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81. Disposition of Comments_Systematic Review: Breastfeeding and Health Outcomes for Infants and Children (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-disposition-comments.pdf
    March 31, 2025 - We discuss this concern in the Applicability section of the Discussion. … We appreciate your concern.

82. Research White Paper: Outcome Measure Harmonization and Data Infrastructure for Patient-Centered Outcomes Research in Depression (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-outcome-measure-harmonization-depression.pdf
    November 01, 2020 - Because of this concern, the adverse events measure will be calculated using data captured in the EHR

83. March 3rd Impact of Healthcare Algorithms on Racial and Ethnic Disparities in Healthcare (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/impact-healthcare-algorithms-racial-ethnic-disparities-March-3.pdf
    July 01, 2023 - RED indicates there is potential for concern. … GREEN indicates there is limited potential for concern. … YELLOW indicates the potential for concern is unclear or there is not enough information with which to … ► Algorithm developers ► End-users • “Off-label” use • Scope of concern ► Traditional algorithms

84. Epstein_Respondent_Glasgow 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/interactive_media_epstein_respondent.pdf
    January 01, 2009 - Epstein_Respondent_Glasgow 1   Source:    Eisenberg  Center  Conference  Series  2009,  Translating  Information  Into  Action:  Improving  Quality  of   Care  Through  Interactive  Media,  Effective  Health  Care  Program  Web  site   (http://www.effectivehealthcar…

85. Comparative Effectiveness Review Disposition of Comments Report: Anxiety in Children (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/disposition-of-comments-cer-192-anxiety-in-children.pdf
    August 31, 2017 - point is the introduction did not mention the black box warning for antidepressants which is a concern … Reviewers can make a judgment on a case by case basis as to whether it represent a major concern. … Our final major methodological concern deals with classification of interventions, particularly inconsistencies … Affiliation Section Comment Response TEP 1 General The largest, and a quite significant, concern

86. Slide 1 (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/module_ii1.ppt
    June 01, 2011 - community organizations identifies the reintegration of drug users after incarceration as a community concern … community organizations identifies the reintegration of drug users after incarceration as a community concern

87. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_disposition-comments.pdf
    September 01, 2011 - Publication bias is not an important concern of ours with respect to this CER. … This again underscores my concern that the expressed statistical suspicion of bias, however small, will … The second issue of nascent, but growing, concern is the possible linkage of such therapy with autism

88. Technical Brief 16 Disposition of Comments Report (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/advanced-care-decision-aids_disposition-comments.pdf
    July 29, 2014 - Affiliation Section Comment Response Peer Reviewer #2 Abstract Seems that another future direction concern … But without the ACP decision aids themselves being tested/experienced, there must be concern that key … appropriate to patients in various settings working with various facilitators” to highlight this concern

89. Disposition of Comments: Technical Brief No. 38_Automated Entry Patient Generated Health Data for Chronic Conditions: The Evidence on Health Outcomes (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-38-chronic-conditions-comments.pdf
    March 01, 2021 - Is there reason for concern that a significant amount of consumer energy and time is wasted in engaging … This is a major concern. … Peer Reviewer #2 Methods In general, the definitions for health vs “non-health” outcomes is a concern … Is there any concern about financial interest in some of the studies conducted and, if so, was that … and whether those are considered aspirational, or whether they are required by FDA, are not our concern

90. Disposition of Comments Report for Stroke Prevention in Atrial Fibrillation (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_disposition-comments.pdf
    August 23, 2013 - Thank you TEP #4 General What appears to be missing are the areas of concern to practitioners for … This is a major concern of patients and physicians for in choosing warfarin vs. the direct thrombin … We agree with the reviewer’s concern and have moderated our discussion of HAS-BLED accordingly. … We agree with the reviewer’s concern and have moderated our discussion of HAS-BLED accordingly. … We have addressed this concern within our future research needs section.

