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41. Data Points #3: Economic burden of diabetic foot ulcers and amputations | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/diabetes-foot-ulcer-amputation-economics/research
    December 01, 2019 - Concern for cost-effectiveness has also spurred interest in trying to better understand the potential

42. Peripheral-Artery-Disease-Treatment Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
    May 01, 2013 - 1 Treatment Strategies for Patients With Peripheral Artery Disease Executive Summary Background Peripheral artery disease (PAD) refers to chronic narrowing or atherosclerosis of the lower extremities1 and represents a spectrum of disease severity from asymptomatic disease to intermittent claudication (IC), to …

43. Community Forum Deliberative Methods Demonstration: Evaluating Effectiveness and Eliciting Public Views on Use of Evidence--Executive Summary (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/deliberative-methods-demonstration-executive-131125.pdf
    November 01, 2013 - • Changes in participants’ empathy and concern for issues affecting the community at large. … public’s core values of individual freedom and personal choice were tempered in varying degrees by concern … • Concern for the welfare of the community at large arose when discussing evidence that unchecked … Concern for the greater good surfaced most clearly when discussing how blocking inappropriate use of … • Many participants expressed concern that the primary motivation in establishing limits was cost

44. PHS 398 (Rev. 9/04), Continuation Page (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/upenn-final-report-2005-certs-ce-supplement.pdf
    January 01, 2005 - Background: Probably the most important concern with using claims data for research is its validity. … abrupt loss of heart function.4 It is considered a major cause of mortality, and a major public health concern

45. PHS 398 (Rev. 9/04), Continuation Page (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/administrative-data-validity_research.pdf
    January 01, 2007 - Background: Probably the most important concern with using claims data for research is its validity. … abrupt loss of heart function.4 It is considered a major cause of mortality, and a major public health concern

46. P A W S, Prescription for Antibiotics or Wait and See: Ear Infections: Are Antibiotics the Right Choice for You? (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/ebc-challenge-2ndplace-paws.pdf
    January 26, 2013 - P A W S, Prescription for Antibiotics or Wait and See: Ear Infections: Are Antibiotics the Right Choice for You? P A W S Prescription for Antibiotics or Wait and See Ear Infections Are Antibiotics the Right Choice for You? Your path to good health begins with visiting your retail health pro…

47. S13 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/s13.pdf
    October 01, 2007 - Another concern is the possibility of effect modification, which occurs when the association between … Indeed, the confounders of concern are usually other drugs or other diseases.

48. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2024 Update of the Evidence Base for the PTSD Trials Standardized Data Repository (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ptsd-5-final-report-update-2024_0.pdf
    January 01, 2024 - Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2024 Update of the Evidence Base for the PTSD Trials Standardized Data Repository Systematic Review Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2024 Update of the Evidence Base for the PTS…

49. For adult female patients, what is the comparative effective of non-surgical and surgical treatment of chronic pelvic pain? | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/for-adult-female-patients-what-is-the-comparative-effective-of-non-surgical-and-surgical-treatment-of-chronic-pelvic-pain
    November 01, 2017 - Also concern involves persistence of chronic pain post-surgery and poassible predictors of poor outcomes

50. Evidence Summary_Comparative Effectiveness Review No. 257: Schedule of Visits and Televisits for Routine Antenatal Care: A Systematic Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-257-antenatal-care-evidence-summary.pdf
    June 01, 2022 - Evidence Summary_Comparative Effectiveness Review No. 257: Schedule of Visits and Televisits for Routine Antenatal Care: A Systematic Review Comparative Effectiveness Review Number 257 Schedule of Visits and Televisits for Routine Antenatal Care: A Systematic Review Evidence Summary Main Points …

51. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2024 Update of the Evidence Base for the PTSD Trials Standardized Data Repository | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/ptsd-pharm-non-pharm-treatment-update/research
    March 01, 2025 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

52. Reliability Testing of the AHRQ EPC Approach to Grading the Strength of Evidence in Comparative Effectiveness Reviews | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/reliability-testing-grading-evidence/research
    November 01, 2017 - Of particular concern is how to deal with (a) outcomes that are evaluated through a combination of RCTs

53. Disposition of Comments for CER 161 Major Depressive Disorder (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/major-depressive-disorder-disposition-160504.pdf
    December 08, 2015 - However, we changed our SOE rating from moderate to low for the SJW analyses to reflect our concern … We appreciate the concern of the reviewer. … Agreed – herb-drug interactions are a concern when considering SJW, which is why we have recommended … But let me introduce my first concern with St. John's Wort. … I won't repeat my concern about the use of "alternative."

54. Should subclinical hypothroidism be treated? | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/should-subclinical-hypothroidism-be-treated
    November 01, 2017 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

55. Disposition of Comments for CER 222: Achieving Health Equity in Preventive Services (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-222-health-equity-preventive-services-comments.pdf
    December 03, 2019 - Disposition of Comments for CER 222: Achieving Health Equity in Preventive Services Comparative Effectiveness Review Disposition of Comments Report Title: Achieving Health Equity in Preventive Services Draft report available for public comment from June 19, 2019 to August 17, 2019. Citation: Nelson HD, Cantor A…

56. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2025 Update of the Evidence Base for the PTSD Trials Standardized Data Repository | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/ptsd-pharm-non-pharm-treatment-2025-update/draft-report
    April 01, 2025 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

57. More information is needed on the long-term effects of antipsychotic therapy in older adults. Please consider new research in the benefits and harms of treating patients with atypical antipsychotics. | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/more-information-is-needed-on-the-long-term-effects-of-antipsychotic-therapy-in-older-adults-please-consider-new-research-in-the-benefits-and-harms-of-treating-patients-with-atypical-antipsychotics
    November 01, 2017 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

58. What is the most effective therapy for a depressed patient who has not responded to an SSRI? | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/what-is-the-most-effective-therapy-for-a-depressed-patient-who-has-not-responded-to-an-ssri
    November 01, 2017 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

59. S29 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/s29.pdf
    October 01, 2007 - Several expressed concern about making formulary changes as part of the study. … Outcome measures Concern that the outcome measures be meaningful, relevant, appropriate, and sufficient

60. Effectiveness of Screening and Treatment of Subclinical Hypothyroidism or Hyperthyroidism (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hypothyroidism-hyperthyroidism-screening-treatment_disposition-comments.pdf
    February 01, 2012 - A potential concern is the exclusion for further consideration patients detected through screening … highlight that this led to no change in health risk Have added language that we hope addresses this concern … We added text to address this concern Source: http://www.effectivehealthcare.ahrq.gov/index.cfm … Changes to text addresses this concern Peer Reviewer #6 Introduction Page 16, line 38-42.