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61. Draft Recommendation: Intimate Partner Violence and Caregiver Abuse of Older or Vulnerable Adults: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/intimate-partner-violence-abuse-older-vulnerable-adults
    October 29, 2024 - violence (32.5%), and adverse health and social consequences associated with experiencing IPV (87%) compared … disability, are more likely to experience violent victimization and maltreatment regardless of age compared … In one study, IPV victimization was lower in the intervention group (7.50 events per person-year) compared … Three studies (n=3,759) compared screening with no screening for IPV and found no benefit when screening … Five trials reported on specific categories of IPV. 1 Generally, compared with studies enrolling pregnant

62. Final Research Plan: Prostate Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/prostate-cancer-screening-adults
    December 21, 2023 - *Active surveillance and watchful waiting are typically compared … calculator or MRI in combination with a positive PSA-based screening test on prostate cancer biopsy rates compared … PSA-based screening test on prostate cancer morbidity and mortality, quality of life, and function compared … ‡Active surveillance and watchful waiting are typically compared to more active treatments in trials.

63. Final Recommendation Statement: Breast Cancer: Medication Use to Reduce Risk | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/breast-cancer-medications-for-risk-reduction
    September 03, 2019 - at some point in their lifetime. 2 African American women are more likely to die of breast cancer compared … Risk-Reducing Medications A systematic review of trials conducted for the USPSTF found that compared … However, the large Study of Tamoxifen and Raloxifene (STAR) trial, which directly compared tamoxifen … with placebo or no treatment. 12 Another study that compared anastrozole with tamoxifen in treating … . 11 , 87 The meta-analysis that evaluated extended use of aromatase inhibitors compared with placebo

64. Recommendation: Breast Cancer: Medication Use to Reduce Risk | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction
    September 03, 2019 - Risk-Reducing Medications A systematic review of trials conducted for the USPSTF found that compared … However, the large Study of Tamoxifen and Raloxifene (STAR) trial, which directly compared tamoxifen … Based on the STAR trial, more harms were reported with tamoxifen compared with raloxifene: 4 more cases … with placebo or no treatment. 12 Another study that compared anastrozole with tamoxifen in treating … . 11 , 87 The meta-analysis that evaluated extended use of aromatase inhibitors compared with placebo

65. JAMA (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/4_pXjq7Egjwb_vjZZT-NGB
    May 01, 2021 - study (n = 2441) evaluated proteinuria screening conducted only for specific clinical indications, compared … with White persons (29.7 compared with 12.7 per 100 000 live births in 2007-2016).7,11,19 In 2017, … The studies compared usual screening with strategies involving home bloodpressuremeasurement(2studies … ,n = 2521),prenatalcaresched- ules with less frequent office visits compared with the usual number (3 … We identified 3 fair-quality RCTs (n = 5203) that compared dif- ferent prenatal visit schedules among

66. Final Evidence Summary: Hepatitis C Virus Infection in Adolescents and Adults: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hepatitis-c-screening
    March 02, 2020 - An SVR after antiviral therapy was associated with improved clinical outcomes compared with no SVR. … No study compared harms of HCV screening vs no screening. … trials (reported in 1 publication) compared a current vs older DAA regimen. 15 The other treatment … Few studies compared DAA interventions with placebo or older interventions (eTable 5 in the Supplement … Research studies of DAA therapy could overestimate SVR rates compared with typical clinical practice.

67. Screening for Latent Tuberculosis Infection in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/oPmYxryXGu2occANaReagc
    August 01, 2022 - isoniazid with pla- cebo, 2 compared rifampin with isoniazid, and 2 compared rifapen- tine plus isoniazid … Four additional RCTs125-128 that compared isoniazid with pla- cebo that did not meet all eligibility … Rifampin Compared With Isoniazid Two RCTs comparing rifampin with isoniazid were included. … Rifapentine Plus Isoniazid Compared With Isoniazid Alone Two RCTs compared rifapentine plus isoniazid … Rifapentine Compared With Isoniazid Two RCTs reported harms for rifapentine plus isoniazid compared with

68. Recommendation: Skin Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/skin-cancer-screening
    April 18, 2023 - Incidence of melanoma is higher among White persons compared with persons of other races and ethnicities … At the 5-year follow-up, melanoma mortality declined 49% in the screening region compared with surrounding … One fair-quality study (N not reported) compared melanoma mortality between Germany and 22 other European … skin cancer screening program found a higher proportion of melanoma deaths in the unscreened group compared … detection. 24 US-based studies also showed higher melanoma mortality risk at all stages among men compared

69. Recommendation: Asymptomatic Carotid Artery Stenosis: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/carotid-artery-stenosis-screening
    February 02, 2021 - Pooled analyses found that, compared with patients receiving medical therapy alone, 2.0% fewer patients … calculated unadjusted HR, 0.20 [95% CI, 0.06-0.65]). 7 , 18 The 2014 review found no studies that compared … CAS with medical therapy. 8 The current review 7 identified 1 trial that compared CAS with best medical … Angioplasty in asymptomatic carotid artery stenosis vs. endarterectomy compared to best medical treatment … benefit in reducing adverse health outcomes, including stroke, myocardial infarction, or mortality, compared

70. Screening for Syphilis: A Brief Update (pdf file)
    www.uspreventiveservicestaskforce.org/USPSTF_Admin/Home/GetFile/1/996/syphilup/pdf
    July 01, 2004 - to TPHA, and 99.4% and 100% compared to the FTA-ABS test. … ELISA showed 100% sensitivity compared to the FTA-ABS test for primary and secondary syphilis, 100% for … This study compared results of clinic RPR and RST tests with standard laboratory RPR and TPHA tests in … A study of the treatment of individuals exposed to a sexual partner with early- stage syphilis compared … Azithromycin compared with penicillin G benzathine for treatment of incubating syphilis.