91. Quantitative Synthesis II: Interactive Quiz (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence-quiz.ppt
    May 29, 2025 - Quantitative Synthesis II: Interactive Quiz When To Select Observational Studies Interactive Quiz Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Systematic Reviews Methods Guide www.ahrq.gov When To Select Observational Studies Interactive Quiz When should observational …

92. ENVIRONMENTAL PROTECTION AGENCY (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/manges.pdf
    May 29, 2025 - ENVIRONMENTAL PROTECTION AGENCY INNOVATIONS CONFERENCE -- ENVIRONMENTAL PROTECTION AGENCY SPEAKER: ELLEN MANGES, SENIOR ADVISOR, OFFICE OF SOLID WASTE AND EMERGENCY RESPONSE (OSWER) ENVIRONMENTAL PROTECTION AGENCY (EPA) MANGES: My name is Ellen Manges. I'm a senior advisor. I…

93. Quantitative Synthesis II: Interactive Quiz (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence-quiz.ppt
    May 29, 2025 - Quantitative Synthesis II: Interactive Quiz When To Select Observational Studies Interactive Quiz Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Systematic Reviews Methods Guide www.ahrq.gov When To Select Observational Studies Interactive Quiz When should observational …

94. Disposition of Comments for CER 147 Menopausal Symptoms: Comparative Effectiveness of Therapies (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_disposition-comments.pdf
    March 05, 2015 - Disposition of Comments for CER 147 Menopausal Symptoms: Comparative Effectiveness of Therapies Comparative Effectiveness Review Disposition of Comments Report Research Review Title: Menopausal Symptoms: Comparative Effectiveness Review of Therapies Draft review available for public comment from Novemb…

95. Quantitative Synthesis: Chapter 5. Network Meta-Analysis (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-5.pdf
    February 01, 2018 - . ► These models preserve randomization and alleviate concern about between-arm differences.

96. AHRQ Evidence-based Practice Center (EPC) Program (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-march-2023-grand-rounds-slides.pdf
    January 01, 2023 - by patient characteristics (e.g., age, gender, race/ethnicity, type of clinical condition or health concern … weaknesses (described previously) • Directness (populations, interventions, outcomes of interest) • Not a concern

97. Disposition of Comments Report for Strategies To Reduce Cesarean Birth in Low-Risk Women (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_disposition-comments.pdf
    January 01, 2010 - With regard to the specific concern about hyaluronidase, we note that the vehicles in the formulation … Peer Reviewer #2 Methods Of some concern is the length of publication dates included in the study … With rates much lower than the current US rates of concern, how are we to interpret a lack of effect … Precisely this concern is why there is no aggregate meta- estimate for effects. … Peer Reviewer #2 General Comments There is wide-spread concern about the rising C/S rate of births

98. Epilepsy-Medicine Surveillance (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
    August 01, 2012 - Epilepsy Community Has Major Concern Over Release of Anticonvulsant Drug Comparison Report. … http://www.epilepsyfoundation.org/news/Ep ilepsy-Community-Has-Major-Concern- Over-Release-of-Anticonvulsant-Drug … http://www.epilepsyfoundation.org/news/Epilepsy-Community-Has-Major-Concern-Over-Release-of-Anticonvulsant-Drug-Comparison-Report.cfm … http://www.epilepsyfoundation.org/news/Epilepsy-Community-Has-Major-Concern-Over-Release-of-Anticonvulsant-Drug-Comparison-Report.cfm … http://www.epilepsyfoundation.org/news/Epilepsy-Community-Has-Major-Concern-Over-Release-of-Anticonvulsant-Drug-Comparison-Report.cfm

99. Epilepsy-Medicine Surveillance (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
    August 01, 2012 - Epilepsy Community Has Major Concern Over Release of Anticonvulsant Drug Comparison Report. … http://www.epilepsyfoundation.org/news/Ep ilepsy-Community-Has-Major-Concern- Over-Release-of-Anticonvulsant-Drug … http://www.epilepsyfoundation.org/news/Epilepsy-Community-Has-Major-Concern-Over-Release-of-Anticonvulsant-Drug-Comparison-Report.cfm … http://www.epilepsyfoundation.org/news/Epilepsy-Community-Has-Major-Concern-Over-Release-of-Anticonvulsant-Drug-Comparison-Report.cfm … http://www.epilepsyfoundation.org/news/Epilepsy-Community-Has-Major-Concern-Over-Release-of-Anticonvulsant-Drug-Comparison-Report.cfm

100. Disposition of Comments_Blood-Based Tests for Multiple Cancer Screening: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-disposition-comments.pdf
     May 14, 2025 - appreciated the clear discussion of the policy context, which is very important, and is a cause for concern … This is a clinical concern with follow-up recommendations. … Based on speaking with Key Informants and Technical Expert Panel members, concern was expressed about … We do acknowledge there is a legitimate concern for bias in many studies, including studies sponsored … These comments capture our ongoing concern with AHRQ’s use of mortality as a primary endpoint and the