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161. Use of Observational Studies in Systematic Reviews of (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguidenorris_060420101.pdf
     June 01, 2010 - variables recorded on the basis of the results, for inclusion in the study publications.28 The main concern

162. Use of Observational Studies in Systematic Reviews of (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
     June 01, 2010 - variables recorded on the basis of the results, for inclusion in the study publications.28 The main concern

163. Imaging for Pretreatment Staging of Small Cell Lung Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/lung-cancer-staging/research-protocol
     December 01, 2019 - One potential concern about MDCT is patient exposure to ionizing radiation. … Given the poor prognosis for SCLC when it is typically diagnosed, however, this concern is relatively … Again, one potential concern about MDCT is patient exposure to ionizing radiation. … Given the poor prognosis for SCLC when it is typically diagnosed, however, this concern is relatively … The commenter expressed concern that comparative effectiveness evaluations would not recognize the complimentary

164. The Use of Conjoint Analysis to Elicit Patient Preferences in Selecting Treatment Endpoints (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/mcda-johnson.pdf
     August 27, 2012 - benefits and harms and making informed decisions requires identifying relevant endpoints  Increased concern

165. Omega-3 Fatty Acids and Maternal and Child Health: An Updated Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/omega-3-maternity/research
     April 01, 2021 - Risk of bias was a concern with both RCTs and observational studies.

166. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0477_11-01-2011.pdf
     January 01, 2011 - Effective Health Care Topic Number: 0396 Document Completion Date: 05-10-12 1 Results of Topic Selection Process & Next Steps  Fibromyalgia treatment will go forward for refinement as a systematic review. The scope of this topic, including populations, interventions, comparators, and outcomes…

167. CER 5 Renal Artery Stenosis NSD SJ Clean (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_overview.pdf
     June 24, 2014 - CER 5 Renal Artery Stenosis NSD SJ Clean Renal Artery Stenosis Nomination Summary Document Results of Topic Selection Process & Next Steps § The topic, Renal Artery Stenosis,…

168. | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/r
     Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

169. | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/R
     Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

170. Disposition of Comments Report for Strategies To Reduce Cesarean Birth in Low-Risk Women (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_disposition-comments.pdf
     January 01, 2010 - With regard to the specific concern about hyaluronidase, we note that the vehicles in the formulation … Peer Reviewer #2 Methods Of some concern is the length of publication dates included in the study … With rates much lower than the current US rates of concern, how are we to interpret a lack of effect … Precisely this concern is why there is no aggregate meta- estimate for effects. … Peer Reviewer #2 General Comments There is wide-spread concern about the rising C/S rate of births

171. Obesity (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - Some experts expressed concern over the need for patients to self- administer the drug using an injector … However, some experts expressed concern regarding long-term efficacy and the potential for patients … patients would accept this intervention for similar reasons, but mentioned long-term safety to be a concern … Some experts expressed concern about the long-term safety of this intervention, citing the history … trials is similar to medications currently approved by the FDA.”63 But several experts expressed concern

172. Disposition of Comments for Child Exposure to Trauma: Comparative Effectiveness of Interventions Addressing Maltreatment (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/trauma-interventions-maltreatment-child_disposition-comments.pdf
     April 15, 2013 - A concern given the weak and thin evidence reported in this review is that if policy makers or payer … My overall concern is that the methodology used to rule out certain studies may have severely limited … Finally, my only other methodological concern I’d like to mention is that there were only two reviewers

173. Multidisciplinary Postacute Rehabilitation for Moderate to Severe Traumatic Brain Injury in Adults Disposition of Comments (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_disposition-comments.pdf
     October 07, 2012 - explained, the arbitrary selection of 6-months post injury outlined in Topic Refinement remains of concern … This issue was raised during the TEP teleconferences, yet, the review does not appear to address this concern … specific interventions and lack of focus on maintenance of function and reduced burden of care are of concern … Text in Discussion section addresses concern that studies may not be indicative of commonly utilized

174. Dietary Intake of Polyunsaturated Fatty Acids and Plasma Lipid and Cardiovascular Events (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/polyunsaturated-fatty-protocol.pdf
     January 01, 2024 - Dietary Intake of Polyunsaturated Fatty Acids and Plasma Lipid and Cardiovascular Events Evidence-based Practice Center Systematic Review Protocol Project Title: Dietary Intake of Polyunsaturated Fatty Acids and Plasma Lipid and Cardiovascular Events I. Background and Purpose of the Systematic Review…

175. Dietary Saturated Fat Replacement and Plasma Lipid and Cardiovascular Events (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/saturated-fat-replacement-protocol.pdf
     January 01, 2024 - Dietary Saturated Fat Replacement and Plasma Lipid and Cardiovascular Events Evidence-based Practice Center Systematic Review Protocol Project Title: Dietary Saturated Fat Replacement and Plasma Lipid and Cardiovascular Events I. Background and Purpose of the Systematic Review Background The fatt…

176. Vitamin D and Calcium: A Systematic Review of Health Outcomes (Update) | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/vitamin-d-calcium/research
     December 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

177. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - Epilepsy Community Has Major Concern Over Release of Anticonvulsant Drug Comparison Report. … http://www.epilepsyfoundation.org/news/Ep ilepsy-Community-Has-Major-Concern- Over-Release-of-Anticonvulsant-Drug … http://www.epilepsyfoundation.org/news/Epilepsy-Community-Has-Major-Concern-Over-Release-of-Anticonvulsant-Drug-Comparison-Report.cfm … http://www.epilepsyfoundation.org/news/Epilepsy-Community-Has-Major-Concern-Over-Release-of-Anticonvulsant-Drug-Comparison-Report.cfm … http://www.epilepsyfoundation.org/news/Epilepsy-Community-Has-Major-Concern-Over-Release-of-Anticonvulsant-Drug-Comparison-Report.cfm

178. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - Epilepsy Community Has Major Concern Over Release of Anticonvulsant Drug Comparison Report. … http://www.epilepsyfoundation.org/news/Ep ilepsy-Community-Has-Major-Concern- Over-Release-of-Anticonvulsant-Drug … http://www.epilepsyfoundation.org/news/Epilepsy-Community-Has-Major-Concern-Over-Release-of-Anticonvulsant-Drug-Comparison-Report.cfm … http://www.epilepsyfoundation.org/news/Epilepsy-Community-Has-Major-Concern-Over-Release-of-Anticonvulsant-Drug-Comparison-Report.cfm … http://www.epilepsyfoundation.org/news/Epilepsy-Community-Has-Major-Concern-Over-Release-of-Anticonvulsant-Drug-Comparison-Report.cfm

179. Disposition of Comments for Interventions for Adolescents and Young Adults With Autism Spectrum Disorders (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/autism-adolescents_disposition-comments.pdf
     August 27, 2012 - TEP #1 Discussion/ Conclusion My concern with the statement about outcome measures is that although … little or no reviewable data re treatment, but would help to acknowledge that these are areas of concern … Looking at the table (page 324 of 385 reveals concern with measurement of adherence but that should … not be a concern if the comparator is placebo and outcomes are coded blindly in a double-blind study … Peer reviewer #5 Results Nonetheless, this did not leave me with concern that other studies were inadequately

180. Protocol Amendment - Safety of Vaccines 030413 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/vaccines-safety-protocol-130325.pdf
     September 18, 2012 - Perhaps the most highly publicized safety concern of the last 2 decades has been the link between autism … for measles, mumps, and rubella plummeted in the United Kingdom leading to measles outbreaks15 and concern