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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/trauma-interventions-maltreatment-child_research-protocol.pdf
    January 12, 2012 - coercion of any child to engage in, or assist any other person to engage in, any sexually explicit conduct … or simulation of such conduct for the purpose of producing a visual depiction of such conduct; or … We will also conduct an updated literature search (of the same databases searched initially) concurrent … Examples of such major flaws include errors in conduct or analysis. … or simulation of such conduct for the purpose of producing a visual depiction of such conduct; or
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-update_research-protocol.pdf
    June 06, 2017 - • To conduct a systematic review and meta-analysis of the efficacy, comparative effectiveness, and … Methods The Evidence-based Practice Center (EPC) will conduct the review based on a systematic review … to Answer the Key Questions To identify new primary research studies meeting our criteria we will conduct … We expect to conduct random effects model meta-analyses of comparative studies, if they are sufficiently … The exact methodology to conduct the network meta-analyses will be determined based on the available
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
    November 01, 2013 - In some cases, reviewers may be able to conduct a meta-analysis to provide a quantitative estimate of … For each included study, conduct a design-specific risk of bias (RoB) assessment (low, moderate, high … When appropriate, conduct a RoB rating separately for specific outcomes in a study. … The GRADE working group has developed detailed guidance in many areas, created software to conduct this … • Study conduct.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/quality-gap-palliative-hospice_research-protocol.pdf
    June 27, 2011 - We will also conduct focused searches and separate analyses for QI studies in hospice care and nursing … that interventions for cancer pain have much stronger evidence than for other conditions, we will conduct … We will abstract details about the study design and conduct and about the population, intervention( … If necessary, we will add criteria to assess unique aspects of the conduct of studies on a given topic … We plan to conduct subgroup analyses for hospice care and for nursing home settings. F.
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
    May 14, 2010 - In 2008, the RAND EPC was asked to conduct an assessment of the need to update the original report. … For the second prong of our approach, we will conduct three main searches. … The reviewers will then conduct a second round of screening to ascertain which articles meet the inclusion … described above, for comparisons for which we are able to identify three or more outcomes, we will conduct … For pooled analysis, we will assess heterogeneity and conduct sensitivity analysis.
  6. Anxiety in Children (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/anxiety-children_research-protocol.pdf
    September 12, 2016 - Substance abuse § Autism § Obsessive-compulsive disorder (OCD) § Oppositional defiant disorder (ODD) § Conduct … Methods To conduct this systematic review, the Evidence-based Practice Center (EPC) will follow the … An experienced librarian will conduct the search. … In addition, we will conduct sensitivity analyses whenever different approaches or assumptions are in … Technical Experts do not conduct analysis of any kind nor do they contribute to the writing of the report
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/skin-cancer_research-protocol.pdf
    August 10, 2016 - Methods The Evidence-based Practice Center (EPC) will conduct the review based on a systematic review … Searching for the Evidence: We will conduct literature searches of studies in PubMed, the Cochrane Central … We expect to conduct random effects model meta-analyses of comparative studies, if they are sufficiently … We also plan to conduct a network meta-analysis to compare all treatment alternatives across studies … The exact methodology to conduct the network meta-analysis has not yet been determined, but we will
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
    July 01, 2012 - assessing risk of bias in studies evaluating medical tests—systematic error resulting from design, conduct … set of patients may not be the same as in the original study. 5-4 Elements of study design and conduct … designed specifically for diagnostic accuracy studies and 21 provided guidance for interpretation, conduct … (Yes/No/Unclear) Could the conduct or interpretation of the index test have introduced bias? … (Yes/No/Unclear) Could the reference standard, its conduct, or its interpretation have introduced bias
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/clinical-pathway-methods-report.pdf
    December 01, 2018 - Conduct a rapid evidence review. … Conduct targeted rapid reviews for clinical questions that arose during the initial review. … Conduct a quality assurance review and finalize pathway content and design. … The following section outlines the strategy that was used by ECRI Institute to conduct the additional … Conduct a rapid review of existing guidelines and pathways 4 12 3 29 60 60 16 21 205 4.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-genetic.ppt
