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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-bias-individual-studies_methods.pdf
March 01, 2012 - Systematic reviewers have the responsibility to evaluate potential
sources of bias and error if these concerns … could plausibly influence study results; we include
these concerns even if no empirical evidence exists … For instance, concerns about the choice of designs, hypotheses, and
outcomes relate as much or more … Although the Jadad scale is the most commonly used tool to assess risk of bias of RCTs,
concerns regarding … In 2005, The Cochrane Collaboration convened a group to address several concerns in the
assessment of
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cad-women-treatment_research-protocol.pdf
September 29, 2011 - What are the significant safety concerns associated with each treatment strategy (i.e., adverse
drug … What are the significant safety concerns associated with each treatment strategy (i.e., adverse
drug … What are the significant safety concerns associated with each treatment strategy (i.e., adverse
drug … effectiveness of
treatment options (Key Questions 1b, 2b, 3b) and whether there are significant safety concerns … strategies (optimal medical
therapy, PCI, or CABG), (b) modifiers of effectiveness, and (c) safety concerns
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effectivehealthcare-admin.ahrq.gov/products/registry-of-patient-registries/research-2012
September 01, 2019 - The stakeholder perspectives section highlights the major concerns and suggestions of the stakeholder … While much of the data is not health-related and therefore subject to different legal and ethical concerns … The donation of data from post-marketing studies raises concerns related to proprietary information that … Privacy concerns related to how the data in registries were gathered and stored may also exist. … The primary concerns in approving such a waiver would likely relate to the nature of the data.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_disposition-comments.pdf
May 29, 2013 - We have
fixed this uneven column spacing
Reviewer 6 Methods I have concerns about including studies … Despite these concerns we
believe that such outcomes should be
included with a nuanced description … Commentator
& Affiliation
Section Comment Response
Public
Comments -
EBIR BJ
Results I have concerns … We appreciate these comments and have
substantially revised KQ1 and the report to
respond to these concerns … An updated
future research section addresses many of
these concerns.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
March 01, 2012 - Summary
“What this data does show is that a number of neurologists and
patients with epilepsy have concerns … To not
assess this issue seems out of touch with gender research
concerns raised by the US government … As with all evidence-based reviews, we realize that
practical real world concerns of how best to use … As a result of this review, we have major
concerns with the design, development, evaluation, and use … Pellock,
M.D., American
Epilepsy Society
President 2011
General Additionally, there are concerns
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/asthma-treatment_disposition-comments.pdf
September 10, 2012 - research literature
unfortunately is not an adequate venue for properly
addressing those individual concerns … Reviewer 3 Methods Search strategies appear to be appropriate, although I had two
concerns.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-612-09-03-2013.pdf
January 01, 2013 - TND-612-09-03-2013
Topic Number(s): 0520
Document Completion Date: 02-06-2013
1
Results of Topic Selection Process & Next Steps
The topic, Interventions to Transition Children with Special Health Care Needs (CSHCN) from Pediatric
to Adult Care, is not feasible for a full systematic review due…
-
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/distributed-network-safety_research.pdf
July 01, 2009 - This design addresses the issues and concerns
noted above and supports the following capabilities: … Thus far, reports are that governance concerns remain the sticking points in initial
adoption. … Each teaching hospital has had comparable concerns regarding patient privacy and
security. … Additional concerns relate to the
release of proprietary information, such as enrollment counts and … The business case for a DRN must be clearly
articulated, and the concerns of data owners should be
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1406.pdf
September 26, 2014 - However, some experts expressed concerns over the potential for
ES-7
cardiovascular risks. … However, several experts expressed concerns
about the potential for side effects with GLP-1 receptor … Some
experts expressed concerns about the potential for cardiovascular risks. … Several experts expressed concerns over the potential for side effects with
GLP-1 receptor agonists … However, several experts expressed concerns regarding potential adverse events,
including cataracts
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/what-is-the-effectiveness-of-interventions-designed-to-support-children-in-transition-from-pediatric-care-to-adult-care-with-special-health-care-needs-ineffective-transition-planning-can-have-significant-negative-consequence
November 01, 2017 - Skip to main content
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Careers
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/registry-of-patient-registries-development_research_0.pdf
February 01, 2012 - The above discussion outlines several clear benefits as well as concerns regarding a potential
registry … owners are incentivized to participate ultimately will determine if the net benefits
outweigh the concerns … Concerns regarding
ability to publish
results
Interest in
facilitating
research
collaboration … Concerns
regarding ability
to publish
results
Concerns
regarding ability
to publish results … Several stakeholders expressed concerns about ensuring that the information provided
in the database
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1412.pdf
January 01, 2015 - Experts also expressed
concerns regarding potential adverse events, including cataracts and increased … However, several experts expressed concerns
about the potential for side effects with GLP-1 receptor … Several experts expressed concerns over the potential for side effects with
GLP-1 receptor agonists … However, several experts expressed concerns regarding potential adverse events,
including cataracts … However, some experts expressed concerns about the potential for increased physician
office visits
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-disposition-comments.pdf
August 29, 2023 - Several concerns were raised by
the EPC:
The EPC analysis in the report
followed the published protocol … These
additional analyses would be
beyond the scope of the protocol
and raise methodological
concerns
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
February 01, 2012 - These concerns were either too broad
in scope, related to very specific design flaws about which there … These concerns were
left as general recommendations for consideration and are listed below. … When evaluating shorter-term safety concerns, combining data from trials may be more feasible
because … Concerns may occur when
treatment is assigned through
random allocation. … Concerns may occur when
treatment is assigned by
investigators.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-241-wheelchair-users-disposition-comments.pdf
October 18, 2022 - Yes, however I note several concerns above including
the definition of PA, inclusion of studies that
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/head-neck-cancer_disposition-comments.pdf
May 27, 2010 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov
Published Online: May 27, 2010
1
Comparative Effectiveness Research Review Disposition of Comments Report
Research Review Title: Comparative Effectiveness and Safety of Radio…
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/single-group-studies_white-paper.pdf
January 01, 2013 - They included specific concerns about confounding,
avoidance of bias, and that sufficient data were … They included specific
concerns about confounding; avoidance of bias; and that sufficient data were
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
October 30, 2019 - concern and have added the
following to the discussion: “In
frail older patients, there may
be concerns … Regardless, I think most of the results are valid
though I had some concerns about some specific
conclusions … anticoagulation treatments, awareness of
the availability of an antidote can help alleviate
patient concerns … Peer Reviewer #2 Methods I have concerns about the criterion stated at page
16 lines 17-21: “we assumed … It did not in any way address the specific
concerns we raised.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-200-comments-post-acs.pdf
November 14, 2017 - We appreciate the concerns about
the narrowness of the eligibility
criteria. … editorials
that have taken this position have been from a small but
highly vocal group, some of these concerns … TEP #2 Clarity and
Usability
I had no concerns.