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effectivehealthcare-admin.ahrq.gov/products/renal-update/research
January 01, 2020 - Data sources
MEDLINE®, Embase®, the Cochrane Central Register of Controlled Trials, Cochrane Database … We included 9 randomized controlled trials (RCTs), 11 nonrandomized comparative studies, 67 cohorts (
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effectivehealthcare-admin.ahrq.gov/products/pelvic-pain/research
March 01, 2020 - Results
Of 36 included studies, 18 were randomized controlled trials (RCTs) (2 good, 3 fair, and 13 … approaches typically addressed hormonal management of endometriosis-related CPP and were not placebo controlled
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effectivehealthcare-admin.ahrq.gov/products/COVID-19-pharmaceutical-treatments/research
September 01, 2023 - non-serious adverse events, effectiveness outcomes, Timing No restriction NA Study Design Randomized controlled … trials, controlled clinical trials, observational studies with a comparison group, case-control studies … following data will be abstracted Study identifier (author) and publication year Study design Randomized Controlled … Trial (RCT) Controlled Clinical Trial Retrospective cohort Prospective cohort Case control Other, specify
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effectivehealthcare-admin.ahrq.gov/products/dietary-supplements/research-protocol
December 01, 2019 - Comparison intervention characteristics: In placebo-controlled trials, description/definition of control … trials (RCT and non-RCT)
Observational controlled studies
Uncontrolled experimental (for KQ 5 only … There is evidence that randomized controlled trials published in some Chinese journals lacked an adequate … Many non-randomized controlled trials were published as randomized controlled trials. 3
Except for … Language bias in randomised controlled trials published in English and German.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy_research-protocol.pdf
September 14, 2016 - o Ideally studies will include patients with allergic asthma whose symptoms are not
controlled adequately … We will search PubMed, Embase, and Cochrane Central Register of Controlled Trials
(CENTRAL). … We will consider the strength of the study designs; randomized controlled trials will be graded as
having … Factors that may limit
applicability include age, asthma severity or poorly controlled asthma, type … asthma may be
excluded in some controlled trials of immunotherapy.
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effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-surveillance/research-protocol
December 01, 2019 - Randomized controlled trials, nonrandomized comparative studies, and cohort studies; for adverse events … A comprehensive search of the scientific literature in Medline, the Cochrane Central Register of Controlled … These systematic reviews, collectively, analyzed a small number of randomized controlled trials and more … Effectiveness and Comparative Effectiveness Reviews (hereafter, Methods Guide ). 4 For randomized controlled … of ultimate health outcomes or that the comparison of interest was not made in individual randomized controlled
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2023-update-executive-summ.pdf
January 01, 2023 - Executive Summary
Main Points
• This update adds 60 newly published randomized controlled … for Posttraumatic Stress
Disorder: Groundwork for a Publicly
Available Repository of Randomized
Controlled … Development of the PTSD-Repository: a
publicly available repository of randomized
controlled trials
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-255-transitions-care-pediatric-to-adult-services-evidence-summary.pdf
May 01, 2022 - , Ovid Embase, the Cochrane Central trials (CENTRAL)
registry, and CINAHL to identify randomized controlled … Closing
the gap: Results of the multicenter Canadian
randomized controlled trial of structured transition … diabetes after transition of care from
paediatric to adult services (TrACeD): a
randomised, open-label, controlled
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ischemic-stroke-treatment_executive.pdf
January 01, 2011 - Systematic literature searches were conducted of
MEDLINE, the Cochrane Central Register of
Controlled … While perhaps
the best “controlled” data available to date, this analysis
is fraught with limitations … Seven of these studies have
randomized, controlled designs with projected
enrollment ranging from 20 … Six of the
seven randomized controlled trials are allowing the use
of multiple neurothrombectomy devices … It would seem reasonable to conduct
studies to answer such research gaps using a
randomized controlled
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
January 27, 2012 - For KQ 5 (subgroups), double-
blind RCTs, recent systematic reviews, nonrandomized
controlled trials … Evidence from well-controlled trials does
not adequately support the efficacy of disulfiram compared … Results of a double-blind,
placebo-controlled pharmacotherapy trial in alcoholism conducted
in Germany … Oral topiramate for
treatment of alcohol dependence: a randomised controlled trial. … Topiramate for treating
alcohol dependence: a randomized controlled trial.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
April 18, 2013 - Comparative effectiveness randomized
controlled clinical trials answer the questions
which drugs are … We reviewed RCTs and controlled clinical trials
for drugs efficacy and comparative
effectiveness. … We could not find RCTs or controlled clinical
