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181. Rapid-Reviews-End-User White-Paper (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-reviews-end-user_white-paper.pdf
     April 01, 2016 - efficiencies, what are they willing to accept), and risks (in terms of the answer being ‘wrong’; level of concern … Without a close and ongoing relationship there is a concern that the actual report becomes distant … less perceived risk of using a rapid product (e.g., in terms of the answer being ‘wrong’ or level of concern … discussion, to challenge the status quo, or to get a sense of the literature when there is a pressing concern

182. Comparative Effectiveness Review Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/bundled-payments-quality-effects_disposition-comments.pdf
     August 24, 2012 - discussion section where “small and/or convenience samples of providers” is cited as a main methodological concern … A primary concern was that the Health Care Financing Administration (HCFA), predecessor to the Center … spending and quality” heading in the “Recommendations for Further Research” subsection to address this concern … Section Comment Response Peer Reviewer #13 General Aside from the above comment and the general concern

183. Treatment Strategies for Women With Coronary Artery Disease: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment-future_research.pdf
     February 01, 2013 - three populations and corresponds to KQs 1b, 2b, and 3b; the second, third, 8 and fourth gaps concern

184. Disposition of Comments Report for Breathing Exercises and/or Retraining Techniques in the Treatment of Asthma: Comparative Effectiveness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-treatment_disposition-comments.pdf
     September 10, 2012 - to express his/her personal frustration and discontent with his/her personal experience of care and concern … Reviewer 2 Methods One concern I have about the exclusion criteria is that given that many of these … although lengthy) was organized and the conclusions, the points of discussion and the areas of possible concern

185. GRADING THE STRENGTH OF A BODY OF EVIDENCE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-strength_methods.pdf
     July 01, 2009 - We briefly explore the rationale for grading strength of evidence, define the domains of concern for … The presence of inconsistency is the chief concern for grading strength of evidence in this domain, … Two types of directness, which can coexist, may be of concern: Evidence is indirect if: • It uses

186. renal-update-2015-150115 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-update_research-protocol.pdf
     January 15, 2015 - approved for biliary ducts, which are not indicated for use in any part of the vasculature,3 and there is concern … Because of a concern that current studies underrepresent patients with acute decompensation due to atherosclerotic

187. Disposition of Comments for Technical Brief 22 Environmental Cleaning for the Prevention of Healthcare-Associated Infections (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/healthcare-infections_disposition-comments.pdf
     August 10, 2015 - Reviewer 5 Findings hydrogen peroxide systems: discuss airway and mucous membrane irritation as a safety concern … A safety concern with improper use is airway and mucous membrane irritation.” … We hope this addresses your concern.

188. Managing Gout: A Review of the Research for Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_consumer.pdf
     January 01, 2017 - � Which possible side effects concern you?

189. Having a breast biopsy. A review of the research for women and thier families (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_consumer.pdf
     May 01, 2016 - But, if the results of the followup tests are of concern, your doctor will recommend a biopsy. 2 3

190. Disposition of Comments_Technical Brief No. 48_Use of Life Cycle Assessment in the Healthcare Industry: Environmental Impacts and Emissions Associated With Products, Processes and Waste (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/lifecycle-assessment-disposition-comments.pdf
     November 20, 2024 - Peer reviewer #1 General My first major concern is that the title and scope of the work do not match … 5 Commentator and Affiliation Section Comment Response Peer reviewer #2 General My largest concern … Commentator and Affiliation Section Comment Response Peer reviewer #2 Introduction I appreciate the concern

191. Comparing Talk Therapy and Other Depression Treatments With Antidepressant Medicines (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_consumer.pdf
     September 01, 2016 - �Which possible side effects from treatment concern you?

192. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/devdelays_adhd_autism_hi_impact.pdf
     January 01, 2012 - However, they expressed concern about the high cost (3 tesla MRI is required), limited availability …  Key Expert Comments: Experts commenting on this intervention expressed concern about the underlying … However, they expressed concern about the high cost, limited availability (i.e., limited to regional … Concern about potential adverse effects, such as oxygen poisoning, barotrauma, and blurred vision

193. Disposition of comments_Comparative Effectiveness Review No. 242: Radiation Therapy for Brain Metastases (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-disposition-comments.pdf
     June 09, 2021 - radiation sensitizers are rarely utilized, and the endpoint of nausea is not commonly one of clinical concern

194. Disposition of Comments CER 214 Stroke Prevention in Patients With Atrial Fibrillation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
     October 30, 2019 - Peer Reviewer #2 General For Key Questions 1 and 2, my main concern about clinical relevance is the … The 2 areas of concern are: (1) the interpretation and discussion of the CHADS2 versus CHA2DS2- VASc … This is an issue of huge concern to clinicians who are caring for frail elderly patients. … We agree this is of concern and that more data are needed on this issue. … Thank you – we have responded to this concern in the general comments section 63.

195. Menopause Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
     March 01, 2015 - 1 Menopausal Symptoms: Comparative Effectiveness of Therapies Executive Summary Background Menopause is defined as the permanent cessation of menstruation and ovulation due to ovarian failure. “Spontaneous” menopause occurs after 12 months of amenorrhea as ovarian hormone secretion diminishes, on average aroun…

196. Single-arm studies in comparative effectiveness reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/single-group-studies_white-paper.pdf
     January 01, 2013 - Single-arm studies in comparative effectiveness reviews Research White Paper Role of Single Group Studies in Agency for Healthcare Research and Quality Comparative Effectiveness Reviews …

197. Living Systematic Reviews: Practical Considerations for the Agency for Healthcare Research and Quality Evidence-based Practice Center Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/practical-considerations.pdf
     March 01, 2022 - The third area of concern was the need to standardize how new evidence is reflected in frequent publications … that managing workload consistency and accuracy across time and managing “burnout” was an issue of concern

198. Disposition of Comments_CER 231 Care Interventions for People Living With Dementia and Their Caregivers (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-231-dementia-care-interventions-disposition-comments.pdf
     July 31, 2020 - The paragraph now reads: “ Another concern is how informal caregivers are perceived, and the way in … I hope the report generates serious concern and new efforts to generate the tools we need to support … Commenter #4 American Psychiatric Association (See Appendix X for full letter) General Our primary concern … variety of reasons that nondrug interventions might be recommended by some as first line, such as concern … about the risk of negative side effects of pharmacological interventions like antipsychotics or concern

199. Disposition of Comments Report for Treatments for Ankyloglossia and Ankyloglossia With Concomitant Lip-Tie (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_disposition-comments.pdf
     May 04, 2015 - Section Comment Response TEP reviewer #7 Methods Regarding inclusion/exclusion criteria, I have a concern

200. Intravascular Diagnostic Procedures and Imaging Techniques Versus Angiography Alone in Coronary Stenting: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting-future_research.pdf
     January 01, 2014 - Intravascular Diagnostic Procedures and Imaging Techniques Versus Angiography Alone in Coronary Stenting: Future Research Needs Future Research Needs Paper Number 25 Intravascular Diagnostic Procedures and Imaging Techniques Versus Angiography Alone in Coronary Stenting: Future Research Needs Future Research Nee…