intervention … was effective at
increasing CRC screening for both groups. … had a similar incidence of CRC
screening during 1 year of followup in the intervention group as
compared
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/colorectal-cancer-liver-metastases-therapies_research-protocol.pdf
September 27, 2012 - spread and who are receiving liver-
directed therapy as an adjunct to systemic chemotherapyInvolve an intervention … Data Elements
The following data elements will be abstracted from the intervention … Analysis: adjustment for potential confounders and intention-to-treat analysis
• The rating of intervention … • The quality of included nonrandomized comparative intervention studies will also be
assessed … Evaluating non-randomised intervention studies.
Health Technol Assess 2003;7(27):iii-x, 1-173.
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effectivehealthcare-admin.ahrq.gov/products/colorectal-cancer-liver-metastases-therapies/research-protocol
December 01, 2019 - extrahepatic spread and whose metastatic disease is refractory to systemic chemotherapy
Involve an intervention … Analysis: adjustment for potential confounders and intention-to-treat analysis
The rating of intervention … The quality of included nonrandomized comparative intervention studies will also be assessed based on … The quality of included single-arm intervention studies will be assessed based on a set of study characteristics … Evaluating non-randomised intervention studies. Health Technol Assess 2003;7(27):iii-x, 1-173.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-233-diverticulitis-evidence-summary.pdf
October 01, 2020 - various treatment options, preventive options for long-
term recurrence, and detection strategies for CRC … with recent diverticulitis, those who undergo
colonoscopy may, ultimately, have similar rates of CRC … diagnoses as those who
did not; however, no studies evaluated comparative risks of CRC death. … ; however, no studies evaluated comparative risks of CRC
death. … Among these patients, about 2 percent have CRC, 7 percent have advanced colonic
neoplasia (CRC or advanced
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_executive.pdf
December 01, 2012 - This is followed by a discussion
of the treatment of CRC liver metastasis. … Our assessment of risk of bias in the included case-
series intervention studies was based on a set of … Evidence is also
presented in text organized by outcome and intervention. … Systemic chemotherapy alone was not a
relevant intervention or comparator for this review. … Additional heterogeneity exists for the context in which
the intervention was delivered.
-
effectivehealthcare-admin.ahrq.gov/products/diverticulitis/research
January 01, 2022 - diagnoses as those who did not; however, no studies evaluated comparative risks of CRC death. … who had complicated diverticulitis (with abscess, peritonitis, etc.) are at increased risk of having CRC … There is low SoE that patients with recent acute diverticulitis may be at increased risk of CRC compared … those who undergo colonoscopy soon after acute diverticulitis may ultimately have similar rates of CRC … Patients 50 years and older may be at increased risk of CRC (moderate SoE) or premalignant lesions (low
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_executive.pdf
February 01, 2012 - the third leading cause
of cancer deaths in the United States.1
Incidence and mortality rates for CRC … in reducing morbidity
(CRC incidence) or mortality (all-cause or CRC-specific)? … To detect CRC?
b. To detect precancerous lesion(s)?
2.2. … To detect CRC?
b. To detect precancerous lesion(s)?
Key Question 3. Interval of Screening. … decision
makers can use robust models that have been developed
by the National Cancer Institute Cancer Intervention
-
effectivehealthcare-admin.ahrq.gov/products/colorectal-cancer-liver-metastases-therapies/research
December 01, 2019 - of various local hepatic therapies for metastases to the liver from unresectable colorectal cancer (CRC … insufficient to permit conclusions on the comparative effectiveness of these therapies for unresectable CRC
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/diverticulitis-comments.pdf
October 12, 2020 - o The reviewer also suggested evaluating colorectal cancer (CRC) rates found
on colonoscopy by country … : The key points
(5th bullet point) highlights a finding that
older people are at higher risk for CRC … the reason for the age 50
cutpoint (used by 5 studies) is to match
general population guidance for CRC … SoE that patients with recent diverticulitis
may have an increased likelihood of
having undiagnosed CRC … or advanced
colonic neoplasia (CRC or advanced
adenomas).”
