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  1. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/impaired-visual-acuity-screening-older-adults
    May 24, 2022 - settings or were feasible for primary care (did not require eye specialty training or equipment) and compared … Four fair-quality RCTs 19 , 23 , 34 , 46 , 47 , 61 (in 6 publications; n = 4819) compared vision screening … Three studies (n = 6493) evaluated screening visual acuity tests compared with a complete ophthalmologist … Three new good-quality trials (n = 2738; reported in 5 publications) compared aflibercept vs the older … No trial compared brolucizumab-dbll vs an older VEGF inhibitor. Key Question 7.
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/mTPBWPMDqfuWvodfd5R5Ms
    November 01, 2012 - with 1-time screening or compared the yield of different strategies for repeated screening (such as … Final (40- month) results (14) found that compared with Western blot (the reference standard), sensitivity … No study compared psychological or other harms as- sociated with rapid versus standard tests or adverse … Triple antiretroviral compared with zidovudine and single-dose nevirapine prophylaxis during pregnancy … A randomized, double-blind, placebo-controlled trial of combined nevirapine and zidovudine compared with
  3. www.uspreventiveservicestaskforce.org/uspstf/document/screening-for-hiv-in-pregnant-women-evidence-summary/human-immunodeficiency-virus-hiv-infection-screening-2013
    November 15, 2012 - No randomized trial or observational study evaluated the yield of repeated prenatal HIV screening compared … with 1-time screening or compared the yield of different strategies for repeated screening (such as … Final (40-month) results 14 found that compared with Western blot (the reference standard), sensitivity … No study compared psychological or other harms associated with rapid versus standard tests or adverse … Triple antiretroviral compared with zidovudine and single-dose nevirapine prophylaxis during pregnancy
  4. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/hepatitis-b-virus-infection-screening
    December 15, 2020 - 19 Twelve good- or fair-quality trials (N = 4127; n = 44-715; duration, 3.7-22 months) in adults compared … , both first-line regimens achieved significantly higher virologic suppression or ALT normalization compared … Nine trials (N = 3408) compared harms of first-line antiviral regimens with harms of alternate regimens … Pegylated interferon was associated with an increased risk of any adverse event compared with lamivudine … entecavir with lamivudine or compared TDF with adefovir.
  5. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer-medications-for-risk-reduction
    September 03, 2019 - Tamoxifen and raloxifene were associated with increased thromboembolic events compared with placebo; … Tamoxifen was associated with higher risk of endometrial cancer and cataracts compared with placebo. … No studies specifically compared shorter vs longer regimens of medication use or initiation based on … Risks for thromboembolic events and endometrial cancer with tamoxifen were higher for older compared … Furthermore, no trials directly compared the effects of timing and duration of medication use.
  6. www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-screening-january-2016
    January 11, 2016 - recall rates (i.e., follow-up for additional imaging or testing) and increase cancer detection rates compared … No clinical trials compared annual mammography with a longer interval in women of any age. … Data from the BCSC indicate that, compared with women with average breast density, women aged 40 to 49 … Four case-series included in the systematic evidence review compared breast cancer treatments in women … or compared 2 screening cohorts of women (conventional digital mammography alone vs. combined with DBT
  7. www.uspreventiveservicestaskforce.org/uspstf/recommendation/depression-in-children-and-adolescents-screening-2009
    March 15, 2009 - Also needed are studies to examine collaborative care management approaches compared with usual clinical … disorders have increased health care costs (including general medical care and mental health care) compared … with placebo, 10 different group or individually delivered psychotherapies compared with control conditions … and receiving weekly clinical monitoring. 2 Nearly 3 of 4 patients responded to combined therapy, compared … aged 5 to 29 years, the conversion rate in patients using antidepressants was 7.7 percent per year, compared
  8. www.uspreventiveservicestaskforce.org/home/getfilebytoken/eSLqaKpvzhYRbQVeumNgSQ
    January 19, 2021 - advice from clinicians (RR, 1.76 [95% CI, 1.58-1.96]) were all associated with increased quit rates compared … the effectiveness of electronic cigarettes on smoking cessation at 6 to 12 months among smokers when compared … were associated with greater smoking cessation during late pregnancy (RR, 1.35 [95% CI, 1.23-1.48]), compared … For instance, in an examination of counseling interven- tions compared with usual care, the average RR … E-cigarettes compared with nicotine replacement therapy within the UK Stop Smoking Services: the TEC
  9. www.uspreventiveservicestaskforce.org/uspstf/recommendation/asymptomatic-bacteriuria-adults-screening-1996
    January 01, 1996 - esterase or nitrite testing in pregnant women is not recommended because of poor test characteristics compared … been reported in asymptomatic diabetic women, although several studies have found no increase when compared … When compared with culture (at least 100,000 organisms/mL), it has a sensitivity of 72-97% and a specificity … Compared to suprapubic aspiration, positive results on bag specimens indicate true bacteriuria in only … Inability of the Chemstrip LN compared with quantitative urine culture to predict significant bacteriuria
  10. www.uspreventiveservicestaskforce.org/home/getfilebytoken/_9KLmyQyMnoE3agQJsgNE-
    November 01, 2011 - These trials compared relative detec- tion of CIN3� and CIN2� and relative positive predic- tive value … For HPV screening fol- lowed by cytology triage compared with cytology alone, we found 1 Finnish RCT … Pooled results suggested decreased cumulative cases of in- vasive cancer after HPV screening, compared … Primary HPV Screening Followed by Cytology Triage Compared With Cytology Alone A large, fair-quality … After a single screening round, Hybrid Capture 2 testing with cytology triage compared with cytology
  11. www.uspreventiveservicestaskforce.org/home/getfilebytoken/NZ_RQWxMMR8Vym-yJuqru-
    May 23, 2019 - No study has compared a screened with a comparable un- screened sample to determine the difference in … Ten RCTs and three meta-analyses have compared clinical outcomes among diabetic persons treated with … Hypertensive per- sons taking calcium antagonists compared with those tak- ing other drugs may have a … Some evidence suggests that, compared with most other antihypertensive drugs, ACE inhibitors or ARBs … Nonetheless, the meta-analyses compared results across trials.
