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  1. www.uspreventiveservicestaskforce.org/uspstf/recommendation/latent-tuberculosis-infection-screening-september-2016
    September 06, 2016 - The other 2 treatment trials compared either rifampin with isoniazid and found zero deaths in either … The other trials compared either rifampin 30 , 32 , 33  or rifapentine plus isoniazid 31  with isoniazid … Meta-analysis of 3 trials of rifampin compared with isoniazid found a higher RR for hepatoxicity among … because of gastrointestinal adverse events (RR, 1.33 [95% CI, 1.01 to 1.75]). 29  Compared with rifampin … Compared with placebo, treatment with isoniazid had an RR of medication discontinuation of 1.50 (95%
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/sZN5HHS8w5Sar6bBPabsaB
    June 01, 2008 - A second study compared ve- rapamil with either a �-blocker or a thiazide diuretic and found no evidence … It showed that persons with dia- betes had lower cardiovascular mortality with losartan compared with … We identified 1 meta-analysis of antihypertensive trials that compared outcomes between persons with … All of the studies of angiotensin-converting en- zyme inhibitors compared with placebo were secondary … Several studies compared persons with screening- detected diabetes with persons without diabetes.
  3. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/colorectal-cancer-screening-june-2016
    June 15, 2016 - Tests were compared using similar cutoff values expressed in μg hemoglobin (Hb)/g feces. … Based on intention-to-treat analyses, compared with no screening, biennial screening with Hemoccult II … One fair-quality diagnostic accuracy study (n = 9989) evaluated Cologuard compared with OC FIT-CHEK. … Only 2 studies compared harms other than perforation and bleeding in persons who had a colonoscopy vs … Test characteristics of faecal immunochemical tests (FIT) compared with optical colonoscopy.
  4. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary21/depression-in-children-and-adolescents-screening-2009
    March 15, 2009 - in treatment groups, 36 percent to 69 percent met response criteria at postintervention follow-up, compared … higher short-term response rates or a greater reduction in depression symptoms after interventions compared … One trial tested the effect of psychotherapy plus an SSRI (fluoxetine) compared with a placebo-control … Therefore, it is uncertain whether combined therapy would lead to a slight increase in suicidality compared … Two recent comparative efficacy trials compared combined therapy with SSRI treatment alone, and neither
  5. www.uspreventiveservicestaskforce.org/uspstf/recommendation/depression-screening-1996
    January 01, 1996 - For example, when compared to the diagnosis of major depression in primary care patients using a standardized … 97% and a specificity of 63% at a cutoff score of 50. 24 A recent meta-analysis of 18 studies that compared … that the early detection and treatment of depression in primary care leads to improved outcome when compared … improvement in rigorously assessed psychiatric outcome in primary care patients screened, treated, and compared
  6. www.uspreventiveservicestaskforce.org/uspstf/recommendation/depression-screening-2002
    May 07, 2002 - providers generally increased recognition of depression, especially major depression, by a factor of 2 to 3 compared … treatment advice or other system supports reported increased treatment rates in the intervention group compared … All three trials that compared the effects of integrated recognition and management programs with usual … improved symptoms at 12 months; one of these also showed more employment retention in intervention compared
  7. www.uspreventiveservicestaskforce.org/home/getfilebytoken/BM-D2tSCN9U8uuBFAufXaa
    August 01, 2013 - caries) by primary care clinicians in preventing future dental caries and associated complications, compared … Benefits and Harms of Screening No randomized trial or observational study compared clinical outcomes … with existing dental disease was associ- ated with increased risk of subse- quent dental procedures compared … Two studies compared xylitol to topical fluoride (Table 3).23,26 A cluster FIGURE 2 Literature flow … Other trials evaluated methods of topical fluoride application not used in the United States or compared
  8. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
    August 20, 2024 - For supplementation, interventions were oral iron supplementation or iron-fortified foods compared with … For the screening framework, studies compared screening with no screening or treatment with no treatment … Sixteen trials (in 26 publications) compared the effects of routine preventive iron supplementation vs … One fair-quality, US-based observational study (n = 20,690) added for this update compared the association … As in the prior USPSTF review, maternal iron supplementation, compared with placebo or no supplements
  9. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Xbtq4oDQwVo7KgmSjnnDbz
    November 01, 2021 - or 2-time flexible sigmoidoscopy (n = 458 002) were associated with decreased CRC-specific mortality compared … Tests were compared using similar cutoff values ex- pressed in μg hemoglobin (Hb)/g feces. … Only 2 studies compared harms other than perforation and bleeding in persons who had a colonoscopy vs … Population based randomized study of uptake and yield of screening by flexible sigmoidoscopy compared … Test characteristics of faecal immunochemical tests (FIT) compared with optical colonoscopy.
