-
effectivehealthcare-admin.ahrq.gov/products/menopause/research
December 01, 2019 - The following electronic databases were searched through January 2014: MEDLINE®, Embase®, Cochrane Controlled … Randomized controlled trials provided the evidence base for symptom relief.
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effectivehealthcare-admin.ahrq.gov/products/diabetes-update-2015/research
December 01, 2019 - Data sources
We searched MEDLINE ® , Embase ® , and the Cochrane Central Register of Controlled Trials … to 70 percent higher for sulfonylureas than metformin (risk difference, 0.1% to 2.9% in randomized controlled
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_appendixes.pdf
January 01, 2009 - Cross-Sectional Studies/
13. 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or 9 or 10 or 11 or 12
14. randomized controlled … trial.pt.
15. controlled clinical trial.pt.
16. randomized.ab.
17. placebo.ab.
18. drug therapy.fs … Cross-Sectional Studies/
13. 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or 9 or 10 or 11 or 12
14. randomized controlled … trial.pt.
15. controlled clinical trial.pt.
16. randomized.ab.
17. placebo.ab.
18. drug therapy.fs … hormone replacement therapy in growth
hormone-deficient adults. an 18-month randomised, placebo-
controlled
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
March 01, 2018 - A randomized controlled trial of
duloxetine in diabetic peripheral neuropathic
pain. … Controlled-release oxycodone for pain in
diabetic neuropathy: a randomized
controlled trial. … Controlled-release oxycodone relieves
neuropathic pain: a randomized controlled
trial in painful diabetic … A multicenter,
double-blind, vehicle-controlled study. The
Capsaicin Study Group. … Controlled study with long-term
follow-up. Diabetes Care. 1992 Jan;15(1):8-
14.
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effectivehealthcare-admin.ahrq.gov/products/fecal-incontinence/research
December 01, 2019 - sources
Ovid MEDLINE ® , Embase ® , PEDro ® , CINAHL ® , AMED, and the Cochrane Central Register of Controlled … Most randomized controlled trials (RCTs) were nonsurgical (n = 38); 13 examined pelvic floor muscle training
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effectivehealthcare-admin.ahrq.gov/products/dyspnea-advanced-cancer/protocol
June 01, 2020 - s):
Patients (age ≥ 18 years of age) with advanced cancer (unlikely to be cured or unlikely to be controlled … concurrent comparison group, with at least 10 patients in each group
For KQ 4: RCTs, nonrandomized controlled … For KQ 4: RCTs, nonrandomized controlled trials, observational studies with a concurrent comparison group … KQ 1–KQ 3:
Exclude trials that are not controlled
Single arm studies [pre-post]
KQ 4: … primary studies: PubMed, Embase ® , CINAHL, ISI Web of Science, and the Cochrane Central Register of Controlled
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-fracture-prevention-evidence-summary.pdf
April 01, 2019 - In short-term (18 to 36 months) randomized
controlled trials (RCTs) for osteoporosis
treatment, bisphosphonates … Of 48 publications
with low or medium risk of bias (ROB), there
were 35 randomized or controlled clinical … trials (9
unique studies) and 13 controlled observational
studies (11 unique studies) (Appendix C … reported BMD status.
3
Long-Term Osteoporosis Drug Treatment
Efficacy
Seven eligible placebo-controlled … Data from controlled, long-term observational
studies suggest that alendronate and
bisphosphonates
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effectivehealthcare-admin.ahrq.gov/products/cultural-competence/research-protocol
December 01, 2019 - Study Design and Quality
Systematic reviews, RCTs, nonrandomized controlled trials, and prospective … trials as topic/
34
randomized controlled trial/
35
random allocation/
36
double … clinical trial.pt.
44
randomized controlled trial.pt.
45
multicenter study.pt. … clinical trial.pt.
44
randomized controlled trial.pt.
45
multicenter study.pt. … clinical trial.pt.
44
randomized controlled trial.pt.
45
multicenter study.pt.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/obesity-research-methods_research-protocol.pdf
February 08, 2017 - Outside of a randomized
controlled trial it is rare for variation in exposure to an intervention to
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amended.pdf
February 07, 2025 - /Exclusion of Studies in the Review: We will include randomized
trials (RCTs) and comparative well-controlled … To be considered well-controlled, comparative NRSIs will have to account for confounding
by age, stage … A cohort study of summary reports of
controlled trials. JAMA. Mar 9 1990;263(10):1401-5. … trial'/exp OR 'phase 3':ti,ab OR
'phase iii':ti,ab OR random*:ti,ab OR RCT:ti,ab)
13 'controlled … ' OR 'non
controlled' OR uncontrolled OR noncontrolled OR 'phase 2' OR 'phase two' OR 'phase ii') NEXT
-
effectivehealthcare-admin.ahrq.gov/products/atypical-antipsychotics-off-label-update/research-protocol
March 01, 2020 - conclusions of the original report might be out of date:
New studies, especially new randomized controlled … antipsychotic against another and provide direct evidence of comparative effectiveness;
“Active” controlled … Timing: The duration of the majority of the controlled trials in this area last from 6 to 26 weeks. … Adverse events will be analyzed for all controlled trials as well as observational studies with at least … For the efficacy and comparative effectiveness analyses, we will focus on controlled trials that report
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ptsd-repository-expanded-protocol.pdf
October 24, 2019 - of Mental Disorders, third edition (DSM-III) in 1980,
there have been over 300 published randomized controlled … length of followup
• Settings:
o No limitation on study setting
• Study Design:
o Randomized controlled … Propranolol/
35. propranolol.ti,ab.
