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101. Disposition of Comments for Interventions for Adolescents and Young Adults With Autism Spectrum Disorders (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_disposition-comments.pdf
     August 27, 2012 - TEP #1 Discussion/ Conclusion My concern with the statement about outcome measures is that although … little or no reviewable data re treatment, but would help to acknowledge that these are areas of concern … Looking at the table (page 324 of 385 reveals concern with measurement of adherence but that should … not be a concern if the comparator is placebo and outcomes are coded blindly in a double-blind study … Peer reviewer #5 Results Nonetheless, this did not leave me with concern that other studies were inadequately

102. Disposition of Comments_Comparative Effectiveness Review No. 267: ADHD Diagnosis and Treatment in Children and Adolescents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-267-adhd-disposition-comments.pdf
     March 25, 2024 - The biggest concern is with neurofeedback. … Chintapalli, The SAI Institute Of Educare and Society For Assistance International Conclusion My only concern … adults. that, "Adding to their Psychological For example, last year there was a case in Virginia in concern

103. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pain-chronic_disposition-comments.pdf
     September 01, 2011 - Peer Reviewer #1 Background One concern that I have is that they compare the US and Europe. … the fact that in many cases this paper addresses chronic non- cancer pain there needs to be special concern … population that is frequently adversely affected by inappropriate prescribing of analgesia of particular concern … Similarly, the concern about declining access to MPPs would be much more compelling if data were presented

104. The Use of Conjoint Analysis to Elicit Patient Preferences in Selecting Treatment Endpoints (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/mcda-johnson.pdf
     August 27, 2012 - benefits and harms and making informed decisions requires identifying relevant endpoints  Increased concern

105. Disposition of Comments Report for Whole-Body Vibration Therapy for Osteoporosis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-vibration-therapy_disposition-comments.pdf
     November 15, 2011 - decided a priori to exclude patients with primary diagnoses other than osteoporosis because there was concern … We have noted this safety concern in our description.

106. Disposition of Comments_Systematic Review: Implementing Recommended Mental Health and Substance Use Screening and Counseling Interventions in Primary Care Settings for in Children and Adolescents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/behavioral-health-screening-disposition-comments.pdf
     April 09, 2025 - There is some concern that this report may under-emphasize the importance of screening because of its

107. DEcIDE DRN Report 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-proof_research.pdf
     June 01, 2010 - The local policy reviews identified several areas of concern for the health plans’ data privacy and … Effective Health Care Program Research Report Number 26 6 Partners indicated concern with data

108. DEcIDE 33: Summary Variables in Observational Resesarch: Propensity Scores and Disease Risk Scores (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
     May 01, 2012 - A greater concern is prognostic variables that are not measured. … An intriguing approach to using the propensity score when there is concern that some important variables … A theoretical concern in the use of the propensity score as a term in a model is that the removal of … Although a theoretical concern, the magnitude of residual confounding from an incorrectly specified … In the NSAID example, this concept might be expressed as a concern that patients with a high underlying

109. Disposition of Comments for CER 202 Effectiveness and Safety of Bronchial Thermoplasty in the Management of Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-202-thermoplasty-comments.pdf
     December 14, 2017 - noted that the AIR trial found a significant reduction in mild exacerbations, but also noted our concern … Our concern was that the unblinded nature of the interventions lowered our confidence for attributing … As such, the ‘concern’ of AHRQ related to BT versus sham comparison may be misplaced.

