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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-disposition.pdf
    June 22, 2017 - We agree with the concern about biases that determine what interventions get studied and which studies … get reported and have added this concern to the discussion section. … However, regarding the broader concern of a bias against aspirin, the revised report has more explicit … Zarski, JD) Methods First, an area of significant concern with respect to the literature review is … Zarski, JD) Methods A second concern regards the balance between efficacy and safety in selecting
  2. effectivehealthcare.ahrq.gov/sites/default/files/c-difficile-update_disposition-comments.pdf
    March 29, 2016 - Even if not included in final analysis do not see in excluded list either, thus this raises concern … While the report notes decreased concern about the emergence of vancomycin-resistant enterococci during … We have added language to reflect this concern Public Reviewer NASPGHAN Results The report states … Areas of continued question/concern are highlighted and areas where there is more consensus at this … TEP Reviewer #2 Clarity/ Usability My concern relates to how the results are delivered.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-222-health-equity-preventive-services-comments.pdf
    December 03, 2019 - Disposition of Comments for CER 222: Achieving Health Equity in Preventive Services Comparative Effectiveness Review Disposition of Comments Report Title: Achieving Health Equity in Preventive Services Draft report available for public comment from June 19, 2019 to August 17, 2019. Citation: Nelson HD, Cantor A…
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-205-predictors-trauma-care-disposition-comments.pdf
    April 01, 2018 - & Affiliation Section Comment Response TEP Reviewer #1 General Comments My only general concern … existing literature It is limited primarily by the quality of the existing evidence My general concern … TEP Reviewer #1 Discussion/ Conclusion in light of my comment under general concern may want to
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
    May 01, 2009 - drug use in the absence of evidence regarding efficacy, it made no attempt to define the level of concern … The cost, market entry, and drug promotion factors were combined to indicate a heightened concern about … Off-label use of the atypical antipsychotics has long been a source of concern. … Effective Health Care Research Report Number 12 9 A related concern is that there is a pressing … For example, Black Box warnings may not always reflect an equal magnitude of concern about drug safety
  6. S29 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s29.pdf
    October 01, 2007 - Several expressed concern about making formulary changes as part of the study. … Outcome measures Concern that the outcome measures be meaningful, relevant, appropriate, and sufficient
  7. Slide 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/johnson_-ahrq-mcda-presentation.pdf
    August 27, 2012 - benefits and harms and making informed decisions requires identifying relevant endpoints  Increased concern
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-disposition-comments_0.pdf
    March 03, 2025 - Disposition of Comments_Systematic Review: The Relationship of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, and Body Composition Systematic Review Disposition of Comments Report Title: Association of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabete…
  9. S5 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s5.pdf
    October 01, 2007 - Of particular concern, because of the new Medicare Part D program, are health conditions affecting the … safety or developing estimates of population use of pharmaceuticals.22 Finally, an issue of special concern
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2023-update-executive-summ.pdf
    January 01, 2023 - Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2023 Update of the Evidence Base for the PTSD Trials Standardized Data Repository Systematic Review Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2023 Update of the Evidence Base for the PTSD …
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability-quiz.ppt
    May 29, 2025 - Assessing Applicability: Interactive Case Study Quiz Assessing Applicability Interactive Quiz Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Systematic Reviews Methods Guide www.ahrq.gov Assessing Applicability Interactive Quiz Why might trials with run-in periods and …
  12. effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability-quiz.ppt
    May 29, 2025 - Assessing Applicability: Interactive Case Study Quiz Assessing Applicability Interactive Quiz Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Systematic Reviews Methods Guide www.ahrq.gov Assessing Applicability Interactive Quiz Why might trials with run-in periods and …
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-final-report-update-2024-executive-summ.pdf
    January 01, 2024 - Executive Summary_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2024 Update of the Evidence Base for the PTSD Trials Standardized Data Repository Systematic Review Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2024 Update of the Evidence …
  14. effectivehealthcare.ahrq.gov/sites/default/files/cer-226-labor-dystocia-comments.pdf
    May 14, 2020 - research sections; taken as a whole, these portions of the document succinctly and effectively frame this concern … Given changes in many aspects of practice (particularly threshold for C/S), there was concern that … Given changes in many aspects of practice (particularly threshold for C/S), there was concern that … “prolapsed cord” included in these studies and if so, I would report that since that is a clinical concern … Given changes in many aspects of practice (particularly threshold for C/S), there was concern that
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
    May 01, 2015 - Self-esteem or psychological issues may also be a concern for affected older patients.
  16. effectivehealthcare.ahrq.gov/sites/default/files/study-size-planning-chapter-9.pptx
    January 01, 2013 - /www.ncbi.nlm.nih.gov/pubmed/19808754 Confounding bias, measurement error, and other biases should concern … Confounding bias, measurement error, and other biases should concern investigators more than the expected
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_disposition-comments.pdf
    January 07, 2013 - 10 Commentator & Affiliation Section Comment Response TEP #1 General There is an additional concern … 2013 23 Commentator & Affiliation Section Comment Response Public Reviewer #4 General My main concern … Please see response to similar concern from other reviewers in terms of the benefit of a systematic
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-informed-care-executive-summary.pdf
    January 01, 2025 - Given our concern for locating all relevant literature, we were generous in our screening process.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/vitamin-d-calcium_disposition-comments.pdf
    September 15, 2014 - The concern stated above about the need to include osteomalacia as a bone health outcome for the questions … Regarding the evidence on the important concern of vitamin D deficiency and adult osteomalacia, we … brief mention of compliance and provided several references, including Bolland, which support the concern … Of course, one concern is the absence of data from non-published studies. … I response to the concern that the reader is left to draw his/her own conclusions or at least to decide
  20. effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-32-pharm-non-pharm-ptsd.pdf
    May 14, 2019 - Thank you, we can appreciate this concern and agree that there are other elements that could be reported … We appreciate your concern regarding this study. … We can appreciate the concern over categorization of herbs and supplements as complementary and not … If based in Excel, this is of concern. … We certainly appreciate this reviewers concern and will take it into consideration when preparing the

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