trials of botox efficacy in children. … Differences in subject
characteristics in randomized
controlled clinical trials that
examined drugs … Randomized controlled
clinical trials that examined
adverse effects of preventive
drugs in children
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/mat-retention-strategies-rapid-review-1.pdf
August 01, 2020 - There are several areas for
which future research is needed, given the paucity of controlled studies … A
cluster randomised controlled trial. … Internet-delivered treatment for
substance abuse: a multisite randomized
controlled trial. … KQ3: Not reported
Fair
MAT= medications for addiction treatment; RCT= randomized controlled trial … A cluster
randomised controlled trial.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible.pdf
January 01, 2021 - Settings • All except hospital and acute care • Hospital and acute care
Study design • Randomized controlled … trials
• Nonrandomized controlled trials,
including quasi-experimental and
controlled before-and-after … PICOTS =
populations, interventions, comparators, outcomes, timing, and settings; RCT = randomized controlled … Print, In-Process & Other Non-Indexed Citations, MEDLINE Daily, MEDLINE, Cochrane
Central Registrar of Controlled … For
nonrandomized studies, including quasi-experimental studies, controlled before-and-after
studies
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effectivehealthcare-admin.ahrq.gov/products/antidepressants-update/research-protocol
December 01, 2019 - requirements about the types of trials that need to be conducted (Phase I-III trials with 2 pivotal placebo-controlled … Eligible study designs include randomized controlled trials, non-randomized controlled trials, observational … When sufficient evidence is not available for direct head-to-head comparisons: double-blind, placebo-controlled … design
Head-to-head, double-blind, RCTs
Good or fair quality meta-analyses
Good or fair quality, controlled … design
Head-to-head, double-blind, RCTs
Good or fair quality meta-analyses
Good or fair quality, controlled
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-273-anal-cancer-executive-summary.pdf
August 01, 2024 - Our searches covered publications in MEDLINE®,
Embase®, Cochrane Register of Controlled Trials, and … We included randomized controlled trials (RCTs)
and nonrandomized studies of interventions (NRSIs) comparing … ; RT- radiation
therapy; derm-dermatologic; GI-gastrointestinal; GU-genitourinary; RCT- randomized controlled
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effectivehealthcare-admin.ahrq.gov/products/copd/protocol
January 01, 2019 - This review will focus on evidence from randomized controlled trials as the gold standard design for … PICOTS = populations, interventions, comparators, outcomes, timing, and settings; RCT = randomized controlled … and survival in acute care settings: a comprehensive systematic review and metaanalysis of randomized controlled … Targeted medical nutrition for cachexia in chronic obstructive pulmonary disease: a randomized, controlled … Controlled clinical trials. 1986 Sep;7(3):177-88. PMID: 3802833.
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effectivehealthcare-admin.ahrq.gov/products/methods-guidance-principles/methods
December 01, 2019 - Note that in the absence of controlled studies demonstrating that using enteral supplements improves … Placebo-controlled trials demonstrating an important or unique benefit or harm of a particular drug. … Language bias in randomised controlled trials published in English and German. … The evolution of the randomized controlled trial and its role in evidence-based decision making. … Should meta-analyses of interventions include observational studies in addition to randomized controlled
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effectivehealthcare-admin.ahrq.gov/products/hospital-length-of-stay/protocol
August 01, 2020 - We will search the following databases using controlled vocabulary and text words: MEDLINE, PubMed (unprocessed … We will supplement our searches with the results of exploratory searches for randomized controlled trials … (ERAS) versus standard recovery for elective gastric cancer surgery: a meta-analysis of randomized controlled … /1 track)):ti,ab
3
Combine sets: LOS
#1 OR #2
4
Vulnerable populations – social – controlled … vulnerable populations - social
#4 OR #5
7
Vulnerable populations – diseases/conditions –controlled
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
December 23, 2014 - Prevention: RCTs, nonrandomized controlled trials, prospective cohort studies,
retrospective cohort, … Standard Treatment: RCTs, nonrandomized controlled trials, and prospective
Figure 2. … Nonantibiotic standard treatment: RCTs, nonrandomized controlled trials,
prospective cohort studies, … We will search ClinicalTrials.gov and the International Controlled
Trials Registry Platform (ICTRP) … Placebo--
efficacy and adverse effects in controlled
clinical trials.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
January 01, 2007 - Based on direct
data from randomized controlled trials, most oral
diabetes medications (thiazolidinediones … Only two randomized
controlled trials reported information on peripheral
vascular disease, making it … at reducing short-term nephropathy compared
with metformin, based on two short-duration
randomized controlled … For Key Question 2 (distal diabetes-related
complications)
More randomized controlled trials and prospective … NA There was a suggestion from a few placebo-controlled and head-to-
head trials that meglitinides have