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161. Research Protocol (Amended): Treatment of Acute Pain--An Evidence Map (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-protocol-amended.pdf
     June 10, 2018 - We will conduct a search to identify systematic reviews on pain treatments for acute pain for the priority … We will conduct grey literature searching to identify guidelines not found through bibliographic database … We will conduct additional searches for original research for topics not addressed by published systematic

162. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2023 Update of the Evidence Base for the PTSD Trials Standardized Data Repository (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2023-update-executive-summ.pdf
     January 01, 2023 - Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2023 Update of the Evidence Base for the PTSD Trials Standardized Data Repository Systematic Review Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2023 Update of the Evidence Base for the PTSD …

163. Disposition of Comments_Comparative Effectiveness Review No. 257_Schedule of Visits and Televisits for Routine Antenatal Care: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-257-antenatal-care-disposition-comments.pdf
     June 28, 2022 - Disposition of Comments_Comparative Effectiveness Review No. 257_Schedule of Visits and Televisits for Routine Antenatal Care: A Systematic Review Comparative Effectiveness Review Disposition of Comments Report Title: Schedule of Visits and Televisits for Routine Antenatal Care: A Systematic Review …

164. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 - EPCs systematically review the relevant scientific literature on topics assigned to them by AHRQ and conduct … Fourth, it may be infeasible or highly resource-intensive to conduct an RCT, for example to examine … Assessments of risk of bias in NRSIs should therefore focus on study design, conduct, and analysis,43 … It may also be appropriate to conduct sensitivity analyses that exclude high-risk of bias NRSIs to avoid … Conduct of the SR When NRSIs are included, 10.

165. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 - EPCs systematically review the relevant scientific literature on topics assigned to them by AHRQ and conduct … Fourth, it may be infeasible or highly resource-intensive to conduct an RCT, for example to examine … Assessments of risk of bias in NRSIs should therefore focus on study design, conduct, and analysis,43 … It may also be appropriate to conduct sensitivity analyses that exclude high-risk of bias NRSIs to avoid … Conduct of the SR When NRSIs are included, 10.

166. Mixed MethodsReview -Integrating Palliative Care with Chronic Disease Management in Ambulatory Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/palliative-care-research-amended-protocol.pdf
     November 21, 2019 - Individual Studies: Methodologic risk of bias is not relevant for qualitative research, so we will conduct … searches for each type of literature, will then combine these to answer each of the key questions and conduct … We will conduct meta-analyses when there are sufficient data (at least three studies) and studies are … If substantial heterogeneity is found, we will conduct sensitivity analyses, when applicable, as well … Integrative synthesis methods: We will conduct an integrative review of quantitative, qualitative

167. Management of Suicidal Thoughts and Behaviors in Youth: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-exe-sum.pdf
     April 01, 2025 - Management of Suicidal Thoughts and Behaviors in Youth: A Systematic Review Systematic Review Management of Suicidal Thoughts and Behaviors in Youth: A Systematic Review Executive Summary Main Points • The current body of evidence is derived primarily from racially and ethnically diverse f…

168. Rapid-Reviews-End-User White-Paper (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-reviews-end-user_white-paper.pdf
     April 01, 2016 - EPCs systematically review the relevant scientific literature on topics assigned to them by AHRQ and conduct … that produced the report (and end- user relationship with that organization), and methods used to conduct … End-users spoke about needing to conduct supplemental searches and analyses themselves in order to … Methodological standards for the conduct of near Cochrane Intervention Reviews Cochrane Collaboration … Did you conduct additional analyses or gather additional information? d.

