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  1. 04-E029-1 Summary (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-surveillance_executive.pdf
    December 01, 2011 - One study reported the following: compared to the pre-PSA era (1986), the incidence rates in 2005 were … A single study investigated trends in incidence stratified by T stage, and demonstrated that compared … The second study demonstrated that, compared to patients with well differentiated tumors, patients with … to RP and BT, but lower costs compared to intensity modulated RT (IMRT) and proton beam RT. … They also reported higher rates of urinary strictures in men treated with RT compared with men on WW.
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections-surveillance-140925.pdf
    January 01, 2014 - For Key Question 1, included studies needed to have used clinical stool specimen, compared at least … Immunoassays for toxins A and B Level of Evidence: Low to moderate •Ten studies directly compared … Of these, 28 were correctly identified compared to the reference standard. … Seegene Seeplex ACE PCR assay; compared to toxigenic culture. … For those with prior VRE, the chance in concentration was compared.
  3. effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_2.pdf
    May 01, 2020 - • Routine amniotomy plus oxytocin does not differ compared with control treatment in cesarean delivery … • Administration of intravenous fluids compared with oral intake alone demonstrated a reduction in … • Pulsatile administration of oxytocin is associated with a longer duration of labor compared with … • There is limited evidence that immediate pushing has a shorter labor duration when compared to … to 4 hours, had higher cesarean delivery rates; but otherwise the use of a partogram compared with
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_surveillance.pdf
    January 30, 2013 - and n=42).10,11 Prolongation of Pregnancy The strength of evidence favoring SQ terbutaline pump compared … ).15 Other Matria-based studies reported statistically significant benefits in favor of the pump compared … women with singleton gestation and RPTL demonstrated highly unreliable odds favoring no treatment compared … the   Source: www.effectivehealthcare.ahrq.gov Published online: January 30, 2013 23   compared … Neonatal hypoglycemia was reported in only one RCT that compared the SQ terbutaline pump with placebo
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_surveillance.pdf
    January 30, 2013 - and n=42).10,11 Prolongation of Pregnancy The strength of evidence favoring SQ terbutaline pump compared … ).15 Other Matria-based studies reported statistically significant benefits in favor of the pump compared … women with singleton gestation and RPTL demonstrated highly unreliable odds favoring no treatment compared … the   Source: www.effectivehealthcare.ahrq.gov Published online: January 30, 2013 23   compared … Neonatal hypoglycemia was reported in only one RCT that compared the SQ terbutaline pump with placebo
  6. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
    September 01, 2011 - One compared ECT and rTMS, and the other compared ECT and ECT plus rTMS. … Three fair trials compared rTMS with a sham procedure and found no significant differences. … Evidence for ECT compared with rTMS indicated higher rates of overall withdrawals in the ECT compared … Two Tier 1 trials compared rTMS with sham. All findings provided low strength of evidence. … No trials directly compared the likelihood of maintaining remission for nonpharmacologic interventions
  7. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia_executive.pdf
    May 01, 2006 - difference; over 50 percent of patients treated with epoetin or darbepoetin had a Hb increase >2 g/dL, compared … control showed approximately 30 percent of patients treated with epoetin or darbepoetin were transfused, compared … Results of this fixed-effects meta-analysis were compared with random-effects meta-analysis; results … patients treated with epoetin or darbepoetin experienced a thromboembolic event, compared with 4 percent … No trials compared criteria for discontinuing therapy.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_addendum.pdf
    February 01, 2010 - Coronary artery bypass surgery compared with percutaneous coronary interventions for multivessel disease … Although the procedures have been compared in several randomized trials, their long-term effects on … We excluded trials that compared either method alone with medical therapy, those that compared two … forms of PCI, and those that compared two forms of CABG. … Within 90 days of randomization, 75 (2%) of 3889 patients assigned to CABG died, compared with 74 (
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-evidence-summary.pdf
    August 01, 2018 - Lithium improved acute mania in the short-term and prolonged time to relapse in the long-term compared … For drugs not approved for BD, paliperidone also improved acute mania compared to placebo (low-strength … Participants using carbamazepine reported more severe rash and number of adverse events compared to … Systematic/collaborative care had no effect on relapse compared to inactive comparators (low-strength … for mania, and benefit for lithium compared with placebo for maintenance.52-54 Cochrane reviews have
  10. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive-2007.pdf
    January 01, 2007 - The systematic review included all studies of patients with atherosclerotic RAS (ARAS) that compared … patients with severe hypertension. 2 (i.e., antihypertensive, antiplatelet, and antilipid treatment) compared … Notably, only two trials have compared angioplasty (without stent placement) with medical therapy and … An analysis of a previously reported randomized trial that compared immediate angioplasty and either
