-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections-surveillance-140925.pdf
January 01, 2014 - For Key
Question 1, included studies needed to have used clinical stool specimen, compared at least … Immunoassays for toxins A
and B
Level of Evidence: Low to
moderate
•Ten studies directly compared … Of these, 28 were correctly identified
compared to the reference standard. … Seegene
Seeplex ACE PCR
assay; compared to
toxigenic culture. … For those with
prior VRE, the
chance in
concentration
was compared.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_surveillance.pdf
January 30, 2013 - and n=42).10,11
Prolongation of Pregnancy
The strength of evidence favoring SQ
terbutaline pump compared … ).15 Other Matria-based
studies reported statistically
significant benefits in favor of the
pump compared … women with singleton
gestation and RPTL demonstrated
highly unreliable odds favoring no
treatment compared … the
Source: www.effectivehealthcare.ahrq.gov
Published online: January 30, 2013
23
compared … Neonatal
hypoglycemia was reported in only one RCT that compared
the SQ terbutaline pump with placebo
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_surveillance.pdf
January 30, 2013 - and n=42).10,11
Prolongation of Pregnancy
The strength of evidence favoring SQ
terbutaline pump compared … ).15 Other Matria-based
studies reported statistically
significant benefits in favor of the
pump compared … women with singleton
gestation and RPTL demonstrated
highly unreliable odds favoring no
treatment compared … the
Source: www.effectivehealthcare.ahrq.gov
Published online: January 30, 2013
23
compared … Neonatal
hypoglycemia was reported in only one RCT that compared
the SQ terbutaline pump with placebo
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
September 01, 2011 - One compared ECT
and rTMS, and the other compared ECT and ECT plus
rTMS. … Three fair trials compared rTMS
with a sham procedure and found no significant
differences. … Evidence for ECT compared with rTMS indicated
higher rates of overall withdrawals in the ECT
compared … Two Tier 1 trials compared rTMS
with sham. All findings provided low strength of
evidence. … No trials directly compared the likelihood of
maintaining remission for nonpharmacologic
interventions
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia_executive.pdf
May 01, 2006 - difference; over 50 percent of patients treated with
epoetin or darbepoetin had a Hb increase >2 g/dL,
compared … control showed approximately 30 percent of
patients treated with epoetin or darbepoetin were
transfused, compared … Results of this fixed-effects meta-analysis were
compared with random-effects meta-analysis; results … patients treated with epoetin or darbepoetin
experienced a thromboembolic event, compared
with 4 percent … No trials compared criteria for discontinuing
therapy.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive-2007.pdf
January 01, 2007 - The systematic review
included all studies of patients with
atherosclerotic RAS (ARAS) that
compared … patients with severe hypertension.
2
(i.e., antihypertensive, antiplatelet, and antilipid
treatment) compared … Notably, only two trials have compared
angioplasty (without stent placement) with medical
therapy and … An analysis of a previously reported randomized trial
that compared immediate angioplasty and either
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-evidence-summary.pdf
August 01, 2018 - Lithium
improved acute mania in the short-term and prolonged
time to relapse in the long-term compared … For drugs not approved for BD,
paliperidone also improved acute mania compared to
placebo (low-strength … Participants using
carbamazepine reported more severe rash and number of
adverse events compared to … Systematic/collaborative care had no effect on relapse
compared to inactive comparators (low-strength … for
mania, and benefit for lithium compared with placebo
for maintenance.52-54 Cochrane reviews have
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_addendum.pdf
February 01, 2010 - Coronary artery bypass surgery
compared with percutaneous coronary interventions for multivessel disease … Although the procedures have
been compared in several randomized trials, their long-term effects on … We
excluded trials that compared either method alone with medical therapy, those that compared two … forms of PCI, and those that compared two forms of CABG. … Within 90
days of randomization, 75 (2%) of 3889 patients assigned to CABG died, compared with 74
(
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0334_08-04-2010.pdf
January 01, 2010 - indicated interest in whether a
genetic testing strategy could lead to improvements in health outcomes compared … of genetic testing for
CYP2C19 variants in patients who are candidates for clopidogrel treatment,
compared … patients who require antiplatelet therapy for the prevention of major adverse
cardiovascular outcomes, compared
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
June 13, 2013 - Among studies that directly compared one type of troponin assays (troponin I, troponin T, hs
troponin … Among studies that directly compared troponin testing in patients with CKD versus patients
with normal … Among studies that directly compared one type of troponin assays (troponin I, troponin
T, hs troponin … If there are studies that directly compared the utility of troponin elevation for diagnosis of ACS
in … • If there are studies that directly compared different
types of troponin assays with each other
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear_executive.pdf
July 01, 2010 - increasing age; 54