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Yc24U4wMLXGoqE5NjwRVA6
    April 17, 2018 - Compared with placebo, supplementation with vitamin D decreased total fracture incidence (1 RCT [n = … Four RCTs reported the effect of vitamin D alone compared with placebo15-18 or control group with no … For calcium alone com- pared with placebo, only 1 study was eligible, and it compared 600-mg or 1200- … placebo, 1 RCT reported incident nonskin cancer in 17 women (3.8%) who took calcium compared with 20 … e Reflects effect estimates of the 600-mg or 1200-mg calcium dose compared with placebo.
  13. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hypertension-in-adults-screening
    October 04, 2018 - office-based blood pressure measurement during a single encounter as initial screening for high blood pressure compared … confirmatory blood pressure measurement in adults who initially screen positive for high blood pressure compared … standard sphygmomanometer) with identical screening protocols; validation and accuracy studies of devices compared
  14. www.uspreventiveservicestaskforce.org/home/getfilebytoken/2Wc3FRHpVDPX2jT_WzjEXX
    July 31, 2020 - that screening every 3 y does not provide a favorable (ie, efficient) balance of benefits and harms compared … When performed alone, direct visualization tests allow for a much longer time between screen- ings compared … Pooled results from 4 RCTs (n = 458 002) on flexible sigmoidoscopy compared with no screening show a … d Compared with other options for stool-based screening, these strategies do not provide an efficient … d Compared with other options for stool-based screening, these strategies do not provide an efficient
  15. www.uspreventiveservicestaskforce.org/uspstf/recommendation/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
    August 20, 2024 - odds ratio [OR], 0.75 [95% CI, 0.61-0.91]) and preterm birth (adjusted OR, 0.59 [95% CI, 0.47-0.72]) compared … and preeclampsia (adjusted OR, 1.44 [95% CI, 1.16-1.76] and 1.45 [95% CI, 1.26-1.67], respectively) compared … ferritin values) and decreased risk of maternal iron deficiency anemia, iron deficiency, and anemia compared … with placebo; most studies found higher hemoglobin and serum ferritin values at term compared with placebo … a separate trial (n = 111), nonadherence to iron therapy was lower in adults taking supplementation compared
  16. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/obstructive-sleep-apnea-in-adults-screening
    November 15, 2022 - In 7 trials, 17% to 74% of participants reported oral mucosal, dental, or jaw symptoms, compared with … In 4 trials, 5% to 33% of participants reported oral dryness, compared with 0% to 3% in control groups … , and in 3 trials, 23% to 68% of participants reported excessive salivation, compared with 0% to 3% in … No trials were identified that directly compared benefits in screened vs unscreened populations. … No trials were identified that directly compared harms in screened vs unscreened populations.
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/e6_WqcwDGhgT6bQfmk3Hqj
    February 02, 2021 - benefit in reducing adverse health outcomes, including stroke, myocardial infarction, or mortality, compared … Pooled analyses found that, compared with patients receiving medical therapy alone, 2.0% fewer patients … randomized to CEA.7,9 Results from comparative effectiveness studies of CEA plus best medical therapy compared … alone (calculated unadjusted HR, 0.20 [95% CI, 0.06-0.65]).7,18 The 2014 review found no studies that compared … Angioplasty in asymptomatic carotid artery stenosis vs. endarterectomy compared to best medical treatment
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/dCH2CMqVyAzf4eyj-ch6H3
    August 09, 2016 - 20% to 40%; 1 trial (n = 214) showed a 2.01% decrease in carotid intima-media thickness with statins, compared … In 1 trial (n = 248), ezetimibe with simvastatin resulted in greater LDL-C reductions compared with simvastatin … 2.01% decrease in CIMT after 104 weeks (absolute difference, −0.010 mm [95% CI, −0.019 to −0.001]), compared … colestipol found a mean LDL-C reduction of 19.5% after 8 weeks (absolute difference, −50.7 mg/dL), compared … LDL-C of 10% (95% CI, −14.1% to −5.9%) at the higher of 2 doses (absolute difference, −24.1 mg/dL), compared
  19. www.uspreventiveservicestaskforce.org/uspstf/recommendation/human-immunodeficiency-virus-hiv-infection-screening
    June 11, 2019 - 2017 HIV Surveillance Report show a significant increase in HIV diagnoses starting at age 15 years (compared … The USPSTF found no evidence on the yield of repeat prenatal screening for HIV compared with 1-time screening … and Treatment The USPSTF found no randomized clinical trials (RCTs) or observational studies that compared … The USPSTF found no studies that evaluated the yield of repeated screening for HIV compared with 1-time … screening or that compared the yield of different strategies for repeat screening (eg, risk-based screening
  20. www.uspreventiveservicestaskforce.org/home/getfilebytoken/r_MgZHrtyHRn7rZoCPS6MT
    February 01, 2011 - for amblyopia or unilateral refractive error were associated with mild improvements in visual acuity compared … No randomized trial evaluated pre- school vision screening compared with no screening. … No randomized trial evaluated outcomes of preschool vision screening compared to no screening. … Well-designed studies are needed to better understand the effects of screening compared with no screen … Preschool vision screening tests administered by nurse screeners compared with lay screeners in the

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