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161. Archived: Addendum to Screening for Ovarian Cancer: Evidence Update for the U.S. Preventive Services Task Force Reaffirmation Recommendation Statement: Ovarian Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/addendum-to-screening-for-ovarian-cancer-evidence-update-for-the-us-preventive-services-task-force-reaffirmation-recommendation-statement/ovarian-cancer-screening-2012
     April 15, 2012 - CA-125 testing and transvaginal ultrasonography did not improve cancer-specific or overall mortality compared … cancer with CA-125 testing and transvaginal ultrasonography did not reduce ovarian cancer mortality compared … No reduction in ovarian cancer mortality was observed in the intervention group compared with those receiving … The two screened groups were compared using cancer diagnoses identified through June 13, 2008. … Sensitivity was also higher for the MMS group compared with the USS group, although not significantly

162. Addendum to Screening for Ovarian Cancer: Evidence Update for the USPSTF Reaffirmation Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/QtuWfedsMmUb_sAuKWdsGg
     December 31, 2014 - 125 testing and transvaginal ultrasonography did not improve cancer-specific or overall mortality compared … No reduction in ovarian cancer mortality was observed in the intervention group compared with those … The two screened groups were compared using cancer diagnoses identified through June 13, 2008. … Sensitivity was also higher for the MMS group compared with the USS group, although not significantly … be noted that results have been presented from the baseline prevalence screening only and not yet compared

163. Overview of Prostate Cancer Screening Decision Models: A Contextual Review for the U.S. Preventive Services Task Force (pdf file)
     www.uspreventiveservicestaskforce.org/Home/GetFile/1/16813/prostate-cancer-models-overview/pdf
     May 01, 2018 - This was a relative reduction of 24.8% in the probability of prostate cancer deaths compared with the … The strategies presented were chosen to reduce the harms (i.e., overdiagnosis) by more than half (compared … , PLCO control, ERSPC screening, and PLCO screening arms, respectively, over 11 years of follow-up compared … Lastly, two publications using the same model, a seven-stage Markov model using U.S. data, compared … Is combined androgen blockade with bicalutamide cost-effective compared with combined androgen blockade

164. Archived: Final Evidence Summary: Dental Caries in Children from Birth Through Age 5 Years: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary2/dental-caries-in-children-from-birth-through-age-5-years-screening-2014
     June 15, 2013 - caries) by primary care clinicians in preventing future dental caries and associated complications, compared … Benefits and Harms of Screening No randomized trial or observational study compared clinical outcomes … Xylitol Three trials compared xylitol to no xylitol ( Table 3 ) 29 , 30 , 35 . … Two studies compared xylitol to topical fluoride ( Table 3 ) 23 , 26 . … Other trials evaluated methods of topical fluoride application not used in the United States or compared

165. Recommendation: Weight Loss to Prevent Obesity-Related Morbidity and Mortality in Adults: Behavioral Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-adults-interventions
     September 18, 2018 - maintenance interventions are associated with less weight gain after the cessation of interventions, compared … weight loss intervention groups demonstrated greater weight loss and decreased waist circumference compared … At 12 to 18 months, intervention participants were more likely to lose 5% of their initial weight compared … needed to treat = 8). 1 Participants in weight loss maintenance interventions had less weight gain compared … by 12 months, with 80% to 96% of participants experiencing an adverse event in the medication group compared

166. Recommendation: Skin Cancer Prevention: Behavioral Counseling | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/skin-cancer-counseling
     March 20, 2018 - that addressed sun protection behavior composite scores in adults found an increase in such behaviors compared … using an appearance-focused intervention among young female adults noted a significant improvement compared … Overall, melanoma risk was reduced in the intervention group compared with the control group and was … most pronounced for invasive melanoma compared with in situ melanoma. 34 A large US case-control study … also demonstrated a lower likelihood of melanoma in persons routinely using sunscreen compared with