percent of patients over the age of 60 years
have a partial or complete RC tear
compared … Does early surgical repair compared to late
surgical repair (i.e., nonoperative intervention
followed … Does operative repair compared with nonoperative
treatment lead to improved health-related quality
of … Six studies compared single-row
versus double-row fixation of repairs, providing
moderate evidence of … Five
studies compared nonoperative to operative treatments,
with a median sample size of 103 (IQR: 40
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-anticholinergic-medicines_research.pdf
December 01, 2009 - Eighth, treatments were compared
among patients with propensity scores from 0.4 to 0.7. … This was a
four year, multinational, randomized controlled trial that compared tiotropium to placebo … The strength of the present study is that, compared with a randomized trial, we
evaluated effects of … Unadjusted rate of events per 100 person-years by medication regimen compared to ICS +
LABA
Crude … Unadjusted rate of events per 100 person-years by medication regimen compared to ICS + LABA
* Rates
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_surveillance.pdf
December 31, 2013 - (High)
When compared with DPP-4 inhibitors, No new studies identified on DPP-4 No issues identified. … (Moderate) metformin compared to metformin
monotherapy.12
incorporated. be updated
with new
data … The effect of initial therapy with
the fixed-dose combination of
sitagliptin and metformin compared … Exenatide plus metformin
compared with metformin alone on
β-cell function in patients with Type
2 … Gallwitz B, Rosenstock J, Rauch T,
et al. 2-year efficacy and safety of
linagliptin compared with
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear-surveillance-140925.pdf
February 01, 2014 - • Key question # 4: Does operative repair compared with nonoperative treatment lead to
improved … One study
compared early
surgical repair
versus late surgical
repair after failed
nonoperative … Patients receiving
early surgery had
superior function
compared with the
delayed surgical
group; … to
repair (UCLA
No Signal
1 MA in CER
included 3
non-RCTs
(cohort
studies) which
compared … Patients receiving
early surgery had
superior function
compared with the
delayed surgical
group;
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
June 01, 2018 - The Key Questions
Question 1: What are the benefits and harms for antipsychotics compared to each other … What are the benefits and harms for antipsychotics compared to each other,
placebo, or non-drug approaches … What are the benefits and harms for antipsychotics compared to each other,
placebo, or non-drug approaches … What are the benefits and harms for antipsychotics compared to each other,
placebo, or non-drug approaches … What are the benefits and harms for antipsychotics compared to each other,
placebo, or non-drug approaches
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - (Low) Less
improvement in disease activity (ACR 50) for
anakinra compared with etanercept and
compared … (Low) Greater
improvement in disease activity (ACR 50) for
etanercept compared with abatacept,
adalimumab … No
significant differences when compared with
golimumab. … (Low) Less improvement in
disease activity (ACR 50) for anakinra compared with
etanercept and compared … No significant differences when compared with
golimumab. (Low)
Biologic DMARDs vs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - (Low) Less
improvement in disease activity (ACR 50) for
anakinra compared with etanercept and
compared … (Low) Greater
improvement in disease activity (ACR 50) for
etanercept compared with abatacept,
adalimumab … No
significant differences when compared with
golimumab. … (Low) Less improvement in
disease activity (ACR 50) for anakinra compared with
etanercept and compared … No significant differences when compared with
golimumab. (Low)
Biologic DMARDs vs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
July 01, 2014 - How do pharmacological treatments affect maternal and
childa outcomes when compared with placebo or … How do pharmacological treatments affect maternal and
childa outcomes when compared with each other … How do pharmacological treatments affect maternal
and childa outcomes when compared with placebo or … How do pharmacological treatments affect maternal and
child outcomes when compared with each other ( … • The drugs in Table A compared with each other
• Any nonpharmacological treatment.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
January 01, 2014 - Cadexomer iodine dressings produced modest
improvements in wound healing rates and wound area
compared … Silver dressings did not improve wound healing
compared with non-silver dressings. … Surgical procedures targeting superficial vein
reflux produced similar rates of wound healing
compared … Silver dressings did not improve wound healing
compared with non-silver dressings. … Insufficient
2a What are the benefits and harms of systemic antibiotics compared with compression?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_surveillance.pdf
January 01, 2013 - A study that compared TD-OCT and SD-
OCT found that AUC were comparable
for both the SD and TD-OCT. … Medeiros et al. (2004) compared
RNFL photography with the GDx with
VCC in 42 participants with OAG, … At
One new study that assessed the use of
iCare rebound tonometry compared with
None found
5 … Bagga et al. (2006) compared
the ability of various tests of structure
and function to discriminate … concluded that sensitivity results at the
common cutoff point for each test
One study compared the