-
effectivehealthcare-admin.ahrq.gov/products/transparency-neuropathy/research-protocol
June 01, 2021 - reporting bias such as publication bias and outcome reporting bias, may lead to biased and flat out wrong conclusions … What is the impact on the conclusions of the EPC report with and without the information from ClinicalTrials.gov … Finally, the full team will consider if the final conclusions are influenced by any indication of reporting … comparison) between results from ClinicalTrials.gov and published literature, in terms of direction of conclusions … Finally, the full team will consider if the final conclusions are influenced by any indication of reporting
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/stem-cell-children_surveillance.pdf
October 29, 2012 - October 29, 2012
Key Findings:
• KQ1, 2, 3, 4, 5 and 6 up to date
• Expert opinion: conclusions … This decision was based on
the fact that in the original CER almost all the conclusions were rated as … Conclusions were drawn based on four category scheme:
• Original conclusion is still up to date and … the four CER conclusions.
6
4. … Summary Table
Conclusions from
CER’s Executive
Summary
Update
literature
search
results
-
effectivehealthcare-admin.ahrq.gov/products/venous-ulcers-treatment/research
December 01, 2019 - showed more rapid healing of venous ulcers (moderate strength of evidence).We could not draw definitive conclusions … Conclusions
These findings do not mean that the interventions do not have value. … the risk of bias and lack of adequate sample size prevented us from establishing statistically valid conclusions … The absence of these critical design elements limited our ability to draw conclusions. … development of research wound healing networks to collect sufficient number of patients to produce valid conclusions
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
January 01, 2013 - SSRIs
Original release date: April 2012
Surveillance Report: January 2013
Key Findings:
• All conclusions … For example, would the potential changes to
the conclusions involve refinement of original estimates … The three experts felt all the conclusions were either up to date or did not know. … The few new studies we identified supported the conclusions of the original CER. … Thus, there is no need to
update the CER at this time.
4
Table 1: Summary Table
Conclusions
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/dyspnea-advanced-cancer-summary-1.pdf
November 01, 2020 - The evidence was insufficient to draw conclusions (2 RCTs, 287 patients).
4
Key … • Few studies reported harms, which limited our ability to draw conclusions
Pharmacological interventions … Nonpharmacological compared with pharmacological:
The evidence was insufficient to draw any conclusions … Implications and Conclusions
In conclusion, a variety of nonpharmacological interventions, including … Main Points
Background and Purpose
Methods
Results
Strengths and Limitations
Implications and Conclusions
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
January 01, 2007 - Conclusions
Summary Table A presents the main conclusions from
published evidence regarding the comparative … There were too few comparative studies of
nateglinide to draw conclusions. … There
were too few comparisons for nateglinide to draw
conclusions.
All-cause mortality. … Other comparisons
between drugs had too few studies to draw conclusions. … There were too few comparisons for
nateglinide to draw conclusions.
2.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/musculoskeletal-complaints-tests-children_surveillance.pdf
January 08, 2013 - Original release date:
March, 2012
Surveillance Report:
March, 2013
Key Findings:
- All conclusions … For example, would the potential changes to
the conclusions involve refinement of original estimates … With the exception of one
conclusion, the respondents felt all conclusions were up to date or did not … Again, only four new studies met inclusion criteria, and these did not change
any of the conclusions … Thus, no update of the CER is warranted at this
time.
5
Table 1: Summary Table
Conclusions From
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer18-heart-disease-ace-inhibitor-arb-executive.pdf
October 01, 2009 - 3
Conclusions
Table A provides an aggregated view of the strength of
evidence and brief conclusions … therapy for stable ischemic heart disease
Strength of
Key Question evidence Conclusions
KQ1. … therapy for stable ischemic heart disease
Strength of
Key Question evidence Conclusions
KQ1b. … therapy for stable ischemic heart disease
Strength of
Key Question evidence Conclusions
KQ1d. … therapy for stable ischemic heart disease
Strength of
Key Question evidence Conclusions
KQ2.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/glaucoma-treatment_surveillance.pdf
January 01, 2013 - compared the effectiveness and safety of
existing treatments but none sufficiently challenged the
conclusions … ................................................................ 1
2.5 Compilation of Findings and Conclusions … To assess the conclusions in terms of the evidence that they might need updating, we used the 4-category … For example, would the potential changes to the conclusions
involve refinement of original estimates … It will
New Evidence:
Conclusions From CER
Executive Summary
Is this conclusion
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-disposition-comments.pdf
August 29, 2023 - The conclusions are appropriate.