71. Recommendation: Colorectal Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening
    May 18, 2021 - estimated to provide a reasonable balance of life years gained per estimated follow-up colonoscopy compared … When performed alone, direct visualization tests allow for a much longer time between screenings compared … Pooled results from 4 RCTs (n = 458,002) on flexible sigmoidoscopy compared with no screening show a … See modeling report 12 for more information. d Compared with other options for stool-based screening … See modeling report 12 for more information. d Compared with other options for stool-based screening

72. Screening for Latent Tuberculosis Infection in Adults: US Preventive Services Task Force Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/KdQef_VDT2kmHDX4ddNWmR
    August 01, 2022 - that persons experiencing homelessness have an 11 times higher incidence of tuberculosis dis- ease compared … the benefits on health outcomes of LTBI-screened popu- lations compared with unscreened populations. … More recent comparative effectiveness trials have compared other treatment regimens with isoniazid alone … The IUAT trial reported on harms of treatment of LTBI with isoniazid compared with placebo.32,37 An … Meta-analysis of 3 trials (n = 7339) that compared isoniazid vs rifampin found a higher pooled RR of

73. Recommendation: Latent Tuberculosis Infection in Adults: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/latent-tuberculosis-infection-screening
    May 02, 2023 - the benefits on health outcomes of LTBI-screened populations compared with unscreened populations. … More recent comparative effectiveness trials have compared other treatment regimens with isoniazid alone … Two clinical trials (n = 7149) have compared treatment of LTBI with rifapentine plus isoniazid vs isoniazid … The IUAT trial reported on harms of treatment of LTBI with isoniazid compared with placebo. 32 , 37 … Meta-analysis of 3 trials (n = 7339) that compared isoniazid vs rifampin found a higher pooled RR of

74. Recommendation: Osteoporosis to Prevent Fractures: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/osteoporosis-screening
    January 14, 2025 - in women and 5.7% in men) compared with persons aged 50 to 64 years (13.1% in women and 3.3% in men) … Twenty-one RCTs compared bisphosphonates with placebo. … Five trials compared alendronate with placebo, 2 compared risedronate with placebo, and 3 compared zoledronic … Three studies compared alendronate with placebo, 2 compared risedronate with placebo, and 1 compared … Excess mortality in men compared with women following a hip fracture.

75. Final Evidence Summary: Depression and Suicide Risk in Children and Adolescents: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary27/screening-depression-suicide-risk-children-adolescents
    October 11, 2022 - Differences in suicide-related outcomes and adverse events for pharmacotherapy when compared with placebo … escitalopram with placebo. 31 , 39 One 3-group trial compared fluoxetine, cognitive behavioral therapy … (CBT), and placebo. 34 One trial compared collaborative care with enhanced usual care. 36 Six studies … First, no studies were available that compared screening with no screening. … Dialectical behavior therapy compared with enhanced usual care for adolescents with repeated suicidal

76. Radiation-Induced Breast Cancer and Breast Cancer Death From Mammography Screening (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/BMh7ctXLmgRXhC4CVZGJNH
    April 01, 2015 - cancers and 35 deaths per 100,000 women; 95th percentile, 481 cancers and 63 deaths per 100,000 women) compared … For example, compared to annual screening from ages 40 to 74 years, biennial screening from ages 50

77. Radiation-Induced Breast Cancer and Breast Cancer Death From Mammography Screening (pdf file)
    www.uspreventiveservicestaskforce.org/Home/GetFileByID/1932
    April 01, 2015 - cancers and 35 deaths per 100,000 women; 95th percentile, 481 cancers and 63 deaths per 100,000 women) compared … For example, compared to annual screening from ages 40 to 74 years, biennial screening from ages 50

78. Evidence Summary: Prostate Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/prostate-cancer-screening
    May 08, 2018 - Compared with conservative approaches, active treatments for screen-detected prostate cancer have unclear … Three RCTs (n = 2524) 66-68 and 11 cohort studies (n = 8809) 10 , 11 , 69-78 compared harms among men … treated with radical prostatectomy compared with conservative management, and 6 uncontrolled studies … harms among men treated with radiation therapy compared with conservative management, and 1 uncontrolled … No studies compared HIFU with conservative management; only 1 study had a sample size exceeding 1000

79. Screening for Lung Cancer With Low-Dose Computed Tomography: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/ghbfx9e3A6jQEqVW26y8Jv
    March 09, 2021 - LDCT with chest radiography (LSS and NLST), and 5 trials in Europe compared LDCT with no screen- ing … The NLST found a reduction in all-cause mortality with LDCT screening compared with chest radiography … b NLST and LSS compared screening with LDCT vs screening with chest radiography. … All other trials compared screening with LDCT with no screening. … Three studies (73 404 partici- pants) compared various approaches to nodule classification (Lung-RADS

80. Archived: Evidence Summary: Latent Tuberculosis Infection: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-latent-tuberculosis/latent-tuberculosis-infection-screening-september-2016
    September 06, 2016 - No studies evaluated benefits and harms of screening compared with no screening. … placebo (n = 27,830) 97 ; 1 compared rifampin with isoniazid (n = 847)[95]]; and 1 compared rifapentine … Five RCTs were included. 94-98 One compared isoniazid with placebo (n = 27,830) 97 ; 3 compared rifampin … Three studies provided evidence on harms of rifampin as compared with isoniazid. … placebo and an RR of 3.29 compared with rifampin.