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/health-equity-protocol.pdf
January 01, 2020 - harms of screening
Aspirin use to prevent
cardiovascular disease
(CVD) and colorectal
cancer (CRC … 10% 10-year CVD
risk
Use of low-dose aspirin
for prevention purposes
CVD events (MI, CVD);
CRC … mortality; and
quality of life, harms of
interventions
Abbreviations: CHD=coronary heart disease; CRC … 2003 B October 2015
Aspirin use to prevent cardiovascular
disease (CVD) and colorectal cancer
(CRC … ): preventive medication
CVD: 2007
CRC: 2009
B April 2016
Breast cancer screening 2002 B: Ages
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effectivehealthcare-admin.ahrq.gov/products/health-equity-preventive/protocol
August 31, 2018 - 10-year CVD risk
Use of low-dose aspirin for prevention purposes
CVD events (MI, CVD); CRC … ; and quality of life, harms of interventions
Abbreviations: CHD=coronary heart disease; CRC … October 2015
Aspirin use to prevent cardiovascular disease (CVD) and colorectal cancer (CRC … ): preventive medication
CVD: 2007
CRC: 2009
B
April 2016
Breast cancer … A
Current: 2015
Draft: In process
Abbreviations: CVD=cardiovascular disease, CRC
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
December 01, 2012 - What is the Current Evidence for the Technology/Intervention? … What is the current evidence for the
technology/intervention? … What is the cCurrent evidence for the
technology/intervention? … ; the peer-reviewed publication24 for the fifth commercially available assay
12
(OncoDefender-CRC … ]; a secondary objective is to predict response to
therapy for various stages of CRC.)
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/infectiousdisease_hi_impact.pdf
December 01, 2013 - available for this
patient population.
58
Screening and early treatment for colorectal cancer (CRC … Patients
treated surgically for localized CRC have a long-term survival of 91%, compared with patients … common symptoms are
confirmed with either barium enema radiography or colonoscopy.
64
Localized CRC … Patients attending HIV clinics for routine treatment and monitoring can be screened for CRC
with anal … Pap smears to reduce the incidence of advanced CRC.
12
AHRQ Healthcare
Horizon Scanning
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-222-evidence-summary-health-equity.pdf
January 01, 2020 - Tobacco
smoking
cessation
0 3 1 2 0
Cardio-
vascular
disease
Aspirin to
prevent CVD
and CRC … type
2 diabetes
screening
0 0 0 0 0
Obesity
screening and
management
0 0 1d 2 7
Abbreviations: CRC … A tobacco smoking cessation intervention for
women smokers attending their child’s pediatric
visit … A
weight loss intervention provided by primary care
physicians for low-income, overweight and obese … Preventive Service Intervention
Number
of Studies;
Study Design;
Participants (n) Overall Effect
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
March 29, 2011 - What is the comparative effectiveness of large neutral amino acids (LNAAs) with
dietary intervention … What is the comparative effectiveness of LNAAs with dietary intervention versus
dietary intervention … Chapman &
Hall/CRC Texts in Statistical Science: Boca Raton, FL.
28. … What is the comparative effectiveness of LNAAs with dietary intervention versus dietary intervention … Chapman & Hall/CRC Texts in Statistical Science: Boca Raton, FL.
28.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cell-free-dna-appendix-c.xlsx
September 01, 2024 - Presentation Cervical Cancer Diagnosis from Usual Care Screening Cervical Cancer Diagnosis from MCST CRC … Unknown Diagnosis Method CRC Diagnosis from Clinical Presentation CRC Diagnosis from Usual Care Screening … CRC Diagnosis from MCST Esophageal Cancer Unknown Diagnosis Method Esophageal Cancer Diagnosis from … Cancer signal of origin reporting possible for six cancer types (CRC, esophageal, liver, lung, ovarian … Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_disposition-comments.pdf
December 11, 2012 - CRC is the 3rd most
commonly diagnosed cancer. … We have edited this sentence to reflect that CRC is
third most commonly diagnosed cancer and
included … Systemic
chemotherapy alone was not a relevant
intervention or comparator for this review.
-
effectivehealthcare-admin.ahrq.gov/products/nursing-home-safety/research-protocol
December 01, 2019 - Challenges exist in the intervention literature on several planes. … Guiding Question 1: Describe the Intervention for Patient Safety Practices in Nursing Home Settings … ulcers in long-term care: a paired randomized intervention study. … A multifactorial intervention for the prevention of falls in psychogeriatric nursing home patients, a … Handbook of Human Factors in Medical Device Design: CRC Press/Taylor & Francis Group; 2010.