169. Transparency of Reporting Requirements: Management of Infertility (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-infertility_research-protocol.pdf
     September 02, 2016 - Searching CT.gov We will conduct a search in CT.gov for each KQ with the assistance of our search … We will conduct two searches, a broad search using the basic interface and a more specific search using … For unmatched studies, we will conduct a manual match using the condition, intervention, sample size

170. Executive summary_Systematic Review: Fiber Intake and Laxation in People With Normal Bowel Function (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fiber-intake-final-executive-summary.pdf
     July 01, 2025 - Executive summary_Systematic Review: Fiber Intake and Laxation in People With Normal Bowel Function Systematic Review Fiber Intake and Laxation in People With Normal Bowel Function Executive Summary Main Points • Association of increasing dietary fiber intake and laxation outcomes (all …

171. In the area of autism research, the vast majority of clinical trials conducted to date have addressed only the questions of how an individual treatment compares to a placebo. Extremely few studies have been conducted that make head-to-… | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/pin-the-area-of-autism-research-the-vast-majority-of-clinical-trials-conducted-to-date-have-addressed-only-the-questions-of-how-an-individual-treatment-compares-to-a-placebo-extremely-few-studies-have-been-conducted-that-mak

172. Executive Summary_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2024 Update of the Evidence Base for the PTSD Trials Standardized Data Repository (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-final-report-update-2024-executive-summ.pdf
     January 01, 2024 - Executive Summary_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2024 Update of the Evidence Base for the PTSD Trials Standardized Data Repository Systematic Review Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2024 Update of the Evidence …

173. Disposition of Comments: Comparative Effectiveness Review No. 238 Cervical Ripening in the Outpatient Setting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-outpatient-setting-comments.pdf
     March 22, 2021 - We initially hoped to be able to conduct subgroup analyses based on US vs. non-US studies.

174. Surveillance Report: Masks for Prevention of COVID-19 in Community and Healthcare Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-prevention-covid-surveillance-report.pdf
     July 17, 2020 - Masks included N95 respirators, surgical masks, or cloth face coverings, and the study did not conduct

175. Quantitative Synthesis: Chapter 1. Decision To Combine Trials (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-1.pdf
     July 01, 2019 - • Methodological heterogeneity relates to study methods (e.g., study design, measures, conduct). ►

176. Methods White Paper: Improving the Utility of Evidence Synthesis for Decision Makers in the Face of Insufficient Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/improving-utility-evidence-synthesis-white-paper.pdf
     April 01, 2021 - EPCs systematically review the relevant scientific literature on topics assigned to them by AHRQ and conduct … Conclusion: Throughout early scoping, protocol development, review conduct, and review presentation, … However, if potential bias in design or conduct of the study leads to insufficient evidence, authors … However, in the conduct of the study, reviewers may discover that flaws in the conduct of the study … Notably, in some instances, the suggested approaches may not be logistically feasible during the conduct

177. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
     July 13, 2011 - We will also conduct an updated literature search (in PubMed, the Cochrane Library, PsycINFO, IPA, … Because we do not have access to individual patient data, we will not conduct any subgroup analyses.

178. CER 221 Disposition of Comments: Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-comments_0.pdf
     October 11, 2019 - This is also the reason we didn’t conduct network meta-analysis or pool systemic vs inhaled CS per … We did not conduct a network meta-analysis. … : No We didn’t conduct network meta-analysis. … : No We didn’t conduct network meta-analysis. … Due to heterogeneity, we didn’t conduct network meta- analysis.

179. Making Healthcare Safer IV_Rapid Response: Reducing Adverse Drug Events Related to Anticoagulant Use in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-high-risk-drugs-rapid-response.pdf
     January 01, 2024 - Making Healthcare Safer IV_Rapid Response: Reducing Adverse Drug Events Related to Anticoagulant Use in Adults Making Healthcare Safer IV Reducing Adverse Drug Events Related to Anticoagulant Use in Adults Rapid Response Main Points 1. Anticoagulation medications help prevent life-threatening events such…

180. Discerning the Perception and Impact of Patients Involved in Evidence-based Practice Center Key Informant Interviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/key-informant-interviews-research.pdf
     December 19, 2017 - EPCs systematically review the relevant scientific literature on topics assigned to them by AHRQ and conduct … Additionally, conduct an initial screening process to ensure that the patient/patient advocate has the … Since the EPCs conduct projects on an ongoing basis, you might be asked to participate on another systematic … • After we conduct individual interviews with each of the participants, we will bring all of you … CONDUCT INTERVIEW: We would like to understand your involvement in the Evidence-based Practice Centers