  10. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/obesity-in-children-and-adolescents-screening
    June 18, 2024 - Discontinuation due to adverse effects occurred in 10.4% in the larger trial of liraglutide comparedCompared with placebo, glucagon-like peptide-1 agonists and phentermine/topiramate showed larger effects … Semaglutide use was associated with zBMI reductions in this range, with a 1.1-point zBMI reduction (compared … Clinical efficacy of group-based treatment for childhood obesity compared with routinely given individual … with placebo after 12 mo but a slightly larger improvement in DBP compared with placebo (mean difference
  11. www.uspreventiveservicestaskforce.org/uspstf/recommendation/hepatitis-c-screening
    March 02, 2020 - found small, short-term improvements in quality of life scale scores after treatment with a DAA regimen compared … membranes (>6 hours) was associated with increased risk of HCV transmission in 189 mother-infant pairs compared … internal fetal monitoring was associated with an increased risk of vertical transmission of HCV infection compared … 73.3%. 1 Rates of serious adverse events (1.9%) and withdrawal due to adverse events (0.4%) were low compared … specific adverse events ranged from 2.4% for anemia to 18.4% for headache and were also lower when compared
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/6fFns4N2J-t5EGC5BUdRuu
    October 23, 2023 - Twelve trials com- pared TDF/FTC or tenofovir disoproxil fumarate alone with pla- cebo, 2 trials compared … the dapivirine vaginal ring with placebo, 1 trial compared TAF/FTC with TDF/FTC, and 2 trials compared … One trial, DISCOVER (n = 5387), compared PrEP with oral TAF/FTC vs TDF/FTC. … Cabotegravir was associated with increased weight gain compared with TDF/FTC (mean differences, 0.86 … = .8041 and 18.2% [14/77] vs 16.1% [9/56]; P = .75).43 In the HPTN 083 and HPTN 084 trials, which compared
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/T6Tquunynv3tWM65BFash2
    October 01, 2015 - Compared with usual care or controls, behavioral interventions can increase rates of smoking abstinence … advice significantly increased smoking abstinence compared with minimal advice (RR, 1.37 [CI, 1.20 to … Smaller subsets of studies from these reviews di- rectly compared types of pharmacotherapy for smok- … Two studies (n = 778) compared NRT and varenicline and found no significant difference between groups … Compared with con- trol participants (most often defined as usual care or less intensive interventions
  14. www.uspreventiveservicestaskforce.org/uspstf/recommendation/physical-activity-promotion-behavioral-counseling-1996
    January 01, 1996 - relative risk of death from CHD of 1.9 (95% confidence interval, 1.6 to 2.2) for sedentary persons compared … development of significant weight gain for persons in lower leisure-time physical activity categories compared … for mood enhancement. 74 Third, several recent studies have shown diminished gain at high intensity compared … A trial of middle-aged men compared the training effect of 30 minutes of moderate physical activity with … of the relative risk of triggering myocardial infarctions within 1 hour of heavy physical activity compared
  15. www.uspreventiveservicestaskforce.org/home/getfilebytoken/BnHj53HwgSBNXMvnyavxfS
    January 26, 2016 - One study in general adults directly compared screening with usual care case-finding,9 while the other … None of the trials simply compared usual care with screening plus usual care. … Trials in postpartum women showed 28% to 59% reductions in risk of depression at follow-up compared with … with CBT (DerSimonian and Laird pooled relative risk, 1.34 [95% CI, 1.19-1.50]; K = 10; I2 = 7.9%) compared … The 2009 USPSTF review found 7 studies that compared suicide-related events in adults who received SSRIs
  16. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/osteoporosis-screening
    January 14, 2025 - and major osteoporotic fracture (pooled RR, 0.94 [95% CI, 0.88-0.99]; 3 RCTs; 42,009 participants) comparedCompared with placebo, bisphosphonates (pooled RR, 0.67 [95% CI, 0.45-1.00]; 6 RCTs; 12,055 participants … Compared with placebo, no statistically significant associations were observed for adverse events. … Twenty-one RCTs (reported in 27 articles 159-185 ) compared bisphosphonates (alendronate, ibandronate … , risedronate, or zoledronic acid) with placebo, and 6 RCTs (reported in 9 articles 186-194 ) compared
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/qWZxPBqpffTYVNvGYPkohz
    May 01, 2021 - 2016 NSCH, anxiety conditions were most common in older children and adolescents (aged 12 to 17 years) compared … The 2016 NSCH also found that anxiety conditions were more com- mon in non-Hispanic White children compared … premature mortality.23-26 Anxiety problems are more common in older children (aged 12 to 17 years) compared … 95% CI, 1.48 to 4.88]; n = 321; 4 trials; I2 = 48%), and loss of diagnosis (RR range, 3.02 to 3.09), compared … The evidence on pharmacotherapy compared with placebo was associated with an increased improvement in
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Rm4E5SooP2GnqJ_HVRA5M4
    January 01, 2017 - No RCTs compared screening with no screening. … Meta-analysis found that continuous positive airway pressure (CPAP) compared with sham was significantly … The meta-analyses found that CPAP was associated with reduction of AHI compared with sham CPAP (WMD, … screening compared with no screening. … Improvement of mild sleep-disordered breathing with CPAP compared with conservative therapy.
  19. www.uspreventiveservicestaskforce.org/home/getfilebytoken/b-rsH7WPpNC3uL9NeoXBfF
    May 08, 2018 - Compared with conservative approaches, active treatments for screen-detected prostate cancer have unclear … Three RCTs (n = 2524) 6 6 - 6 8 and 11 cohort studies (n = 8809)10,11,69-78 compared harms among men … treated with radi- cal prostatectomy compared with conservative management, and 6 uncontrolled studies … Urinary Incontinence After Radiation Therapy Compared With Conservative Management (Key Question 4)a … Erectile Dysfunction After Radiation Therapy Compared With Conservative Management (Key Question 4)a
  20. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary17/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing-2013
    December 15, 2013 - The sensitivity of the RST was high compared with that of the Breast and Ovarian Analysis of Disease … The PAT had 100% sensitivity compared with Myriad II 39 , and the FHS-7 had 88% sensitivity compared … with noncarriers 87 , 89 or compared with women who were not tested 90 , and women with a family … history that indicates high risk for breast cancer compared with untested low-risk women 76 . … Tamoxifen increased endometrial cancer and cataracts compared with raloxifene.

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