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effectivehealthcare.ahrq.gov/health-topics/rural-health-concerns
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-d.xlsx
January 01, 2023 - Ahn 2013 Grade 3 to 5 AEs Some concerns Some concerns Low Low Some concerns Some concerns some risk of … AMC0101 OS Some concerns Low Low Some concerns Low Some concerns Some concerns in 2 domains
AMC0101 … Grade 3 to 5 AEs Some concerns Low Low Some concerns Low Some concerns Some concerns in 2 domains
AMC0201 … in Domains 2 and 5
COMPASS OS Some concerns Low Low Some concerns Some concerns Some concerns Some concerns … 3 to 5 AEs Some concerns Some concerns Low Low Some concerns Some concerns Some concerns in Domains 1
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2023-update-app-g-2.xlsx
January 01, 2023 - No Probably No Probably No Some Concerns High
Asukai, 2010 Yes No Information Probably No Some Concerns … Some Concerns
Back, 2019 Yes Yes Yes Some Concerns Yes Yes Probably No NA NA Yes NA Low No 48.1% … Low No No Yes Yes Probably No Some Concerns No Probably No Probably No Some Concerns High
Bisson, 2020 … Some Concerns
Capone, 2018 No Information No Information No Some Concerns Yes Yes Probably No NA NA … Concerns
Cloitre, 2010 No Information No Information No Some Concerns Yes Yes No NA NA Yes NA Low No
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2023-update-app-g-1.xlsx
January 01, 2023 - No No Yes Yes Probably No Some Concerns Yes No No Low Some Concerns
Alon, 2022 Yes Yes No Low Yes Yes … Yes Probably No Probably No Low Some Concerns
Foa, 2022 Yes Yes No Low Yes Yes No NA NA Yes NA Low … Yes No No Low Some concerns
Fruchtman-Steinbok, 2021 Yes No Information No Some Concerns Yes Yes Probably … No No No NA NA Low Yes No No Low Some Concerns
Raabe, 2022 Yes Yes Probably No Low Yes Yes No NA NA … No No Yes (PCL) Probably Yes Probably No Some Concerns Yes Probably No Probably No Low High
Schnurr
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-app-g2-3.xlsx
January 01, 2022 - C: 30.0% (3/10) Some concerns No No No (CAPS) NA NA Low No NI NI Some concerns Some concerns
Beidel … concerns
Boggio, 2010 No information No information No information Some concerns No No information … C: 33.3% (3/9) Some concerns Yes No NA NA NA High No Probably no No Some concerns High
Bremner, 2017 … C: 51.6% (16/31) Some concerns No No No (CAPS) NA NA Low Yes No No Low Some concerns
Bryant, 2003 No … C: 40.0% (6/15) Some concerns No No No (CAPS) NA NA Low No Probably no No Some concerns Some concerns
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-app-g1.xlsx
January 01, 2022 - RoB judgement RoB rating
Alsheikh Ali, 2020 No information No information No information Some concerns … No No No NA NA Low Probably yes Probably no No Low Some concerns
Bonn-Miller, 2021 Yes Yes No Low No … No No No NA NA Low Probably yes Probably no No Low Some concerns
Jain, 2020 Yes Yes No Low Yes Yes … CPT: 38.7% (36/93) Some concerns No No No (CAPS-5) NA NA Low Yes No No Low Some concerns
Kelly, 2021 … STAIR+PE: 28% (14/50) Some concerns No No No (CAPS-5) NA NA Low Yes No No Low Some concerns
Petrakis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-appendix-c-prepub-final.xlsx
January 01, 2025 - Klein, 2021 Unclear No Yes High concerns Case-control study design Yes Yes Low concerns From Methods … Unclear Unclear High concerns None NR NR Unclear Unclear Unclear Unclear High concerns None High ROB … Notable concerns There are notable concerns about conflicts of interest for both the funder (Berthold … No notable concerns Based on no notable concerns for both funders and researchers. … No notable concerns No notable concerns identified for either funders or primary academic researchers
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-final-app-c.xlsx
January 01, 2025 - Klein, 2021 Unclear No Yes High concerns Case-control study design Yes Yes Low concerns From Methods … Unclear Unclear High concerns None NR NR Unclear Unclear Unclear Unclear High concerns None High ROB … Notable concerns There are notable concerns about conflicts of interest for both the funder (Berthold … No notable concerns Based on no notable concerns for both funders and researchers. … No notable concerns No notable concerns identified for either funders or primary academic researchers
-
effectivehealthcare.ahrq.gov/sites/default/files/ebc-challenge-2ndplace-paws.pdf
May 29, 2025 - Review your treatment plan and follow up
with your care provider if you have questions
or concerns … Next Steps for Healthy Ears:
Your healthcare team is availa-
ble to assist you with questions
or concerns
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-draft-appendi-c.xlsx
January 01, 2024 - No prespecified protocol or analysis plan Some concerns Some concerns Some concerns for bias because … No prespecification of protocol or analysis plan High NA, no harms outcomes reported Some concerns … No published protocol or prespecified analysis plan Some concerns Some concerns Some concerns for bias … None NI None NI None NI None Some concerns No information on randomization and allocation concealment … procedures Probably yes None NI None NI None NA None NA None Yes None NA None Some concerns Unclear
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-257-antenatal-care-evidence-summary.pdf