    June 01, 2012 - PowerPoint Presentation Challenges in and Principles for Conducting Systematic Reviews of Genetic Tests Used as Predictive Indicators Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Medical Test Reviews Methods Guide www.ahrq.gov Challenges in and Principles for Conducting…
  11. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-genetic.ppt
    June 01, 2012 - PowerPoint Presentation Challenges in and Principles for Conducting Systematic Reviews of Genetic Tests Used as Predictive Indicators Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Medical Test Reviews Methods Guide www.ahrq.gov Challenges in and Principles for Conducting…
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_research-protocol.pdf
    January 27, 2012 - impaired); (3) recurrent alcohol-related legal problems (e.g., arrests for alcohol-related disorderly conduct … We will conduct quality checks to ensure that the known studies (i.e., studies included in the previous … Adults English language Publication date from 1970 to [date of search] We will not simply conduct … We will conduct an updated literature search (of the same databases searched initially) concurrent with … For each meta-analysis, we will conduct sensitivity analyses by adding studies excluded for having high
  13. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
    December 04, 2015 - conduct!disorders.! … conduct! disorders,!including!conduct!disorder,!oppositional!defiant!disorder,!intermittent! … conduct!disorders.! •! Obsessive6compulsive!disorder.! •! Substance!use!disorder.! •! Major!and! … conduct!disorder_!ED!=!eating!disorder_!FDA!=! Food!and!Drug!Administration_!FGA!=!first6generation! … $conduct$disorder*.tw,kf.$ 45.$cyclothymi*.tw,kf.$ 46.
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth_research.pdf
    January 01, 2020 - Conduct multisite studies to improve applicability and ensure power and precision. 13. … Conduct larger trials of health system interventions. 14. … o Conduct multisite studies to improve applicability and ensure power and precisions. … Conduct multisite studies to improve applicability and assure power and precision. 13. … Conduct larger trials of health system interventions. 14.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/breastfeeding_research-protocol.pdf
    January 01, 2020 - support breastfeeding are quite diverse and often complex.32-34 The purpose of this review is to conduct … literature focused on the maternal health benefits of breastfeeding has grown.1, 37-39 This review will conduct … We will conduct two separate search strategies, one for KQ1 and a second for KQ2. … If the new studies are likely to change the conclusions, we will conduct a new quantitative synthesis … In order to maintain a consistent approach, we will conduct a new SOE for each outcome and not use SOE
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-pregnant-protocol.pdf
    August 24, 2023 - Literature Search Strategies to identify primary studies for all KQs We will conduct full literature … The team will conduct two or more rounds of pilot screening. … Data Extraction and Data Management We will extract data and conduct risk of bias assessments directly … Methods / Data Extraction and Data Management We will extract data and conduct risk of bias … For studies meeting criteria for full data synthesis, we will extract data and conduct risk of bias
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-applicability_methods.pdf
    July 01, 2012 - Comprehensive information about the general conduct of reviews is available in the AHRQ Evidence-based … The conduct and synthesis of the findings will require 6-3 a method of tracking and describing … − Model cut-offs and conduct sensitivity analyses. Comparator Use of gold standard vs. … Reviews must identify these factors ahead of time and justify when to “split” questions or to conduct … effects on applicability when population characteristics change in ways that influence ability to conduct
  18. effectivehealthcare.ahrq.gov/sites/default/files/grading.ppt
    January 01, 2013 - systems incorporate not only study design but also many other facets of the evidence, including study conduct … Strength of Evidence Four Required Domains: Risk of Bias Concerns both study design and study conduct … Risk of bias incorporates both study design and study conduct. … Any flaw (reported or unreported) in the trial design or conduct will likely be replicated at every center … Guiding Principles: Risk of Bias The risk of bias based on the design and conduct of the available studies
  19. Ced-Appendix-3 (xls file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
    June 24, 2022 - the classification of exposed and unexposed person-time is free of “immortal time" Grace 5.1 Design Conduct … process and provide consent when applicable; organization adheres to ethical standards for responsible conduct … CMS Reporting In addition, thorough documentation of the conduct of the research, particularly study … upon request a log of any researcher or researchers who have significant involvement in the design or conduct … the classification of exposed and unexposed person-time is free of “immortal time" GRACE 5.1 Design Conduct
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/AI-tools-protocol.pdf
    August 15, 2023 - labor- and time- intensive steps in evidence synthesis methodology, the uptake of automation in the conduct … of the Review This living review will summarize the evidence on the use of ML and AI tools in the conduct

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