110. Disposition of Comments for Strategies To Prevent Weight Gain Among Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-gain-prevention_disposition-comments.pdf
     March 25, 2013 - We appreciate the concern for consistency throughout the report. … Agree with Reviewer that confounding is a concern, but the Nurses Health Study/Health Professionals … This is a major concern because producing periodic weight losses, even if there is some weight regain … Peer Reviewer 2 General The other major concern with this review is with the selection of topics. … This is of particular concern because it causes the exclusion of the best known weight gain prevention

111. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/vaccine-safety_research-protocol.pdf
     September 18, 2012 - Perhaps the most highly publicized safety concern of the last 2 decades has been the link between autism … for measles, mumps, and rubella plummeted in the United Kingdom leading to measles outbreaks15 and concern

112. Module II: Stakeholders and Stakeholder Engagement (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/module-ii-stakeholders-and-stakeholder-engagement.pdf
     June 01, 2011 - community organizations identifies the reintegration of drug users after incarceration as a community concern … community organizations identifies the reintegration of drug users after incarceration as a community concern

113. Protocol: Imaging for Pretreatment Staging of Small Cell Lung Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-staging_research-protocol.pdf
     December 08, 2014 - One potential concern about MDCT is patient exposure to ionizing radiation. … Given the poor prognosis for SCLC when it is typically diagnosed, however, this concern is relatively … Again, one potential concern about MDCT is patient exposure to ionizing radiation. … Given the poor prognosis for SCLC when it is typically diagnosed, however, this concern is relatively … The commenter expressed concern that comparative effectiveness evaluations would not recognize the complimentary

114. The Facilitation Primer: Strategies, Tools & Considerations to Get You Started (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_research-2012.pdf
     January 01, 2012 - The Facilitation Primer: Strategies, Tools & Considerations to Get You Started The Facilitation Primer Strategies, Tools & Considerations to Get You Started The Effective Health Care Program Revised January 2012 This guide was created by the Scientific Resource Center at the Oregon Eviden…

115. Disposition of Comments: CER 228, Nonopioid Pharmacologic Treatments for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-228-nonopioid-pharm-chronic-pain-comments.pdf
     April 16, 2020 - Disposition of Comments: CER 228, Nonopioid Pharmacologic Treatments for Chronic Pain Comparative Effectiveness Review Disposition of Comments Report Research Review Title: Nonopioid Pharmacologic Treatments for Chronic Pain Draft report available for public comment from October 15, 2019, to Novem…

116. Executive Summary_Systematic Review_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2022 Update of the PTSD-Repository Evidence Base (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-executive-summ.pdf
     January 01, 2022 - Executive Summary_Systematic Review_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2022 Update of the PTSD-Repository Evidence Base Systematic Review Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2022 Update of the PTSD-Repository Evidenc…

117. September 2021 Surveillance Report 1: Comparative Effectiveness Review No. 250: Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-other-plant-based-treatments-surveillance-report-1-updated_0.PDF
     December 01, 2021 - September 2021 Surveillance Report 1: Comparative Effectiveness Review No. 250: Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain 1 Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Quarterly Progress Report/Surveillance Report 1: Septe…

118. Peripheral-Artery-Disease-Treatment Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
     January 31, 2013 - symptomatic and asymptomatic, reducing the risk of cardiovascular morbidity and mortality is a primary concern … patients with CLI, preventing leg amputation, restoring mobility, and reducing mortality are of paramount concern … when compared to medical therapy, the longevity of results in the femoropopliteal segment remains a concern

119. GRADING THE STRENGTH OF A BODY OF EVIDENCE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
     November 01, 2013 - We briefly explore the rationale for grading strength of evidence, define domains of concern, and describe … This guidance focuses primarily on steps 5 through 8, which concern developing findings and reporting … reporting bias: inconsistent analyses of single and composite (multiple endpoints combined) outcomes raised concern

120. Comments to Effective Heath Care Program Draft Documents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide-2nd-edition_disposition-comments.pdf
     March 03, 2010 - Source: www.effectivehealthcare.ahrq.gov Published Online: March 3, 2010 Page 12: We share your concern … problem of women not presenting early in pregnancy but it is not clear how a registry addresses that concern … www.effectivehealthcare.ahrq.gov Published Online: March 3, 2010 Page 12, Orphan Drugs section: While we share your concern … The first paragraph on Page 15 addresses this concern.