June 01, 2022 - of buy-in from
health-system leadership; a need to integrate televisits within existing
workflows; concerns … The potential benefits and harms or concerns related to televisits, as opposed to in-person
care, have … Providers also expressed concerns that implementation may be hampered
by decades of patients’ (and their … Concerns that televisits may hamper safety, quality of care, and worsen
health disparities were noted … Although providers and patients had some concerns about
reduced visit schedules and use of televisits
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
May 01, 2013 - The
SOE of evidence for safety concerns is insufficient. … Safety concerns (subgroups)
SOE=Insufficient
0 studies
Clopidogrel/aspirin vs. … Seventeen RCTs reported safety concerns. … The SOE for
safety concerns by subgroup was insufficient. … Only one observational study in the CLI population
reported safety concerns.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-final-report-update-2024-executive-summ.pdf
January 01, 2024 - o Risk of bias (RoB) was rated as low for 18 percent, some concerns for 27
percent, and high for the … o RoB was rated as low for 39 percent, some concerns for 17 percent, and
high for the remaining 44 percent … Across all 550 RCTs, RoB was rated as low RoB for 18 percent, some
concerns for 27 percent, and high … Of the 54 newly added RCTs, 44 percent were rated as high RoB, 17 percent
were rated as some concerns
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2023-update-executive-summ.pdf
January 01, 2023 - o Across all 496 RCTs, RoB was rated as low RoB for 14 percent, some
concerns for 27 percent, and high … o Of the 60 newly added RCTs, RoB was rated as low RoB for 17 percent,
some concerns for 17 percent, … Across all 496 RCTs, RoB was rated as low RoB for 14 percent, some
concerns for 27 percent, and high … Of the 60 newly added RCTs, 67 percent
were rated as high RoB, 17 percent were rated as some concerns
-
effectivehealthcare.ahrq.gov/sites/default/files/module_iv1.ppt
May 29, 2025 - .
*
Challenge: Engaging & Preparing Stakeholders
Address logistical concerns
Plan ahead
Provide … Possible strategies and tools for preparing stakeholders include:
Address logistical concerns. … disease condition
Personal experience with disease or topic
Unique policy aspects of topic
Clinical concerns … stakeholder
Providing written materials in advance
Having flexible meeting times that address logistical concerns … stakeholder
Providing written materials in advance
Having flexible meeting times that address logistical concerns
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
May 01, 2015 - Although most ankyloglossia research is focused on the
infant and breastfeeding issues, concerns beyond … Benefits of Treatments To Prevent Social
Concerns Related to Tongue Mobility
Only one poor-quality … Social Concerns Related to Tongue Mobility
With only one poor-quality comparative study, strength … Social Outcomes
Social concerns
Retrospective cohort:
1 poor16 (104)
High NA Indirect Imprecise … Understanding of the natural
history of speech concerns in children with ankyloglossia
is lacking,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced%20-appendix-2.xlsx
May 29, 2025 - Other concerns about the current process CED note a lack of transparency, problems arising from the speed … More important to focus on how and when CED should be used, before revising study requirements (concerns … Does not address the inherent ethical, logistic, and health equity concerns that CED injects when applied … Haystack Does not address the inherent ethical, logistic, and health equity concerns that CED injects … for decisions delegated to and made by FDA or shared decision making between patient and clinician Concerns
-
effectivehealthcare.ahrq.gov/sites/default/files/module-iv-skills-for-successful-engagement.pdf
May 29, 2025 - Slide 17
Challenge: Engaging & Preparing Stakeholders
§ Address logistical concerns … Possible strategies and tools for preparing stakeholders include:
§ Address logistical concerns. … as
part of their job or other official duties, investigators need to allow for related logistical
concerns … • Providing written materials in advance
• Having flexible meeting times that address logistical concerns … • Providing written materials in advance
• Having flexible meeting times that address logistical concerns
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-222-health-equity-preventive-services-comments.pdf
December 03, 2019 - Currently, there is one recommendation from the US
Preventive Services Task Force that concerns genetic … Psychologists have raised concerns about the lack of
research with various ethnic minority groups and … American
Psychological
Association
Similar concerns can be raised for those with mobility
limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-disposition-comments_0.pdf
March 03, 2025 - • Some reviewers shared the concerns that the review did not evaluate carbohydrate quality and
source … Section Comment Response
Jonathan
Clinthorne, Simply
Good Foods
Executive
Summary
We have strong concerns … Jonathan
Clinthorne, Simply
Good Foods
Results We reiterate our concerns that the results from this … Affiliation
Section Comment Response
Jonathan
Clinthorne, Simply
Good Foods
Discussion We have concerns