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0334_08-04-2010.pdf
    January 01, 2010 - indicated interest in whether a genetic testing strategy could lead to improvements in health outcomes compared … of genetic testing for CYP2C19 variants in patients who are candidates for clopidogrel treatment, compared … patients who require antiplatelet therapy for the prevention of major adverse cardiovascular outcomes, compared
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
    June 13, 2013 - Among studies that directly compared one type of troponin assays (troponin I, troponin T, hs troponin … Among studies that directly compared troponin testing in patients with CKD versus patients with normal … Among studies that directly compared one type of troponin assays (troponin I, troponin T, hs troponin … If there are studies that directly compared the utility of troponin elevation for diagnosis of ACS in … • If there are studies that directly compared different types of troponin assays with each other
  13. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear_executive.pdf
    July 01, 2010 - increasing age; 54 percent of patients over the age of 60 years have a partial or complete RC tear compared … Does early surgical repair compared to late surgical repair (i.e., nonoperative intervention followed … Does operative repair compared with nonoperative treatment lead to improved health-related quality of … Six studies compared single-row versus double-row fixation of repairs, providing moderate evidence of … Five studies compared nonoperative to operative treatments, with a median sample size of 103 (IQR: 40
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-anticholinergic-medicines_research.pdf
    December 01, 2009 - Eighth, treatments were compared among patients with propensity scores from 0.4 to 0.7. … This was a four year, multinational, randomized controlled trial that compared tiotropium to placebo … The strength of the present study is that, compared with a randomized trial, we evaluated effects of … Unadjusted rate of events per 100 person-years by medication regimen compared to ICS + LABA Crude … Unadjusted rate of events per 100 person-years by medication regimen compared to ICS + LABA * Rates
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-234-headaches-pregnancy-summary.pdf
    November 01, 2020 - Compared with nonuse (either during or before pregnancy), triptan use may not be associated with spontaneous …  A single primary study found that compared with oral codeine, combination metoclopramide and diphenhydramine … randomized controlled trials, 8 nonrandomized comparative studies [i.e., observational studies that compared … with spontaneous abortion, elective or induced abortion, or major or minor congenital anomalies, compared … Treatment—antiemetics (dopamine receptor antagonists), antihistamines, and opioids: One RCT found that, compared
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_surveillance.pdf
    December 31, 2013 - (High) When compared with DPP-4 inhibitors, No new studies identified on DPP-4 No issues identified. … (Moderate) metformin compared to metformin monotherapy.12 incorporated. be updated with new data … The effect of initial therapy with the fixed-dose combination of sitagliptin and metformin compared … Exenatide plus metformin compared with metformin alone on β-cell function in patients with Type 2 … Gallwitz B, Rosenstock J, Rauch T, et al. 2-year efficacy and safety of linagliptin compared with
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear-surveillance-140925.pdf
    February 01, 2014 - • Key question # 4: Does operative repair compared with nonoperative treatment lead to improved … One study compared early surgical repair versus late surgical repair after failed nonoperative … Patients receiving early surgery had superior function compared with the delayed surgical group; … to repair (UCLA No Signal 1 MA in CER included 3 non-RCTs (cohort studies) which compared … Patients receiving early surgery had superior function compared with the delayed surgical group;
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
    June 01, 2018 - The Key Questions Question 1: What are the benefits and harms for antipsychotics compared to each other … What are the benefits and harms for antipsychotics compared to each other, placebo, or non-drug approaches … What are the benefits and harms for antipsychotics compared to each other, placebo, or non-drug approaches … What are the benefits and harms for antipsychotics compared to each other, placebo, or non-drug approaches … What are the benefits and harms for antipsychotics compared to each other, placebo, or non-drug approaches
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
    March 01, 2013 - (Low) Less improvement in disease activity (ACR 50) for anakinra compared with etanercept and compared … (Low) Greater improvement in disease activity (ACR 50) for etanercept compared with abatacept, adalimumab … No significant differences when compared with golimumab. … (Low) Less improvement in disease activity (ACR 50) for anakinra compared with etanercept and compared … No significant differences when compared with golimumab. (Low) Biologic DMARDs vs.
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
    March 01, 2013 - (Low) Less improvement in disease activity (ACR 50) for anakinra compared with etanercept and compared … (Low) Greater improvement in disease activity (ACR 50) for etanercept compared with abatacept, adalimumab … No significant differences when compared with golimumab. … (Low) Less improvement in disease activity (ACR 50) for anakinra compared with etanercept and compared … No significant differences when compared with golimumab. (Low) Biologic DMARDs vs.

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