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1. COPD | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/health-topics/copd
   October 11, 2019 - Description COPD (chronic obstructive pulmonary disease) makes it hard for you to breathe. … At first, COPD may cause no symptoms or only mild symptoms. … Research Report December 4, 2009 Mortality Risk in Chronic Obstructive Pulmonary Disease Patients … Research Report Archived December 4, 2009 Outcomes Associated With Tiotropium use in Chronic … Obstructive Pulmonary Disease Patients Back to Top

2. Pharmacologic and Non-pharmacologic Therapies in Adult Patients with Acute Exacerbation of COPD: A Systematic Review | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/products/copd/protocol
   January 01, 2019 - Background and Objectives for the Systematic Review Chronic Obstructive Pulmonary Disease (COPD) is … Initiative for Chronic Obstructive Lung Disease (GOLD) as "an acute event characterized by a worsening … Outcomes following acute exacerbation of severe chronic obstructive lung disease. … Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary disease. … Definition of Terms COPD:  Chronic obstructive pulmonary disease: a preventable and treatable disease

3. Outcomes Associated With Tiotropium use in Chronic Obstructive Pulmonary Disease Patients | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/products/copd-anticholinergic-medicines/research
   January 01, 2020 - NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. … A 4-year trial of tiotropium in chronic obstructive pulmonary disease. … A 4-year trial of tiotropium in chronic obstructive pulmonary disease. … Tiotropium for stable chronic obstructive pulmonary disease: A meta-analysis. … A 4-year trial of tiotropium in chronic obstructive pulmonary disease.

4. Mortality Risk in Chronic Obstructive Pulmonary Disease Patients Using Theophylline | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/products/copd-management/research
   November 01, 2017 - SHARE: Mortality Risk in Chronic Obstructive Pulmonary Disease … Participants Patients with a diagnosis of chronic obstructive pulmonary disease that were 45 years … obstructive pulmonary disease exacerbations and chronic obstructive pulmonary disease-related hospitalizations … obstructive pulmonary disease exacerbations and chronic obstructive pulmonary disease hospitalizations … Obstructive Pulmonary Disease Patients Using Theophylline.

5. Pharmacologic and Non-pharmacologic Therapies in Adult Patients with Acute Exacerbation of COPD: A Systematic Review (pdf file)
   effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/copd-research-protocol.pdf
   April 11, 2018 - Background and Objectives for the Systematic Review Chronic Obstructive Pulmonary Disease (COPD) is … Outcomes following acute exacerbation of severe chronic obstructive lung disease. … obstructive lung disease*" or "chronic obstructive lung disorder*" or "chronic obstructive pulmonary … obstructive lung disease*" or "chronic obstructive lung disorder*" or "chronic obstructive pulmonary … obstructive lung disease" OR "chronic obstructive lung disorder" OR "chronic obstructive pulmonary

6. Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/products/copd/research
   January 01, 2021 - obstructive pulmonary disease. … obstructive pulmonary disease (ECOPD). … Although chronic obstructive pulmonary disease is a common condition, the evidence base for most interventions … Pharmacologic therapies in patients with exacerbation of chronic obstructive pulmonary disease: a systematic … Nonpharmacologic therapies in patients with exacerbation of chronic obstructive pulmonary disease: a

7. Evidence Summary: Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD (pdf file)
   effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-221-copd-evidence-summary_0.pdf
   October 01, 2019 - obstructive pulmonary disease. … The Global Initiative for chronic obstructive lung disease (GOLD) defines ECOPD in its 2019 report … to increase applicability of the results to patients with chronic airflow obstruction. … Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease. … Outcomes following acute exacerbation of severe chronic obstructive lung disease.

8. Outcomes in COPD patients treated with theophylline (pdf file)
   effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/copd-management_research.pdf
   December 01, 2009 - pulmonary disease exacerbations and chronic obstructive pulmonary disease-related hospitalizations. … obstructive pulmonary disease exacerbations and chronic obstructive pulmonary disease hospitalizations … NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. … Value of theophylline treatment in patients handicapped by chronic obstructive lung disease. … The use of theophylline in chronic obstructive pulmonary disease.

9. Outcomes in COPD patients treated with theophylline (pdf file)
   effectivehealthcare-admin.ahrq.gov/sites/default/files/decide16final-mortality-risk-in-copd-pts-using-theophylline.pdf
   December 01, 2009 - pulmonary disease exacerbations and chronic obstructive pulmonary disease-related hospitalizations. … obstructive pulmonary disease exacerbations and chronic obstructive pulmonary disease hospitalizations … NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. … Value of theophylline treatment in patients handicapped by chronic obstructive lung disease. … The use of theophylline in chronic obstructive pulmonary disease.

10. Pharmacologic and Non-pharmacologic Therapies in Adult Patients with Acute Exacerbation of COPD: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/copd
    January 26, 2018 - Pharmacologic and Non-pharmacologic Therapies in Adult Patients with Acute Exacerbation of COPD

11. RESPONSE TO REQUEST FOR WORK ASSIGNMENT (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/copd-anticholinergic-medicines_research.pdf
    December 01, 2009 - NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. … A 4- year trial of tiotropium in chronic obstructive pulmonary disease. … A 4- year trial of tiotropium in chronic obstructive pulmonary disease. … Tiotropium for stable chronic obstructive pulmonary disease: A meta- analysis. … A 4- year trial of tiotropium in chronic obstructive pulmonary disease.