167. Draft Recommendation: Syphilis Infection During Pregnancy: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/syphilis-infection-pregnant-persons
     November 19, 2024 - Native American/Alaska Native mothers in 2021 were up to 8 times more likely to have congenital syphilis compared … fewer adverse pregnancy outcomes among pregnant persons screened and treated for syphilis infection compared … and neonatal death was dramatically reduced in pregnant persons treated for syphilis during pregnancy compared … and ranged from 7% to 26%. 28-29 , 31 One additional study evaluated use of a syphilis immunoassay compared … Together, these reported false-positive rates reflect results after a single step of testing, compared

168. Screening for Cervical Cancer in Primary Care: A Decision Analysis for the U.S. Preventive Services Task Force (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/HZGtYqL_8u57Gkc6YFctmT
     August 21, 2018 - RESULTS Compared with no screening, all modeled cervical cancer screening strategies were estimated to … Strategies The analysis focused on the comparative effectiveness and harms of primary hrHPV testing, compared … as the additional number of colposcopies divided by the additional life-years of a specific strategy compared … Compared with no screening, all modeled cer- vical cancer screening strategies were estimated to result … alone every 3 years from ages 21 to 65 years (strategy 1), with 3 colposcopies per life-year gained compared

169. Screening for Impaired Visual Acuity in Older Adults: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/DCfAJZvNDzSYu7NqLJX2bv
     March 01, 2016 - Four studies18,21,24,25 found no visual acuity test had both high sensitiv- ity and specificity compared … of patients with cataract and 75% of patients with AMD were correctly identified by a geriatrician compared … A third study (n = 371) compared the scores on the Minimum Data Set (MDS) 2.0 Vision Patterns section … One study found the Amsler grid is not accurate for identifying presence of vision conditions compared … Good Wet AMD: VEGF inhibitors More cases of endophthalmitis and uveitis compared with placebo, but

170. Screening for Speech and Language Delay in Preschool Children: Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/ecWjjTgXCffjwPyqgNCEpR
     February 01, 2006 - Few studies compared the performance of ≥ 2 tests, compared a single screening technique across different … However, one good-quality RCT compared 12 months of a clinician-directed speech and language intervention … improvements in the speech and language skills of the 3-to-5-year-olds who had received interventions compared … the primary care setting to screen children in this age group; 2) assessing the effect of earlier compared … Two Language Screening Tests Compared with Developmental Sentence Scoring.

171. Behavioral Counseling in Primary Care to Promote Physical Activity - Recommendations and Rationale (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/ngSKuH6MP9L_BSuX-Pp2K6
     January 01, 2010 - There were no completed trials with children or adolescents that compared counseling with usual care … insufficient evidence regarding the potential harms of various activity protocols, such as moderate compared … The 6 trials of fair to good quality that compared physical activity counseling protocols to usual care … Two fair to good quality randomized trials compared 2 or more different interventions aimed at increasing … studies examining the effectiveness of physical activity counseling for children or adolescents that compared

172. Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia: US Preventive Services Task Force Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/8uE22djVfm8hF8wNg7wWYn
     May 01, 2021 - 1999 to 2010, pregnant persons who were food insecure had lower mean iron in- take from supplements compared … and preeclampsia (adjusted OR, 1.44 [95% CI, 1.16-1.76] and 1.45 [95% CI, 1.26-1.67], respectively) compared … significant differ- ences on rates of hypertensive disorders of pregnancy with iron supplementation compared … CI, 0.67-1.31]; I2 = 75.5%).1,17 A pooled analysis reported few differences between supplementation compared … sepa- rate trial (n = 111), nonadherence to iron therapy was lower in adults taking supplementation compared

173. Recommendation: Lung Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/lung-cancer-screening
     March 09, 2021 - Three retrospective studies compared how various approaches for nodule classification would alter the … The CISNET modeling studies commissioned by the USPSTF thus compared the benefits and harms of screening … Currently, there are no studies that have prospectively compared the use of USPSTF criteria considering … Several studies suggest that, compared with no screening, individuals who receive LDCT screening do not … Patients with localized disease have a 59% 5-year survival rate, compared with 32% for those with regional