Thank you for your comments. … The conclusions are appropriate.]
Thank you. … The conclusions are appropriate.]
Thank you. … The conclusions are appropriate.]
Thank you. … The conclusions are appropriate.]
Thank you.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antipsychotics-children-surveillance-150120.pdf
October 01, 2014 - We compared the conclusions of the included abstracts to the
conclusions of the original CER and surveillance … Conclusions on comparative effectiveness of FGAs vs. … The attached document includes a table highlighting the conclusions from the original report, conclusions … Conclusions From Original Review Conclusions from Prior Surveillance
Assessment (Nov 2012)
SRC Literature … number of studies
supporting other original
report conclusions.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/autism-adolescents_surveillance.pdf
July 01, 2014 - However, the limited
new evidence is unlikely to change the conclusions of the original report. … • The original report conclusions for all Key Questions in this report are
still valid. … We compared the conclusions of the included abstracts to the conclusions of the original
CER and assessed … expert opinions to identify qualitative signals about the currency of conclusions. … The three experts felt all the conclusions were up to date.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_surveillance.pdf
August 01, 2012 - November, 2011
Surveillance Report 2nd Assessment: August 2012
Key Findings 1st Assessment:
• All conclusions … For example, would the potential changes to
the conclusions involve refinement of original estimates … The findings not included in the original report supported the conclusions of the
original report. … Up-to-date Up-to-date
6
Conclusions
From CER
Executive
Summary
RAND Literature
Search … Do Not Know
Overall Conclusions:
Improvements in bone mineral content vs.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_clinician.pdf
May 01, 2011 - comparing
multimodal approaches with standard care were limited, and evidence is
insufficient to permit conclusions … Conclusions
Overall, there is limited evidence about the comparative
effectiveness, benefits, and adverse … For
systemic analgesics and several other modalities, studies are too
limited to permit conclusions … Further research is very unlikely to change
the conclusions. … Moderate: ��� Findings are supported, but further research could
change the conclusions.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/phenylketonuria_surveillance.pdf
January 15, 2013 - Original release date:
February 2012
Surveillance Report:
January 2013
Key Findings:
• All conclusions … • Several new studies were identified, but none
challenged existing conclusions. … For example, would the potential changes to
the conclusions involve refinement of original estimates … Dietary control—and reporting of dietary
New Evidence:
Conclusions From … Conclusions From
CER Executive
Summary
Is this conclusion
almost certainly still
supported by the
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/autism_surveillance.pdf
October 01, 2012 - • Conclusions are still valid for Key Questions 3 through 7. … • Conclusions are still valid for Key Questions 3 through 7. … They felt that the
majority of the CER conclusions were still valid, but some conclusions on specific … NA January 2012 - Three experts felt
conclusions still valid. … October
2012 – Two experts felt
conclusions still valid.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-261-postpartum-care-executive-summary.pdf
June 01, 2023 - o For general postpartum care (2 NRCSs) and screening (1 RCT and 2
NRCSs), no conclusions are feasible … o For screening care (1 RCT and 1 NRCS), no conclusions are feasible
because of insufficient evidence … Limitations
Although we found 64 studies for KQ 1, we were limited in our ability to make
conclusions … Implications and Conclusions
Although we found 92 studies conducted in the United States or Canada, … we were
able to make few specific conclusions.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
October 01, 2012 - Original release date:
January 2012
Surveillance Report:
October 2012
Key Findings:
- The conclusions … screening) and KQ4
(harms of monitoring), KQ6 (harms of treatment) are still
considered valid
- The conclusions … For example, would the potential changes to
the conclusions involve refinement of original estimates … Summary Table
Conclusions From CER
Executive Summary
RAND Literature
Search
FDA/ Health
Canada … Adverse event
signals should be followed
up
8
Conclusions From CER
Executive Summary
RAND
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_surveillance.pdf
December 31, 2013 - • For Key Question 2, conclusions regarding cardiovascular
morbidity and mortality are considered … • For Key Question 3, conclusions regarding other adverse events
are possibly out of date. … Conclusions
should be
updated to
reflect new
evidence. … No conclusions. No new studies identified. No issues identified. … No conclusions.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/practical-considerations.pdf
March 01, 2022 - The findings and conclusions in this document
are those of the authors, who are responsible for its … contents; the findings and conclusions do not
necessarily represent the views of AHRQ. … Conclusions ......................................................................................... … If SOE changes for
primary outcomes,
conclusions will change;
get LSR TEP input on
approaches … Conclusions
4. References