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1. Considering the Range of Decision-Relevant Effects (ppt file)
   effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-choosing-outcomes.ppt
   June 01, 2012 - The second is to consider the inclusion of outcomes from all five domains. … The third is to consider to which group the outcomes of testing are most relevant. … To illustrate this point, this module will consider a broad range of outcomes. … A broader review may consider the effectiveness of CT angiography, and the investigators would consider … Consider to whom the desired outcomes are most relevant.

2. Considering the Range of Decision-Relevant Effects (ppt file)
   effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-choosing-outcomes.ppt
   June 01, 2012 - The second is to consider the inclusion of outcomes from all five domains. … The third is to consider to which group the outcomes of testing are most relevant. … To illustrate this point, this module will consider a broad range of outcomes. … A broader review may consider the effectiveness of CT angiography, and the investigators would consider … Consider to whom the desired outcomes are most relevant.

3. More information is needed on the long-term effects of antipsychotic therapy in older adults. Please consider new research in the benefits and harms of treating patients with atypical antipsychotics. | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/more-information-is-needed-on-the-long-term-effects-of-antipsychotic-therapy-in-older-adults-please-consider-new-research-in-the-benefits-and-harms-of-treating-patients-with-atypical-antipsychotics
   November 01, 2017 - Please consider new research in the benefits and harms of treating patients with atypical antipsychotics … Please consider new research in the benefits and harms of treating patients with atypical antipsychotics … Who do you think we should contact as we consider your nomination? … Please consider new research in the benefits and harms of treating patients with atypical antipsychotics … more-information-is-needed-on-the-long-term-effects-of-antipsychotic-therapy-in-older-adults-please-consider-new-research-in-the-benefits-and-harms-of-treating-patients-with-atypical-antipsychotics

4. Our topic of nomination is Postpartum Hemorrhage. The following is a list of clinical questions practitioners consider when managing such cases: • What should be considered in the initial evaluation of a patient with excessive bleeding in… | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/our-topic-of-nomination-is-postpartum-hemorrhage-the-following-is-a-list-of-clinical-questions-practitioners-consider-when-managing-such-cases-what-should-be-considered-in-the-initial-evaluation-of-a-patient-with-excessive-b
   November 01, 2017 - The following is a list of clinical questions practitioners consider when managing such cases: • What … question, or set of related questions, about a health care test or treatment that this program should consider … The following is a list of clinical questions practitioners consider when managing such cases: What … The following is a list of clinical questions practitioners consider when managing such cases: • What … our-topic-of-nomination-is-postpartum-hemorrhage-the-following-is-a-list-of-clinical-questions-practitioners-consider-when-managing-such-cases-what-should-be-considered-in-the-initial-evaluation-of-a-patient-with-excessive-b

5. Ebell_Presentation_REVISED_FINAL (pdf file)
   effectivehealthcare-admin.ahrq.gov/sites/default/files/use_of_handheld_ebell_presentation.pdf
   January 01, 2009 - • Usefulness   • Clinical  context   • Other  factors   Slide  17:  Factors  to  Consider … Slide  19:  Factors  to  Consider  when  Evaluating  HDST   • Usefulness  =  (Relevance … than  Pneumonia   Severity  Index  (20  variables)   Slide  20:  Factors  to  Consider … Monitor:  4-­‐7  points   • Treat:  >  7  points   Slide  23:  Factors  to  Consider … Slide  25:  Factors  to  Consider  when  Evaluating  HDST   • Other  factors:  

6. AHRQ Slide Template 2009 (ppt file)
   effectivehealthcare-admin.ahrq.gov/sites/default/files/selecting-evidence.ppt
   January 01, 2010 - Comparative effectiveness reviews should always consider including observational studies. … Reviewers must consider whether or not the risk of bias can be fully assessed. … Thus, reviewers often need to consider setting criteria to screen OSs for inclusion. … The default strategy for CERs should be to consider including observational studies (OSs). … In assessing benefits, reviewers should consider two questions: 1.

7. AHRQ Slide Template 2009 (ppt file)
   effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
   January 01, 2010 - Comparative effectiveness reviews should always consider including observational studies. … Reviewers must consider whether or not the risk of bias can be fully assessed. … Thus, reviewers often need to consider setting criteria to screen OSs for inclusion. … The default strategy for CERs should be to consider including observational studies (OSs). … In assessing benefits, reviewers should consider two questions: 1.

8. Chapter 3: Choosing the Important Outcomes for a Systematic Review of a Medical Test | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-outcomes/methods
   October 01, 2019 - Consider inclusion of outcomes in all five domains: clinical management effects; direct test effects; … Consider to which group the outcomes of testing are most relevant. … The authors of this review did not consider the costs of the test to the patient as an outcome. … A broader review may consider the effectiveness of CT angiography, and the investigators would consider … Consider to which group the outcomes of testing are most relevant.

9. RENAL MASS AND LOCALIZED RENAL CANCER *the following questions are recommended to address the healthcare tests and/or treatments this program should consider: • What indicators can be used to predict malignancy and/or aggressiveness of… | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/renal-mass-and-localized-renal-cancer-the-following-questions-are-recommended-to-address-the-healthcare-tests-andor-treatments-this-program-should-consider-what-indicators-can-be-used-to-predict-malignancy-andor-aggressivene
   November 01, 2017 - following questions are recommended to address the healthcare tests and/or treatments this program should consider … question, or set of related questions, about a health care test or treatment that this program should consider … following questions are recommended to address the healthcare tests and/or treatments this program should consider … Harms or side effects from testing and/or treatment are also very important to consider. … following questions are recommended to address the healthcare tests and/or treatments this program should consider

10. Methods Guide for Medical Test Reviews Chapter 3 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-outcomes_methods.pdf
    July 01, 2012 - • Consider to which group the outcomes of testing are most relevant. … We consider a broad range of outcomes to illustrate how these may affect the balance of the benefits … The authors of this review did not consider the costs of the test to the patient as an outcome. … A broader review may consider the effectiveness of CT angiography, and the investigators would consider … • Consider to which group the outcomes of testing are most relevant.