174. Screening for Chlamydial and Gonococcal Infections: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/k-btyK4W2-v9KnemTK8WDx
     September 14, 2021 - Chlamydia screening compared with no screening was significantly associated with reduced risk of pelvic … good-quality cluster randomized trial that evaluated the effectiveness of screening for chlamydia compared … No study compared clinician- and self- collected testing for chlamydial or gonorrhea infections at other … False-positive rates in studies that compared self-collected and clinician-collected samples ranged … gonorrhea diagnosis were both highly sensitive,29,34,37 but no studies meeting inclusion criteria compared

175. Archived: Final Evidence Summary: Breastfeeding: Counseling, July 2003 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/breastfeeding-counseling-2003
     July 01, 2003 - Table 1 summarizes the results of the RCTs of education, support, and written materials compared with … Compared with support alone, studies that combined breastfeeding education and support produced larger … One of these studies 44 compared 4 separate clinics each with a different intervention regime: Peer … Another study 46 compared 2 clinics that had peer counselors with 6 clinics that did not. … In this study, 55 of 59 (93%) women in the intervention group initiated breastfeeding compared with 30

176. The Effectiveness of Primary Care-Based Interventions to Promote Breastfeeding: Evidence Review and Meta-Analysis (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/6-CojmU4NZFXUKggs-_YFU
     January 01, 2010 - Table 1 summarizes the results of the RCTs of education, support, and written materials compared with … Compared with support alone, studies that combined breastfeeding education and support produced larger … One of these studies44 compared 4 separate clinics each with a different intervention regime: (1) peer … Another study46 compared 2 clinics that had peer counselors with 6 clinics that did not. … In this study, 55 of 59 (93%) women in the intervention group initiated breastfeeding compared with 30

177. Archived: Final Recommendation Statement: Screening for Depression in Adults | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/depression-in-adults-screening
     January 26, 2016 - One study in general adults directly compared screening with usual care case-finding, 9 while the other … None of the trials simply compared usual care with screening plus usual care. … Trials in postpartum women showed 28% to 59% reductions in risk of depression at follow-up compared with … point or greater reduction in 9-item PHQ score (an improvement considered to be clinically important) compared … The 2009 USPSTF review found 7 studies that compared suicide-related events in adults who received SSRIs

178. Archived: Evidence Summary: NSAIDs: Aspirin/NSAIDs for Prevention of Colorectal Cancer: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-nsaids/aspirin-nsaids-for-prevention-of-colorectal-cancer-preventive-medication-2007
     March 15, 2007 - Compared with non-ASA NSAIDs, COX-2 inhibitors reduce this risk but, in multiyear use, have a higher … significant trend for greater reduction in adenoma incidence was observed with celecoxib, 800 mg/d, compared … a nonsignificant trend toward greater adenoma reduction with more than 19 years of use of any NSAID compared … with placebo or naproxen but not when compared with nonnaproxen, non-ASA NSAIDs. … Furthermore, the cost-effectiveness of chemoprevention needs to be considered carefully and compared

179. Recommendation: Prediabetes and Type 2 Diabetes: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/screening-for-prediabetes-and-type-2-diabetes
     August 24, 2021 - Based on data suggesting that the incidence of diabetes increases at age 35 years compared with younger … Neither trial found a reduction in all-cause or type-specific mortality with screening compared with … Effect of Interventions for Prediabetes on Progression to Diabetes Twenty-three trials compared lifestyle … The DPP (n = 2155) reported greater decreases in weight for persons receiving metformin compared with … Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and

180. Screening for Intimate Partner Violence and Caregiver Abuse of Older or Vulnerable Adults: US Preventive Services Task Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/_q6ZTL2Yg6f6rLp-Re9whD
     June 24, 2025 - 45%) report experiencing psychological aggression by an intimate partner in their lifetime.1,3 Women, compared … - ability, are more likely to experience violent victimization and mal- treatment regardless of age compared … Slapped, Things, Threaten tool in detecting lifetime IPV, sensitivity was 96% and specificity was 75%, compared … group.1,35 In 1 study, IPV events were lower in the intervention group (7.50 events per person-year) compared … Five trials reported on specific categories of IPV.1,35 Generally, compared with studies enrolling pregnant