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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_disposition-comments.pdf
    December 11, 2012 - However, several areas of concern exist form both a literature review perspective as well as relevance … noted above failure of the authors to address ascent of the testis following hormonal therapy is a concern … We appreciate the reviewer's concern and agree that follow-up is required in these patients. … Failure to note the controversy regarding possible harm following hormonal treatment is also of concern
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-216-telehealth-disposition-comments.pdf
    April 24, 2019 - I comment to raise my concern related to the omission of the small but emerging evidence on telehealth … I comment to raise my concern related to the omission of the small but emerging evidence on telehealth … Thank you for your comment and for sharing your concern regarding the scope.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-patient-family-engagement.pdf
    October 01, 2023 - This raises concern about the feasibility and sustainability of relying on new health information technology
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_clinician.pdf
    May 01, 2016 - There is concern that core-needle breast biopsies may miss areas of invasive cancer in specimens in
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0715-140408.pdf
    May 29, 2025 - Topic 0590 Strategies to Treat and Manage Infantile Hemangioma NSD FINAL_SJ Strategies to Treat and Manage Infantile Hemangioma Nomination Summary Document …
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-risk-of-bias.pdf
    December 01, 2017 - Assessing the Risk of Bias in Systematic Reviews of Health Care Interventions Assessing the Risk of Bias in Systematic Reviews of Health Care Interventions Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Systematic Reviews Methods Guide www.ahrq.gov Presenter Presentation …
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0477_11-01-2011.pdf
    January 01, 2011 - Effective Health Care Topic Number: 0396 Document Completion Date: 05-10-12 1 Results of Topic Selection Process & Next Steps  Fibromyalgia treatment will go forward for refinement as a systematic review. The scope of this topic, including populations, interventions, comparators, and outcomes…
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_overview.pdf
    June 24, 2014 - CER 5 Renal Artery Stenosis NSD SJ Clean Renal Artery Stenosis Nomination Summary Document Results of Topic Selection Process & Next Steps § The topic, Renal Artery Stenosis,…
  9. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - Some experts expressed concern over the need for patients to self- administer the drug using an injector … However, some experts expressed concern regarding long-term efficacy and the potential for patients … patients would accept this intervention for similar reasons, but mentioned long-term safety as a concern … However, some experts expressed concern regarding long-term safety and efficacy and the potential for … Some experts expressed concern about long-term safety, citing the history of discontinued antiobesity
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
    June 16, 2010 - 1,000,000 for HIV.26 Emerging infections, such as the West Nile virus epidemic in 2002 in the US are of concern … www.effectivehealthcare.ahrq.gov Published Online: June 16, 2010 9 General Comments EPC Response Overall, there is concern … Given the evidence under consideration, our concern is that prespecificiation could unnecessarily restrict
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
    September 01, 2011 - This concern has been addressed under “Remaining Issues.” … This concern has been addressed under “Remaining Issues.” … Peer Reviewer #3 Methods My main concern is the limited literature search. … This concern should be raised for all of them or none.
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-strength-evidence.ppt
    June 01, 2012 - diagnostic test shows directness when there is a clear link between the test and the health outcome of concern … When there are no studies that directly link the test to the clinical outcomes of concern, then diagnostic … also considers how the population in studies of diagnostic tests may differ from the population of concern … 6) The first step in evidence grading considers which accuracy outcomes for the diagnostic test of concern … The diagnostic test of concern identifies norovirus infection in a health care setting.
  13. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-strength-evidence.ppt
    June 01, 2012 - diagnostic test shows directness when there is a clear link between the test and the health outcome of concern … When there are no studies that directly link the test to the clinical outcomes of concern, then diagnostic … also considers how the population in studies of diagnostic tests may differ from the population of concern … 6) The first step in evidence grading considers which accuracy outcomes for the diagnostic test of concern … The diagnostic test of concern identifies norovirus infection in a health care setting.
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/standardized-library-depression-white-paper.pdf
    May 01, 2020 - Research White Paper: Standardized Library of Depression Outcome Measures Research White Paper Standardized Library of Depression Outcome Measures Research White Paper Standardized Library of Depression Outcome Measures Prepared for: Agency for Healthcare Research and Qual…
  15. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/standardized-library-depression-white-paper.pdf
    May 01, 2020 - Research White Paper: Standardized Library of Depression Outcome Measures Research White Paper Standardized Library of Depression Outcome Measures Research White Paper Standardized Library of Depression Outcome Measures Prepared for: Agency for Healthcare Research and Qual…
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-topic-refinement.pdf
    November 01, 2022 - Public commenters expressed concern that this requirement would require two trials, which was not … Within the comments related to the revised requirements as a set, a common concern was that increasing … Some commenters also expressed concern about a lack of transparency regarding the identities or interests … Finally, a few comments expressed concern that the literature review to inform the revision of requirements
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-dispositIon-comments-2022.pdf
    January 01, 2022 - A minor concern: Did the authors also review Clinical Trials to see if there are other studies that
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_disposition-comments.pdf
    September 10, 2014 - There is a discussion of “harms” and concern regarding incomplete reporting of harms. … assessment of the strength of evidence regarding comparisons among biopsy methods to address this concern … tension occurring between atypical ductal hyperplasia and ductal carcinoma in situ – There is less concern … Again, the lack of attention to this important issue is a concern. Thank you for this comment. … I have some concern about the levels of bias and strength of conclusions related to study design.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
    July 01, 2024 - Clinicians may choose to tailor treatment based on specific outcomes of concern, intervention side
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/epc-making-sure-evidence-understood.pdf
    July 01, 2020 - Which aspects of an illness are of most concern?

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