11. Ced-Appendix-3 (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
    June 24, 2022 - Duke-M Data Need to consider adequacy with which relevant information for the intended use is documented … FDA Data Consider whether sufficient data elements are available to adjust for confounding factors that … whether use of an active comparator improves the validity of the study FDA Design Consider whether … NAM2019 Questions to consider regarding participant safety and investigator control of treatments in … factors that may impact the exposure or outcomes of interest; FDA Data_sufficiency Consider whether

12. Chapter 7: Grading a Body of Evidence on Diagnostic Tests | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-grading/methods
    December 01, 2019 - Principles: Reviewers grading the strength of a body of evidence on diagnostic tests should consider … EPCs consider “The extent to which all aspects of a study’s design and conduct can be shown to protect … When assessing the strength of an evidence base, systematic reviewers should consider four principle … It is worth noting that EPCs consider some aspects of directness separately as described in Chapter 6 … Reviewers should carefully consider which accuracy outcomes are linked to clinical outcomes.

13. Assessing the Risk of Bias in Systematic Reviews of Health Care Interventions (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-risk-of-bias.pdf
    December 01, 2017 - Consider Many Sources of Bias • When selecting risk of bias categories, consider: ► Bias arising in … Many Sources of Bias When selecting risk of bias categories, consider bias arising in the randomization … the impact of the major study limitations identified and how they may interact • Consider conducting … Consider and conduct, as appropriate, additional quantitative or qualitative sensitivity analyses or … bias on effect estimate (when possible) • When summarizing evidence, consider conducting sensitivity

14. Prioritization and Selection of Harms for Inclusion in Systematic Reviews (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-selection-harms-systematic-reviews.pdf
    February 01, 2018 - Consider composite harms endpoints 7. Check diagnostic tests for imprecision or insensitivity 8. … EPC authors consider this one of many acceptable processes but would consider more than 7 total outcomes … There are three main types of important harms to consider including. … Consider Composite Adverse Events (II) Two composite adverse events are particularly useful to consider … Consider Composite Adverse Events (I) 6. Consider Composite Adverse Events (II) 7.

15. Methods Guide for Medical Test Reviews Chapter 7 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-grading_methods.pdf
    July 01, 2012 - Principles: Reviewers grading the strength of a body of evidence on diagnostic tests should consider … EPCs consider “The extent to which all aspects of a study’s design and conduct can be shown to protect … When assessing the strength of an evidence base, systematic reviewers should consider four principle … Systematic reviewers need to carefully consider which of these accuracy outcomes to assess based on … Reviewers should carefully consider which accuracy outcomes are linked to clinical outcomes.

16. Disposition of Comments Report for Comparative Effectiveness Review No. 131 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
    February 25, 2014 - We did not consider 6-week data. … Consider including in Report. … Consider including in report. … Consider including in report. … Please consider inclusion of this safety data.

17. For patients with fecal incontinence (especially women who sustained injury from forceps delivery that now manifests as fecal incontinence in advanced age), what permanent, reliable and effective treatments are available to return this… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/for-patients-with-fecal-incontinence-especially-women-who-sustained-injury-from-forceps-delivery-that-now-manifests-as-fecal-incontinence-in-advanced-age-what-permanent-reliable-and-effective-treatments-are-available-to-retu
    November 01, 2017 - question, or set of related questions, about a health care test or treatment that this program should consider … Biofeedback is not effective and does not consider the emotional toll upon the patient. … The treatment must consider the psychological effect on the patient Appropriateness for EHC Program

18. Integrating Bodies of Evidence: Existing Systematic Reviews and Primary Studies | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/integrating-evidence/methods
    December 01, 2019 - Anyone who makes decisions concerning the provision of clinical care should consider this report in the … Some organizations would also consider whether the review was produced by a reputable source, and do … It is also important to consider the study design(s) included in the existing review. … consider when using existing systematic reviews. … The data synthesis will need to consider the impact of the new analysis or new methods.

19. Topic Nomination: Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia 1.Questions to Consider 1. What is the comparative efficacy and effectiveness of currently available and emerging treatments for lower urinary tract… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/topic-nomination-lower-urinary-tract-symptoms-secondary-to-benign-prostatic-hyperplasia-1questions-to-consider-1-what-is-the-comparative-efficacy-and-effectiveness-of-currently-available-and-emerging-treatments-for-lower-uri
    November 01, 2017 - Topic Nomination: Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia 1.Questions to Consider … question, or set of related questions, about a health care test or treatment that this program should consider … Nomination: Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia 1.Questions to Consider … Topic Nomination: Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia 1.Questions to Consider … topic-nomination-lower-urinary-tract-symptoms-secondary-to-benign-prostatic-hyperplasia-1questions-to-consider

20. Cer-235-Pharma-Nonpharm-Ptsd-Update-Appendix-G-1 (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-235-pharma-nonpharm-ptsd-update-appendix-g-1.xlsx
    November 12, 2020 - High: • Significant potential for biased findings on the primary outcome and timepoint of interest • Consider … Medium-High: • Likely potential for biased findings on the primary outcome and timepoint of interest • Consider … Medium: • Possible potential for biased findings on the primary outcome and timepoint of interest • Consider … findings on the primary outcome and timepoint of interest1 or more criteria not satisfied, resulting in • Consider … " Low: • Very low potential for biased findings on the primary outcome and timepoint of interest • Consider