12. PULMONARY with "Discussions" in Exec Summary (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - ES 3 Off-Label Azithromycin for Prevention of Chronic Obstructive Pulmonary Disease Exacerbations … Obstructive Pulmonary Disease Exacerbations Unmet need: Chronic obstructive pulmonary disease (COPD … Chronic obstructive pulmonary disease (COPD) fact sheet. [internet]. … Chronic obstructive pulmonary disease. In: Medscape Reference [formerly eMedicine] [internet]. … Chronic obstructive pulmonary disease (COPD) fact sheet. [internet].

13. CER 221 Disposition of Comments: Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-221-copd-comments_0.pdf
    October 11, 2019 - ” to “exacerbations of COPD” or “COPD exacerbations” throughout the report. … Risk trajectories of readmission and death in the first year after hospitalization for chronic obstructive … pulmonary disease. … High frequency chest wall oscillation for asthma and chronic obstructive pulmonary disease exacerbations … Effect of systemic glucocorticoids on exacerbations of chronic obstructive pulmonary disease.

14. PowerPoint Presentation (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/krishnan_ahrq-mcda-presentation.pdf
    August 27, 2012 - Chronic obstructive pulmonary disease (COPD) as a key health condition. 2. … Analytic hierarchy process to establish priorities. 2 Chronic Obstructive Pulmonary Disease … of hospital readmissions – $49.9 billion / yr NHLBI Chartbook 3 Chronic Obstructive Pulmonary … Disease (COPD) • Key health condition in US • Model complex medical condition – Multiple co-morbid … care • Care coordination in COPD Year 2 (AHP) May 20-21, 2010 New Orleans • Acute COPD

15. PULMONARY with "Discussions" in Exec Summary (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - *Off-label azithromycin for prevention of chronic obstructive pulmonary disease exacerbations Lower … obstructive pulmonary disease (COPD) exacerbations. … Obstructive Pulmonary Disease Exacerbations Unmet need: Chronic obstructive pulmonary disease (COPD … Chronic obstructive pulmonary disease. … HS1317 - Off-label azithromycin for prevention of chronic obstructive pulmonary disease exacerbations

16. Use of Analytic Hierarchy Process to elicit stakeholder preferences for prioritizing research (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/mcda-krishnan.pdf
    August 27, 2012 - Chronic obstructive pulmonary disease (COPD) as a key health condition. 2. … Slide 3 Chronic Obstructive Pulmonary Disease (COPD) • Key health condition in US – Most common … Picture: NHLBI Chartbook called Public Health Strategic Framework for CPOD Prevention Slide 4 Chronic … Obstructive Pulmonary Disease (COPD) • Key health condition in US • Model complex medical condition … care • Care coordination in COPD Year 2 (AHP) • May 20-21, 2010 • New Orleans • Acute COPD care

17. COPD is common and respiratory failure due to COPD is an increasingly common disorder. Use of non-invasive positive pressure ventilation (NPPV) for patients with respiratory failure due to exacerbatons of COPD. Several trials and… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/copd-is-common-and-respiratory-failure-due-to-copd-is-an-increasingly-common-disorder-use-of-non-invasive-positive-pressure-ventilation-nppv-for-patients-with-respiratory-failure-due-to-exacerbatons-of-copd-several-trials-an
    November 01, 2017 - is common and respiratory failure due to COPD is an increasingly common disorder. … is common and respiratory failure due to COPD is an increasingly common disorder. … is common and respiratory failure due to COPD is an increasingly common disorder. … is common and respiratory failure due to COPD is an increasingly common disorder. … https://effectivehealthcare.ahrq.gov/get-involved/nominated-topics/copd-is-common-and-respiratory-failure-due-to-copd-is-an-increasingly-common-disorder-use-of-non-invasive-positive-pressure-ventilation-nppv-for-patients-with-respiratory-failure-due-to-exacerbatons-of-copd-several-trials-an

18. PULMONARY with "Discussions" in Exec Summary (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - Obstructive Pulmonary Disease Exacerbations Unmet need: Chronic obstructive pulmonary disease (COPD … Chronic obstructive pulmonary disease. In: Medscape Reference [formerly eMedicine] [internet]. … HS1317 - Off-label azithromycin for prevention of chronic obstructive pulmonary disease exacerbations … HS1317 - Off-label azithromycin for prevention of chronic obstructive pulmonary disease exacerbations … HS1317 - Off-label azithromycin for prevention of chronic obstructive pulmonary disease exacerbations

19. Systematic Review of Intermittent Inhaled Corticosteroids and of Long-acting Muscarinic Antagonists for Asthma | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/asthma-pharmacologic-treatment/research-protocol
    April 01, 2021 - obstructive pulmonary disease (COPD) Bevespi Aerosphere (glycopyrrolate/formoterol fumarate) … Long-term, maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary … obstructive pulmonary disease (COPD)‡ Stiolto Respimat (tiotropium bromide/olodaterol) Long-term … , once-daily maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary … of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD) Search

20. Multi-Criteria Decision Analysis Techniques to Integrate Stakeholder Preferences in Comparative Effectiveness Research (Audio Presentation) | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/stakeholders-engagement-others/slides-2012
    November 01, 2017 - Krishnan is an expert in clinical investigation in asthma and chronic obstructive pulmonary disease ( … COPD) and is a leader in the field of comparative effectiveness research. … He is the Chair of the Steering Committee for the COPD Outcomes-based Network for Clinical Effectiveness … a national research infrastructure to conduct comparative effectiveness / implementation studies in COPD … multicenter national network for efficacy studies in asthma, site Principal Investigator for the NHLBI COPD