36. exp Randomized Controlled Trials as Topic/
37. exp Randomized … Controlled Trial/
38. double-blind method/ or random allocation/ or single-blind method/
39. … Trials as Topic/
20. exp Randomized Controlled Trial/
21. double-blind method/ or random allocation
-
effectivehealthcare-admin.ahrq.gov/products/measuring-blood-pressure/research-protocol
March 01, 2020 - Criteria
KQ 1
Population:
Individuals with hypertension:
Untreated or treated and partially controlled … Study Design:
Comparative studies (randomized controlled trials, quasi-randomized controlled trials … This search will be conducted in MEDLINE and the Cochrane Central Register of Controlled Trials. … Thus, randomized controlled trials will be graded as good, fair, or poor and observational studies will … trial.pt.
10
controlled clinical trial.pt.
11
randomized controlled trials/
12
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gerd-disposition-120104.pdf
April 01, 2011 - Had they been controlled on meds
or not responding? … This
review of asthma includes all randomized controlled trials up to the
cutoff date. … Because of the paucity of patients and
randomized controlled trials evaluating asthma outcomes with … Treating heartburn in symptomatic nonerosive
GERD - A multicenter, double-blind, placebo controlled, … Also, controlled studies have not demonstrated a change
in the prevalence of Barrett’s esophagus or
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol.pdf
January 01, 2024 - in
a country rated very high)
N/A
Study Design and
Other Criteria
All KQs:
• Randomized controlled … To be considered well-controlled, comparative NRSIs will have to account for confounding
by age, stage … A cohort study of summary reports of
controlled trials. JAMA. Mar 9 1990;263(10):1401-5. … trial'/exp OR 'phase 3':ti,ab OR
'phase iii':ti,ab OR random*:ti,ab OR RCT:ti,ab)
13 'controlled … ' OR 'non
controlled' OR uncontrolled OR noncontrolled OR 'phase 2' OR 'phase two' OR 'phase ii') NEXT
-
effectivehealthcare-admin.ahrq.gov/products/diabetic-neuropathy/research-2017
April 01, 2020 - reviews, we searched for primary studies using PubMed®, Embase®, and the Cochrane Central Register of Controlled … Methods
For the prevention of DPN complications, we included a systematic review of primary randomized controlled … treatment of DPN symptoms, we included a systematic review of primary parallel or crossover randomized controlled
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-e-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
September 20, 2022 - Randomized
N Analyzed Intervention Duration (Weeks) Funding Source
Hussain, 2021
Pakistan
Placebo-controlled … Placebo 12 Hospital
Langford, 2013
UK, Czech Republic, Canada, Spain, France
Placebo-controlled
Good
-
effectivehealthcare-admin.ahrq.gov/products/epilepsy-medicine/research-protocol
December 01, 2019 - Quantitative Analysis
Randomized controlled trials (RCTs) will be pooled separately from observational … To assess study design, we will record if the study was a randomized controlled trial or an observational … Controlled Clin Trials 1986;7:177-188.
Follman D, Elliot P, Suh I, et al. … Cross-Sectional Studies/
Or/1-12
randomized controlled trial.pt. … controlled clinical trial.pt.
randomized.ab.
placebo.ab.
drug therapy.fs.
randomly.ab.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/treatment-outcomes-chronic-kidney-rapid-research.pdf
July 21, 2024 - The search strategies used a combination of medical subject headings (i.e.,
controlled vocabularies) … trials
● Non-controlled interventional trials
● Controlled and non-controlled observational studies … Publication
dates
● 2014 – May 2024 for RCTs and controlled
observational studies
● 2019 - 2024 … Risk of Bias assessments:
For primary randomized controlled trials (RCTs), the Cochrane Risk of Bias … One high quality
non-randomized controlled trial showed a significant reduction of IL1β28.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
March 01, 2012 - Peer Reviewer #2
Methods “Controlled clinical trials could be pooled as could controlled
observational … Suggest: Controlled clinical trials could
be pooled and controlled observational studies could be pooled … Comparison of levetiracetam and controlled-release
carbamazepine in newly diagnosed epilepsy. … levetiracetam was compared
with controlled-release carbamazepine. … receiving
levetiracetam compared to controlled release CBZ.